Background

VACANCIES - We are always open to informal enquiries for PhD or Post-doctoral positions in this lab, and often find a way to fund good candidates. Please feel free to email me if you are interested (jeff.errington@ncl.ac.uk ).  

Senior Research Associates

Dr Yoshikazu Kawai, Wellcome Trust Postdoctoral Fellow
Dr Ling Juan Wu, Wellcome Trust Postdoctoral Fellow

Postdoctoral Research Fellows

Dr Yousef Dashti, Visiting Postdoctoral Fellow
Dr Kaveh Emami, Wellcome Trust Postdoctoral Fellow
Dr David Roberts, Wellcome Trust Postdoctoral Fellow
Dr Andrew Watson, Wellcome Trust Postdoctoral Fellow

Graduate Students

Jonathan Chapman, MRC CASE Studentship
Felaine Sumang, DOST-SEI Foreign Graduate Scholarship Program, Philippines
Mary Salliss, University Graduate Studentship 

Research Technicians

Ms Fran Davison
Dr Maki Kawai 

Appointments, honours and awards

2018-23 2nd Wellcome Senior Investigator Award
2018 Edmond de Rothschild Lecture, l'Institut de Biologie Physico-Chimique, Paris
2017 12th Memorial Lecture "David Vazquez", CBM, Madrid
2017 Lwoff Award and Medal, Federation of European Microbiological Societies
2015 Elected to the European Academy of Microbiology
2015 Jean Shanks Lecture, UK Academy of Medical Sciences
2015-20 2nd European Research Council Advanced Investigator Grant
2015 Leeuwenhoek Lecture, Prize and Medal of the Royal Society
2015-17 Chair of the Wellcome Trust Expert Review Group; Molecular Basis of Cell Function
2014 20th Anniversary Medal and Prize, BBSRC
2014 Novartis Medal and Prize, UK Biochemical Society
2013- Co-Director, Newcastle University Centre for Synthetic Biology and Bioexploitation
2012-18 Wellcome Senior Investigator Award
2012 BBSRC Health portfolio Working Group
2011 8th Sir William Dunn Lecture, Cambridge
2011 Mendel Lecture, Brno, Czech Republic
2010 European Research Council Advanced Investigator Grant
2010-2013 Director Biota Pharmaceuticals Inc (NASDAQ)
2009 Inaugural Joel Mandelstam Memorial Lecture, University of Oxford
2009 Fred Griffith Prize Review Lecture, Society for General Microbiology
2009- Editorial Board EMBO Journal, EMBO Reports
2008 Co-Chair Gordon Conference on Bacterial Cell Surfaces
2008 Kluyver Lecture of the Dutch Microbiological Society
2007- Founder, Director, Chairman, Demuris Ltd
2007 Highly Cited status on ISI Web of Science
2007-2009 Council of the Royal Society
2007 Elected to the American Academy of Microbiology
2007 Elected Fellow of the Academy of Medical Science
2006-2009 Panel member of the Wellcome Trust Molecules, Genes and Cells Committee
2006 Co-Chair Gordon Conference on "Bacterial Cell Surfaces", USA
2005 Co-organiser 2nd ASM / SGM Conference on "Prokaryotic Development", Vancouver
2005-2012 Director of the Institute for Cell and Molecular Biosciences, Newcastle University
2005 Krampitz Lecture (USA)
2004 Elected to EMBO
2003 Elected Fellow of the Royal Society
2002 Co-organiser Juan March Foundation Workshop “Bacterial Cell Division”; Madrid
2002-2005 Elected Council Member, Society for General Microbiology
2002 Nordström Lecture (Sweden)
2001 Franco Tatò Memorial Lecture (Italy)
2000-2003 Genes and Developmental Biology Committee, BBSRC.
1998- Editorial Board, Current Opinion in Microbiology.
1998 Co-organiser of Colloquium for the American Society for Microbiology.
1999- Trustee to the EPA Cephalosporin Research Fund, Oxford.
1998-2009 Scientific Founder, Director and Chief Scientific Officer, Prolysis Ltd, Oxford.
1997-2002 BBSRC Senior (Professorial) Research Fellowship, Oxford.
1997 Awarded title of Professor of Microbiology, Oxford.
1996 Co-Organiser 44th Harden Conference of the Biochemical Society.
1996- Editorial Board, Molecular Microbiology.
1993-1994 Visiting Scholar, Biochemistry Department, University of Sydney, Australia.
1993-1994 Cell Committment and Differentiation Initiative Steering group, BBSRC.
1992-1994 Editorial Board, Journal of Bacteriology.
1990-1993 Molecular Biology and Genetics Subcommittee, SERC.
1990-1993 Genetics and Molecular Biology Group, Society for General Microbiology.
1985 Awarded Royal Society University Research Fellowship, Oxford.
1977 John Corran Prize for outstanding undergraduate work in genetics.

Funding

Work in the lab is presently supported mainly by a Wellcome Trust Senior Investigator Award. Several students and post-docs have been supported directly by Long Term Fellowships from EMBO and the EU Marie-Curie scheme.

Industrial Relevance

Early work from the Errington lab was exploited through a spin-out company Prolysis Ltd, which was acquired by an international anti-infectives company Biota Pharmaceuticals Inc.

A Newcastle University spin out company Demuris Ltd (www.Demuris.co.uk) was established in 2008 to exploit drug antibiotic screening opportunities emerging from the Errington lab.

Patents

Several patents have been filed or granted on antibiotic screening methods and new antibiotic compounds. 

Research

Research Interests

Bacterial cell biology, antibiotic discovery, synthetic biology and infectious disease

Cell division, chromosome segregation, and the control of cell shape are some of the most fundamental problems in biology. This lab uses an array of biochemical, genetic and microscopic methods to study these problems in a range of bacteria, including important pathogens.

We also collaborate with Demuris Ltd, an antibiotic discovery company, in finding inhibitors of some of the essential cell processes we study, which might be turned into novel antibiotics. The compounds we look for are made by actinomycetes, a fascinating group of bacteria that make many of our current antibiotics and other drugs, and have amazing biology and life cycles.

Finally, we study cell wall deficient or “L-form” bacteria and have described the molecular basis for their growth and proliferation. These curious organisms are interesting for three very fundamental reasons. First, they are good models for primordial cells of interest to thinking about the origins of cellular life. Second, they can be used in innovative ways as “chassis” for synthetic biology applications. Third, they are probably important in a range of chronic, persistent or recurrent infections, such as urinary tract infections.

Work in the Errington lab is funded mainly by two very large grants from the Wellcome Trust and the European Research Council.

Informal enquiries from prospective graduate students and post-docs are welcome at any time.

Key references

Gruber S, Errington J. (2009) Recruitment of the SMC complex to replication origin regions by Spo0J/ParB bound to parS sites in Bacillus subtilis. Cell 137, 685-696.

Mercier R, Kawai Y, Errington J. (2013) Excess membrane synthesis drives a primitive mode of cell proliferation. Cell 152, 997-1007.

Kawai Y, Mickiewicz K, Errington J. (2018) Lysozyme counteracts β-lactam antibiotics by promoting the emergence of L-form bacteria. Cell 172 1038-1104.

