Staff Profile

Introduction

I am a member of the Translational and Clinical Research Institute at the Campus for Ageing and Vitality where I am Scientific Director of the Newcastle Brain Tissue Resource and also a member of the Dementia and Neurodegenerative Diseases Group as part of the Mental Health, Dementia and Neurodegeneration theme.

Roles and Responsibilities

Designated Individual, Newcastle University Human Tissue Authority Research Licence

Co-Chair, Translational and Clinical Research Institute GM Safety Committee

Food Standards Agency Committee on Toxicity, Member (2024-date)

Expert Committee on Pesticides (2016-2022)

Advisory Committee on Pesticides, Member (2012-2015)

Member of the Advisory Committee on Pesticides Medical and Toxicology Panel (2012-2015)

Chair, Peer Review Panel, Parkinson's UK and MS Society Brain Bank, Imperial College, London (2012-2022)

Qualifications 

BSc(Hons)

PhD

Previous Positions

Medical Research Council Staff Scientist, MRC Neurochemical Pathology Unit, 1987-1999

Medical Research Council External Staff Scientist, MRC/University of Newcastle Centre Development in Clinical Brain Ageing, 2000-2005

Visiting Researcher, National Institutes of Genome Research/National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland USA, 2004

Health Protection Agency, Scientist, Chemical Hazards and Poisons Division, 2005-2006 

Memberships

British Toxicology Society

Areas of expertise: Neuroscience, Neurotoxicology, Neurodegeneration, Alzheimer’s disease, Parkinson’s Disease, Dementia with Lewy Bodies

ORCID record at http://orcid.org/0000-0002-3749-0993

Google Scholar: Click here. 

My research focuses on the mechanisms that cause specific symptoms experienced by patients with different neurodegenerative disorders such as Alzheimer's disease, Dementia with Lewy Bodies and Parkinson's disease. We use brain tissue from well characterised donors and a variety of experimental approaches to investigate symptoms such as visual hallucinations, depression, anxiety, and memory problems. Our approach involves quantitative neuropathological investigation to determine if specific cell loss or pathology underpins symptoms and also molecular approaches including RNAseq, protein methods and genetic analysis to build an understanding of the different disorders to identify specific treatments.

We develop stem cell models of different neurodegenerative disorders including Dementia with Lewy Bodies, Alzheimer's disease, Progressive Supranuclear Palsy. These cell lines are derived from donors entering our Newcastle Brain Tissue Resource through the Brains for Dementia Research initiative (https://bdr.alzheimersresearchuk.org/researchers/what-bdr-offers/stem-cells/) and provide an accessible iPSC model for use by the research community.

My research also looks at how specific toxins might affect the nervous system and how they might contribute to late onset neurodegeneration. We are interested in how environmental chemicals, man made or natural, contribute to specific disorders such as Parkinson's disease. Understanding the mode of action of these chemicals may provide us with evidence of how the different neurodegenerative disorders occur.

We have a specific interest in the role of carbon monoxide as a contributor to long term motor and memory problems. Carbon monoxide is a major preventable cause of illness globally and can lead to chronic health problems following exposure even at low levels. We aim to identify new ways of detecting if people are exposed to carbon monoxide, and also to find ways to understand how carbon monoxide causes certain symptoms in exposed people.

Funding

"Molecular Mechanisms Underlying Visual Hallucinations in Dementia with Lewy Bodies" funding from the Alzheimer's Society June 2013-December 2015.

"Utility of Mitochondrial Complex IV Analysis as a Biomarker of Carbon Monoxide Exposure" funding from the Gas Safety Trust June 2016-March 2017

"Identification of protein biomarkers in peripheral blood lymphocytes following carbon monoxide exposure" funding from the Gas Safety Trust April 2020- March 2024. 

"NIHR Newcastle BioResource" funding from the National Institutes of Health Research, April 2018-March 2024.

"Developing Biochemical Methods to detect Dementia with Lewy bodies" funded by the Lewy Body Society, January 2019-December 2022.

"Brains for Dementia Research Stem Cell and Fibroblast Bank" funded by Alzheimer's Society, April 2020-September 2024.

Undergraduate Teaching

Biomedical Sciences BMS3013 Diseases of the Nervous System

Postgraduate Teaching

MRCPsych Course

MRes in Medical and Molecular Biosciences Research Skills and Principles for the Biosciences MMB8100

MRes in Medical and Molecular Biosciences, Genetic Basis of Common (Complex) Disease MMB8014

