Staff Profile

I am the Production Manager for the PET Tracer Production Unit at Newcastle University. We are part of the Imaging Hub for the Faculty of Medical Sciences (formerly the Centre for InVivo Imaging) 

My role is to deliver a diagnostic imaging service to University and NHS colleagues in the North East.

Qualifications

PhD Synthetic Organic Chemistry - University of Glasgow 

BSc (Hons) Biological Chemistry - University of Dundee

Previous Positions

2009-2013 Research Associate, Newcastle University - Radiochemistry & Flow Chemistry 

2013-2017 Research Associate, Newcastle University - Medicinal Chemistry and drug discovery

• Miller DC, Martin MP, Adhikari S, Brennan A, Endicott JA, Golding BT, Hardcastle IR, Heptinstall A, Hobson S, Jennings C, Molyneux L, Ng Y, Wedge SR, Noble MEM, Cano C. Identification of a novel ligand for the ATAD2 bromodomain with selectivity over BRD4 through a fragment growing approach. Organic and Biomolecular Chemistry 2018, 16(11), 1843-1850.
• Doherty S, Knight JG, Carroll MA, Ellison JR, Hobson SJ, Stevens S, Hardacre C, Goodrich P. Efficient and selective hydrogen peroxide-mediated oxidation of sulfides in batch and segmented and continuous flow using a peroxometalate-based polymer immobilised ionic liquid phase catalyst. Green Chemistry 2015, 17(3), 1559-1571.
• Carroll MA, Launay GG, Reed CD, Hobson SJ. Evaluation of tetraethylammonium bicarbonate as a phase transfer agent in the formation of [F-18]fluoroarenes in a microreactor. In: Journal of Labelled Compounds and Radiopharmaceuticals: 19th International Symposium on Radiopharmaceutical Sciences. 2011, Amsterdam, Netherlands: John Wiley & Sons Ltd.
• Spry C, Sewell AL, Hering Y, Villa MVJ, Weber J, Hobson SJ, Harnor SJ, Gul S, Marquez R, Saliba KJ. Structure-activity Analysis of CJ-15,801 Analogues That Interact With Plasmodium Falciparum Pantothenate Kinase and Inhibit Parasite Proliferation. European Journal of Medicinal Chemistry 2018, 143, 1139-1147.
• Hobson SJ, Parkin A, Marquez R. Oxidative Rearrangements of Isobenzofurans: Studies toward the Synthesis of the Ajudazols. Organic Letters 2008, 10, 2813-2816.
• Hobson SJ, Marquez R. Stereocontrolled synthesis of highly functionalised spirocyclic pyrans. Organic & Biomolecular Chemistry 2006, 4, 3808-3814.
• Al-Khawaldeh I, Aldred GG, Alyassiri M, Basmadjian C, Bordoni C, Harnor SJ, Heptinstall AB, Hobson SJ, Jennings CE, Khalifa S, Lebraud H, Miller DC, Shrives HJ, de Souza JV, Stewart HL, Temple M, Totobenazara J, Tucker JA, Tudhope SJ, Wang LZ, Bronowska AK, Cano C, Endicott JA, Golding BT, Hardcastle IR, Hickson I, Wedge SR, Willmore E, Noble MEM, Waring MJ. An alkynylpyrimidine-based covalent inhibitor that targets a unique cysteine in NF-κB-inducing kinase (NIK). Journal of Medicinal Chemistry 2021, 64(14), 10001-10018.
• Chessari G, Hardcastle IR, Ahn JS, Anil B, Anscome E, Bawn RH, Bevan LD, Blackburn TJ, Buck I, Cano C, Carbain B, Castro J, Cons B, Cully SJ, St Denis J, Endicott JA, Fazal L, Golding BT, Griffin RJ, Haggerty K, Harnor S, Hearn K, Hobson S, Holvey RS, Howard S, Jennings C, Johnson CN, Lunec J, Miller DC, Newell DR, Noble MEM, Reeks J, Revill CH, Riedinger C, Tamanini E, Thomas H, Thompson NT, Vinkovic M, Wedge SR, Williams PA, Wilsher N, Zhang B, Zhao Y. Structure-Based Design of Potent and Orally Active Isoindolinone Inhibitors of MDM2-p53 Protein–Protein Interaction. Journal of Medicinal Chemistry 2021, 64(7), 4071-4088.