Teaching

Undergraduate Teaching

MIC3043, Biomedicine Plus

CME8521, Innovation, IPR & Patents 

CMB3000 project

Postgraduate Teaching

MRes module MMB8016 (Molecular Microbiology)

Ph.D. supervisor

Publications

• Jalal ASB, Tran NT, Wu LJ, Ramakrishnan K, Rejzek M, Gobbato G, Stevenson CEM, Lawson DM, Errington J, Le TBK. CTP regulates membrane-binding activity of the nucleoid occlusion protein Noc. Molecular Cell 2021, 81(17), 3623-3636.e6.
• Emami K, Wu LJ, Errington J. A Small Molecule Inhibitor of CTP Synthetase Identified by Differential Activity on a Bacillus subtilis Mutant Deficient in Class A Penicillin-Binding Proteins. Frontiers in Microbiology 2020, 11, 2001.
• Westblade LF, Errington J, Dorr T. Antibiotic tolerance. PLoS Pathogens 2020, 16(10), e1008892.
• Willis C, Errington J, Wu LJ. Cohesion of sister chromosome termini during the early stages of sporulation in Bacillus subtilis. Journal of Bacteriology 2020, 202(20).
• Wu LJ, Lee S, Park S, Eland LE, Wipat A, Holden S, Errington J. Geometric principles underlying the proliferation of a model cell system. Nature Communications 2020, 11(1), 4149.
• Errington J, van der Aa LT. Microbe profile: Bacillus subtilis: Model organism for cellular development, and industrial workhorse. Microbiology 2020, 166(5), 425-427.
• Egan AJF, Errington J, Vollmer W. Regulation of peptidoglycan synthesis and remodelling. Nature Reviews Microbiology 2020, 18, 446-460.
• Mickiewicz KM, Kawai Y, Drage L, Gomes MC, Davison F, Pickard R, Hall J, Mostowy S, Aldridge PD, Errington J. Author Correction: Possible role of L-form switching in recurrent urinary tract infection (Nature Communications, (2019), 10, 1, (4379), 10.1038/s41467-019-12359-3). Nature Communications 2019, 10, 5254.
• Claessen D, Errington J. Cell Wall Deficiency as a Coping Strategy for Stress. Trends in Microbiology 2019, 27(12), 1025-1033.
• Kawai Y, Mercier R, Mickiewicz K, Serafini A, Sorio de Carvalho LP, Errington J. Crucial role for central carbon metabolism in the bacterial L-form switch and killing by β-lactam antibiotics. Nature Microbiology 2019, 4, 1716-1726.
• Lee S, Wu LJ, Errington J. Microfluidic time-lapse analysis and reevaluation of the Bacillus subtilis cell cycle. MicrobiologyOpen 2019, 8(10), e876.
• Mickiewicz KM, Kawai Y, Drage L, Gomes MC, Davison F, Pickard R, Hall J, Mostowy S, Aldridge PD, Errington J. Possible role of L-form switching in recurrent urinary tract infection. Nature Communications 2019, 10(1), 4379.
• Kawai Y, Mickiewicz K, Errington J. Lysozyme Counteracts β-Lactam Antibiotics by Promoting the Emergence of L-Form Bacteria. Cell 2018, 172(5), 1038-1049.e10.
• Kepplinger B, Morton S, Seistrup K, Marrs E, Hopkins A, Perry J, Strahl H, Hall M, Errington J, Allenby N. Mode of Action and Heterologous Expression of the Natural Product Antibiotic Vancoresmycin. ACS Chemical Biology 2018, 13(1), 207-214.
• Mosaei H, Molodtsov V, Kepplinger B, Harbottle J, Moon C, Jeeves R, Ceccaroni L, Shin Y, Morton-Laing S, Marrs ECL, Wills C, Clegg W, Yuzenkova J, Perry JD, Bacon J, Errington J, Allenby NEE, Hall MJ, Murakami KS, Zenkin N. Mode of Action of Kanglemycin A, an Ansamycin Natural Product that Is Active against Rifampicin Resistant Mycobacterium tuberculosis. Molecular Cell 2018, 72(2), 263-274.
• Holden DW, Errington J. Type II Toxin-Antitoxin Systems and Persister Cells. mBio 2018, 9(5), e01574-18.
• Santos-Beneit F, Gu J-Y, Stimming U, Errington J. ylmD and ylmE genes are dispensable for growth, cross-wall formation and sporulation in Streptomyces venezuelae. Heliyon 2017, 3(11), e00459.
• Santos-Beneit F, Roberts DM, Cantlay S, McCormick JR, Errington J. A mechanism for FtsZ-independent proliferation in Streptomyces. Nature Communications 2017, 8, 1378.
• Strahl H, Errington J. Bacterial Membranes: Structure, Domains, and Function. Annual Review of Microbiology 2017, 71, 519-538.
• Errington J, Wu LJ. Cell cycle machinery in Bacillus subtilis. In: Lowe J; Amos LA, ed. Prokaryotic Cytoskeletons. Springer New York, 2017, pp.67-101.
• Errington J. Cell wall-deficient, L-form bacteria in the 21st century: A personal perspective. Biochemical Society Transactions 2017, 45(2), 287-295.
• Errington J. Designer chemistry. Environmental Microbiology Reports 2017, 9(1), 36-37.
• Sassine J, Xu M, Sidiq KR, Emmins R, Errington J, Daniel RA. Functional redundancy of division specific penicillin-binding proteins in Bacillus subtilis. Molecular Microbiology 2017, 106(2), 304-318.
• Santos-Beneit F, Errington J. Green fluorescent protein as a reporter for the spatial and temporal expression of actIII in Streptomyces coelicolor. Archives of Microbiology 2017, 199(6), 875-880.
• Baksh A, Kepplinger B, Isah H, Probert MR, Clegg W, Wills C, Goodfellow M, Errington J, Allenby N, Hall MJ. Production of 17-O-demethyl-geldanamycin, a cytotoxic ansamycin polyketide, by Streptomyces hygroscopicus DEM20745. Natural Product Research 2017, 31(16), 1895-1900.
• Emami K, Guyet A, Kawai Y, Devi J, Wu LJ, Allenby N, Daniel RA, Errington J. RodA as the missing glycosyltransferase in Bacillus subtilis and antibiotic discovery for the peptidoglycan polymerase pathway. Nature Microbiology 2017, 2, 16253.
• Lewis RA, Li J, Allenby NEE, Errington J, Hayles J, Nurse P. Screening and purification of natural products from actinomycetes that affect the cell shape of fission yeast. Journal of Cell Science 2017, 130(18), 3173-3185.
• Errington J. Spotlight on... Jeff Errington. FEMS Microbiology Letters 2017, 364(11), fnx099.
• Tyler A, Mosaei H, Morton S, Waddell PG, Wills C, McFarlane W, Gray J, Goodfellow M, Errington J, Allenby N, Zenkin N, Hall MJ. Structural Reassignment and Absolute Stereochemistry of Madurastatin C1 (MBJ-0034) and the Related Aziridine Siderophores: Madurastatins A1, B1 and MBJ-0035. Journal of Natural Products 2017, 80(5), 1558–1562.
• Adams DW, Wu LJ, Errington J. A benzamide-dependent ftsZ mutant reveals residues crucial for Z-ring assembly. Molecular Microbiology 2016, 99(6), 1028-1042.
• Kloosterman TG, Lenarcic R, Willis CR, Roberts DM, Hamoen LW, Errington J, Wu LJ. Complex polar machinery required for proper chromosome segregation in vegetative and sporulating cells of Bacillus subtilis. Molecular Microbiology 2016, 101(2), 333-350.
