Staff Profile
Dr Xiao Wang
Senior Lecturer
- Email: x.n.wang@ncl.ac.uk
- Telephone: +44 (0) 191 208 8792
- Address: Translational and Clinical Research Institute
Leech Building, Medical School
University of Newcastle upon Tyne
NE2 4HH
Background
Qualifications:
- MBBS (1st Hons)
- MSc & Mphil in Immunology & Microbiology
- PhD in Transplantation Immunology
Roles and Responsibilities:
- Principle Investigator in the Regenerative Medicine & Transplantation Group
- MRes Transplantation Programme & Transplantation Module lead
Research interests: Human mesenchymal stem/stromal cells (MSCs) and regulatory T cells (Tregs) - biology and clinical application in regenerative medicine and immune modulation.
Current research projects:
- Mesenchymal stromal cell-derived extracellular vesicles (MSC-EVs) in OA joint tissue repair/regeneration
- Mesenchymal stromal cell-derived extracellular vesicles (MSC-EVs) in immune modulation
- Regulatory T cells and Treg-EVs in DC and T cell modulation in the context of graft-versus-host disease
- Biomarker potential of extracellular vesicles from body fluids
Teaching
Postgraduate Teaching
Postgraduate Teaching
- Programme and Module Lead for Transplantation Sciences in MRes in Medical and Molecular Biosciences
- Supervisor, mentor, and progress reviewer for PhD and Master research programmes
- Internal and external examiner for PhD and Master research Programmes
- Member of MRes and M.Sc Board of Study and Board of Examiners
Undergraduate Teaching
- BSc (Hons) Biomedical Sciences CMB 3000
- Stage 3 Research Project Supervisor and Examiner
Research
Recent research activities:
My research focus is to develop, evaluate, and improve innovative therapeutic strategies using adult stem cells and immunomodulatory cells, including haematopoietic stem cell therapy for haematological and immunological disorders, regulatory T cell therapy for transplant complications, and mesenchymal stem cell therapy for immune regulation and regenerative medicine, with an increasing focus on cellular secretome particularly extracellular vesicles.
Recent research activities:
The role of mesenchymal stem cell-derived extracellular vesicles in immune modulation
The therapeutic potential of using MSC-derived extracellular vesicles in bone and cartilage repair
The effect of mesenchymal stem cell conditioned media on cutaneous wound healing
Human Treg-derived extracellular vesicles and their role in immune modulation
Human Treg mediated transcriptional and functional modulation of dendritic cells
Modulation of graft-versus-host reaction by human Treg using an in vitro human GvHD skin explant model
Funding:
- European Commission FP7 MCITN
- Arthritis Research UK
- Newcastle Healthcare Charities
Publications
- Ahmed SS, Whritenour J, Ahmed MM, Bibby L, Darby L, Wang XN, Watson J, Dickinson AM. Evaluation of a human in vitro skin test for predicting drug hypersensitivity reactions. Toxicology and Applied Pharmacology 2019, 369, 39-48.
- Muller S, Nicholson L, Al Harbi N, Mancuso E, Jones E, Dickinson A, Wang XN, Dalgarno K. Osteogenic potential of heterogeneous and CD271-enriched mesenchymal stromal cells cultured on apatite-wollastonite 3D scaffolds. BMC Biomedical Engineering 2019, 1, 16.
- Atarod S, Norden J, Bibby LA, Janin A, Ratajczak P, Lendrem C, Pearce KF, Wang XN, O'Reilly S, Van Laar JM, Collin M, Dickinson AM, Crossland RE. Differential MicroRNA Expression Levels in Cutaneous Acute Graft-versus-Host Disease. Frontiers in Immunology 2018, 9, 1485.
- Reis M, McDonald D, Nicholson L, Godthardt K, Knobel S, Dickinson AM, Filby A, Wang X-N. Global phenotypic characterisation of human platelet lysate expanded MSCs by high-throughput flow cytometry. Scientific Reports 2018, 8(1), 3907.
