Research

Oral cancer research. Early detection of squamous cell carcinoma(OSCC) using brush biopsy technique (cytobrush) which can be used as adjunctive not substitute to incisional biopsy .

Evaluation the expression level of  NOTCH signal and a novel biomarker Epein3 in oral precancerous lesion (OPL) and OSCC. Different OSCC cell lines and Formalin-Fixed Paraffin Embedded (FFPE)  tissue samples of OPL and OSCC were used.

Publications

• Articles

  • Tian X, Teo WFA, Yang Y, Dong L, Wong A, Chen L, Ahmed H, Choo SW, Jakubovics NS, Tan GYA. Genome characterisation and comparative analysis of Schaalia dentiphila sp. nov. and its subspecies, S. dentiphila subsp. denticola subsp. nov., from the human oral cavity. BMC Microbiology 2024, 24(1), 185.
  • Tian X, Teo WFA, Wee WY, Yang Y, Ahmed H, Jakubovics NS, Choo SW, Tan GYA. Genome characterization and taxonomy of Actinomyces acetigenes sp. nov., and Actinomyces stomatis sp. nov., previously isolated from the human oral cavity. BMC Genomics 2023, 24(1), 734.
  • Ahmed H, Paterson I, Aziz SA, Cremona O, Robinson M, Carrozzo M, Valentine RA. Expression of Epsin3 and its interaction with Notch signalling in oral epithelial dysplasia and oral squamous cell carcinoma. Journal of Oral Pathology and Medicine 2023, 52(8), 710-717.
  • Rostami N, Shield RC, Serrage H, Lawler C, Brittan JL, Yassin S, Ahmed H, Treumann A, Thompson P, Waldron K, Nobbs A, Jakubovics N. Interspecies competition in oral biofilms mediated by Streptococcus gordonii extracellular deoxyribonuclease SsnA. npj Biofilms and Microbiomes 2022, 8(1), 96.
  • Choo SW, Mohammed WK, Mutha NVR, Rostami N, Ahmed H, Krasnogor N, Tan GYA, Jakubovics NS. Transcriptomic Responses to Coaggregation between Streptococcus gordonii and Streptococcus oralis. Applied and Environmental Microbiology 2021, 87(22), e01558-21.