• Errington J, Mickiewicz K, Kawai Y, Wu LJ. L-form bacteria, chronic diseases and the origins of life. Philosophical Transactions of the Royal Society B: Biological Sciences 2016, 371(1707).
• Mercier R, Kawai Y, Errington J. Wall proficient E-coli capable of sustained growth in the absence of the Z-ring division machine. Nature Microbiology 2016, 1(8), 16091.
• Errington J. Bacterial morphogenesis and the enigmatic MreB helix. Nature Reviews Microbiology 2015, 13(4), 241-248.
• Kawai Y, Mercier R, Wu LJ, Dominguez-Cuevas P, Oshima T, Errington J. Cell Growth of Wall-Free L-Form Bacteria Is Limited by Oxidative Damage. Current Biology 2015, 25(12), 1613-1618.
• Adams DW, Wu LJ, Errington J. Nucleoid occlusion protein Noc recruits DNA to the bacterial cell membrane. EMBO Journal 2015, 34(4), 491-501.
• Kawai Y, Mercier R, Errington J. Bacterial Cell Morphogenesis Does Not Require a Preexisting Template Structure. Current Biology 2014, 24(8), 863-867.
• Adams DW, Wu LJ, Errington J. Cell cycle regulation by the bacterial nucleoid. Current Opinion in Microbiology 2014, 22, 94-101.
• Mercier R, Kawai Y, Errington J. General principles for the formation and proliferation of a wall-free (L-form) state in bacteria. eLife 2014, 3, e04629.
• Gruber S, Veening JW, Bach J, Blettinger M, Bramkamp M, Errington J. Interlinked Sister Chromosomes Arise in the Absence of Condensin during Fast Replication in B. subtilis. Current Biology 2014, 24(3), 293-298.
• Trip EN, Veening JW, Stewart EJ, Errington J, Scheffers DJ. Balanced transcription of cell division genes in Bacillus subtilis as revealed by single cell analysis. Environmental Microbiology 2013, 15(12), 3196-3209.
• Domínguez-Cuevas P, Porcelli I, Daniel RA, Errington J. Differentiated roles for MreB-actin isologues and autolytic enzymes in Bacillus subtilis morphogenesis. Molecular Microbiology 2013, 89(6), 1084-1098.
• Mercier R, Kawai Y, Errington J. Excess Membrane Synthesis Drives a Primitive Mode of Cell Proliferation. Cell 2013, 152(5), 997-1007.
• Errington J. L-form bacteria, cell walls and the origins of life. Open Biology 2013, 3, 120143.
• Surdova K, Gamba P, Claessen D, Siersma T, Jonker MJ, Errington J, Hamoen LW. The Conserved DNA-Binding Protein WhiA Is Involved in Cell Division in Bacillus subtilis. Journal of Bacteriology 2013, 195(24), 5450-5460.
• Mercier R, Dominguez-Cuevas P, Errington J. Crucial Role for Membrane Fluidity in Proliferation of Primitive Cells. Cell Reports 2012, 1(5), 417-423.
• Wu LJ, Errington J. Nucleoid occlusion and bacterial cell division. Nature Reviews Microbiology 2012, 10(1), 8-12.
• Scholefield G, Errington J, Murray H. Soj/ParA stalls DNA replication by inhibiting helix formation of the initiator protein DnaA. EMBO Journal 2012, 31(6), 1542-1555.
• Dominguez-Cuevas P, Mercier R, Leaver M, Kawai Y, Errington J. The rod to L-form transition of Bacillus subtilis is limited by a requirement for the protoplast to escape from the cell wall sacculus. Molecular Microbiology 2012, 83(1), 52-66.
• Kawai Y, Marles-Wright J, Cleverley RM, Emmins R, Ishikawa S, Kuwano M, Heinz N, Bui NK, Hoyland CN, Ogasawara N, Lewis RJ, Vollmer W, Daniel RA, Errington J. A widespread family of bacterial cell wall assembly proteins. EMBO Journal 2011, 30(24), 4931-4941.
• Gündoğdu ME, Kawai Y, Pavlendova N, Ogasawara N, Errington J, Scheffers DJ, Hamoen LW. Large ring polymers align FtsZ polymers for normal septum formation. EMBO Journal 2011, 30(3), 617-626.
• Adams DW, Wu LJ, Czaplewski LG, Errington J. Multiple effects of benzamide antibiotics on FtsZ function. Molecular Microbiology 2011, 80(1), 68-84.
• Scholefield G, Whiting R, Errington J, Murray H. Spo0J regulates the oligomeric state of Soj to trigger its switch from an activator to an inhibitor of DNA replication initiation. Molecular Microbiology 2011, 79(4), 1089-1100.
• Su'etsugu M, Errington J. The Replicase Sliding Clamp Dynamically Accumulates behind Progressing Replication Forks in Bacillus subtilis Cells. Molecular Cell 2011, 41(6), 720-732.
• Errington J. From spores to antibiotics via the cell cycle. Microbiology 2010, 156(1), 1-13.
• Deghorain M, Fontaine L, David B, Mainardi JL, Courtin P, Daniel R, Errington J, Sorokin A, Bolotin A, Chapot-Chartier MP, Hallet B, Hols P. Functional and Morphological Adaptation to Peptidoglycan Precursor Alteration in Lactococcus lactis. Journal of Biological Chemistry 2010, 285(31), 24003-24013.
• Nijland R, Burgess JG, Errington J, Veening JW. Transformation of Environmental Bacillus subtilis Isolates by Transiently Inducing Genetic Competence. PLoS One 2010, 5(3), e9724.
• Engl C, Jovanovic G, Lloyd LJ, Murray H, Spitaler M, Ying LM, Errington J, Buck M. In vivo localizations of membrane stress controllers Escherichia coli. Molecular Microbiology 2009, 73(3), 382-396.
• Veening JW, Murray H, Errington J. A mechanism for cell cycle regulation of sporulation initiation in Bacillus subtilis. Genes & Development 2009, 23(16), 1959-1970.
• Adams DW, Errington J. Bacterial cell division: assembly, maintenance and disassembly of the Z ring. Nature Reviews Microbiology 2009, 7(9), 642-653.
• Eberhardt A, Wu LJ, Errington J, Vollmer W, Veening J-W. Cellular localization of choline-utilization proteins in Streptococcus pneumoniae using novel fluorescent reporter systems. Molecular Microbiology 2009, 74(2), 395-408.
• Schirner K, Marles-Wright J, Lewis RJ, Errington J. Distinct and essential morphogenic functions for wall- and lipo-teichoic acids in Bacillus subtilis. EMBO Journal 2009, 28(7), 830-842.
• Moriya S, Kawai Y, Kaji S, Smith A, Harry EJ, Errington J. Effects of oriC relocation on control of replication initiation in Bacillus subtilis. Microbiology 2009, 155, 3070-3082.
• Schirner K, Errington J. Influence of heterologous MreB proteins on cell morphology of Bacillus subtilis. Microbiology 2009, 155, 3611-3621.
• Leaver M, Dominguez-Cuevas P, Coxhead JM, Daniel RA, Errington J. Life without a wall or division machine in Bacillus subtilis. Nature 2009, 457(7231), 849-853.
• Lenarcic R, Halbedel S, Visser L, Shaw M, Wu LJ, Errington J, Marenduzzo D, Hamoen LW. Localisation of DivIVA by targeting to negatively curved membranes. EMBO Journal 2009, 28(15), 2272-2282.
• Wu LJ, Ishikawa S, Kawai Y, Oshima T, Ogasawara N, Errington J. Noc protein binds to specific DNA sequences to coordinate cell division with chromosome segregation. EMBO Journal 2009, 28(13), 1940-1952.