MRes in Medical and Molecular Biosciences, Toxicology MMB8032

• Articles

  • Brooks J, Everett J, Hill E, Billimoria K, Morris CM, Sadler PJ, Telling N, Collingwood JF. Nanoscale synchrotron x-ray analysis of intranuclear iron in melanised neurons of Parkinson's substantia nigra. Communications Biology 2024, 7, 1024.
  • Wu LY, Real R, Martinez-Carrasco A, Chia R, Lawton MA, Shoai M, Bresner C, Blauwendraat C, Singleton AB, Ryten M, Scholz SW, Traynor BJ, Williams NM, Hu MTM, Ben-Shlomo Y, Grosset DG, Hardy J, Morris HR, Abramzon Y, Ahmed S, Alba C, Albert MS, Bacikova D, Barrett MJ, Beach TG, Bennett DA, Besser LM, Bigio EH, Boeve BF, Bohannan RC, Caraway CA, Palma J-A, Dalgard CL, Dickson D, Ding J, Faber K, Ferman T, Ferrucci L, Flanagan ME, Foroud TM, Ghetti B, Gibbs JR, Goate A, Goldstein D, Graff-Radford NR, Hu H-C, Hupalo D, Kaiser SM, Kaufmann H, Kim RC, Klein G, Kukull W, Kuzma A, Leverenz J, Lopez G, Mao Q, Martinez-McGrath E, Masliah E, Monuki E, Newell KL, Norcliffe-Kaufmann L, Perkins M, Pletnikova O, Renton AE, Resnick SM, Ross OA, Sabir MS, Scherzer CR, Serrano G, Shakkotai V, Sidransky E, Tanaka T, Tayebi N, Troncoso JC, Viollet C, Walton RL, Woltjer R, Wszolek ZK, Black SE, Gan-Or Z, Keith J, Masellis M, Rogaeva E, Aarsland D, Al-Sarraj S, Attems J, Ferrari R, Gentleman S, Hardy JA, Hodges AK, Love S, McKeith I, Morris CM, Palmer L, Pickering-Brown S, Reynolds RH, Thomas AJ, Tilley BS, Troakes C, Brett F, Brice A, Duyckaerts C, Lesage S, Brunetti M, Calvo A, Canosa A, Chio A, Floris G, Logroscino G, Zecca C, Clarimon J, Diez-Fairen M, Fortea J, Gonzalez-Aramburu I, Infante J, Lage C, Lleo A, Pastor P, Porcel-Molina L, Rodriguez-Rodriguez E, Sanchez-Juan P, Kruger R, May P, Xiromerisiou G. Investigation of the genetic aetiology of Lewy body diseases with and without dementia. Brain Communications 2024, 6(4).
  • Manzoni C, Kia DA, Ferrari R, Leonenko G, Costa B, Saba V, Jabbari E, Tan MM, Albani D, Alvarez V, Alvarez I, Andreassen OA, Angiolillo A, Arighi A, Baker M, Benussi L, Bessi V, Binetti G, Blackburn DJ, Boada M, Boeve BF, Borrego-Ecija S, Borroni B, Brathen G, Brooks WS, Bruni AC, Caroppo P, Bandres-Ciga S, Clarimon J, Colao R, Cruchaga C, Danek A, de Boer SC, de Rojas I, di Costanzo A, Dickson DW, Diehl-Schmid J, Dobson-Stone C, Dols-Icardo O, Donizetti A, Dopper E, Durante E, Ferrari C, Forloni G, Frangipane F, Fratiglioni L, Kramberger MG, Galimberti D, Gallucci M, Garcia-Gonzalez P, Ghidoni R, Giaccone G, Graff C, Graff-Radford NR, Grafman J, Halliday GM, Hernandez DG, Hjermind LE, Hodges JR, Holloway G, Huey ED, Illan-Gala I, Josephs KA, Knopman DS, Kristiansen M, Kwok JB, Leber I, Leonard HL, Libri I, Lleo A, Mackenzie IR, Madhan GK, Maletta R, Marquie M, Maver A, Menendez-Gonzalez M, Milan G, Miller BL, Morris CM, Morris HR, Nacmias B, Newton J, Nielsen JE, Nilsson C, Novelli V, Padovani A, Pal S, Pasquier F, Pastor P, Perneczky R, Peterlin B, Petersen RC, Piguet O, Pijnenburg YA, Puca AA, Rademakers R, Rainero I, Reus LM, Richardson AM, Riemenschneider M, Rogaeva E, Rogelj B, Rollinson S, Rosen H, Rossi G, Rowe JB, Rubino E, Ruiz A, Salvi E, Sanchez-Valle R, Sando SB, Santillo AF, Saxon JA, Schlachetzki JC, Scholz SW, Seelaar H, Seeley WW, Serpente M, Sorbi S, Sordon S, St George-Hyslop P, Thompson JC, Van Broeckhoven C, Van Deerlin VM, Van der Lee SJ, Van Swieten J, Tagliavini F, van der Zee J, Veronesi A, Vitale E, Waldo ML, Yokoyama JS, Nalls MA, Momeni P, Singleton AB, Hardy J, Escott-Price V. Genome-wide analyses reveal a potential role for the MAPT, MOBP, and APOE loci in sporadic frontotemporal dementia. American Journal of Human Genetics 2024, 111(7), 1316-1329.
  • Gee LMV, Barron-Millar B, Leslie J, Richardson C, Zaki MYW, Luli S, Burgoyne RA, Cameron RIT, Smith GR, Brain JG, Innes B, Jopson L, Dyson JK, McKay KRC, Pechlivanis A, Holmes E, Berlinguer-Palmini R, Victorelli S, Mells GF, Sandford RN, Palmer J, Kirby JA, Kiourtis C, Mokochinski J, Hall Z, Bird TG, Borthwick LA, Morris CM, Hanson PS, Jurk D, Stoll EA, LeBeau FEN, Jones DEJ, Oakley F. Anti–Cholestatic Therapy with Obeticholic Acid Improves Short-Term Memory in Bile Duct–Ligated Mice. American Journal of Pathology 2023, 193(1), 11-26.
  • Smajic S, Prada-Medina CA, Landoulsi Z, Ghelfi J, Delcambre S, Dietrich C, Jarazo J, Henck J, Balachandran S, Pachchek S, Morris CM, Antony P, Timmermann B, Sauer S, Pereira SL, Schwamborn JC, May P, Grunewald A, Spielmann M. Single-cell sequencing of human midbrain reveals glial activation and a Parkinson-specific neuronal state. Brain 2022, 145(3), 964-978.
  • Kurzawa-Akanbi M, Whitfield P, Burte F, Bertelli PM, Pathak V, Doherty M, Hilgen B, Gliaudelyte L, Platt M, Queen R, Coxhead J, Porter A, Oberg M, Fabrikova D, Davey T, Beh CS, Georgiou M, Collin J, Boczonadi V, Hartlova A, Taggart M, Al-Aama J, Korolchuk VI, Morris CM, Guduric-Fuchs J, Steel DH, Medina RJ, Armstrong L, Lako M. Retinal pigment epithelium extracellular vesicles are potent inducers of age-related macular degeneration disease phenotype in the outer retina. Journal of Extracellular Vesicles 2022, 11(12), 12295.
  • Ng YS, Lax NZ, Blain AP, Erskine D, Baker MR, Polvikoski T, Thomas RH, Morris CM, Lai M, Whittaker RG, Gebbels A, Winder A, Hall J, Feeney C, Farrugia ME, Hirst C, Roberts M, Lawthom C, Chrysostomou A, Murphy K, Baird T, Maddison P, Duncan C, Poulton J, Nesbitt V, Hanna MG, Pitceathly RDS, Taylor RW, Blakely EL, Schaefer AM, Turnbull DM, McFarland R, Gorman GS. Forecasting stroke-like episodes and outcomes in mitochondrial disease. Brain 2022, 145(2), 542-554.
  • Donaghy PC, Cockell SJ, Martin-Ruiz C, Coxhead J, Kane J, Erskine D, Koss D, Taylor JP, Morris CM, O'Brien JT, Thomas AJ. Blood mRNA expression in Alzheimer’s disease and dementia with Lewy bodies. American Journal of Geriatric Psychiatry 2022, 30(9), 964-975.
  • Poggiolini I, Erskine D, Vaikath NN, Ponraj J, Mansour S, Morris CM, El-Agnaf OMA. RT-QuIC using C-terminally truncated a-synuclein forms detects differences in seeding propensity of different brain regions from synucleinopathies. Biomolecules 2021, 11(6), 820.
  • Kurzawa-Akanbi M, Keogh M, Tsefou E, Ramsay L, Johnson M, Keers S, Ochieng LW, McNair A, Singh P, Khan A, Pyle A, Hudson G, Ince PG, Attems J, Burn J, Chinnery PF, Morris CM. Neuropathological and Biochemical Investigation of Hereditary Ferritinopathycases with Ferritin Light Chain Mutation: Prominent Protein Aggregation in the Absence of Major Mitochondrial or Oxidative Stress. Neuropathology and Applied Neurobiology 2021, 47(1), 26-42.
  • Tweedy C, Kindred N, Curry J, Williams C, Taylor J-P, Atkinson P, Randall F, Erskine D, Morris CM, Reeve AK, Clowry GJ, LeBeau FEN. Hippocampal network hyperexcitability in young transgenic mice expressing human mutant alpha-synuclein. Neurobiology of Disease 2021, 149, 105226.
  • Kurzawa-Akanbi M, Tammireddy S, Fabrik I, Gliaudelyte L, Doherty MK, Heap R, Matecko-Burmann I, Burmann BM, Trost M, Lucocq JM, Gherman AV, Fairfoul G, Singh P, Burte F, Green A, McKeith IG, Härtlova A, Whitfield PD, Morris CM. Altered ceramide metabolism is a feature in the extracellular vesicle-mediated spread of alpha-synuclein in Lewy body disorders. Acta Neuropathologica 2021, 142, 961-984.
  • Thomas AJ, Hamilton CA, Donaghy PC, Martin-Ruiz C, Morris CM, Barnett N, Olsen K, Taylor JP, O'Brien JT. Prospective Longitudinal Evaluation of Cytokines in mild cognitive impairment due to AD and Lewy Body Disease. International Journal of Geriatric Psychiatry 2020, 35(10), 1250-1259.
  • Brooks J, Everett J, Lermyte F, Tjhin VT, Banerjee S, O'Connor PB, Morris CM, Sadler PJ, Telling ND, Collingwood JF. Label-Free Nanoimaging of Neuromelanin in the Brain by Soft X-ray Spectromicroscopy. Angewandte Chemie - International Edition 2020, 59(29), 11984-11991.
  • Brooks J, Everett J, Lermyte F, Tjhin VT, Banerjee S, O'Connor PB, Morris CM, Sadler PJ, Telling ND, Collingwood JF. Label-Free Nanoimaging of Neuromelanin in the Brain by Soft X-ray Spectromicroscopy. Angewandte Chemie 2020, 132(29), 12082-12089.
  • Fayyad M, Erskine D, Majbour NK, Vaikath NV, Ghanem SS, Sudhakaran IP, Abdesselem H, Lamprokostopoulou A, Vekrellis K, Morris CM, Attems J, El-Agnaf OMA. Investigating the Presence of Doubly‐phosphorylated α‐Synuclein at Tyrosine 125 and Serine 129 In Idiopathic Lewy Body Diseases. Brain Pathology 2020, 30(4), 831-843.
  • Blauwendraat C, Reed X, Krohn L, Heilbron K, Bandres-Ciga S, Tan M, Gibbs JR, Hernandez DG, Kumaran R, Langston R, Bonet-Ponce L, Alcalay RN, Hassin-Baer S, Greenbaum L, Iwaki H, Leonard HL, Grenn FP, Ruskey JA, Sabir M, Ahmed S, Makarious MB, Pihlstrom L, Toft M, van Hilten JJ, Marinus J, Schulte C, Brockmann K, Sharma M, Siitonen A, Majamaa K, Eerola-Rautio J, Tienari PJ, Pantelyat A, Hillis AE, Dawson TM, Rosenthal LS, Albert MS, Resnick SM, Ferrucci L, Morris CM, Pletnikova O, Troncoso J, Grosset D, Lesage S, Corvol J-C, Brice A, Noyce AJ, Masliah E, Wood N, Hardy J, Shulman LM, Jankovic J, Shulman JM, Heutink P, Gasser T, Cannon P, Scholz SW, Morris H, Cookson MR, Nalls MA, Gan-Or Z, Singleton AB, on behalf of the International Parkinson's Disease Genomics Consortium (IPDGC). Genetic modifiers of risk and age at onset in GBA associated Parkinson's disease and Lewy body dementia. Brain 2020, 143(1), 234-248.
  • Costa B, Manzoni C, Bernal-Quiros M, Kia DA, Aguilar M, Alvarez I, Alvarez V, Andreassen OA, Anfossi M, Bagnoli S, Benussi L, Bernardi L, Binetti G, Blackburn DJ, Boada M, Borroni B, Bowns L, Brathen G, Bruni AC, Chiang H-H, Clarimon J, Colville S, Conidi ME, Cope TE, Cruchaga C, Cupidi C, Di Battista ME, Diehl-Schmid J, Diez-Fairen M, Dols-Icardo O, Durante E, Flisar D, Frangipane F, Galimberti D, Gallo M, Gallucci M, Ghidoni R, Graff C, Grafman JH, Grossman M, Hardy J, Hernandez I, Holloway GJT, Huey ED, Illan-Gala I, Karydas A, Khoshnood B, Kramberger MG, Kristiansen M, Lewis PA, Lleo A, Madhan GK, Maletta R, Maver A, Menendez-Gonzalez M, Milan G, Miller BL, Mol MO, Momeni P, Moreno-Grau S, Morris CM, Nacmias B, Nilsson C, Novelli V, Oijerstedt L, Padovani A, Pal S, Panchbhaya Y, Pastor P, Peterlin B, Piaceri I, Pickering-Brown S, Pijnenburg YAL, Puca AA, Rainero I, Rendina A, Richardson AMT, Rogaeva E, Rogelj B, Rollinson S, Rossi G, Rossmeier C, Rowe JB, Rubino E, Ruiz A, Sanchez-Valle R, Sando SB, Santillo AF, Saxon J, Scarpini E, Serpente M, Smirne N, Sorbi S, Suh E, Tagliavini F, Thompson JC, Trojanowski JQ, van Deerlin VM, van der Zee J, van Broeckhoven C, van Rooij JGJ, van Swieten JC, Veronesi A, Vitale E, Waldo ML, Woodward C, Yokoyama JS, Escott-Price V, Polke JM, Ferrari R. C9orf72, age at onset, and ancestry help discriminate behavioral from language variants in FTLD cohorts. Neurology 2020, 95(24), e3288-e3302.
