Outputs
The Newcastle Research Tissue Biobank has supported a range of research outputs.
About
Below you’ll find information on resultant outputs and follow on funding acquired by projects conducted through the Newcastle Research Tissue Biobank.
We request that the Biobank is recognised and acknowledged in any outputs that result from using samples provided, including publications, presentations and follow on funding, as we rely on proof of impact to continue to support researchers with the resources that they need. Although the facility operates on a cost recovery system, the full economic cost is not passed on to end users.
To acknowledge the Biobank in publications or presentations, please use the following phrasing (or similar):
Samples/Tissue for this study was provided by the Newcastle Research Tissue Biobank which is supported by the Newcastle upon Tyne NHS Foundation Trust and Newcastle University.
If you would like information on costings or advice for a grant proposal, please contact the Biobank to arrange a meeting.
Publications since 2020
2024
Ghantous, A., Nusslé, S.G., Nassar, F.J. et al. Epigenome-wide analysis across the development span of pediatric acute lymphoblastic leukemia: backtracking to birth. Mol Cancer 23, 238 (2024). https://doi.org/10.1186/s12943-024-02118-4
Hipps, D., Pyle, A., Porter, A.L.R. et al. Variant load of mitochondrial DNA in single human mesenchymal stem cells. Sci Rep 14, 20989 (2024). https://doi.org/10.1038/s41598-024-71822-4
2022
Hipps, D., Dobson, P. F., Warren, C., et al. Detecting respiratory chain defects in osteoblasts from osteoarthritic patients using imaging mass cytometry. Bone 158 (2022) https://doi.org/10.1016/j.bone.2022.116371
Klaassen, I., Avery, P., Schlingemann, R.O. et al. Vitreous protein networks around ANG2 and VEGF in proliferative diabetic retinopathy and the differential effects of aflibercept versus bevacizumab pre-treatment. Sci Rep 12, 21062 (2022). https://doi.org/10.1038/s41598-022-25216-z
2021
Lefevere, E., Van Hove, I., Sergeys, J. et al. PDGF as an Important Initiator for Neurite Outgrowth Associated with Fibrovascular Membranes in Proliferative Diabetic Retinopathy. Curr Eye Res 47 (2), 277–286. (2021). https://doi.org/10.1080/02713683.2021.1966479
Sudhindar, P.D., Wainwright, D., Saha, S., et al. HCV Activates Somatic L1 Retrotransposition—A Potential Hepatocarcinogenesis Pathway. Cancers 13, 5079 (2021) https://doi.org/10.3390/cancers13205079
Barrow, T.M., Nakjang, S., Lafta, F. et al. Epigenome-wide analysis reveals functional modulators of drug sensitivity and post-treatment survival in chronic lymphocytic leukaemia. Br J Cancer 124, 474–483 (2021). https://doi.org/10.1038/s41416-020-01117-8
Publications until 2020
2020
Friedrich, J,. Steel, D.H.W., Schlingemann, R.O., et al. microRNA Expression Profile in the Vitreous of Proliferative Diabetic Retinopathy Patients and Differences from Patients Treated with Anti-VEGF Therapy. Trans. Vis. Sci. Tech. 9, (6) 16 (2021). https://doi.org/10.1167/tvst.9.6.16
Szoltysek, K., Ciardullo, C., Zhou, P., et al. DAP Kinase-Related Apoptosis-Inducing Protein Kinase 2 (DRAK2) Is a Key Regulator and Molecular Marker in Chronic Lymphocytic Leukemia. Int. J. Mol. Sci. 21, 7663. (2020) https://doi.org/10.3390/ijms21207663
2019
Paish, H.L., Baldock, T.E., Gillespie, C.S., et al. Chronic, Active Inflammation in Patients With Failed Total Knee Replacements Undergoing Revision Surgery. J Orthop Res., 37, 2316-2324. (2019). https://doi.org/10.1002/jor.24398
Gentles, L., Goranov, B., Matheson, E., et al. Exploring the Frequency of Homologous Recombination DNA Repair Dysfunction in Multiple Cancer Types. Cancers, 11, 354. (2019) https://doi.org/10.3390/cancers11030354
2018
Franklin M, Gentles L, Matheson E, et al. Characterization and drug sensitivity of a novel human ovarian clear cell carcinoma cell line genomically and phenotypically similar to the original tumor. Cancer Med. 7: 4744–4754. (2018) https://doi.org/10.1002/cam4.1724
2017
Klaassen I, de Vries EW, Vogels IMC, et al. Identification of proteins associated with clinical and pathological features of proliferative diabetic retinopathy in vitreous and fibrovascular membranes. PLOS ONE 12 (11): e0187304. (2017) https://doi.org/10.1371/journal.pone.0187304
Paish, H.L., Kalson, N.S., Smith, G.R., et al. Fibroblasts Promote Inflammation and Pain via IL-1α Induction of the Monocyte Chemoattractant Chemokine (C-C Motif) Ligand 2. Am J Pathol. 188, 3, (2018) https://doi.org/10.1016/j.ajpath.2017.11.007
Steel, D.H.W., Dinah, C., White, K. and Avery, P.J., The relationship between a dissociated optic nerve fibre layer appearance after macular hole surgery and Muller cell debris on peeled internal limiting membrane. Acta Ophthalmol, 95, 153-157. (2017) https://doi.org/10.1111/aos.13195
2015
Steel, D.H.W., Sandinha, M.T., White, K.,; The Plane of Vitreoretinal Separation and Results of Vitrectomy Surgery in Patients Given Ocriplasmin for Idiopathic Macular Hole. Invest. Ophthalmol. Vis. Sci. 56 (6):4038-4044. (2015) https://doi.org/10.1167/iovs.15-16409
Abdul, N., Dixon, D., Walker, A. et al. Fibrosis is a common outcome following total knee arthroplasty. Sci Rep 5, 16469 (2015). https://doi.org/10.1038/srep16469
Dixon, D., Coates, J., del Carpio Pons, A. et al. A potential mode of action for Anakinra in patients with arthrofibrosis following total knee arthroplasty. Sci Rep 5, 16466 (2015). https://doi.org/10.1038/srep16466
2014
O′Donnell RL, McCormick A, Mukhopadhyay A, et al. The Use of Ovarian Cancer Cells from Patients Undergoing Surgery to Generate Primary Cultures Capable of Undergoing Functional Analysis. PLOS ONE 9 (3): e90604. (2014) https://doi.org/10.1371/journal.pone.0090604
Patterson, M., Sutton, R., Forrest, I. et al. Assessing the function of homologous recombination DNA repair in malignant pleural effusion (MPE) samples. Br J Cancer 111, 94–100 (2014). https://doi.org/10.1038/bjc.2014.261