- Lim H, Lim S, Tan C, Thiam C, Goh C, Carbajo D, Chew S, See P, Chakarov S, Wang X, Lim L, Johnson L, Lum J, Fong C, Bongso A, Biswa A, Goh C, Evrard M, Yeo K, Basu R, Wang J, Tan Y, Jain R, Tikoo S, Choong C, Weninge W, Poidinger M, Stanley R, Collin M, Tan N, Ng L, Jackson D, Ginhoux F, Angeli V. Hyaluronan Receptor LYVE-1-Expressing Macrophages Maintain Arterial Tone through Hyaluronan-Mediated Regulation of Smooth Muscle Cell Collagen. Immunity 2018, 49(2), 326-341.
- Reis M, Mavin E, Nicholson L, Green K, Dickinson A, Wang X. Mesenchymal stromal cell-derived extracellular vesicles attenuate dendritic cell maturation and function. Frontiers in Immunology 2018, 9, 2538.
- Dickinson A, Nong Wang X, Ahmed S. An In Vitro Human Skin Test for Assessing Adverse Immune Reactions and Sensitization Potential. In: Alternatives for Dermal Toxicity Testing. Springer International Publishing, 2017, pp.437-448.
- McGovern N, Shin A, Low G, Low D, Duan K, Yao LJ, Msallam R, Low I, Shadan NB, Sumatoh HR, Soon E, Lum J, Mok E, Hubert S, See P, Kunxiang EH, Lee YH, Janela B, Choolani M, Mattar CNZ, Fan Y, Lim TKH, Hong DK, Tan KK, Tam JKC, Schuster C, Elbe-Bürger A, Wang XN, Bigley V, Collin M, Haniffa M, Schlitzer A, Poidinger M, Albani S, Larbi A, Newell EW, Chan JKY, Ginhoux F. Human fetal dendritic cells promote prenatal T-cell immune suppression through arginase-2. Nature 2017, 546, 662-666.
- Mavin E, Nicholson L, Amed RS, Gao F, Dickinson A, Wang Xiao-nong. Human regulatory T cells mediate transcriptional modulation of dendritic cell function. The Journal of Immunology 2017, 198(1), 138-146.
- Ghimire S, Weber D, Mavin E, Wang XN, Dickinson AM, Holler E. Pathophysiology of GvHD and other HSCT-related major complications. Frontiers in Immunology 2017, 8, 79.
- Ahmed SS, Wang XN, Fielding M, Kerry A, Dickinson I, Munuswamy R, Kimber I, Dickinson AM. An in vitro human skin test for assessing sensitization potential. Journal of Applied Toxicology 2016, 36(5), 669-684.
- Qesari M, Richter A, Ogonek J, Mischak-Weissinger E, Wang X, Dickinson A. Cytomegalovirus-Specific T Cells Isolated by IFN-[gamma] Secretion Assay Do Not Induce Significant Graft-Versus-Host Reactions In Vitro. Transplantation 2016, 100(11), 2352-2361.
- Ahmed SS, Wang XN, Norden J, Pearce K, El-Gezawy E, Atarod S, Hromadnikova I, Collin M, Holler E, Dickinson AM. Identification and validation of biomarkers associated with acute and chronic graft versus host disease [Corrigendum]. Bone Marrow Transplantation 2016, 51(6), 890.
- Beattie B, Cole D, Nicholson L, Leech S, Taylor A, Robson H, Guest J, Wang XN, Gennery AR. Limited thymic recovery after extracorporeal photopheresis in a low-body-weight patient with acute graft-versus-host disease of the skin. Journal of Allergy and Clinical Immunology 2016, 137(6), 1890-1893.
- Al-Shaibani M, Wang X, Lovat P, Dickinson A. Mesenchymal stem cells promote wound healing via differentiation into epidermal keratinocyte-like cells. In: BSID Annual Meeting 2016. 2016, Dundee, Scotland: Wiley-Blackwell.
- Atarod S, Ahmed MA, Lendrem C, Pearce KP, Cope W, Norden J, Wang X, Collin M, Dickinson AM. MiR-146a and miR-155 expression levels in acute graft-versus-host disease incidence. Frontiers in Immunology (Alloimmunity and Transplantation) 2016, 7, 56.
- Reis M, Ogonek J, Qesari M, Borges NM, Nicholson L, Preussner L, Dickinson AM, Wang XN, Weissinger EM, Richter A. Recent Developments in Cellular immunotherapy for HSCT-Associated Complications. Frontiers in Immunology 2016, 7, 500.