• Kawai Y, Asai K, Errington J. Partial functional redundancy of MreB isoforms, MreB, Mbl and MreBH, in cell morphogenesis of Bacillus subtilis. Molecular Microbiology 2009, 73(4), 719-731.
• Gruber S, Errington J. Recruitment of Condensin to Replication Origin Regions by ParB/SpoOJ Promotes Chromosome Segregation in B. subtilis. Cell 2009, 137(4), 685-696.
• Kawai Y, Daniel RA, Errington J. Regulation of cell wall morphogenesis in Bacillus subtilis by recruitment of PBP1 to the MreB helix. Molecular Microbiology 2009, 71(5), 1131-1144.
• Muñoz-Espín D, Daniel R, Kawai Y, Carballido-López R, Castilla-Llorente V, Errington J, Meijer WJJ, Salas M. The actin-like MreB cytoskeleton organizes viral DNA replication in bacteria. Proceedings of the National Academy of Sciences 2009, 106(32), 13347-13352.
• Schirner K, Errington J. The Cell Wall Regulator σ^I Specifically Suppresses the Lethal Phenotype of mbl Mutants in Bacillus subtilis. Journal of Bacteriology 2009, 191(5), 1404-1413.
• Bramkamp M, Emmins R, Weston L, Donovan C, Daniel RA, Errington J. A novel component of the division site selection system of Bacillus subtilis and a new mode of action for the division inhibitor MinCD. Molecular Microbiology 2008, 70(6), 1556-1569.
• Haydon D, Stokes N, Ure R, Galbraith G, Bennett J, Brown D, Baker P, Barynin V, Rice D, Sedelnikova S, Heal J, Sheridan J, Aiwale S, Chauhan P, Srivastava A, Taneja A, Collins I, Errington J, Czaplewski L. An inhibitor of FtsZ with potent and selective anti-staphylococcal activity. Science 2008, 321(5896), 1673-1675.
• Wu LJ, Errington J. Cell biology: DNA versus membrane. Nature 2008, 451(7181), 900-901.
• Claessen D, Emmins R, Hamoen LW, Daniel RA, Errington J, Edwards DH. Control of the cell elongation-division cycle by shuttling of PBP1 protein in Bacillus subtilis. Molecular Microbiology 2008, 68(4), 1029-1046.
• Murray HD, Errington J. Dynamic Control of the DNA Replication Initiation Protein DnaA by Soj/ParA. Cell 2008, 135(1), 74-84.
• Formstone A, Carballido-Lopez R, Noirot P, Errington J, Scheffers D-J. Localization and interactions of teichoic acid synthetic enzymes in Bacillus subtilis. Journal of Bacteriology 2008, 190(5), 1812-1821.
• Lecointe F, Serena C, Velten M, Costes A, McGovern S, Meile J-C, Errington J, Ehrlich SD, Noirot P, Polard P. Anticipating chromosomal replication fork arrest: SSB targets repair DNA helicases to active forks. EMBO Journal 2007, 26(19), 4239-4251.
• Xu L, Sedelnikova SE, Baker PJ, Hunt A, Errington J, Rice DW. Crystal structure of S. aureus YlaN, an essential leucine rich protein involved in the control of cell shape. Proteins: Structure, Function and Genetics 2007, 68(2), 438-445.
• Thomaides HB, Davison EJ, Burston L, Johnson H, Brown DR, Hunt AC, Errington J, Czaplewski L. Essential bacterial functions encoded by gene pairs. Journal of Bacteriology 2007, 189(2), 591-602.
• Deghorain M, Goffin P, Fontaine L, Mainardi J-L, Daniel R, Errington J, Hallet B, Hols P. Selectivity for D-lactate incorporation into the peptidoglycan precursors of Lactobacillus plantarum: Role of Aad, a VanX-like D-alanyl-D-alanine dipeptidase. Journal of Bacteriology 2007, 189(11), 4332-4337.
• Gilbert Y, Deghorain M, Wang L, Xu B, Pollheimer PD, Gruber HJ, Errington J, Hallet B, Haulot X, Verbelen C, Hols P, Dufrene YF. Single-molecule force spectroscopy and imaging of the vancomycin/D-Ala-D- Ala interaction. Nano Letters 2007, 7(3), 796-801.
• Carballido-Lopez R, Formstone A, Li Y, Ehrlich SD, Noirot P, Errington J. Actin Homolog MreBH Governs Cell Morphogenesis by Localization of the Cell Wall Hydrolase LytE. Developmental Cell 2006, 11(3), 399-409.
• Van Den Ent F, Leaver M, Bendezu F, Errington J, De Boer P, Lowe J. Dimeric structure of the cell shape protein MreC and its functional implications. Molecular Microbiology 2006, 62(6), 1631-1642.
• Errington J. Fluorescence microscopy as a research tool in bacterial cell biology. Microbiology Today 2006, 33(3), 96-98.
• Hunt A, Rawlins JP, Thomaides HB, Errington J. Functional analysis of 11 putative essential genes in Bacillus subtilis. Microbiology 2006, 152(10), 2895-2907.
• Daniel RA, Noirot-Gros M-F, Noirot P, Errington J. Multiple interactions between the transmembrane division proteins of Bacillus subtilis and the role of FtsL instability in divisome assembly. Journal of Bacteriology 2006, 188(21), 7396-7404.
• Bramkamp M, Weston L, Daniel RA, Errington J. Regulated intramembrane proteolysis of FtsL protein and the control of cell division in Bacillus subtilis. Molecular Microbiology 2006, 62(2), 580-591.
• Hamoen LW, Meile JC, de Jong W, Noirot P, Errington J. SepF, a novel FtsZ-interacting protein required for a late step in cell division. Molecular Microbiology 2006, 59(3), 989-999.
• Meile J-C, Wu LJ, Ehrlich SD, Errington J, Noirot P. Systematic localisation of proteins fused to the green fluorescent protein in Bacillus subtilis: identification of new proteins at the DNA replication factory. Proteomics 2006, 6(7), 2135-2146.
• Murray H, Ferreira H, Errington J. The bacterial chromosome segregation protein Spo0J spreads along DNA from parS nucleation sites. Molecular Microbiology 2006, 61(5), 1352-1361.
• Sidebottom E, Smith A, Stokes N, Errington J. Wartime penicillin still packing a punch. Microbiology Today 2006, 33(2), 62-63.
• Feucht A, Errington J. ftsZ mutations affecting cell division frequency, placement and morphology in Bacillus subtilis. Microbiology 2005, 151(6), 2053-2064.
• Formstone A, Errington J. A magnesium-dependent mreB null mutant: implications for the role of mreB in Bacillus subtilis. Molecular Microbiology 2005, 55(6), 1646-1657.
• Real G, Autret S, Harry EJ, Errington J, Henriques AO. Cell division protein DivIB influences the Spo0J/Soj system of chromosome segregation in Bacillus subtilis. Molecular Microbiology 2005, 55(2), 349-367.
• Errington J, Murray H, Wu LJ. Diversity and redundancy in bacterial chromosome segregation mechanisms. Philosophical Transactions of the Royal Society B: Biological Sciences 2005, 360(1455), 497-505.
• Meijer WJ, Castilla-Llorente V, Villar L, Murray H, Errington J, Salas M. Molecular basis for the exploitation of spore formation as survival mechanism by virulent phage φ29. EMBO Journal 2005, 24(20), 3647-3657.
