NES8802 : Drug Metabolism and Toxicology
- Offered for Year: 2024/25
- Available to incoming Study Abroad and Exchange students
- Module Leader(s): Professor Mike Waring
- Owning School: Natural and Environmental Sciences
- Teaching Location: Newcastle City Campus
Semesters
Your programme is made up of credits, the total differs on programme to programme.
| Semester 1 Credit Value: | 10 |
| ECTS Credits: | 5.0 |
| European Credit Transfer System | |
Aims
To introduce the principles of pharmacokinetics, drug metabolism and toxicology; to understand the importance of optimising these parameters in drug discovery; to understand the chemical basis of drug metabolism and its importance in drug discovery; to equip students with a knowledge and understanding of the mechanism of toxicity of drug molecules and other the environmental toxins
Outline Of Syllabus
Pharmacokinetics and drug metabolism (Professor M Waring)
Principles of pharmacokinetics
Processes and mechanisms of drug metabolism
Selected case studies in drug metabolism
Toxicology (Dr Kate Madden)
Principles of Toxicology and toxicokinetics
Critical toxicological issues for drug discovery
Allergens and reactive metabolites
Ion channels – hERG and acetyl choline signalling
Carcinogenesis
Teaching Methods
Teaching Activities
| Category | Activity | Number | Length | Student Hours | Comment |
|---|---|---|---|---|---|
| Scheduled Learning And Teaching Activities | Lecture | 12 | 1:00 | 12:00 | PiP lectures |
| Guided Independent Study | Assessment preparation and completion | 1 | 1:30 | 1:30 | End of Semester examination |
| Guided Independent Study | Assessment preparation and completion | 1 | 20:00 | 20:00 | Revision for end of Semester 1 examination |
| Guided Independent Study | Assessment preparation and completion | 2 | 10:00 | 20:00 | Online assessments - Structured literature exercise: case study and literature reading |
| Guided Independent Study | Assessment preparation and completion | 12 | 1:00 | 12:00 | Online materials via Canvas |
| Guided Independent Study | Independent study | 1 | 34:30 | 34:30 | Independent study |
| Total | 100:00 |
Teaching Rationale And Relationship
Students acquire knowledge and understanding through online lecture content and live module talks. Problem-solving skills are practiced in module talks and in private study.
Assessment Methods
The format of resits will be determined by the Board of Examiners
Exams
| Description | Length | Semester | When Set | Percentage | Comment |
|---|---|---|---|---|---|
| Written Examination | 90 | 1 | A | 50 | PiP exam |
Other Assessment
| Description | Semester | When Set | Percentage | Comment |
|---|---|---|---|---|
| Computer assessment | 1 | M | 50 | Online assessment |
Formative Assessments
Formative Assessment is an assessment which develops your skills in being assessed, allows for you to receive feedback, and prepares you for being assessed. However, it does not count to your final mark.
| Description | Semester | When Set | Comment |
|---|---|---|---|
| Prob solv exercises | 1 | M | Online canvas quiz |
Assessment Rationale And Relationship
The exam will test the student’s knowledge and understanding of the coursework as well as information literacy and presentation skills.
Formative assessment to allow student to test their understanding of module so far.
Study Abroad students may request to take their exam before the semester 1 exam period, in which case the format of the paper may differ from that shown in the MOF. Study Abroad students should contact the school to discuss this.
Reading Lists
Timetable
- Timetable Website: www.ncl.ac.uk/timetable/
- NES8802's Timetable