- Mavin E, Nicholson L, Dickinson A, Wang XN. Regulatory T cells modulate dendritic cell maturation and function at a transcriptional level. In: ICI 2016 International Congress of Immunology. 2016, Melbourne, Australia: Wiley-VCH Verlag.
- Muller S, Tang J, Nicholson L, Nong-Wang X, De Havilland JR, Dickinson A. CD271 enrichment of BM-derived MSCs enhances their osteogenic potency. In: 21st ISCT Annual Meeting. 2015, Las Vegas, Nevada: Elsevier Ltd.
- Qesari M, Richter A, Wang XN, Dickinson AM. Cytomegalovirus specific T cells do not allo-react in the human-in vitro skin explant model. In: 41st Annual Meeting of the European Society for Blood and Marrow Transplantation. 2015, Istanbul, Turkey: Nature Publishing Group.
- Al-Shaibani MBH, Wang XN, Lovat PE, Dickinson AM. Deciphering the Role of Mesenchymal Stem Cells Paracrine in Wound Closure Acceleration. In: 41st Annual Meeting of the European Society for Blood and Marrow Transplantation. 2015, Istanbul, Turkey: Nature Publishing Group.
- Nicholson L, Collin M, Dickinson A, Wang XN. Developing an in vitro predictive test for steroid response in graft versus host disease. In: 41st Annual Meeting of the European Society for Blood and Bone Marrow Transplantation (EBMT). 2015, Istanbul, Turkey: Nature Publishing Group.
- Nicholson L, Collin M, Dickinson A, Wang XN. Developing an in vitro predictive test for steroid response in graft versus host disease. In: 41st Annual Meeting of the European Society for Blood and Marrow Transplantation. 2015, Istanbul, Turkey: Nature Publishing Group.
- Atarod S, Pearce K, Norden J, Lendrem C, Crossland R, Wang XN, Sviland L, Janin A, Collin M, Dickinson A. Differential microRNA expressions in cutaneous acute graft-versus-host disease. In: 41st Annual Meeting of the European Society for Blood and Marrow Transplantation. 2015, Istanbul, Turkey: Nature Publishing Group.
- Atarod S, Turner B, Pearce KF, Ahmed SS, Norden J, Bogunia-Kubik K, Wang XN, Collin M, Dickinson AM. Elevated level of HSPA1L mRNA correlates with graft-versus-host disease. Transplant Immunology 2015, 32(3), 188-194.
- Cuthbert RJ, Giannoudis PV, Wang XN, Nicholson L, Pawson D, Lubenko A, Tan HB, Dickinson A, McGonagle D, Jones E. Examining the Feasibility of Clinical Grade CD271+ Enrichment of Mesenchymal Stromal Cells for Bone Regeneration. PLoS One 2015.
- Nicholson L, Mavin E, Minto L, Irving J, Dickinson A, Wang XN. Gene Expression Profiling Implicates Attenuation of NFkB Signalling By Regulatory T Cells in Modulating Dendritic Cell Function. In: 57th Annual Meeting and Exposition of the American Society of Hematology (ASH). 2015, Orlando, FL, USA: American Society of Hematology.
- Nicholson L, Mavin E, Minto L, Irving J, Dickinson A, Wang XN. Gene Expression Profiling Implicates Attenuation of NFkB Signalling By Regulatory T Cells in Modulating Dendritic Cell Function. In: 57th ASH Annual Meeting 2015. 2015, Orlando, USA: American Society of Hematology.
- Reis M, Nicholson L, Dickinson A, Wang XN. Human Platelet Lysate Promotes Proliferation and Maintains Immunomodulatory Capacity of Mesenchymal Stromal Cells. In: 41st Annual Meeting of the European Society for Blood and Marrow Transplantation (EBMT). 2015, Istanbul, Turkey: Nature Publishing Group.
- Reis MSCD, Nicholson L, Dickinson A, Wang XN. Human Platelet Lysate Promotes Proliferation and Maintains Immunomodulatory Capacity of Mesenchymal Stromal Cells. In: 41st Annual Meeting of the European Society for Blood and Marrow Transplantation. 2015, Istanbul, Turkey: Nature Publishing Group.