• Stokes NR, Sievers J, Barker S, Bennett JM, Brown DR, Collins I, Errington VM, Foulger D, Hall M, Halsey R, Johnson H, Rose V, Thomaides HB, Haydon DJ, Czaplewski LG, Errington J. Novel inhibitors of bacterial cytokinesis identified by a cell-based antibiotic screening assay. Journal of Biological Chemistry 2005, 280(48), 39709-39715.
• Pinho MG, Errington J. Recruitment of penicillin-binding protein PBP2 to the division site of Staphylococcus aureus is dependent on its transpeptidation substrates. Molecular Microbiology 2005, 55(3), 799-807.
• Leaver M, Errington J. Roles for MreC and MreD proteins in helical growth of the cylindrical cell wall in Bacillus subtilis. Molecular Microbiology 2005, 57(5), 1196-1209.
• Pinho MG, Errington J. A divIVA null mutant of Staphylococcus aureus undergoes normal cell division. FEMS Microbiology Letters 2004, 240(2), 145-149.
• Wu LJ, Errington J. Coordination of Cell Division and Chromosome Segregation by a Nucleoid Occlusion Protein in Bacillus subtilis. Cell 2004, 117(7), 915-925.
• Evans L, Feucht A, Errington J. Genetic analysis of the Bacillus subtilis sigG promoter, which controls the sporulation-specific transcription factor σG. Microbiology 2004, 150(7), 2277.
• Errington J. Making money from microbes - case studies: spinning out. Microbiology Today 2004, 31(1), 10.
• Scheffers DJ, Errington J. PBP1 is a component of the Bacillus subtilis cell division machinery. Journal of Bacteriology 2004, 186(15), 5153-5156.
• Scheffers D-J, Jones LJF, Errington J. Several distinct localisation patterns for penicillin-binding proteins in Bacillus subtilis. Molecular Microbiology 2004, 51(3), 749-764.
• Carballido-Lopez R, Errington J. A dynamic bacterial cytoskeleton. Trends in Cell Biology 2003, 13(11), 577-583.
• Autret S, Errington J. A role for division-site-selection protein MinD in regulation of internucleoid jumping of Soj (ParA) protein in Bacillus subtilis. Molecular Microbiology 2003, 47(1), 159-169.
• Evans L, Clarkson J, Yudkin MD, Errington J, Feucht A. Analysis of the interaction between the transcription factor σ^G and the anti-sigma factor SpoIIAB of Bacillus subtilis. Journal of Bacteriology 2003, 185(15), 4615-4619.
• Daniel RA, Errington J. Control of Cell Morphogenesis in Bacteria: Two Distinct Ways to Make a Rod-Shaped Cell. Cell 2003, 113(6), 767-776.
• Errington J, Daniel RA, Scheffers DJ. Cytokinesis in bacteria. Microbiology and Molecular Biology Reviews 2003, 67(1), 52-65.
• Pinho MG, Errington J. Dispersed mode of Staphylococcus aureus cell wall synthesis in the absence of the division machinery. Molecular Microbiology 2003, 50(3), 871-881.
• Errington J. Dynamic proteins and a cytoskeleton in bacteria. Nature Cell Biology 2003, 5(3), 175-178.
• Kobayashi K, Ehrlich SD, Albertini A, Amati G, Andersen KK, Arnaud M, Asai K, Ashikaga S, Aymerich S, Bessieres P, Boland F, Brignell SC, Bron S, Bunai K, Chapuis J, Christiansen LC, Danchin A, Debarbouille M, Dervyn E, Deuerling E, Devine K, Devine SK, Dreesen O, Errington J, Fillinger S, Foster SJ, Fujita Y, Galizzi A, Gardan R, Eschevins C, Fukushima T, Haga K, Harwood CR, Hecker M, Hosoya D, Hullo MF, Kakeshita H, Karamata D, Kasahara Y, Kawamura F, Koga K, Koski P, Kuwana R, Imamura D, Ishimaru M, Ishikawa S, Ishio I, Le Coq D, Masson A, Mauel C, Meima R, Mellado RP, Moir A, Moriya S, Nagakawa E, Nanamiya H, Nakai S, Nygaard P, Ogura M, Ohanan T, O'Reilly M, O'Rourke M, Pragai Z, Pooley HM, Rapoport G, Rawlins JP, Rivas LA, Rivolta C, Sadaie A, Sadaie Y, Sarvas M, Sato T, Saxild HH, Scanlan E, Schumann W, Seegers JFML, Sekiguchi J, Sekowska A, Seror SJ, Simon M, Stragier P, Studer R, Takamatsu H, Tanaka T, Takeuchi M, Thomaides HB, Vagner V, Van Dijl JM, Watabe K, Wipat A, Yamamoto H, Yamamoto M, Yamamoto Y, Yamane K, Yata K, Yoshida K, Yoshikawa H, Zuber U, Ogasawara N. Essential Bacillus subtilis genes. Proceedings of the National Academy of Sciences 2003, 100(8), 4678-4683.
• Feucht A, Evans L, Errington J. Identification of sporulation genes by genome-wide analysis of the sE regulon of Bacillus subtilis. Microbiology 2003, 149(10), 3023-3034.
• Hamoen LW, Errington J. Polar targeting of DivIVA in Bacillus subtilis is not directly dependent on FtsZ or PBP 2B. Journal of Bacteriology 2003, 185(2), 693-697.
• Wu LJ, Errington J. RacA and the Soj-Spo0J system combine to effect polar chromosome segregation in sporulating Bacillus subtilis. Molecular Microbiology 2003, 49(6), 1463-1475.
• Errington J. Regulation of endospore formation in Bacillus subtilis. Nature Reviews Microbiology 2003, 1(2), 117-126.
• Errington J. The bacterial actin cytoskeleton. ASM News 2003, 69, 608-614.
• Carballido-López R, Errington J. The bacterial cytoskeleton: in vivo dynamics of the actin-like protein Mbl of Bacillus subtilis. Developmental Cell 2003, 4(1), 19-28.
• Wu LJ, Errington J. A large dispersed chromosomal region required for chromosome segregation in sporulating cells of Bacillus subtilis. EMBO Journal 2002, 21(15), 4001-4011.
• Noirot-Gros MF, Dervyn E, Wu LJ, Mervelet P, Errington J, Ehrlich SD, Noirot P. An expanded view of bacterial DNA replication. Proceedings of the National Academy of Sciences of the United States of America 2002, 99(12), 8342-8347.
• Errington J, Daniel RA. Cell division during growth and sporulation. In: Sonenshein, L; Losick, R; Hoch, JA, ed. Bacillus Subtilis and Its Closest Relatives: From Genes to Cells. Washington, D.C: American Society for Microbiology, 2002, pp.97-109.
• Sievers J, Raether B, Perego M, Errington J. Characterization of the parB-like yyaA gene of Bacillus subtilis. Journal of Bacteriology 2002, 184(4), 1102-1111.
• Feucht A, Abbotts L, Errington J. The cell differentiation protein SpoIIE contains a regulatory site that controls its phosphatase activity in response to asymmetric septation. Molecular Microbiology 2002, 45(4), 1119-1130.
• Errington J, Bath J, Wu LJ. Bacterial DNA transport. Nature Reviews Molecular Cellular Biology 2001, 2(7), 538-545.
• Jones LJF, Carballido-López R, Errington J. Control of Cell Shape in Bacteria: Helical, Actin-like Filaments in Bacillus subtilis. Cell 2001, 104(6), 913-922.