  • Keane PC, Hanson PS, Patterson L, Blain PG, Hepplewhite P, Khundakar AA, Judge SJ, Kahle PJ, LeBeau FEN, Morris CM. Trichloroethylene and its metabolite TaClo lead to degeneration of substantia nigra dopaminergic neurones: Effects in wild type and human A30P mutant α-synuclein mice . Neuroscience Letters 2019, 711, 134437.
  • King E, O'Brien JT, Donaghy P, Morris C, Barnett N, Olsen K, Martin-Ruiz C, Taylor JP, Thomas AJ. Peripheral inflammation in mild cognitive impairment with possible and probable Lewy body disease and Alzheimer’s disease. International Psychogeriatrics 2019, 31(4), 551-560.
  • Erskine D, Taylor JP, Thomas A, Collerton D, McKeith I, Khundakar A, Attems J, Morris C. Pathological Changes to the Subcortical Visual System and its Relationship to Visual Hallucinations in Dementia with Lewy Bodies. Neuroscience Bulletin 2019, 35, 295-300.
  • Patterson L, Firbank MJ, Colloby SJ, Attems J, Thomas AJ, Morris CM. Neuropathological Changes in Dementia With Lewy Bodies and the Cingulate Island Sign. Journal of Neuropathology and Experimental Neurology 2019, 78(8), 717–724.
  • King E, O'Brien J, Donaghy P, Williams-Gray CH, Lawson RA, Morris CM, Barnett N, Olsen K, Martin-Ruiz C, Burn DJ, Yarnall AJ, Taylor JP, Duncan GW, Khoo TK, Thomas A. Inflammation in Mild Cognitive Impairment due to Parkinson’s disease, Lewy Body disease and Alzheimer’s disease. International Journal of Geriatric Psychiatry 2019, 34(8), 1244-1250.
  • Swarup V, Hinz FI, Rexach JE, Noguchi K, Toyoshiba H, Oda A, Hirai K, Sarkar A, Seyfried NT, Cheng C, Haggarty SJ, International Frontotemporal Dementia Genetics Consortium, (Includes, Morris CM, Attems J, Griffiths TD, McKeith IG, Thomas AJ, Jaros E), Grossman M, Van Deerlin VM, Trojanowski JQ, Lah JJ, Levey AI, Kondou S, Geschwind DH. Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia. Nature Medicine 2019, 25, 152-164.
  • Vaikath NN, Erskine D, Morris CM, Majbour N, Vekrellis K, Li JY, El-Agnaf OMA. Heterogeneity in α-synuclein sub-types and their expression in cortical brain tissue lysates from Lewy body diseases and Alzheimer's disease. Neuropathology and Applied Neurobiology 2019, 45(6), 597-608.
  • Bonham LW, Steele NZR, Karch CM, Broce I, Geier EG, Wen NL, Momeni P, Hardy J, Miller ZA, Gorno-Tempini ML, Hess CP, Lewis P, Miller BL, Seeley WW, Manzoni C, Desikan RS, Baranzini SE, Ferrari R, Yokoyama JS, Hernandez DG, Nalls MA, Rohrer JD, Ramasamy A, Kwok JBJ, Dobson-Stone C, Schofield PR, Halliday GM, Hodges JR, Piguet O, Bartley L, Thompson E, Haan E, Hernandez I, Ruiz A, Boada M, Borroni B, Padovani A, Cruchaga C, Cairns NJ, Benussi L, Binetti G, Ghidoni R, Forloni G, Albani D, Galimberti D, Fenoglio C, Serpente M, Scarpini E, Clarimon J, Lleo A, Blesa R, Landqvist Waldo M, Nilsson K, Nilsson C, Mackenzie IRA, Hsiung G-YR, Mann DMA, Grafman J, Morris CM, Attems J, Griffiths TD, McKeith IG, Thomas AJ, Pietrini P, Huey ED, Wassermann EM, Baborie A, Jaros E, Tierney MC, Pastor P, Razquin C, Ortega-Cubero S, Alonso E, Perneczky R, Diehl-Schmid J, Alexopoulos P, Kurz A, Rainero I, Rubino E, Pinessi L, Rogaeva E, St George-Hyslop P, Rossi G, Tagliavini F, Giaccone G, Rowe JB, Schlachetzki JCM, Uphill J, Collinge J, Mead S, Danek A, Van Deerlin VM, Grossman M, Trojanowski JQ, van der Zee J, Cruts M, VanBroeckhoven C, Cappa SF, Leber I, Hannequin D, Golfier V, Vercelletto M, Brice A, Nacmias B, Sorbi S, Bagnoli S, Piaceri I, Nielsen JE, Hjermind LE, Riemenschneider M, Mayhaus M, Ibach B, Gasparoni G, Pichler S, Gu W, Rossor MN, Fox NC, Warren JD, Spillantini MG, Morris HR, Rizzu P, Heutink P, Snowden JS, Rollinson S, Richardson A, Gerhard A, Bruni AC, Maletta R, Frangipane F, Cupidi C, Bernardi L, Anfossi M, Gallo M, Conidi ME, Smirne N, Rademakers R, Baker M, Dickson DW, Graff-Radford NR, Petersen RC, Knopman D, Josephs KA, Boeve BF, Parisi JE, Karydas AM, Rosen H, van Swieten JC, Dopper EGP, Seelaar H, Pijnenburg YAL, Scheltens P, Logroscino G, Capozzo R, Novelli V, Puca AA, Franceschi M, Postiglione A, Milan G, Sorrentino P, Kristiansen M, Chiang H-H, Graff C, Pasquier F, Rollin A, Deramecourt V, Lebouvier T, Kapogiannis D, Ferrucci L, Pickering-Brown S, Singleton AB. Genetic variation across RNA metabolism and cell death gene networks is implicated in the semantic variant of primary progressive aphasia. Scientific Reports 2019, 9, 10854.
  • Wei W, Keogh MJ, Aryaman J, Golder Z, Kullar PJ, Wilson I, Talbot K, Turner MR, McKenzie C-A, Troakes C, Attems J, Smith C, Sarraj SA, Morris CM, Ansorge O, Jones NS, Ironside JW, Chinnery PF. Frequency and signature of somatic variants in 1461 human brain exomes. Genetics in Medicine 2019, 21, 904-912.
  • Outeiro TF, Koss DJ, Erskine D, Walker L, Kurzawa-Akanbi M, Burn DJ, Donaghy P, Morris CM, Taylor JP, Thomas AJ, Attems J, McKeith IG. Dementia with Lewy bodies: an update and outlook. Molecular Neurodegeneration 2019, 14, 5.
  • Patterson L, Rushton SP, Attems J, Thomas AJ, Morris CM. Degeneration of dopaminergic circuitry influences depressive symptoms in Lewy body disorders. Brain Pathology 2019, 29(4), 544-557.
  • Sabir MS, Blauwendraat C, Ahmed S, Serrano GE, Beach TG, Perkins M, Rice AC, Masliah E, Morris CM, Pihlstrom L, Pantelyat A, Resnick SM, Cookson MR, Hernandez DG, Albert M, Dawson TM, Rosenthal LS, Houlden H, Pletnikova O, Troncoso J, Scholz SW. Assessment of APOE in atypical parkinsonism syndromes. Neurobiology of Disease 2019, 127, 142-146.
  • van der Lee SJ, Conway OJ, Jansen I, Carrasquillo MM, Kleineidam L, van den Akker E, Hernandez I, van Eijk KR, Stringa N, Chen JA, Zettergren A, Andlauer TFM, Diez-Fairen M, Simon-Sanchez J, Lleo A, Zetterberg H, Nygaard M, Blauwendraat C, Savage JE, Mengel-From J, Moreno-Grau S, Wagner M, Fortea J, Keogh MJ, Blennow K, Skoog I, Friese MA, Pletnikova O, Zulaica M, Lage C, de Rojas I, Riedel-Heller S, Illan-Gala I, Wei W, Jeune B, Orellana A, Then Bergh F, Wang X, Hulsman M, Beker N, Tesi N, Morris CM, Indakoetxea B, Collij LE, Scherer M, Morenas-Rodriguez E, Ironside JW, van Berckel BNM, Alcolea D, Wiendl H, Strickland SL, Pastor P, Rodriguez Rodriguez E, Boeve BF, Petersen RC, Ferman TJ, van Gerpen JA, Reinders MJT, Uitti RJ, Tarraga L, Maier W, Dols-Icardo O, Kawalia A, Dalmasso MC, Boada M, Zettl UK, van Schoor NM, Beekman M, Allen M, Masliah E, de Munain AL, Pantelyat A, Wszolek ZK, Ross OA, Dickson DW, Graff-Radford NR, Knopman D, Rademakers R, Lemstra AW, Pijnenburg YAL, Scheltens P, Gasser T, Chinnery PF, Hemmer B, Huisman MA, Troncoso J, Moreno F, Nohr EA, Sorensen TIA, Heutink P, Sanchez-Juan P, Posthuma D, Coppola G, Karydas AM, Varpetian A, Foroud TM, Levey AI, Kukull WA, Mendez MF, Ringman J, Chui H, Cotman C, DeCarli C, Miller BL, Geschwind DH, Clarimon J, Christensen K, Ertekin-Taner N, Scholz SW, Ramirez A, Ruiz A, Slagboom E, van der Flier WM, Holstege H. A nonsynonymous mutation in PLCG₂ reduces the risk of Alzheimer’s disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity. Acta Neuropathologica 2019, 138(2), 237-250.
  • Ahmed S, Fairen MD, Sabir MS, Pastor P, Ding J, Ispierto L, Butala A, Morris CM, Schulte C, Gasser T, Jabbari E, Pletnikova O, Morris HR, Troncoso J, Gelpi E, Pantelyat A, Scholz SW. MAPT p.V363I mutation: A rare cause of corticobasal degeneration. Neurology Genetics 2019, 5(4), e347.
  • Cali CP, Patino M, Tai YK, Ho WY, McLean CA, Morris CM, Seeley WW, Miller BL, Gaig C, Vonsattel JPG, White CL, Roeber S, Kretzschmar H, Troncoso JC, Troakes C, Gearing M, Ghetti B, Van Deerlin VM, Lee VM, Trojanowski JQ, Mok KY, Ling H, Dickson DW, Schellenberg GD, Ling SC, Lee EB. C9orf72 intermediate repeats are associated with corticobasal degeneration, increased C9orf72 expression and disruption of autophagy. Acta Neuropathologica 2019, 138, 795-811.
  • Petyuk VA, Chang R, Ramirez-Restrepo M, Beckmann ND, Henrion MYR, Piehowski PD, Zhu K, Wang S, Clarke J, Huentelman MJ, Xie F, Andreev V, Engel A, Guettoche T, Navarro L, De Jager P, Schneider JA, Morris CM, McKeith IG, Perry RH, Lovestone S, Woltjer RL, Beach TG, Sue LI, Serrano GE, Lieberman AP, Albin RL, Ferrer I, Mash DC, Hulette CM, Ervin JF, Reiman EM, Hardy JA, Bennett DA, Schadt E, Smith RD, Myers AJ. The human brainome: network analysis identifies HSPA2 as a novel Alzheimer’s disease target. Brain 2018, 141(9), 2721-2739.
  • Nicolas G, Acuna-Hidalgo R, Keogh MJ, Quenez O, Steehouwer M, Lelieveld S, Rousseau S, Richard A-C, Oud MS, Marguet F, Laquerriere A, Morris CM, Attems J, Smith C, Ansorge O, Al Sarraj S, Frebourg T, Campion D, Hannequin D, Wallon D, Gilissen C, Chinnery PF, Veltman JA, Hoischen A. Somatic variants in autosomal dominant genes are a rare cause of sporadic Alzheimer's disease. Alzheimer's and Dementia 2018, 14(12), 1632-1639.
  • Erskine D, Patterson L, Alexandris A, Hanson PS, McKeith IG, Attems J, Morris CM. Regional levels of physiological α-synuclein are directly associated with Lewy body pathology. Acta Neuropathologica 2018, 135(1), 153-154.
  • King E, O'Brien JT, Donaghy P, Morris C, Barnett N, Olsen K, Martin-Ruiz C, Taylor J-P, Thomas AJ. Peripheral inflammation in prodromal Alzheimer’s and Lewy body dementias. Journal of Neurology, Neurosurgery and Psychiatry 2018, 89(4), 339-345.
  • Keogh MJ, Wei W, Aryaman J, Wilson I, Talbot K, Turner MR, McKenzie C-A, Troakes C, Attems J, Smith C, AlSarraj S, Morris CM, Ansorge O, Pickering-Brown S, Jones N, Ironside JW, Chinnery PF. Oligogenic genetic variation of neurodegenerative disease genes in 980 postmortem human brains. Journal of Neurology, Neurosurgery and Psychiatry 2018, 89(8), 813-816.
  • Erskine D, Ding J, Thomas AJ, Kaganovich A, Khundakar AA, Hanson PS, Taylor JP, McKeith IG, Attems J, Cookson MR, Morris CM. Molecular changes in the absence of severe pathology in the pulvinar in dementia with Lewy bodies. Movement Disorders 2018, 33(6), 982-991.