- Ahmed SS, Wang XN, Norden J, Pearce K, El-Gezawy E, Atarod S, Hromadnikova I, Collin M, Holler E, Dickinson AM. Identification and validation of biomarkers associated with acute and chronic graft versus host disease. Bone Marrow Transplantation 2015, 50(12), 1563-1571.
- Atarod S, Smith H, Dickinson A, Wang X. MicroRNA levels quantified in whole blood varies from PBMCs. F1000Research 2015, 3, 183.
- Mavin E, Nicholson L, Ahmed R, Dickinson A, Wang XN. Treg treated dendritic cells are defective in initiating cutaneous GVH reactions. In: 41st Annual Meeting of the European Society for Blood and Marrow Transplantation. 2015, Istanbul, Turkey: Nature Publishing Group.
- Wang XN, McGovern N, Gunawan M, Richardson C, Windebank M, Siah TW, Lim HW, Fink K, Li J, Ng LG, Ginhoux F, Angeli V, Collin M, Haniffa M. A Three Dimensional Atlas of Human Dermal Leukocytes, Lymphatics and Blood Vessels. Journal of Investigative Dermatology 2014, 134, 965-974.
- Aljefri K, Wang XN, Husain A, Bacon C, Long A, Pagan S, Collin M, Haniffa M. Factor XIIIa identifies macrophages and cells of mesenchymal origin in the human skin. In: British Society of Investigative Dermatology Annual Meeting. 2014, Newcastle upon Tyne: Wiley-Blackwell Publishing Ltd.
- McGovern N, Schlitzer A, Gunawan M, Jardine L, Shin A, Poyner E, Green K, Dickinson R, Wang XN, Low D, Best K, Covins S, Milne P, Pagan S, Aljefri K, Windebank M, Saavedra DM, Larbi A, Wasan PS, Duan K, Poidinger M, Bigley V, Ginhoux F, Collin M, Haniffa M. Human Dermal CD14+ Cells Are a Transient Population of Monocyte-Derived Macrophages. Immunity 2014, 41(3), 465-477.
- McGovern N, Schlitzer A, Gunawan M, Jardine L, Shin A, Poyner E, Green K, Dickinson R, Wang XN, Low D, Best K, Covins S, Milne P, Pagan S, Aljefri K, Windebank M, Miranda-Saavedra D, Wasan P, Kaibo D, Poidinger M, Bigley V, Ginhoux F, Collin M, Haniffa M. Human tissue mononuclear phagocyte system revisited. In: British Society for Immunology Annual Congress. 2014, Brighton, UK: Wiley-Blackwell Publishing Ltd.
- Wang XN, McGovern N, Gunawan M, Richardson C, Windebank M, Siah TW, Lim HY, Fink K, Li JY, Ng L, Ginhoux F, Angeli V, Collin M, Haniffa M. Microanatomical dissection of the human dermis: the three-dimensional relationship between leucocytes, lymphatics and blood vessels. In: British Society of Investigative Dermatology Annual Meeting. 2014, Newcastle upon Tyne: Wiley-Blackwell.
- Haggerty JM, Wang XN, Dickinson A, O'Malley CJ, Martin EB. Segmentation of epidermal tissue with histopathological damage in images of haematoxylin and eosin stained human skin. BMC Medical Imaging 2014, 14, 7.
- Emily M, Nicholson L, Ahmed R, Collin M, Dickinson A, Wang XN. Treg Induced Impairment of DC Function and Its Impact on GvH Reactions. In: 56th ASH Annual Meeting and Exposition. 2014, San Francisco, CA, USA: American Society of Hematology.
- Mavin E, Dickinson A, Wang XN. Do Cryopreserved Regulatory T Cells Retain Their Suppressive Potency?. Transplantation 2013, 95(11), e68-e70.
- Holtick U, Wang XN, Marshall SR, Scheid C, von Bergwelt-Baildon M, Dickinson AM. Immature DC Isolated After Co-Culture with PUVA-Treated Peripheral Blood Mononuclear Cells Downregulate Graft-Versus-Host Reactions in the Human Skin Explant Model. Current Stem Cell Research & Therapy 2013, 8(4), 324-332.