• Feucht A, Lucet I, Yudkin MD, Errington J. Cytological and biochemical characterization of the FtsA cell division protein of Bacillus subtilis. Molecular Microbiology 2001, 40(1), 115-125.
• Thomaides HB, Freeman M, Karoui MEl, Errington J. Division site selection protein DivIVA of Bacillus subtilis has a second distinct function in chromosome segregation during sporulation. Genes & Development 2001, 15(13), 1662-1673.
• Autret S, Errington J. Dynamic proteins in bacteria. Developmental Cell 2001, 1(1), 10-11.
• Thomas JD, Daniel RA, Errington J, Robinson C. Export of active green fluorescent protein to the periplasm by the twin-arginine translocase (Tat) pathway in Escherichia coli. Molecular Microbiology 2001, 39(1), 47-53.
• Autret S, Nair R, Errington J. Genetic analysis of the chromosome segregation protein Spo0J of Bacillus subtilis: evidence for separate domains involved in DNA binding and interactions with Soj protein. Molecular Microbiology 2001, 41(3), 743-755.
• Karoui MEl, Errington J. Isolation and characterization of topological specificity mutants of minD in Bacillus subtilis. Molecular Microbiology 2001, 42(5), 1211-1221.
• Errington J. Septation and chromosome segregation during sporulation in Bacillus subtilis. Current Opinion in Microbiology 2001, 4(6), 660-666.
• Dervyn E, Suski C, Daniel RA, Bruand C, Chapuis J, Errington J, Jannière L, Ehrlich SD. Two Essential DNA Polymerases at the Bacterial Replication Fork. Science 2001, 294(5547), 1716-1719.
• Sievers J, Errington J. Analysis of the essential cell division gene ftsL of Bacillus subtilis by mutagenesis and heterologous complementation. Journal of Bacteriology 2000, 182(19), 5572-5579.
• Lewis PJ, Thaker SD, Errington J. Compartmentalization of transcription and translation in Bacillus subtilis. EMBO Journal 2000, 19(4), 710-718.
• Lucet I, Feucht A, Yudkin MD, Errington J. Direct interaction between the cell division protein FtsZ and the cell differentiation protein SpoIIE. EMBO Journal 2000, 19(7), 1467-1475.
• Meijer WJJ, Lewis PJ, Errington J, Salas M. Dynamic relocalization of phage φ29 DNA during replication and the role of the viral protein p16.7. EMBO Journal 2000, 19(15), 4182-4190.
• Wu LJ, Errington J. Identification and characterization of a new prespore-specific regulatory gene, rsfA, of Bacillus subtilis. Journal of Bacteriology 2000, 182(2), 418-424.
• Daniel RA, Errington J. Intrinsic instability of the essential cell division protein FtsL of Bacillus subtilis and a role for DivIB protein in FtsL turnover. Molecular Microbiology 2000, 36(2), 278-289.
• Edwards DH, Thomaides HB, Errington J. Promiscuous targeting of Bacillus subtilis cell division protein DivIVA to division sites in Escherichia coli and fission yeast. EMBO Journal 2000, 19(11), 2719-2727.
• Bath J, Wu LJ, Errington J, Wang JC. Role of Bacillus subtilis SpoIIIE in DNA transport across the mother cell-prespore division septum. Science 2000, 290(5493), 995-997.
• Daniel RA, Harry EJ, Errington J. Role of penicillin-binding protein PBP 2B in assembly and functioning of the division machinery of Bacillus subtilis. Molecular Microbiology 2000, 35(2), 299-311.
• Sievers J, Errington J. The Bacillus subtilis cell division protein FtsL localizes to sites of septation and interacts with DivIC. Molecular Microbiology 2000, 36(4), 846-855.
• Feucht A, Daniel RA, Errington J. Characterization of a morphological checkpoint coupling cell-specific transcription to septation in Bacillus subtilis. Molecular Microbiology 1999, 33(5), 1015-1026.
• Marston AL, Errington J. Dynamic movement of the ParA-like Soj protein of B. subtilis and its dual role in nucleoid organization and developmental regulation. Molecular Cell 1999, 4(5), 673-682.
• Feucht A, Errington J. Negative regulation of sA activity during sporulation in Bacillus subtilis. Molecular Microbiology 1999.
• Sharpe ME, Errington J. Role of spo0 genes in regulation of axial filament formation during sporulation in Bacillus subtilis. Molecular Microbiology 1999.
• Marston AL, Errington J. Selection of the midcell division site in Bacillus subtilis through MinD-dependent polar localization and activation of MinC. Molecular Microbiology 1999, 33(1), 84-96.
• Sharpe ME, Errington J. Upheaval in the bacterial nucleoid: an active chromosome segregation mechanism. Trends in Genetics 1999, 15(2), 70-74.
• Sharpe ME, Hauser PM, Sharpe RG, Errington J. Bacillus subtilis cell cycle as studied by fluorescence microscopy: constancy of the cell length at initiation of DNA replication and evidence for active nucleoid partitioning. Journal of Bacteriology 1998, 180(3), 547-555.
• Foulger D, Errington J. A 28 kbp segment from the spoVM region of the Bacillus subtilis 168 genome. Microbiology 1998, 144(3), 801-805.
• Sharpe ME, Errington J. A fixed distance for separation of newly replicated copies of oriC in Bacillus subtilis: implications for co-ordination of chromosome segregation and cell division. Molecular Microbiology 1998, 28(5), 981-990.
• Daniel RA, Harry EJ, Katis VL, Wake RG, Errington J. Characterization of the essential cell division gene ftsL (yllD) of Bacillus subtilis and its role in the assembly of the division apparatus. Molecular Microbiology 1998, 29(2), 593-604.
• Errington J. Dramatic new view of bacterial chromosome segregation. ASM News 1998, 64(4), 210-217.
• Lewis PJ, Wu LJ, Errington J. Establisment of prespore-specific gene expression in Bacillus subtilis: localisation of SpoIIE phosphatase and initiation of compartment-specific proteolysis. Journal of Bacteriology 1998, 180(13), 3276-3284.
• Marston AL, Thomaides HB, Edwards DH, Sharpe ME, Errington J. Polar localization of the MinD protein of Bacillus subtilis and its role in selection of the mid-cell division site. Genes and Development 1998, 12(21), 3419-3430.
• Wu LJ, Feucht A, Errington J. Prespore-specific gene expression in Bacillus subtilis is driven by sequestration of SpoIIE phosphatase to the prespore side of the asymmetric septum. Genes and Development 1998, 12(9), 1371-1380.
• Errington J, Daniel RA, Feucht A, Lewis PJ, Wu LJ. Regulation of prespore-specific transcription during sporulation in Bacillus subtilis. In: Molecular Microbiology. 1998, Birmingham, UK: Berlin Heidelberg: Springer-Verlag.
• Wu LJ, Errington J. Use of asymmetric cell division and spoIIIE mutants to probe chromosome orientation and organization in Bacillus subtilis. Molecular Microbiology 1998, 27(4), 777-786.