  • Reeve AK, Grady JP, Cosgrave EM, Bennison E, Chen C, Hepplewhite PD, Morris CM. Mitochondrial dysfunction within the synapses of substantia nigra neurons in Parkinson’s disease. npj Parkinson's Disease 2018, 4, 9.
  • Nisar R, Hanson PS, Keane PC, He L, Taylor R, Blain PG, Morris CM. Manganese-Containing Thiocarbamates Cause Free Radical Production and Caspase-Independent Cell Death following Mitochondrial Dysfunction in Neural Cells. Reactive Oxygen Species 2018, 6(18), 428-444.
  • Keogh MJ, Wei W, Aryaman J, Walker L, van den Ameele J, Coxhead J, Wilson I, Bashton M, Beck J, West J, Chen R, Haudenschild C, Bartha G, Luo S, Morris CM, Jones NS, Attems J, Chinnery PF. High prevalence of focal and multi-focal somatic genetic variants in the human brain. Nature Communications 2018, 9(1), 4257.
  • Savy CS, Fitchett AE, Blain PG, Morris CM, Judge SJ. Gene expression analysis reveals chronic low level exposure to the pesticide diazinon affects Psychological Disorders gene sets in the adult rat. Toxicology 2018, 393, 90-101.
  • Lock EA, Keane P, Rowe PH, Foster JR, Antoine D, Morris CM. Trichloroethylene-induced formic aciduria in the male C₅₇ Bl/6 mouse. Toxicology 2017, 378, 76-85.
  • Erskine D, Thomas AJ, Attems J, Taylor JP, McKeith IG, Morris CM, Khundakar AA. Specific patterns of neuronal loss in the pulvinar nucleus in dementia with Lewy bodies. Movement Disorders 2017, 32(3), 414-422.
  • Singh P, Hanson PS, Morris CM. Sirtuin-2 Protects Neural Cells from Oxidative Stress and Is Elevated in Neurodegeneration. Parkinson's Disease 2017, 2017, 1-17.
  • Singh P, Hanson PS, Morris CM. SIRT1 ameliorates oxidative stress induced neural cell death and is down-regulated in Parkinson’s disease. BMC Neuroscience 2017, 18(1), 46.
  • Erskine D, Thomas AJ, Taylor JP, Savage MA, Attems J, McKeith IG, Morris CM, Khundakar AA. Neuronal Loss and Α-Synuclein Pathology in the Superior Colliculus and Its Relationship to Visual Hallucinations in Dementia with Lewy Bodies. The American Journal of Geriatric Psychiatry 2017, 25(6), 595-604.
  • Wei W, Keogh MJ, Wilson I, Coxhead J, Ryan S, Rollinson S, Griffin H, Kurzawa-Akanbi M, Santibanez-Koref M, Talbot K, Turner MR, McKenzie CA, Troakes C, Attems J, Smith C, Al Sarraj S, Morris CM, Ansorge O, Pickering-Brown S, Ironside JW, Chinnery PF. Mitochondrial DNA point mutations and relative copy number in 1363 disease and control human brains. Acta Neuropathologica Communications 2017, 5, 17.
  • Bury AG, Pyle A, Elson JL, Greaves L, Morris CM, Hudson G, Pienaar IS. Mitochondrial DNA changes in pedunculopontine cholinergic neurons in Parkinson disease. Annals of Neurology 2017, 82(6), 1016-1021.
  • Keogh MJ, Wei W, Wilson I, Coxhead J, Ryan S, Rollinson S, Griffin H, Kurzawa-Akanbi M, Santibariez-Koref M, Talbot K, Turner MR, McKenzie CA, Troakes C, Attems J, Smith C, Al Sarraj S, Morris CM, Ansorge O, Pickering-Brown S, Ironside JW, Chinnery PF. Genetic compendium of 1511 human brains available through the UK Medical Research Council Brain Banks Network Resource. Genome Reseach 2017, 27(1), 165-173.
  • Ishaq A, Hanson PS, Morris CM, Saretzki G. Telomerase Activity is Downregulated Early During Human Brain Development. Genes 2016, 7(6), 27.
  • Grunewald A, Rygiel KA, Hepplewhite PD, Morris CM, Picard M, Turnbull DM. Mitochondrial DNA Depletion in Respiratory Chain-Deficient Parkinson Disease Neurons. Annals of Neurology 2016, 79(3), 366-378.
  • Judge SJ, Savy CY, Campbell M, Dodds R, Gomes LK, Laws G, Watson A, Blain PG, Morris CM, Gartside SE. Mechanism for the acute effects of organophosphate pesticides on the adult 5-HT system. Chemico-Biological Interactions 2016, 245, 82-89.
  • Keogh MJ, Kurzawa-Akanbi M, Griffin H, Douroudis K, Ayers KL, Hussein RI, Hudson G, Pyle A, Cordell HJ, Attems J, McKeith IG, O'Brien JT, Burn DJ, Morris CM, Thomas AJ, Chinnery PF. Exome sequencing in dementia with Lewy bodies. Translational Psychiatry 2016, 6, e728.
  • Phillips J, Laude A, Lightowlers R, Morris CM, Turnbull DM, Lax NZ. Development of passive CLARITY and immunofluorescent labelling of multiple proteins in human cerebellum: understanding mechanisms of neurodegeneration in mitochondrial disease. Scientific Reports 2016, 6, 26013.
  • Vergani F, Martino J, Morris C, Attems J, Ashkan K, Dell'Acqua F. Anatomic Connections of the Subgenual Cingulate Region. Neurosurgery 2016, 79(3), 465-472.
  • Khundakar AA, Hanson PS, Erskine D, Lax NZ, Roscamp J, Karyka E, Tsefou E, Singh P, Cockell SJ, Gribben A, Ramsay L, Blain PJ, Mosimann UP, Lett DJ, Elstner M, Turnbull DM, Xiang CC, Brownstein MJ, O'Brien JT, Taylor JP, Attems J, Thomas AJ, McKeith IG, Morris CM. Analysis of primary visual cortex in dementia with Lewy bodies indicates GABAergic involvement associated with recurrent complex visual hallucinations. Acta Neuropathologica Communications 2016, 4, 66.
  • Modebadze T, Morgan NH, Peres IAA, Hadid RD, Amada N, Hill C, Williams C, Stanford IM, Morris CM, Jones RSG, Whalley BJ, Woodhall GL. A Low Mortality, High Morbidity Reduced Intensity Status Epilepticus (RISE) Model of Epilepsy and Epileptogenesis in the Rat. PLoS ONE 2016, 11(2), e0147265.
  • Chiasserini D, Paciotti S, Eusebi P, Persichetti E, Tasegian A, Kurzawa-Akanbi M, Chinnery PF, Morris CM, Calabresi P, Parnetti L, Beccari T. Selective loss of glucocerebrosidase activity in sporadic Parkinson's disease and dementia with Lewy bodies. Molecular Neurodegeneration 2015, 10(1), 1-13.
  • Hill SL, Thomas SHL, Flecknell PA, Thomas AA, Morris CM, Henderson D, Dunn M, Blain PG. Rapid and equivalent systemic bioavailability of the antidotes HI-6 and dicobalt edetate via the intraosseous and intravenous routes. Emergency Medicine Journal 2015, 32(8), 626-631.
  • Madgwick A, Fort P, Hanson PS, Thibault P, Gaudreau MC, Lutfalla G, Möröy T, Abou-Elela S, Chaudhry B, Elliott DJ, Morris CM, Venables JP. Neural Differentiation Modulates the Vertebrate Brain Specific Splicing Program. PLoS One 2015, 10(5), e0125998.
  • Savy CY, Fitchett AE, McQuade R, Gartside SE, Morris CM, Blain PG, Judge SJ. Low-level repeated exposure to diazinon and chlorpyrifos decrease anxiety-like behaviour in adult male rats as assessed by marble burying behaviour. Neurotoxicology 2015, 50, 149-156.
  • Nisar R, Hanson PS, He L, Taylor RW, Blain PG, Morris CM. Diquat causes caspase-independent cell death in SH-SY₅Y cells by production of ROS independently of mitochondria. Archives of Toxicology 2015, 89(10), 1811-1825.
  • Erskine D, Taylor JP, Firbank MJ, Patterson L, Onofrj M, O'Brien JT, McKeith IG, Attems J, Thomas AJ, Morris CM, Khundakar AA. Changes to the lateral geniculate nucleus in Alzheimer's disease but not dementia with Lewy bodies. Neuropathology and Applied Neurobiology 2015, 42(4), 366–376.
  • Vergani F, Lacerda L, Martino J, Attems J, Morris C, Mitchell P, de Schotten MT, Dell'Acqua F. White matter connections of the supplementary motor area in humans. Journal of Neurology, Neurosurgery & Psychiatry 2014, 85(12), 1377-1385.
  • Mandler M, Walker L, Santic R, Hanson P, Upadhaya AR, Colloby SJ, Morris CM, Thal DR, Thomas AJ, Schneeberger A, Attems J. Pyroglutamylated amyloid-β is associated with hyperphosphorylated tau and severity of Alzheimer’s disease. Acta Neuropathologica 2014, 128(1), 67-79.
  • Vergani F, Mahmood S, Morris CM, Mitchell P, Forkel SJ. Intralobar fibres of the occipital lobe: A post mortem dissection study. Cortex 2014, 56, 145-156.
  • Ferrari R, Hernandez DG, Nalls MA, Rohrer JD, Ramasamy A, Kwok JBJ, Dobson-Stone C, Brooks WS, Schofield PR, Halliday GM, Hodges JR, Piguet O, Bartley L, Thompson E, Haan E, Hernandez I, Ruiz A, Boada M, Borroni B, Padovani A, Cruchaga C, Cairns NJ, Benussi L, Binetti G, Ghidoni R, Forloni G, Galimberti D, Fenoglio C, Serpente M, Scarpini E, Clarimon J, Lleo A, Blesa R, Waldo ML, Nilsson K, Nilsson C, Mackenzie IRA, Hsiung GYR, Mann DMA, Grafman J, Morris CM, Attems J, Griffiths TD, McKeith IG, Thomas AJ, Pietrini P, Huey ED, Wassermann EM, Baborie A, Jaros E, Tierney MC, Pastor P, Razquin C, Ortega-Cubero S, Alonso E, Perneczky R, Diehl-Schmid J, Alexopoulos P, Kurz A, Rainero I, Rubino E, Pinessi L, Rogaeva E, St George-Hyslop P, Rossi G, Tagliavini F, Giaccone G, Rowe JB, Schlachetzki JCM, Uphill J, Collinge J, Mead S, Danek A, Van Deerlin VM, Grossman M, Trojanowski JQ, van der Zee J, Deschamps W, Van Langenhove T, Cruts M, Van Broeckhoven C, Cappa SF, Le Ber I, Hannequin D, Golfier V, Vercelletto M, Brice A, Nacmias B, Sorbi S, Bagnoli S, Piaceri I, Nielsen JE, Hjermind LE, Riemenschneider M, Mayhaus M, Ibach B, Gasparoni G, Pichler S, Gu W, Rossor MN, Fox NC, Warren JD, Spillantini MG, Morris HR, Rizzu P, Heutink P, Snowden JS, Rollinson S, Richardson A, Gerhard A, Bruni AC, Maletta R, Frangipane F, Cupidi C, Bernardi L, Anfossi M, Gallo M, Conidi ME, Smirne N, Rademakers R, Baker M, Dickson DW, Graff-Radford NR, Petersen RC, Knopman D, Josephs KA, Boeve BF, Parisi JE, Seeley WW, Miller BL, Karydas AM, Rosen H, van Swieten JC, Dopper EGP, Seelaar H, Al Pijnenburg Y, Scheltens P, Logroscino G, Capozzo R, Novelli V, Puca AA, Franceschi M, Postiglione A, Milan G, Sorrentino P, Kristiansen M, Chiang HH, Graff C, Pasquier F, Rollin A, Deramecourt V, Lebert F, Kapogiannis D, Ferrucci L, Pickering-Brown S, Singleton AB, Hardy J, Momeni P. Frontotemporal dementia and its subtypes: a genome-wide association study. Lancet Neurology 2014, 13(7), 686-699.
  • Majounie E, Cross W, Newsway V, Dillman A, Vandrovcova J, Morris CM, Nalls MA, Ferrucci L, Owen MJ, O'Donovan MC, Cookson MR, Singleton AB, de Silva R, Morris HR. Variation in tau isoform expression in different brain regions and disease states. Neurobiology of Aging 2013, 34(7), 1922.e7-1922.e12.
  • Baron AW, Rushton SP, Rens N, Morris CM, Blain PG, Judge SJ. Sex differences in effects of low level domoic acid exposure. NeuroToxicology 2013, 34, 1-8.
  • Pienaar I-S, Elson JL, Racca C, Nelson G, Turnbull DM, Morris CM. Mitochondrial Abnormality Associates with Type-Specific Neuronal Loss and Cell Morphology Changes in the Pedunculopontine Nucleus in Parkinson Disease. American Journal of Pathology 2013, 183(6), 1826-1840.