- Jardine L, Hambleton S, Bigley V, Pagan S, Wang X-N, Collin M. Sensitizing primary acute lymphoblastic leukemia to natural killer cell recognition by induction of NKG2D ligands. Leukemia and Lymphoma 2013, 54(1), 167-173.
- Mavin ER, Dickinson AM, Wang XN. The use of third party Treg to ameliorate graft-versus-host reactions. In: 39th Annual Meeting of the European Group for Blood and Marrow. 2013, London, UK: Nature Publishing Group.
- Mavin E, Atarod S, Collin M, Dickinson A, Wang X. An association between skin homing T-cells and graft-versus-host disease. In: 38th Annual Meeting of the European Group for Blood and Marrow Transplantation (EBMT). 2012, Geneva, Switzerland: Nature Publishing Group.
- Mavin E, Dickinson AM, Wang XN. Feasibility of using regulatory T cells as an 'off the shelf' cellular reagent. In: European Congress of Immunology. 2012, Glasgow, UK: Wiley-Blackwell.
- Haniffa M, Shin A, Bigley V, McGovern N, Teo P, See P, Wasan PS, Wang XN, Malinarich F, Malleret B, Larbi A, Tan P, Zhao H, Poidinger M, Pagan S, Cookson S, Dickinson R, Dimmick I, Jarrett RF, Renia L, Tam J, Song C, Connolly J, Chan JK, Gehring A, Bertoletti A, Collin M, Ginhoux F. Human Tissues Contain CD141hi Cross-Presenting Dendritic Cells with Functional Homology to Mouse CD103+ Nonlymphoid Dendritic Cells. Immunity 2012, 37(1), 60-73.
- Haniffa M, Shin A, Bigley V, Teo P, See P, Wasan P, McGovern N, Wang XN, Malinarich F, Malleret B, Larbi A, Poidinger M, Jarrett R, Connolly J, Chan J, Gehring A, Bertoletti A, Collin M, Ginhoux F. Identification of a novel cross-presenting migratory dendritic cell in the human skin: the key cell for rational vaccine strategies. In: 92nd Annual Meeting of the British Association of Dermatologists. 2012, Birmingham, UK: Wiley-Blackwell Publishing Ltd.
- Haniffa M, Shin A, Bigley V, Teo P, See P, Wasan P, McGovern N, Wang XN, Malinarich F, Malleret B, Poidinger M, Gehring A, Bertoletti A, Collin M, Ginhoux F. Identification of the human cross-presenting migratory dendritic cell. In: Meeting of the British Society for Investigative Dermatology. 2012, Exeter, UK: Wiley-Blackwell Publishing Ltd.
- Holtick U, Wang XN, Marshall SR, Scheid C, von Bergwelt-Baildon M, Dickinson AM. In Vitro PUVA Treatment Preferentially Induces Apoptosis in Alloactivated T Cells. Transplantation 2012, 94(5), E31-E34.
- Stocki P, Wang XN, Dickinson AM. Inducible Heat Shock Protein 70 Reduces T cell Responses and Stimulatory Capacity of Monocyte-derived Dendritic Cells. Journal of Biological Chemistry 2012, 287(15), 12387-12394.
- Madhra M, Mavin E, Grainger A, Barge D, Wang XN, Walter J, Matthew D, Notarangelo LD, Gennery A. Regulatory T cell subsets, T cell receptor repertoire, and autoantibodies in RAG1-deficient Omenn syndrome. In: 15th Biennial Meeting European Society for Immunodeficiency (ESID). 2012, Florence, Italy: Springer.
- Mavin E, Ahmed SS, O'Boyle G, Turner B, Douglass S, Collin M, Ali S, Dickinson A, Wang X-N. Regulatory T Cells Inhibit CD8+ T-Cell Tissue Invasion in Human Skin Graft-Versus-Host Reactions. Transplantation 2012, 94(5), 456-464.
- Haniffa M, Shin A, Bigley V, McGovern N, Wang XN, Teo P, Sng D, Won JM, Marinarich FG, Malleret B, See P, Larbi A, Zhou H, Poidinger M, Pagan S, Cookson S, Dickinson R, Connolly J, Gehring A, Bertoletti A, Collin M, Ginhoux F. CD141(+) human migratory dendritic cells are homologous to murine CD103+dendritic cells and excel at exogenous antigen cross-presentation. In: Immunology: Annual Congress of the British Society for Immunology. 2011, Liverpool, UK: Wiley-Blackwell Publishing Ltd.
