Group Members
Julie Errington
Clinical Trials Analyst/Coordinator
- Telephone: +44 (0) 191 208 4357
- Personal Website: https://www.nccpg.org/
- Address: Newcastle University Centre for Cancer
Paul O'Gorman Building
Medical School
Framlington Place
Newcastle upon Tyne
NE2 4HH
Background
Current role
Management and coordination of paediatric cancer clinical trials according to the principles of GCP.
Analysis of clinical trial samples using HPLC, LC/MS/MS, ELISA & AAS.
First Aider & Fire Marshall for the Paul O'Gorman building
Research
Clinical trials in paediatric cancer - CTIMP's and non CTIMPs (specialising in pharmacokinetics, pharmacogenetics & pharmacodynamics).
Over 20 years experience in clinical trials.
Publications
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Articles
- Veal GJ, Tweddle DA, Visser J, Errington J, Buck H, Marange J, Moss J, Joseph S, Mulla H. Pharmacokinetics and safety of a novel oral liquid formulation of 13-cis retinoic acid in children with neuroblastoma: A randomized crossover clinical trial. Cancers 2021, 13(8), 1868.
- Barnett S, Errington J, Sludden J, Jamieson D, Poinsignon V, Paci A, Veal GJ. Pharmacokinetics and pharmacogenetics of cyclophosphamide in a neonate and infant childhood cancer patient population. Pharmaceuticals 2021, 14(3), 272.
- Gowland C, Berry P, Errington J, Jeffrey P, Bennett G, Godfrey L, Pittman M, Niewiarowski A, Symeonides SN, Veal GJ. Development of a LC-MS/MS method for the quantification of toxic payload DM1 cleaved from BT1718 in a Phase I study. Bioanalysis 2021, 13(2), 101-113.
- Hawley J, Veal GJ, Errington J, McDonald LG, Tweddle DA. The use of pharmacokinetically guided carboplatin chemotherapy in a pre-term infant with neuroblastoma-associated spinal cord compression. Pediatric Blood and Cancer 2019, 66(9), 1-3.
- Duong JK, Veal GJ, Nath CE, Shaw PJ, Errington J, Ladenstein R, Boddy AV. Population pharmacokinetics of carboplatin, etoposide and melphalan in children: A re-evaluation of paediatric dosing formulas for carboplatin in patients with normal or mild impairment of renal function. British Journal of Clinical Pharmacology 2019, 85(1), 136-146.
- Jackson RK, Liebich M, Berry P, Errington J, Liu J, Parker C, Moppett J, Samarasinghe S, Hough R, Rowntree C, Goulden NJ, Vora A, Kearns PR, Saha V, Hempel G, Irving JAE, Veal GJ. Impact of dose and duration of therapy on dexamethasone pharmacokinetics in childhood acute lymphoblastic leukaemia - a report from the UKALL 2011 trial. European Journal of Cancer 2019, 120, 75-85.
- Errington J, Malik G, Evans J, Baston J, Parry A, Price L, Johnstone H, Peters S, Oram V, Howe K, Whiteley E, Tunnacliffe J, Veal GJ. Investigating the Experiences of Childhood Cancer Patients and Parents Participating in Optional Nontherapeutic Clinical Research Studies in the UK. Pediatric Blood & Cancer 2016, 63(7), 1193-1197.
- Veal GJ, Cole M, Chinnaswamy G, Sludden J, Jamieson D, Errington J, Malik G, Hill CR, Chamberlain T, Boddy AV. Cyclophosphamide pharmacokinetics and pharmacogenetics in children with B-cell non-Hodgkin’s lymphoma. European Journal of Cancer 2016, 55, 56–64.
- Veal GJ, Errington J, Sastry J, Chisholm J, Brock P, Morgenstern D, Pritchard-Jones K, Chowdhury T. Adaptive dosing of anticancer drugs in neonates – facilitating evidence-based dosing regimens. Cancer Chemotherapy and Pharmacology 2016, 77(4), 685-692.
- Veal GJ, Errington J, Hayden J, Hobin D, Murphy D, Dommett RM, Tweddle DA, Jenkinson H, Picton S. Carboplatin therapeutic monitoring in preterm and full-term neonates. European Journal of Cancer 2015, 51(14), 2022-2030.
- Hill CR, Cole M, Errington J, Malik G, Boddy AV, Veal GJ. Characterisation of the clinical pharmacokinetics of actinomycin D and the influence of ABCB1 pharmacogenetic variation on actinomycin D disposition in children with cancer. Clinical Pharmacokinetics 2014, 53(8), 741-751.
- Veal GJ, Errington J, Rowbotham SE, Illingworth NA, Malik G, Cole M, Daly AK, Pearson ADJ, Boddy AV. Adaptive dosing approaches to the individualization of 13-cis-retinoic acid (isotretinoin) treatment for children with high-risk neuroblastoma. Clinical Cancer Research 2013, 19(2), 469-479.
- Chinnaswamy G, Errington J, Foot A, Boddy AV, Veal GJ, Cole M. Pharmacokinetics of cyclophosphamide and its metabolites in pediatric patients receiving high-dose myeloablative therapy. European Journal of Cancer 2011, 47(10), 1556-1563.
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Conference Proceedings (inc. Abstracts)
- Veal G, Errington J, Hayden J, Hobin D, Murphy D, Dommett R, Tweddle D, Jenkinson H, Picton S. Therapeutic drug monitoring approaches to the treatment of preterm and full-term neonates with cancer - A UK experience. In: 47th Congress of the International Society of Paediatric Oncology (SIOP). 2015, Cape Town, South Africa: Wiley-Blackwell.
- Veal GJ, Errington J, Hayden J, Hobin D, Murphy D, Dommett RA, Tweddle DA, Jenkinson H, Picton S. Carboplatin therapeutic monitoring in preterm and full-term neonates. In: AACR 106th Annual Meeting 2015. 2015, Philadelphia, PA, USA: AACR.
- Veal GJ, Errington J, Malik G, Hill CR, Boddy AV. Investigating the pharmacokinetics and dosing of anticancer drugs in infants and young children. In: 2013 ASCO Annual Meeting. 2013, Chicago, Illinois, USA: American Society of Clinical Oncology.
- Chinnaswamy G, Errington J, Foot A, Boddy AV, Veal GJ, Cole M. Pharmacokinetics of high-dose cyclophosphamide and its metabolites in paediatric patients. In: Pediatric Blood & Cancer: 43rd Congress of the International Society of Paediatric Oncology (SIOP). 2011, Auckland, New Zealand: John Wiley & Sons, Inc.
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Letter
- Geurten C, Errington J, Barnett S, Patel H, Noor S, Saraff V, Veal GJ, Gatz SA. Spontaneous fractures during 13-cis retinoic acid therapy for neuroblastoma. Pediatric Blood and Cancer 2023, 70(9), e30430.