  • Nalls MA, Duran R, Lopez G, Kurzawa-Akanbi M, McKeith IG, Chinnery PF, Morris CM, Theuns J, Crosiers D, Cras P, Engelborghs S, DeDeyn PP, Van Broeckhoven C, Mann DM, Snowden J, Pickering-Brown S, Halliwell N, Davidson Y, Gibbons L, Harris J, Sheerin UM, Bras J, Hardy J, Clark L, Marder K, Honig LS, Berg D, Maetzler W, Brockmann K, Gasser T, Novellino F, Quattrone A, Annesi G, De Marco EV, Rogaeva E, Masellis M, Black SE, Bilbao JM, Foroud T, Ghetti B, Nichols WC, Pankratz N, Halliday G, Lesage S, Klebe S, Durr A, Duyckaerts C, Brice A, Giasson BI, Trojanowski JQ, Hurtig HI, Tayebi N, Landazabal C, Knight MA, Keller M, Singleton AB, Wolfsberg TG, Sidransky E. A Multicenter Study of Glucocerebrosidase Mutations in Dementia With Lewy Bodies. JAMA Neurology 2013, 70(6), 727-735.
  • Fitchett AE, Judge SJ, Morris CM. Using olive oil to orally dose laboratory rats. Animal Technology and Welfare 2012, 10(1), 39-41.
  • Lehmann DJ, Schuur M, Warden DR, Hammond N, Belbin O, Kolsch H, Lehmann MG, Wilcock GK, Brown K, Kehoe PG, Morris CM, Barker R, Coto E, Alvarez V, Deloukas P, Mateo I, Gwilliam R, Combarros O, Arias-Vasquez A, Aulchenko YS, Ikram MA, Breteler MM, van Duijn CM, Oulhaj A, Heun R, Cortina-Borja M, Morgan K, Robson K, Smith AD. Transferrin and HFE genes interact in Alzheimer's disease risk: the Epistasis Project. Neurobiology of Aging 2012, 33(1), 202.e1.
  • Reeve AK, Park TK, Jaros E, Campbell GR, Lax NZ, Hepplewhite PD, Krishnan KJ, Elson JL, Morris CM, McKeith IG, Turnbull DM. Relationship Between Mitochondria and α-Synuclein: A Study of Single Substantia Nigra Neurons. Archives of Neurology 2012, 69(3), 385-393.
  • Boulton SJ, Keane PC, Morris CM, McNeil CJ, Manning P. Real-time monitoring of superoxide generation and cytotoxicity in neuroblastoma mitochondria induced by 1-trichloromethyl-1,2,3,4-tetrahydro-beta-carboline. Redox Report 2012, 17(3), 108-114.
  • Vergani F, Morris CM, Mitchell P, Duffau H. Raymond de Vieussens and his contribution to the study of white matter anatomy: Historical vignette. Journal of Neurosurgery 2012, 117(6), 1070-1075.
  • Kurzawa-Akanbi M, Hanson PS, Blain PG, Lett DJ, McKeith IG, Chinnery PF, Morris CM. Glucocerebrosidase Mutations alter the endoplasmic reticulum and lysosomes in Lewy body disease. Journal of Neurochemistry 2012, 123(2), 298-309.
  • Huey ED, Ferrari R, Moreno JH, Jensen C, Morris CM, Potocnik F, Kalaria RN, Tierney M, Wassermann EM, Hardy J, Grafman J, Momeni P. FUS and TDP43 genetic variability in FTD and CBS. Neurobiology of Aging 2012, 33(5), 1016.e9–1016.e17.
  • Elstner M, Muller SK, Leidolt L, Laub C, Krieg L, Schlaudraff F, Liss B, Morris C, Turnbull DM, Masliah E, Prokisch H, Klopstock T, Bender A. Neuromelanin, neurotransmitter status and brainstem location determine the differential vulnerability of catecholaminergic neurons to mitochondrial DNA deletions. Molecular Brain 2011, 4, 43.
  • Khundakar A, Morris C, Oakley A, Thomas AJ. Morphometric analysis of neuronal and glial cell pathology in the caudate nucleus in late-life depression. American Journal Geriatric Psychiatry 2011, 19(2), 132-141.
  • Keane PC, Kurzawa M, Blain PG, Morris CM. Mitochondrial dysfunction in Parkinson's Disease. Parkinson's Disease 2011, 2011, 716871.
  • Elstner M, Morris CM, Heim K, Bender A, Mehta D, Jaros E, Klopstock T, Meitinger T, Turnbull DM, Prokisch H. Expression analysis of dopaminergic neurons in Parkinson's disease and aging links transcriptional dysregulation of energy metabolism to cell death. Acta Neuropathologica 2011, 122(1), 75-86.
  • Khundakar AA, Morris CM, Oakley AE, Thomas AJ. Cellular pathology within the anterior cingulate cortex of patients with late-life depression: A morphometric study. Psychiatry Research: Neuroimaging 2011, 194(2), 184-189.
  • Savy CY, Morris CM, Blain PG, Judge SJ. Behavioural effects of low level exposure to organophosphate pesticides. Toxicology 2011, 290(2-3), 116.
  • Morris CM. Any old iron?. Brain 2011, 134(4), 924-927.
  • Khundakar A, Morris C, Oakley A, Thomas AJ. A morphometric examination of neuronal and glial cell pathology in the orbitofrontal cortex in late-life depression. International Psychogeriatrics 2011, 23(1), 132-140.
  • Morris CM, Ballard CG, Allan L, Rowan E, Stephens S, Firbank MJ, Ford GA, Kenny RA, O'Brien JT, Kalaria RN. NOS3 gene rs1799983 polymorphism and incident dementia in elderly stroke survivors. Neurobiology of Aging 2011, 32(3), 554.e1-554.e6.
  • Reeve AK, Krishnan KJ, Taylor G, Elson JL, Bender A, Taylor RW, Morris CM, Turnbull DM. The low abundance of clonally expanded mitochondrial DNA point mutations in aged substantia nigra neurons. Aging Cell 2009, 8(4), 496-498.
  • Elstner M, Morris C, Heim K, Lichtner P, Bender A, Mehta D, Schulte C, Sharma M, Hudson G, Goldwurm S, Giovanetti A, Zeviani M, Burn D, McKeith I, Perry R, Jaros E, Krüger R, Wichmann H, Schreiber S, Campbell H, Wilson J, Wright A, Dunlop M, Pistis G, Toniolo D, Chinnery P, Gasser T, Klopstock T, Meitinger T, Prokisch H, Turnbull D. Single-cell expression profiling of dopaminergic neurons combined with association analysis identifies pyridoxal kinase as Parkinson's disease gene. Annals of Neurology 2009, 66(6), 792-798.
  • Khundakar A, Morris C, Oakley A, McMeekin W, Thomas AJ. Morphometric analysis of neuronal and glial cell pathology in the dorsolateral prefrontal cortex in late-life depression. British Journal of Psychiatry 2009, 195(2), 163-169.
  • Lane R, He YS, Morris C, Leverenz JB, Emre M, Ballard C. BuChE-K and APOE ε4 allele frequencies in Lewy body dementias, and influence of genotype and hyperhomocysteinemia on cognitive decline. Movement Disorders 2009, 24(3), 392-400.
  • Reeve AK, Krishnan KJ, Elson JL, Morris CM, Bender A, Lightowlers RN, Turnbull DM. Nature of Mitochondrial DNA Deletions in Substantia Nigra Neurons. American Journal of Human Genetics 2008, 82(1), 228-235.
  • Myers AJ, Pittman AM, Zhao AS, Rohrer K, Kaleem M, Marlowe L, Lees A, Leung D, McKeith IG, Perry RH, Morris CM, Trojanowski JQ, Clark C, Karlawish J, Arnold S, Forman MS, Van Deerlin V, de Silva R, Hardy J. The MAPT H1c risk haplotype is associated with increased expression of tau and especially of 4 repeat containing transcripts. Neurobiology of Disease 2007, 25(3), 561-570.
  • Elstner M, Morris C, Prokisch H, Mader M, Klopstock T, Turnbull D. Targeted gene expression analysis in Parkinson's disease and ageing. Journal of Neurology 2007, 254, 108-108.
  • Thomas AJ, Morris C, Davis S, Jackson E, Harrison R, O'Brien JT. Soluble cell adhesion molecules in late-life depression. International Psychogeriatrics 2007, 19(5), 914-920.
  • Hautot D, Pankhurst QA, Morris CM, Curtis A, Burn J, Dobson J. Preliminary observation of elevated levels of nanocrystalline iron oxide in the basal ganglia of neuroferritinopathy patients. Biochimica et Biophysica Acta - Molecular Basis of Disease 2007, 1772(1), 21-25.
  • Oakley AE, Collingwood JF, Dobson J, Love G, Perrott HR, Edwardson JA, Elstner M, Morris CM. Individual dopaminergic neurons show raised iron levels in Parkinson disease. Neurology 2007, 68(21), 1820-1825.
  • Low WC, Junna M, Borjesson-Hanson A, Morris CM, Moss TH, Stevens DL, St Clair D, Mizuno T, Zhang WW, Mykkanen K, Wahlstrom J, Andersen O, Kalimo H, Viitanen M, Kalaria RN. Hereditary multi-infarct dementia of the Swedish type is a novel disorder different from NOTCH3 causing CADASIL. Brain: a journal of neurology 2007, 130, 357-367.
  • De Ferrari GV, Papassotiropoulos A, Biechele T, De-Vrieze FW, Avila ME, Major MB, Myers A, Saez K, Henriquez JP, Zhao A, Wollmer MA, Nitsch RM, Hock C, Morris CM, Hardy J, Moon RT. Common genetic variation within the Low-Density Lipoprotein Receptor-Related Protein 6 and late-onset Alzheimer's disease. Proceedings of the National Academy of Sciences of the USA 2007, 104(22), 9434–9439.
  • Smemo S, Nowotny P, Hinrichs AL, Kauwe JSK, Cherny S, Erickson K, Myers AJ, Kaleem M, Marlowe L, Gibson AM, Hollingworth P, O'Donovan MC, Morris CM, Holmans P, Lovestone S, Morris JC, Thal L, Li Y, Grupe A, Hardy J, Owen MJ, Williams J, Goate A. Ubiquilin 1 polymorphisms are not associated with late-onset Alzheimer's disease. Annals of Neurology 2006, 59(1), 21-26.
  • Lewis H, Beher D, Cookson N, Oakley A, Piggott M, Morris CM, Jaros E, Perry R, Ince P, Kenny RA, Ballard CG, Shearman MS, Kalaria RN. Quantification of Alzheimer pathology in ageing and dementia: age-related accumulation of amyloid-beta(42) peptide in vascular dementia. Neuropathology and Applied Neurobiology 2006, 32(2), 103-118.
  • Bender A, Krishnan KJ, Morris CM, Taylor GA, Reeve AK, Perry RH, Jaros E, Hersheson JS, Betts J, Klopstock T, Taylor RW, Turnbull DM. High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease. Nature Genetics 2006, 38(5), 515-517.
  • Momeni P, Rogaeva E, Van Deerlin V, Yuan WX, Grafman J, Tierney M, Huey E, Bell J, Morris CM, Kalaria RN, van Rensburg SJ, Niehaus D, Potocnik F, Kawarai T, Salehi-Rad S, Sato C, George-Hyslop PS, Hardy J. Genetic variability in CHMP2B and frontotemporal dementia. Neurodegenerative Diseases 2006, 3(3), 129-133.
  • Elson JL, Herrnstadt C, Preston G, Thal L, Morris CM, Edwardson JA, Beal MF, Turnbull DM, Howell N. Does the mitochondrial genome play a role in the etiology of Alzheimer's disease?. Human Genetics 2006, 119(3), 241-254.
  • Price DA, Bassendine MF, Norris SM, Golding C, Toms GL, Schmid ML, Morris CM, Burt AD, Donaldson PT. Apolipoprotein ε3 allele is associated with persistent hepatitis C virus infection. Gut 2006, 55(5), 715-718.
  • Grupe A, Li YH, Rowland C, Nowotny P, Hinrichs AL, Smemo S, Kauwe JSK, Maxwell TJ, Cherny S, Doil L, Tacey K, van Luchene R, Myers A, Vrieze FW, Kaleem M, Hollingworth P, Jehu L, Foy C, Archer N, Hamilton G, Holmans P, Morris CM, Catanese J, Sninsky J, White TJ, Powell J, Hardy J, O'Donovan M, Lovestone S, Jones L, Morris JC, Thal L, Owen M, Williams J, Goate A. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. American Journal of Human Genetics 2006, 78(1), 78-88.
  • Ballard C, Morris C, Kalaria R, McKeith I, Perry R, Perry E. The K variant of the butyrylcholinesterase gene is associated with reduced phosphorylation of tau in dementia patients. Dementia and Geriatric Cognitive Disorders 2005, 19(5-6), 357-360.