- Atarod S, Norden J, Kuzyk-Czucha A, Bogunia-Kubik K, Turner B, Ambler L, Wang XN, Collin M, Dickinson AM. Correlation of HSPA1Lexpression with the development of graft-versus-host disease. In: Bone Marrow Transplantation: 37th European Group for Bone and Marrow Transplantation. 2011, Paris, France: Nature Publishing Group.
- Bigley V, Haniffa M, Doulatov S, Wang XN, Dickinson R, McGovern N, Spence L, Pagan S, Carey C, Dimmick I, Chua I, Wallis J, Lordan J, Morgan C, Kumararatne DS, Doffinger R, van der Burg M, van Dongen J, Cant A, Jackson G, Dick JE, Hambleton S, Collin M. Dendritic cell, monocyte, B and NK lymphoid deficiency: a novel but potentially fatal haematological disorder curable with haematopoietic stem cell transplantation. In: Bone Marrow Transplantation: 37th European Group for Bone and Marrow Transplantation. 2011, Paris, France: Nature Publishing Group.
- Dickinson RE, Griffin H, Bigley V, Reynard LN, Hussain R, Haniffa M, Lakey JH, Rahman T, Wang XN, McGovern N, Pagan S, Cookson S, McDonald D, Chua I, Wallis J, Cant A, Wright M, Keavney B, Chinnery PF, Loughlin J, Hambleton S, Santibanez-Koref M, Collin M. Exome sequencing identifies GATA-2 mutation as the cause of dendritic cell, monocyte, B and NK lymphoid deficiency. Blood 2011, 118(10), 2656-2658.
- Novota P, Zinocker S, Norden J, Wang XN, Sviland L, Opitz L, Salinas-Riester G, Rolstad B, Dickinson AM, Walter L, Dressel R. Expression profiling of major histocompatibility and natural killer complex genes reveals new candidates for controlling risk of graft versus host disease. In: Tissue Antigens: 25th Conference on European Immunogenetics and Histocompatibility. 2011, Prague, Czech Republic: Wiley-Blackwell Publishing, Inc.
- Stocki P, Wang XN, Morris NJ, Dickinson AM. HSP70 Natively and Specifically Associates with an N-terminal Dermcidin-derived Peptide That Contains an HLA-A*03 Antigenic Epitope. Journal of Biological Chemistry 2011, 286(14), 12803-12811.
- McGovern N, Bigley V, Allen C, Haniffa M, Wang XN, Dickinson R, Pagan S, Windebank K, McClain K, Ginhoux F, Merad M, Collin M. Human Langerin plus dendritic cells are independent of epithelial Langerhans cells; a novel perspective on Langerhans cell histiocytosis. In: Immunology: Annual Congress of the British Society for Immunology. 2011, Liverpool, UK: Wiley-Blackwell Publishing Ltd.
- Sturgess K, Slatter M, Bigley V, Haniffa M, Wang XN, Dickinson R, McGovern N, Jardine L, Pagan S, Chua I, Wallis J, Lordan J, Morgan C, Cant A, Gennery A, Edmondson R, Bacon C, Black F, Kirkham N, Jackson GH, Hambleton S, Collin MP. Reduced Intensity Hematopoietic Stem Cell Transplant Rescues Immune Function and Corrects Pulmonary Alveolar Proteinosis in DCML Deficiency/GATA 2 Mutation. In: Blood: 53rd Annual Meeting and Exposition of the American Society of Hematology (ASH). 2011, San Diego, California, USA: American Society of Hematology.
- Mavin ER, Dickinson AM, Wang XN. Regulatory T cell suppressive functions are not affected by cryo-preservation. In: Immunology: Annual Congress of the British Society for Immunology. 2011, Liverpool, UK: Wiley-Blackwell Publishing Ltd.
