Biomedical Facilities
The Faculty of Medical Sciences has a broad range of biomedical and clinical research facilities.
BioImaging
BioImagingThe BioImaging Unit operates several sites across the University, and provides a wide range of state-of-the-art microscopy equipment.
Imaging capabilities available in the Facility include: conventional brightfield; phase; DIC and widefield-fluorescence; and confocal microscopy.
Bio Screening
Bio ScreeningThe Bio Screening Facility uses state of the art equipment and biological reagents to cater for researchers working with both mammalian and microbial cell-based systems, and enables the rapid identification of novel targets.
Bioinformatics
BioinformaticsThe Bioinformatics Support Unit (BSU) provides data analysis and experimental design services for next-generation sequencing, microarrays, proteomics and more.
The BSU has expertise in a range of areas, including: high-throughput sequence analysis; microarray analysis; proteomics analysis.
Colour Vision Testing Services
Colour Vision Testing ServicesColour Vision Testing Services provide assessment and classification of colour vision deficiencies, using a comprehensive battery of both standardised and more sophisticated tests initially developed for research purposes.
Electron Microscopy
Electron MicroscopyElectron Microscopy Research Services has a range of specialist equipment for imaging specimens from both biological and material sciences.
The primary services available are:
- Transmission Electron Microscopy (TEM)
- Scanning Electron Microscopy (SEM)
- Gatan 3view
Flow Cytometry
Flow CytometryThe Flow Cytometry Core Facility provides a comprehensive service and houses a large range of high quality equipment, including:
- cell sorters and analysers for performing fluorescence cytometry
- a Helios Cytof Mass Cytometer
- Seahorse XF analyser systems for assessing metabolic activity
Genomics
GenomicsThe Genomics Core Facility supports and delivers cutting-edge genomics research, designed with single-cell sequencing and medium-scale genomics in mind. The Facility's instrumentation set-up allows for a high level of service flexibility, as it is able to be rapidly shifted between genomic, transcriptomic and epigenomic sample analysis.
Human Developmental Biology Resource
Human Developmental Biology ResourceThe Human Developmental Biology Resource (HDBR) is an ongoing collection of human embryonic and fetal material ranging from 3 to 20 weeks of development.
Tissue, slides, RNA/DNA and tissue arrays are available to the international scientific community.
Infectious Diseases
Infectious DiseasesNewcastle University Infectious Diseases Facility provides containment facilities for the safe use and handling of infectious microbiological agents. With two laboratory suites dedicated to the research of HG3 pathogens, the Facility provides the opportunity for scientists to include Hazard Group 3 (HG3) and Specified Animal Pathogen Order Group 3 pathogens in their research.
NanoString nCounter Analysis System
NanoString nCounter Analysis SystemNewcastle Nanostring is a technician-run service with specialist advice available.
The NanoString nCounter analysis system is the first and only platform that can deliver direct profiling of individual molecules in a highly multiplexed single reaction without any need for amplification. Critically, NanoString technology is superior to any other current RNA analysis technique for FFPE-derived material.
Protein and Proteomics Facility
Protein and Proteomics FacilityNewcastle University's Protein and Proteomics Facility (NUPPA) provides a range of services including: identifying single proteins and proteins in complex protein mixtures; characterising proteins; finding post-translational modifications; quantifying proteins.
The latest addition to NUPPA is the Protein Production Unit, adding further expertise and equipment in the production and characterisation of recombinant proteins in prokaryotic host organisms.
Preclinical In Vivo Imaging
Preclinical In Vivo ImagingNewcastle Preclinical In Vivo Imagining (PIVI) is a multidisciplinary research centre providing equipment for Magnetic Resonance, Positron Emission Tomography and Fluorescence/Bioluminescence imaging. The Facility provides a range of services and training, from experimental design and data acquisition, to data analysis.
Spatially Resolved Transcriptomics
Spatially Resolved TranscriptomicsSpatial Transcriptomics is a powerful technology which allows the whole transcriptome to analysed within a positional context; enabling sequencing data to be visualised directly on a tissue histology section.
At Newcastle University we combine the expertise from several discplines to provide the SpaRTAN service: Spatially Resolved Transcriptomics At Newcastle.