  • Myers AJ, Kaleem M, Marlowe L, Pittman AM, Lees AJ, Fung HC, Duckworth J, Leung D, Gibson A, Morris CM, de Silva R, Hardy J. The H1c haplotype at the MAPT locus is associated with Alzheimer's disease. Human Molecular Genetics 2005, 14(16), 2399-2404.
  • Holmes C, Ballard C, Lehmann D, Smith AD, Beaumont H, Day IN, Khan MN, Lovestone S, McCulley M, Morris CM, Munoz DG, O'Brien K, Russ C, Del Ser T, Warden D. Rate of progression of cognitive decline in Alzheimer's disease: effect of butyrylcholinesterase K gene variation. Journal of Neurology, Neurosurgery and Psychiatry 2005, 76(5), 640-643.
  • Gossuin Y, Hautot D, Muller RN, Pankhurst Q, Dobson J, Morris C, Gillis P, Collingwood J. Looking for biogenic magnetite in brain ferritin using NMR relaxometry. NMR in Biomedicine 2005, 18(7), 469-472.
  • Pittman AM, Myers AJ, Abou-Sleiman P, Fung HC, Kaleem M, Marlowe L, Duckworth J, Leung D, Williams D, Kilford L, Thomas N, Morris CM, Dickson D, Wood NW, Hardy J, Lees AJ, de Silva R. Linkage disequilibrium fine mapping and haplotype association analysis of the tau gene in progressive supranuclear palsy and corticobasal degeneration. Journal of Medical Genetics 2005, 42(11), 837-846.
  • Rowan EN, Morris CM, Stephens S, Ballard C, Kalaria RN, McLaren AT, Bradbury M, Rao H, Gibson A, Swainsbury R, Wesnes K, Kenny RA. Impact of Hypertension and Apolipoprotein E4 on Poststroke Cognition in Subjects >75 Years of Age. Stroke 2005, 36(9), 1864-1868.
  • Rowan E, Morris CM, Stephens S, Ballard C, Dickinson H, Rao H, Saxby BK, McLaren AT, Kalaria RN, Kenny RA. Impact of hypertension and apolipoprotein E4 on poststroke cognition in subjects >75 years of age. Stroke 2005, 36(9), 1864-1868.
  • Newton JL, Kerr S, Pairman J, McLaren A, Norton M, Kenny RA, Morris CM. Familial neurocardiogenic (Vasovagal) syncope. American Journal of Medical Genetics 2005, 133(2), 176-179.
  • Newton JL, Kerr S, Pairman J, McLaren A, Norton M, Kenny RA, Morris CM. Familial neurocardiogenic (vasovagal) syncope. American Journal of Medical Genetics: Part A 2005, 133(2), 176-179.
  • Wilson KE, Marouga R, Prime JE, Pashby DP, Orange PR, Crosier S, Keith AB, Lathe R, Mullins J, Estibeiro P, Bergling H, Hawkins E, Morris CM. Comparative proteomic analysis using samples obtained with laser microdissection and saturation dye labelling. Proteomics 2005, 5(15), 3851-3858.
  • Nowotny P, Hinrichs AL, Smemo S, Kauwe JSK, Maxwell T, Holmans P, Hamshere M, Turic D, Jehu L, Hollingworth P, Moore P, Bryden L, Myers A, Doil LM, Tacey KM, Gibson AM, McKeith IG, Perry RH, Morris CM, Thal L, Morris JC, O'Donovan MC, Lovestone S, Grupe A, Hardy J, Owen MJ, Williams J, Goate A. Association studies between risk for late-onset Alzheimer's disease and variants in insulin degrading enzyme. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics 2005, 136(1), 62-68.
  • Vollbach H, Heun R, Morris CM, Edwardson JA, McKeith IG, Jessen F, Schulz A, Maier W, Kolsch H. APOA1 polymorphism influences risk for early-onset nonfamiliar AD. Annals of Neurology 2005, 58(3), 436-441.
  • Newton JL, Donaldson P, Parry S, Kenny RA, Smith J, Gibson AM, Morris C. Angiotensin converting enzyme insertion/deletion polymorphisms in vasovagal syncope. Europace 2005, 7(4), 396-399.
  • Johnson J, Hague SM, Hanson M, Gibson A, Wilson KE, Evans EW, Singleton AA, McInerney-Leo A, Nussbaum RL, Hernandez DG, Gallardo M, McKeith IG, Burn DJ, Ryu M, Hellstrom O, Ravina B, Eerola J, Perry RH, Jaros E, Tienari P, Weiser R, Gwinn-Hardy K, Morris CM, Hardy J, Singleton AB. SNCA multiplication is not a common cause of Parkinson disease or dementia with Lewy bodies. Neurology 2004, 63(3), 554-556.
  • Heckmann JM, Low WC, de Villiers C, Rutherfoord S, Vorster A, Rao H, Morris CM, Ramesar RS, Kalaria RN. Novel presenilin 1 mutation with profound neurofibrillary pathology in an indigenous Southern African family with early-onset Alzheimer's disease. Brain 2004, 127(1), 133-142.
  • Gibson AM, Edwardson JA, Turnbull DM, McKeith IG, Morris CM, Chinnery PF. No evidence of an association between the T16189C mtDNA variant and late onset dementia. Journal of Medical Genetics 2004, 41(1), e7.
  • Margallo-Lana M, Morris CM, Gibson AM, Tan AL, Kay DWK, Tyrer SP, Moore B, Ballard CG. Influence of the amyloid precursor protein locus on dementia in Down syndrome. Neurology 2004, 62(11), 1996-1998.
  • Ballard CG, Morris CM, Rao H, O'Brien JT, Barber R, Stephens S, Rowan E, Gibson A, Kalaria RN, Kenny RA. APOE ε4 and cognitive decline in older stroke patients with early cognitive impairment. Neurology 2004, 63(8), 1399-1402.
  • Yu Wai Man P, Morris CM, Zeviani M, Carrara F, Turnbull DM, Chinnery PF. The role of APOE in the phenotypic expression of Leber hereditary optic neuropathy. Journal of Medical Genetics 2003, 40(4), e41-e41.
  • O'Brien KK, Saxby BK, Ballard CG, Grace J, Harrington F, Ford GA, O'Brien JT, Swan AG, Fairbairn AF, Wesnes K, Del Ser T, Edwardson JA, Morris CM, McKeith IG. Regulation of attention and response to therapy in dementia by butyrylcholinesterase. Pharmacogenetics 2003, 13(4), 231-239.
  • Morris CM, O'Brien KK, Gibson AM, Hardy JA, Singleton AB. Polymorphism in the human DJ-1 gene is not associated with sporadic dementia with Lewy bodies or Parkinson's disease. Neuroscience Letters 2003, 352(2), 151-153.
  • McKeith IG, Burn DJ, Ballard CG, Collerton D, Jaros E, Morris CM, McLaren A, Perry EK, Perry R, Piggott MA, O'Brien JT. Dementia with Lewy bodies. Seminars in Clinical Neuropsychiatry 2003, 8(1), 46-57.
  • Melton LM, Keith AB, Davis S, Oakley AE, Edwardson JA, Morris CM. Chronic glial activation, neurodegeneration, and APP immunoreactive deposits following acute administration of double-stranded RNA. GLIA 2003, 44(1), 1-12.
  • Hussain RI, Ballard CG, Edwardson JA, Morris CM. Transferrin gene polymorphism in Alzheimer's disease and dementia with Lewy bodies in humans. Neuroscience Letters 2002, 317(1), 13-16.
  • de Silva R, Hardy J, Crook J, Khan N, Graham EA, Morris CM, Wood NW, Lees AJ. The tau locus is not significantly associated with pathologically confirmed sporadic Parkinson's disease. Neuroscience Letters 2002, 330(2), 201-203.
  • Bednar I, Paterson D, Marutle A, Pham TM, Svedberg M, Hellstrom-Lindahl E, Mousavi M, Court J, Morris C, Perry E, Mohammed A, Zhang X, Nordberg A. Selective nicotinic receptor consequences in APPSWE transgenic mice. Molecular and Cellular Neuroscience 2002, 20(2), 354-365.
  • Chinnery PF, Curtis AR, Fey C, Jackson MJ, Bates D, Morris CM, Bindoff LA, Coulthard A, Ince PG, Curtis A, Burn J. Neuroferritinopathy. Journal of Neurology, Neurosurgery and Psychiatry 2002, 73(2), 213-213.
  • Singleton AB, Wharton A, O'Brien KK, Walker MP, McKeith IG, Ballard CG, O'Brien J, Perry RH, Ince PG, Edwardson JA, Morris CM. Clinical and neuropathological correlates of apolipoprotein E genotype in dementia with Lewy bodies. Dementia and Geriatric Cognitive Disorders 2002, 14(3-4), 167-175.
  • Kalaria RN, Low WC, Oakley AE, Slade JY, Ince PG, Morris CM, Mizuno T. CADASIL and genetics of cerebral ischaemia. Journal of Neural Transmission: Supplement 2002, (63), 75-90.
  • Ballard C, O'Brien J, Morris CM, Barber R, Swann A, Neill D, McKeith I. The progression of cognitive impairment in dementia with Lewy bodies, vascular dementia and Alzheimer's disease. International Journal of Geriatric Psychiatry 2001, 16(5), 499-503.
  • Khan N, Graham E, Dixon P, Morris C, Mander A, Clayton D, Vaughan J, Quinn N, Lees A, Daniel S, Wood N, de Silva R. Parkinson's disease is not associated with combined alpha-synuclein/apolipoprotein E susceptibility genotype. Annals of Neurology 2001, 49(5), 665-668.
  • Bandopadhyay R, de Silva R, Khan N, Graham E, Vaughan J, Engelender S, Ross C, Morris H, Morris C, Wood NW, Daniel S, Lees A. No pathogenic mutations in the synphilin-1 gene in Parkinson's disease. NEUROSCIENCE LETTERS 2001, 307(2), 125-127.
  • Singleton AB, Gibson AM, McKeith IG, Ballard CG, Edwardson JA, Morris CM. Nitric oxide synthase gene polymorphisms in Alzheimer's disease and dementia with Lewy bodies. Neuroscience Letters 2001, 303(1), 33-36.
  • Curtis ARJ, Fey C, Morris CM, Bindoff LA, Ince PG, Chinnery PF, Coulthard A, Jackson MJ, Jackson AP, McHale DP, Hay D, Barker WA, Markham AF, Bates D, Curtis A, Burn J. Mutation in the gene encoding ferritin light polypeptide causes dominant adult-onset basal ganglia disease. Nature Genetics 2001, 28(4), 350-354.
  • Curtis ARJ, Fey C, Morris CM, Bindoff LA, Ince PG, Chinnery PF, Coulthard A, Jackson MJ, Jackson AP, McHale DP, Hay D, Barker WA, Markham AF, Bates D, Curtis A, Burn J. Mutation in ferritin light chain causes dominant adult onset neurodegeneration. Nature Genetics 2001, 28(4), 350-354.
  • Kalaria RN, Ballard CG, Ince PG, Kenny RA, McKeith IG, Morris CM, O'Brien JT, Perry EK, Perry RH, Edwardson JA. Multiple substrates of late-onset dementia: Implications for brain protection. Ageing Vulnerability: Causes and Interventions: Novartis Foundation Symposium 235 2001, 235, 49-65.
  • Kalaria RN, Ince PG, Kenny RA, McKeith IG, Morris CM, O'Brien JT, Perry EK, Perry RH, Edwardson JA. Multiple substrates of late-onset dementia: implications for brain protection. Ageing Vulnerability: Causes and Interventions: Novartis Foundation Symposium 235 2001, 235, 49-65.
  • Fey C, Curtis ARJ, Chinnery PF, Morris CM, Ince PG, Coulthard A, Jackson MJ, Barker WA, Curtis A, Burn J. A dominant FTL mutation causes a novel and pleiotropic basal ganglia disorder that can mimic torsion-dystonia, Huntington's Disease and parkinsonism. American Journal of Human Genetics 2001, 69(4), 97.
  • Xu WM, Liu LZ, Emson P, Harrington CR, McKeith IG, Perry RH, Morris CM, Charles IG. The CCTTT polymorphism in the NOS2A gene is associated with dementia with Lewy bodies. Neuroreport 2000, 11(2), 297-299.
  • Singleton AB, Hall R, Ballard CG, Perry RH, Xuereb JH, Rubinsztein DC, Tysoe C, Matthews P, Cordell B, Kumar-Singh S, De Jonghe C, Cruts M, van Broeckhoven C, Morris CM. Pathology of early-onset Alzheimer's disease cases bearing the Thr113-114ins presenilin-1 mutation. Brain 2000, 123(12), 2467-2474.
  • Chinnery PF, Taylor GA, Howell N, Andrews RM, Morris CM, Taylor RW, McKeith IG, Perry RH, Edwardson JA, Turnbull DM. Mitochondrial DNA haplogroups and susceptibility to AD and dementia with Lewy bodies. Neurology 2000, 55(2), 302-304.