• Zhang B, Daniel RA, Errington J, Kroos L. Bacillus subtilis SpoIIID protein binds to two sites in the spoVD promoter and represses transcription by sE RNA polymerase. Journal of Bacteriology 1997, 179(3), 972-975.
• Lewis PJ, Errington J. Direct evidence for active segregation of oriC regions of the Bacillus subtilis chromosome and co-localization with the Spo0J partitioning protein. Molecular Microbiology 1997, 25(5), 945-954.
• Glaser P, Sharpe ME, Raether B, Perego M, Ohlsen K, Errington J. Dynamic, mitotic-like behaviour of a bacterial protein required for accurate chromosome partitioning. Genes and Development 1997, 11(9), 1160-1168.
• Daniel RA, Haiech J, Denizot F, Errington J. Isolation and characterization of the lacA gene encoding b-galactosidase in Bacillus subtilis and a regulator gene, lacR. Journal of Bacteriology 1997, 179(17), 5636-5638.
• Wu LJ, Errington J. Septal localization of the SpoIIIE chromosome partitioning protein in Bacillus subtilis. EMBO Journal 1997, 16(8), 2161-2169.
• Edwards DH, Errington J. The Bacillus subtilis DivIVA protein targets to the division septum and controls the site specificity of cell division. Molecular Microbiology 1997, 24(5), 905-915.
• Kunst F, Ogasawara N, Moszer I, Albertini AM, Alloni G, Azevedo V, Bertero MG, Bessieres P, Bolotin A, Borchert S, Borriss R, Boursier L, Brans A, Braun M, Brignell SC, Bron S, Brouillet S, Bruschi CV, Caldwell B, Capuano V, Carter NM, Choi S-K, Codani J-J, Connerton IF, Cummings NJ, Daniel RA, Denizot F, Devine KM, Dusterhoft A, Ehrlich SD, Emmerson PT, Entian KD, Errington J, Fabret C, Ferrari E, Foulger D, Fritz C, Fujita M, Fujita Y, Fuma S, Galizzi A, Galleron N, Ghim S-Y, Glaser P, Goffeau A, Golightly EJ, Grandi G, Guiseppi G, Guy BJ, Haga K, Haiech J, Harwood CR, Henaut A, Hilbert H, Holsappel S, Hosono S, Hullo M-F, Itaya M, Jones L, Joris B, Karamata D, Kasahara Y, Klaerr-Blanchard M, Klein C, Kobayashi Y, Koetter P, Koningstein G, Krogh S, Kumano M, Kurita K, Lapidus A, Lardinois S, Lauber J, Lazarevic V, Lee S-M, Levine A, Liu H, Masuda S, Mauel C, Medigue C, Medina N, Mellado RP, Mizuno M, Moestl D, Nakai S, Noback M, Noone D, O'Reilly M, Ogawa K, Ogiwara A, Oudega B, Park S-H, Parro V, Pohl TM, Portetelle D, Porwollik S, Prescott AM, Presecan E, Pujic P. The complete genome sequence of the gram-positive bacterium Bacillus subtilis. Nature 1997, 390(6657), 249-256.
• Daniel RA, Williams AM, Errington J. A complex four-gene operon containing essential cell division gene pbpB in Bacillus subtilis. Journal of Bacteriology 1996, 178(8), 2343-2350.
• Feucht A, Magnin T, Yudkin MD, Errington J. Bifunctional protein required for asymmetric cell division and cell-specific transcription in Bacillus subtilis. Genes and Development 1996, 10(7), 794-803.
• Lewis PJ, Magnin T, Errington J. Compartmentalized distribution of the proteins controlling the prespore-specific transcription factor σ^F of Bacillus subtilis. Genes to Cells 1996, 1(10), 881-894.
• Errington J, Feucht A, Lewis PJ, Lord M, Magnin T, Najafi SMA, Wilkinson JF, Yudkin MD. Control of the cell-specificity of sF activity in Bacillus subtilis. Philosophical Transactions of the Royal Society B: Biological Sciences 1996, 351(1339), 537-542.
• Errington J. Determination of cell fate in Bacillus subtilis. Trends in Genetics 1996, 12(1), 31-34.
• Magnin T, Lord M, Errington J, Yudkin MD. Establishing differential gene expression in sporulating Bacillus subtilis: phosphorylation of SpoIIAA (anti-anti-σ^F) alters its conformation and prevents formation of a SpoIIAA/SpoIIAB/ADP complex. Molecular Microbiology 1996, 19(4), 901-907.
• Vicente M, Errington J. Structure, function and controls in microbial division. Molecular Microbiology 1996, 20(1), 1-7.
• Sharpe ME, Errington J. The Bacillus subtilis soj-spo0J locus is required for a centromere-like function involved in prespore chromosome partitioning. Molecular Microbiology 1996, 21(3), 501-509.
• Parker GF, Daniel RA, Errington J. Timing and genetic regulation of commitment to sporulation in Bacillus subtilis. Microbiology 1996, 142(12), 3445-3452.
• Lewis PJ, Errington J. Use of green fluorescent protein for detection of cell-specific gene expression and subcellular protein localization during sporulation in Bacillus subtilis. Microbiology 1996, 142(4), 733-740.
• Wu LJ, Lewis PJ, Allmansberger R, Hauser PM, Errington J. A conjugation-like mechanism for prespore chromosome partitioning during sporulation in Bacillus subtilis. Genes and Development 1995, 9(11), 1316-1326.
• Hauser PM, Errington J. Characterization of cell cycle events during the onset of sporulation in Bacillus subtilis. Journal of Bacteriology 1995, 177(14), 3923-3931.
• Wake RG, Errington J. Chromosome partitioning in bacteria. Annual Review of Genetics 1995, 29(1), 41-67.
• Foulger D, Parker GF, Errington J. Medium-dependent sporulation resulting from a mutation in the spoIIAB gene of Bacillus subtilis. Microbiology 1995, 141(7), 1763-1769.
• Sharpe ME, Errington J. Postseptational chromosome partitioning in bacteria. Proceedings of the National Academy of Sciences of the United States of America 1995, 92(19), 8630-8634.
• Rowland SL, Errington J, Wake RG. The Bacillus subtilis cell-division 135-137^o region contains an essential orf with significant similarity to murB and a dispensible sbp gene. Gene 1995, 164(1), 113-116.
• Wu LJ, Errington J. Bacillus subtilis SpoIIIE protein required for DNA segregation during asymmetric cell division. Science 1994, 264(5158), 572-575.
• Leung Y-C, Errington J. Characterization of an insertion in the phage φ105 genome that blocks host Bacillus subtilis lysis and provides strong expression of heterologous genes. Gene 1994, 154(1), 1-6.
• Diederich B, Wilkinson JF, Magnin T, Najafi SMA, Errington J, Yudkin MD. Role of interactions between SpoIIAA and SpoIIAB in regulating cell-specific transcription factor sigma F of Bacillus subtilis. Genes and Development 1994, 8(21), 2653-2663.
• Lewis PJ, Partridge SR, Errington J. Sigma factors, asymmetry, and the determination of cell fate in Bacillus subtilis. Proceedings of the National Academy of Sciences of the United States of America 1994, 91(9), 3849-3853.
