Staff Profile
Dr Niall Kenneth
IRES Fellow
- Email: niall.kenneth@ncl.ac.uk
- Telephone: 0191 2085096
- Address: Institute for Cell and Molecular Biosciences, Level 2, Cookson Building,
Medical School
University of Newcastle
Framlington Place
Newcastle upon Tyne,
NE2 4HH
Background
Current research interests: Click here.
Google Scholar: Click here.
Publications
- Carroll B, Otten E, Manni D, Stefanatos R, Menzies F, Smith G, Jurk D, Kenneth N, Wilkinson S, Passos J, Attems J, Veal E, Teyssou E, Seilhean D, Millecamps S, Eskelinen E-L, Bronowska A, Rubinsztein DC, Sanz A, Korolchuk V. Oxidation of SQSTM1/p62 mediates the link between redox state and protein homeostasis. Nature Communications 2018, 9, 256.
- Ivanova IG, Park CV, Yemm AI, Kenneth NS. PERK/eIF2α signaling inhibits HIF-induced gene expression during the unfolded protein response via YB1-dependent regulation of HIF1α translation. Nucleic Acids Research 2018, 46(8), 3878-3890.
- Park CV, Ivanova IG, Kenneth NS. XIAP upregulates expression of HIF target genes by targeting HIF1α for Lys63-linked polyubiquitination. Nucleic Acids Research 2017, 45(16), 9336-9347.
- Kenneth NS, Hucks GE, Kocab AJ, McCollom AL, Duckett CS. Copper is a potent inhibitor of both the canonical and non-canonical NFκB pathways. Cell Cycle 2014, 13(6), 1006-1014.
- Kenneth NS, Mudie S, Naron S, Rocha S. TfR1 interacts with the IKK complex and is involved in IKK-NF-κB signalling. Biochemical Journal 2013, 449(1), 275-284.
- Kenneth NS, Younger JM, Hughes ED, Marcotte D, Barker PA, Saunders TL, Duckett CS. An inactivating caspase 11 passenger mutation originating from the 129 murine strain in mice targeted for c-IAP1. Biochemical Journal 2012, 443(2), 355-359.
- Fairley JA, Mitchell LE, Berg T, Kenneth NS, von Schubert C, Silljé HH, Medema RH, Nigg EA, White RJ. Direct regulation of tRNA and 5S rRNA gene transcription by Polo-like kinase 1. Molecular Cell 2012, 45(4), 541-552.
- Kenneth NS, Duckett CS. IAP proteins: regulators of cell migration and development. Current Opinion in Cell Biology 2012, 24(6), 871-875.
- van Uden P, Kenneth NS, Webster R, Müller H, Mudie S, Rocha S. Evolutionary conserved regulation of HIF-1β by NF-κB. PLoS Genetics 2011, 7, e1001285.
- Newton IP, Kenneth NS, Appleton PL, Näthke I, Rocha S. Adenomatous Polyposis Coli and Hypoxia-inducible Factor-1α have an Antagonistic Connection. Molecular Biology of the Cell 2010, 21(21), 3630-3638.
- Kenneth NS, Mudie S, Rocha S. IKK and NF-kappaB-mediated regulation of Claspin impacts on ATR checkpoint function. EMBO J 2010, 29, 2966-78.
- Kenneth NS, White RJ. Regulation by c-Myc of ncRNA expression. Curr Opin Genet Dev 2009, 19, 38-43.
- Kenneth NS, Mudie S, vanUden P, Rocha S. SWI/SNF regulates the cellular response to hypoxia. J Biol Chem 2009, 284, 4123-31.
- Kenneth NS, Marshall L, White RJ. Recruitment of RNA polymerase III in vivo. Nucleic Acids Res 2008, 36, 3757-3764.
- Kenneth NS, Rocha S. Regulation of gene expression by hypoxia. Biochem J 2008, 414, 19-29.
- vanUden P, Kenneth NS, Rocha S. Regulation of hypoxia-inducible factor-1alpha by NF-kappaB. Biochem J 2008, 412, 477-484.
- Kenneth NS, Ramsbottom BA, Gomez-Roman N, Marshall L, Cole PA, White RJ. TRRAP and GCN5 are used by c-Myc to activate RNA polymerase III transcription. Proc Natl Acad Sci U S A 2007, 104, 14917-22.
- Gomez-Roman N, Felton-Edkins ZA, Kenneth NS, Goodfellow SJ, Athineos D, Zhang J, Ramsbottom BA, Innes F, Kantidakis T, Kerr ER, Brodie J, Grandori C, White RJ. Activation by c-Myc of transcription by RNA polymerases I, II and III. Biochem Soc Symp 2006, 73, 141-154.
- Ernens I, Goodfellow SJ, Innes F, Kenneth NS, Derblay LE, White RJ, Scott PH. Hypoxic stress suppresses RNA polymerase III recruitment and tRNA gene transcription in cardiomyocytes. Nucleic Acids Res 2006, 34, 286-294.
- Fairley JA, Kantidakis T, Kenneth NS, Intine RV, Maraia RJ, White RJ. Human La is found at RNA polymerase III-transcribed genes in vivo. Proc Natl Acad Sci U S A 2005, 102, 18350-5.