  • Gibson AM, Singleton AB, Smith G, Woodward R, McKeith IG, Perry RH, Ince PG, Ballard CG, Edwardson JA, Morris CM. Lack of association of the α2-macroglobulin locus on chromosome 12 in AD. Neurology 2000, 54(2), 433-438.
  • Thomas NJ, Morris CM, Scaravilli F, Johansson J, Rossor M, De Lange R, St Clair D, Nicoll J, Blank C, Coulthard A, Bushby K, Ince PG, Burn D, Kalaria RN. Hereditary vascular dementia linked to Notch 3 mutations: CADASIL in British families. Annals of the New York Academy of Sciences 2000, 903, 293-298.
  • Thomas NJ, Morris CM, Scaravilli F, Johansson J, Rossor M, De Lange R, St Clair D, Nicoll J, Blank C, Coulthard A, Bushby K, Ince PG, Burn D, Kalaria RN. Hereditary vascular dementia linked to notch 3 mutations - CADASIL in British families. Annals of the New York Academy of Sciences 2000, 903, 293-298.
  • Thomas AJ, Morris CM, Ferrier IN, Kalaria RN. Distribution of amyloid β42 in relation to the cerebral microvasculature in an elderly cohort with Alzheimer's disease. Annals of the New York Academy of Sciences 2000, 903, 83-88.
  • Thomas AJ, Morris CM, Ferrier IN, Kalaria RN. Distribution of amyloid beta(42) in relation to the cerebral microvasculature in an elderly cohort with Alzheimer's disease. Annals of the New York Academy of Science 2000, 903, 83-88.
  • Twist SJ, Taylor GA, Weddell A, Weightman DR, Edwardson JA, Morris CM. Brain oestradiol and testosterone levels in Alzheimer's disease. Neuroscience Letters 2000, 286(1), 1-4.
  • Leake A, Morris CM, Whateley J. Brain matrix metalloproteinase 1 levels are elevated in Alzheimer's disease. Neuroscience Letters 2000, 291(3), 201-203.
  • Neill D, Curran MD, Middleton D, Mawhinney H, Edwardson JA, Mckeith I, Ballard C, Morris C, Ince P, Jaros E, Perry R. Risk for Alzheimer's disease in older late-onset cases is associated with HLA-DRB1*03. Neuroscience Letters 1999, 275(2), 137-140.
  • Middleton D, Mawhinney H, Curran MD, Edwardson JA, Perry R, McKeith I, Morris C, Ince PG, Neill D. Frequency of HLA-A and B alleles in early and late-onset Alzheimer's disease. Neuroscience Letters 1999, 262(2), 140-142.
  • Atkinson A, Singleton AB, Steward A, Ince PG, Perry RH, McKeith IG, Fairbairn AF, Edwardson JA, Daly AK, Morris CM. CYP2D6 is associated with Parkinson's disease but not with dementia with Lewy Bodies or Alzheimer's disease. Pharmacogenetics and Genomics 1999, 9(1), 31-36.
  • Barber R, Gholkar A, Scheltens P, Ballard C, McKeith IG, Morris CM, O'Brien JT. Apolipoprotein E epsilon 4 allele, temporal lobe atrophy, and white matter lesions in late-life dementias. Archives of Neurology 1999, 56(8), 961-965.
  • Singleton AB, Gibson AM, McKeith IG, Ballard CA, Perry RH, Ince PG, Edwardson JA, Morris CM. alpha(2)-Macroglobulin polymorphisms in Alzheimer's disease and dementia with Lewy bodies. Neuroreport 1999, 10(7), 1507-1510.
  • De Jonghe C, Cruts M, Rogaeva EA, Tysoe C, Singleton A, Vanderstichele H, Meschino W, Dermaut D, Vanderhoeven I, Backhovens H, Vanmechelen E, Morris CM, Hardy J, Rubinsztein DC, St George-Hyslop PH, Van Broeckhoven C. Aberrant splicing in the presenilin-1 intron 4 mutation causes presenile Alzheimer's disease by increased A beta 42 secretion. Human Molecular Genetics 1999, 8(8), 1529-1540.
  • Singleton AB, Smith G, Gibson AM, Woodward R, Perry RH, Ince PG, Edwardson JA, Morris CM. No association between the K variant of the butyrylcholinesterase gene and pathologically confirmed Alzheimer's disease. Human Molecular Genetics 1998, 7(5), 937-939.
  • A. Wozniak, R. E. Hutchison, C. M. Morris and J. B. Hutchison. Neuroblastoma and Alzheimer's disease brain cells contain aromatase activity. Steroids 1998, 63, 263-267.
  • Woodward, R., Singleton, A.B., Gibson, A.M., Edwardson, J.A., Morris, C.M. LRP gene and late-onset Alzheimer's disease. Lancet 1998, 352, 239-240.
  • A. B. Singleton, J. R. Thomson, C. M. Morris, J. A. Court, S. Lloyd and S. Cholerton. Lack of association between the dopamine D2 receptor gene allele DRD2*A1 and cigarette smoking in a United Kingdom population. Pharmacogenetics 1998, 8, 125-128.
  • Court JA, Lloyd S, Thomas N, Piggott MA, Marshall EF, Morris CM, Lamb H, Perry RH, Johnson M, Perry EK. Dopamine and nicotinic receptor binding and the levels of dopamine and homovanillic acid in human brain related to tobacco use. Neuroscience 1998, 87(1), 63-78.
  • Taylor R, Taylor G, Morris C, Edwardson J, Turnbull D. Diagnosis of mitochondrial disease: Assessment of mitochondrial DNA heteroplasmy in blood. Biochemical and Biophysical Research Communications 1998, 251(3), 883-887.
  • Lamb H, Christie J, Singleton AB, Leake A, Perry RH, Ince PG, McKeith IG, Melton LM, Edwardson JA, Morris CM. Apolipoprotein E and alpha-1 antichymotrypsin polymorphism genotyping in Alzheimer's disease and in dementia with Lewy bodies - Distinctions between diseases. Neurology 1998, 50(2), 388-391.
  • Singleton A.B., Atkinson A.M., Gibson A.M., Daly A., Morris C.M. No association between PS-2 polymorphism and AD. Lancet 1997, 350, 336-337.
  • Singleton AB, Lamb H, Leake A, McKeith IG, Perry RH, Morris CM. No association between an intronic polymorphism in the presenilin-1 gene and Alzheimer's disease. Neuroscience Letters 1997, 234(1), 19-22.
  • Singleton AB, Lamb H, Leake A, McKeith IG, Ince PG, Perry RH, Morris CM. No association between a polymorphism in the presenilin 1 gene and dementia with Lewy bodies. NeuroReport 1997, 8(16), 3637-3639.
  • Curran M, Middleton D, Edwardson J, Perry R, McKeith I, Morris C, Neill D. HLA-DR antigens associated with major genetic risk for late-onset Alzheimer's disease. NeuroReport 1997, 8(6), 1467-1469.
  • The APO E and Alzheimer's Disease Meta Analysis Consortium (Morris C.M. - contributing author). Effects of age, sex and ethnicity on the association between apolipoprotein E genotype and Alzheimer's disease. JAMA 1997, 278, 1349-1356.
  • Prasad, S., Thakur, M.K., Morris, C.M., Edwardson, J.A. Effect of 17 beta-estradiol on gene expression in mice brain cortex. Faseb Journal 1997, 11, 1246.
  • Thompson J, Thomas N, Singleton A, Piggott M, Lloyd S, Perry EK, Morris CM, Perry RH, Ferrier IN, Court JA. D2 dopamine receptor gene (DRD2) Taq1 A polymorphism: reduced dopamine D2 receptor binding in the human striatum associated with the A1 allele. Pharmacogenetics 1997, 7(6), 479-484.
  • C. Ballard, H. Massey, H. Lamb and C. Morris. Apolipoprotein E: non-cognitive symptoms and cognitive decline in late onset Alzheimer's disease. Journal of Neurology Neurosurgery and Psychiatry 1997, 63, 273-274.
  • Neill, D., Leake, A., Hughes, D., Keith, A.B., Taylor, G.A., Allsop, D., Rima, B.K., Morris, C., Candy, J.M., Edwardson, J.A. Effect of aluminium on expression and processing of amyloid precursor protein. Journal of Neuroscience Research 1996, 46, 395-403.
  • Christie J, Lamb H, Singleton AB, Leake A, Melton LS, Perry RH, McKeith IG, Morris CM. Determination of the alpha-1 anti-chymotrypsin polymorphism in Alzheimer's disease. Alzheimer's Research 1996, 2, 201-204.
  • Benjamin, R., Leake, A., McArthur, F.K., Candy, J.M., Ince, P.G., Edwardson, J.A., Torvik, A., Morris, C.M., Bjertness, E. Apolipoprotein E genotype and Alzheimer's disease in an elderly Norwegian cohort. Neurodegeneration 1996, 5, 43-47.
  • Court JA, Perry EK, Spurden D, Griffiths M, Kerwin JM, Morris CM, Johnson M, Oakley AE, Birdsall NJM, Clementi F, Perry RH. The role of the cholinergic system in the development of the human cerebellum. Developmental Brain Research 1995, 90(1-2), 159-167.
  • Benjamin R, Leake A, Ince PG, Perry RH, McKeith IG, Edwardson JA, Morris CM. Effects of apolipoprotein E genotype on cortical neuropathology in senile dementia of the Lewy body and Alzheimer's disease. Neurodegeneration 1995, 4(4), 443-448.
  • Morris, C.M., Benjamin, R., Leake, A., McArthur, F.K., Candy, J.M., Ince, P.G., Torvik, A., Bjertness, E., Edwardson, J.A. Effect of apolipoprotein E genotype on Alzheimer's disease neuropathology in a cohort of elderly Norwegians. Neuroscience Letters 1995, 201, 45-48.
  • Perry EK, Morris CM, Court JA, Cheng A, Fairbairn AF, McKeith IG, Irving D, Brown A, Perry RH. Alteration in nicotine binding sites in Parkinson's disease, Lewy body dementia and Alzheimer's disease: Possible index of early neuropathology. Neuroscience 1995, 64(2), 385-395.
  • Benjamin R, Leake A, Edwardson JA, McKeith IG, Ince PG, Perry RH, Morris CM. Apolipoprotein E genes in Lewy body and Parkinson's disease. Lancet 1994, 343(8912), 1565-1565.
  • Kerwin JM, Morris CM, Johnson M, Perry RH, Perry EK. Hippocampal p75 Nerve Growth Factor Receptor Immunoreactivity in Development, Normal Aging and Senescence. Acta Anatomica 1993, 147(4), 216-222.
  • Perry EK, Irving D, Kerwin JM, McKeith IG, Thompson P, Collerton D, Fairbairn AF, Ince PG, Morris CM, Cheng AV, Perry RH. Cholinergic Transmitter and Neurotrophic Activities in Lewy Body Dementia: Similarity to Parkinson's and Distinction from Alzheimer Disease. Alzheimer Disease & Associated Disorders 1993, 7(2), 69-79.
  • Perry EK, Court JA, Johnson M, Smith CJ, James V, Cheng AV, Kerwin JM, Morris CM, Piggott MA, Edwardson JA, Birdsall NJM, Turner JT, Perry RH. Autoradiographic comparison of cholinergic and other transmitter receptors in the normal human hippocampus. Hippocampus 1993, 3(3), 307-315.
  • Kerwin JM, Morris CM, Perry RH, Perry EK. Nerve Growth Factor Receptor-Like Immunoreactivity in the Human Spinal Cord. Acta Anatomica 1992, 144(4), 348-353.
  • Dedman DJ, Treffry A, Candy JM, Taylor GAA, Morris CM, Bloxham CA, Perry RH, Edwardson JA, Harrison PM. Iron and aluminium in relation to brain ferritin in normal individuals and Alzheimer's-disease and chronic renal-dialysis patients. Biochemical Journal 1992, 287, 509-514.
  • Kerwin JM, Morris CM, Perry RH, Perry EK. Hippocampal nerve growth factor receptor immunoreactivity in patients with Alzheimer's and Parkinson's disease. Neuroscience Letters 1992, 143(1-2), 101-104.
  • Cheng AVT, Ferrier IN, Morris CM, Jabeen S, Sahgal A, McKeith IG, Edwardson JA, Perry RH, Perry EK. Cortical serotonin-S₂ receptor binding in Lewy body dementia, Alzheimer's and Parkinson's diseases. Journal of the Neurological Sciences 1991, 106(1), 50-55.