- Bigley V, Haniffa M, Doulatov S, Wang XN, Dickinson R, McGovern N, Jardine L, Pagan S, Dimmick I, Chua I, Wallis J, Lordan J, Morgan C, Kumararatne DS, Doffinger R, van der Burg M, van Dongen J, Cant A, Dick JE, Hambleton S, Collin M. The human syndrome of dendritic cell, monocyte, B and NK lymphoid deficiency. Journal of Experimental Medicine 2011, 208(2), 227-234.
- Ruffin N, Ahmed SS, Osorio LM, Wang XN, Jackson GH, Collin MP, Ekre HP, Chiodi F, Dickinson AM. The Involvement of Epithelial Fas in a Human Model of Graft Versus Host Disease. Transplantation 2011, 91(9), 946-951.
- Kuzyk A, Bogunta-Kubik K, Jackson G, Cullin M, Wang XN, Dickinson A. HSP70-hom gene polymorphism as a risk factor of graft-versus-host disease. In: 2nd European Congress of Immunology (ECI). 2009, Berlin, Germany: Medimond SRL.
- Collin M, Munster D, Clark G, Wang XN, Dickinson A, Hart D. Antibody-mediated suppression of allogeneic responses by targeting the tissue dendritic cell: A potential role for CMRF-44 where alemtuzumab fails. In: Blood: 45th Annual Meeting of the American Society of Hematology. 2003, San Diego, California, USA: American Society of Hematology.
- Dickinson AM, Stark G, Cullup H, Jarvis M, Wang XN, Middleton PG. Cytokine Gene Polymorphism in Transplantation. Hematopoietic Stem Cells Research and Clinical Applications 2003, European School of Haematology.
- Jarvis M, Marzolini MAV, Wang XN, Sviland L, Dickinson AM. Heat shock protein 70: Correlation of expression with degree of graft-versus-host response and clinical GVHD: Quantitative assessment using laser scanning confocal microscopy. In: Genes and Immunity: 17th European Histocompatability Conference. 2003, Baden, Germany: Nature Publishing Group.
- Cullup H, Wang XN, Dickinson AM. HLA-matcing influences the production of the IL-1 family of cytokines in an alloimmune response. In: Genes and Immunity: 17th European Histocompatability Conference. 2003, Baden, Germany: Nature Publishing Group.
- Dickinson AM, Wang XN, Sviland L, Cullup H. Neutralisation of IL-1 receptor antagonist is associated with increased graft versus host damage demonstrated in a human in vitro modified model of graft versus host disease. In: Blood: 45th Annual Meeting of the American Society of Hematology. 2003, San Diego, California, USA: American Society of Hematology.
- Cullup H, Wang XN, Dickinson AM. The level of IL-1B and IL-1RA in MLR supernatants is associated with the incidence of aGVHD following HLA-matched sibling BMT. In: Genes and Immunity: 17th European Histocompatability Conference. 2003, Baden, Germany: Nature Publishing Group.
- Dickinson A, Wang XN. Are the functional assays useful in predicting graft-versus-host disease in HLA-matched sibling bone marrow transplantation?. Transplantation 2001, 72(6), 1168-1168.
- Sviland L, Hromadnikova I, Sedlacek P, Cermakova M, Stechova K, Holler E, Eissner G, Schulz U, Kolb HJ, Jackson G, Wang XN, Dickinson AM. Histological correlation between different centers using the skin explant model to predict graft-versus-host disease following bone marrow transplantation. Human Immunology 2001, 62(11), 1277-1281.
- Wang XN, Dickinson AM, Sviland L, Vyth-Dreese FA, Jackson GH, Schumacher TNM, Haanen JBAG, Mutis T, Goulmy E. Minor histocompatibility antigen specific CTLs and in situ skin graft versus host reactions. In: Blood: 53rd Annual Meeting and Exposition of the American Society of Hematology (ASH). 2001, Orlando, Florida, USA: American Society of Hematology.
- Cohen SBA, Wang XN, Dickinson A. Can cord blood cells support the cytokine storm in GvHD?. Cytokine and Growth Factor Reviews 2000, 11(3), 185-197.
- Wilcox AEC, Wang XN, Oliver K, Dickinson AM, Jackson GH. Increased sensitivity of the cord blood alloresponse to cyclosporin. In: Forty-first Annual Meeting of the American Society of Hematology. 1999, Oakland, California, USA: American Society of Hematology.