• Book Chapters

  • Morris CM, Savy C, Judge SJ, Blain PG. Acute toxicity of organophosphorus compounds. In: Basic and Clinical Toxicology of Organophosphorus Compounds. London: Springer-Verlag London Ltd, 2014, pp.45-78.
  • Keogh MJ, Morris CM, Chinnery PF. Neuroferritinopathy. In: Kailash P. Bhatia and Susanne A. Schneider, ed. Metal Related Neurodegenerative Disease. London: Academic Press, 2013, pp.91-123.
  • Kalaria RN, Cookson NJ, Mizuno T, Oakley A, Singleton AB, Morris CM, Coulthard A, Blank SC, Bushby KMD, Nicoll J, De Lange RPJ, Burn DJ, St Clair D. Microvascular pathology in familial multi-infarct dementia or CADASIL: implications for cerebral blood flow. In: Fukuuchi, Y; Tomita, M; Koto, A, ed. Ischemic Blood Flow in the Brain. Tokyo, New York: Springer, 2000, pp.431-442.

• Letter

  • Robinson AC, Palmer L, Love S, Hamard M, Esiri M, Ansorge O, Lett D, Attems J, Morris C, Troakes C, Selvackadunco S, King A, Al-Sarraj S, Mann DMA. Extended post-mortem delay times should not be viewed as a deterrent to the scientific investigation of human brain tissue: a study from the Brains for Dementia Research Network Neuropathology Study Group, UK. Acta Neuropathologica 2016, 132(5), 753-755.

• Note

  • van der Lee SJ, Conway OJ, Jansen I, Carrasquillo MM, Kleineidam L, van den Akker E, Hernandez I, van Eijk KR, Stringa N, Chen JA, Zettergren A, Andlauer TFM, Diez-Fairen M, Simon-Sanchez J, Lleo A, Zetterberg H, Nygaard M, Blauwendraat C, Savage JE, Mengel-From J, Moreno-Grau S, Wagner M, Fortea J, Keogh MJ, Blennow K, Skoog I, Friese MA, Pletnikova O, Zulaica M, Lage C, de Rojas I, Riedel-Heller S, Illan-Gala I, Wei W, Jeune B, Orellana A, Then Bergh F, Wang X, Hulsman M, Beker N, Tesi N, Morris CM, Indakoetxea B, Collij LE, Scherer M, Morenas-Rodriguez E, Ironside JW, van Berckel BNM, Alcolea D, Wiendl H, Strickland SL, Pastor P, Rodriguez Rodriguez E, Mead S, Synofzik M, van Swieten JC, Leber I, Ferrari R, Hernandez DG, Nalls MA, Rohrer JD, Ramasamy A, Kwok JBJ, Dobson-Stone C, Schofield PR, Halliday GM, Hodges JR, Piguet O, Bartley L, Thompson E, Borroni B, Padovani A, Cruchaga C, Cairns NJ, Benussi L, Binetti G, Ghidoni R, Forloni G, Albani D, Galimberti D, Fenoglio C, Serpente M, Scarpini E, Blesa R, Landqvist Waldo M, Nilsson K, Nilsson C, Mackenzie IRA, Hsiung G-YR, Mann DMA, Grafman J, Morris CM, Attems J, Griffiths TD, McKeith IG, Thomas AJ, Pietrini P, Huey ED, Wassermann EM, Baborie A, Jaros E, Tierney MC, Razquin C, Ortega-Cubero S, Alonso E, Perneczky R, Diehl-Schmid J, Alexopoulos P, Kurz A, Rainero I, Rubino E, Pinessi L, Rogaeva E, St George-Hyslop P, Rossi G, Tagliavini F, Giaccone G, Rowe JB, Schlachetzki JCM, Uphill J, Collinge J, Danek A, Van Deerlin VM, Grossman M, Trojanowski JQ, van der Zee J, Van Broeckhoven C, Cappa SF, Hannequin D, Golfier V, Vercelletto M, Brice A, Nacmias B, Sorbi S, Bagnoli S, Piaceri I, Nielsen JE, Hjermind LE, Riemenschneider M, Mayhaus M, Ibach B, Gasparoni G, Pichler S, Gu W, Rossor MN, Fox NC, Warren JD, Spillantini MG, Morris HR, Rizzu P, Snowden JS, Rollinson S, Richardson A, Gerhard A, Bruni AC, Maletta R, Frangipane F, Cupidi C, Bernardi L, Anfossi M, Gallo M, Conidi ME, Smirne N, Baker M, Josephs KA, Parisi JE, Seeley WW, Miller BL, Karydas AM, Rosen H, Dopper EGP, Seelaar H, Logroscino G, Capozzo R, Novelli V, Puca AA, Franceschi M, Postiglione A, Milan G, Sorrentino P, Kristiansen M, Chiang H-H, Graff C, Pasquier F, Rollin A, Deramecourt V, Lebouvier T, Kapogiannis D, Ferrucci L, Pickering-Brown S, Singleton AB, Hardy J, Momeni P, Boeve BF, Petersen RC, Ferman TJ, van Gerpen JA, Reinders MJT, Uitti RJ, Tarraga L, Maier W, Dols-Icardo O, Kawalia A, Dalmasso MC, Boada M, Zettl UK, van Schoor NM, Beekman M, Allen M, Masliah E, de Munain AL, Pantelyat A, Wszolek ZK, Ross OA, Dickson DW, Graff-Radford NR, Knopman D, Rademakers R, Lemstra AW, Pijnenburg YAL, Scheltens P, Gasser T, Chinnery PF, Hemmer B, Huisman MA, Troncoso J, Moreno F, Nohr EA, Sorensen TIA, Heutink P, Sanchez-Juan P, Posthuma D, Coppola G, Karydas AM, Varpetian A, Foroud TM, Levey AI, Kukull WA, Mendez MF, Ringman J, Chui H, Cotman C, DeCarli C, Miller BL, Geschwind DH, Clarimon J, Christensen K, Ertekin-Taner N, Scholz SW, Ramirez A, Ruiz A, Slagboom E, van der Flier WM, Holstege H. Correction to: A nonsynonymous mutation in PLCG₂ reduces the risk of Alzheimer’s disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity. Acta Neuropathologica 2020, 139, 959-962.

• Review

  • Ward TH, Gilbert DC, Higginbotham G, Morris CM, Speirs V, Curtin NJ. Radiotherapy biobanking: current landscape, opportunities, challenges, and future aspirations. Journal of Pathology: Clinical Research 2022, 8(1), 3-13.