• Daniel RA, Drake S, Buchanan CE, Scholle R, Errington J. The Bacillus subtilis spoVD gene encodes a mother-cell-specific penicillin-binding protein required for spore morphogenesis. Journal of Molecular Biology 1994, 235(1), 209-220.
• Lewis PJ, Nwoguh CE, Barer MR, Harwood CR, Errington J. Use of digitized video microscopy with a fluorogenic enzyme substrate to demonstrate cell- and compartment-specific gene expression in Salmonella enteritidis and Bacillus subtilis. Molecular Microbiology 1994, 13, 655-662.
• Errington J. Bacillus subtilis sporulation: regulation of gene expression and control of morphogenesis. Microbiological Reviews 1993, 57(1), 1-33.
• Min K-T, Hilditch CM, Diederich B, Errington J, Yudkin MD. σ^F, the first compartment-specific transcription factor of B. subtilis, is regulated by an anti-σ factor that is also a protein kinase. Cell 1993, 74(4), 735-742.
• Thornewell SJ, East AK, Errington J. An efficient expression and secretion system based on Bacillus subtilis phage φ105 and its use for the production of B. cereus β-lactamase I. Gene 1993, 133(1), 47-53.
• Yanouri A, Daniel RA, Errington J, Buchanan CE. Cloning and sequencing of the cell division gene pbpB, which encodes penicillin-binding protein 2B in Bacillus subtilis. Journal of Bacteriology 1993, 175(23), 7604-7616.
• Daniel RA, Errington J. Cloning, DNA sequence, functional analysis and transcriptional regulation of the genes encoding dipicolinic acid synthesis required for sporulation in Bacillus subtilis. Journal of Molecular Biology 1993, 232(2), 468-483.
• Daniel RA, Errington J. DNA sequence of the murE-murD region of Bacillus subtilis 168. Journal of General Microbiology 1993, 139(2), 361-370.
• Foulger D, Errington J. Effects of new mutations in the spoIIAB gene of Bacillus subtilis on the regulation of σ^F and σ^G activities. Journal of General Microbiology 1993, 139(12), 3197-3203.
• Errington J. Temperate phage vectors. In: Sonenshein, AL; Hoch, JA; Losick, R, ed. Bacillus Subtilis and Other Gram-positive Bacteria. Washington,D.C: American Society for Microbiology, 1993, pp.645-650.
• Partridge SR, Errington J. The importance of morphological events and intercellular interactions in the regulation of prespore-specific gene expression during sporulation in Bacillus subtilis. Molecular Microbiology 1993, 8(5), 945-955.
• Errington J. Bacillus subtilis sporulation: a paradigm for the spatial and temporal control of gene expression. In: Russo, EVA; Brody, S; Cove, D; Ottolenghi, S, ed. Development: The Molecular Genetic Approach. Heidelberg: Springer-Verlag, 1992, pp.28-44.
• Gibson RM, Errington J. A novel Bacillus subtilis expression vector based on bacteriophage φ105. Gene 1992, 121(1), 137-142.
• Stevens CM, Daniel R, Illing N, Errington J. Characterization of a sporulation gene, spoIVA, involved in spore coat morphogenesis in Bacillus subtilis. Journal of Bacteriology 1992, 174(2), 586-594.
• Errington J, Illing N. Establishment of cell-specific transcription during sporulation in Bacillus subtilis. Molecular Microbiology 1992, 6(6), 689-695.
• Errington J, Appleby L, Daniel RA, Goodfellow H, Partridge SR, Yudkin MD. Structure and function of the spoIIIJ gene of Bacillus subtilis: a vegetatively expressed gene that is essential for σ^G activity at an intermediate stage of sporulation. Journal of General Microbiology 1992, 138(12), 2609-2618.
• Errington J. Unpublished results (originally spoVAF work). 1992.
• Errington J. A model for asymmetric septum formation during sporulation in Bacillus subtilis. Molecular Microbiology 1991, 5(4), 785-789.
• Errington J, Wake RG. Chromosome strand segregation during sporulation in Bacillus subtilis. Molecular Microbiology 1991, 5(5), 1145-1149.
• Illing N, Errington J. Genetic regulation of morphogenesis in Bacillus subtilis: roles of σ^E and σ^F in prespore engulfment. Journal of Bacteriology 1991, 173(10), 3159-3169.
• Errington J. Possible intermediate steps in the evolution of a prokaryotic developmental system. Proceedings of the Royal Society of London B: Biological Sciences 1991, 244(1310), 117-121.
• Foulger D, Errington J. Sequential activation of dual promoters by different sigma factors maintains spoVJ expression during successive developmental stages of Bacillus subtilis. Molecular Microbiology 1991, 5(6), 1363-1373.
• Mysliwiec TH, Errington J, Vaidya AB, Bramucci MG. The Bacillus subtilis spo0J gene: evidence for involvement in catabolite repression of sporulation. Journal of Bacteriology 1991, 173(6), 1911-1919.
• Partridge SR, Foulger D, Errington J. The role of σ^F in prespore-specific transcription in Bacillus subtilis. Molecular Microbiology 1991, 5(3), 757-767.
• Illing N, Errington J. The spoIIIA operon of Bacillus subtilis defines a new temporal class of mother-cell-specific sporulation genes under the control of the σ^E form of RNA polymerase. Molecular Microbiology 1991, 5(8), 1927-1940.
• East AK, Errington J. Unpublished results. 1991.
• Thornewell SJ, Errington J. Unpublished results. 1991.
• Stevens CM, Errington J. Differential gene expression during sporulation in Bacillus subtilis: structure and regulation of the spoIIID gene. Molecular Microbiology 1990, 40(4), 543-551.
• Errington J. Gene cloning techniques. In: Harwood, CR; Cutting, SM, ed. Molecular Biological Methods for Bacillus. Chichester, U.K: Wiley, 1990, pp.175-220.
• Errington J, Mountain A. Is Bacillus an alternative expression system?. In: Harris, TJR, ed. Protein Production by Biotechnology. London: Elsevier, 1990, pp.1-15.
• Errington J, Vogt CH. Isolation and characterization of mutations in the gene encoding an endogenous Bacillus subtilis β-galactosidase and its regulator. Journal of Bacteriology 1990, 172(1), 488-490.
• Errington J, Foulger D, Illing N, Partridge SR, Stevens CM. Regulation of differential gene expression during sporulation in Bacillus subtilis. In: Zukowski, MM; Ganesan, AT; Hoch, JA, ed. Genetics and Biotechnology of Bacilli. San Diego: Academic Press, 1990, pp.257-267.
• Errington J. Regulation of gene expression during sporulation in Bacillus subtilis. In: Genetics of Industrial Microorganisms: Proceedings of the Sixth International Symposium, vol. II. 1990, Strasbourg: Paris: Societe Francaise de Microbiologie.
• Illing N, Errington J. The spoIIIA locus is not a major determinant of prespore-specific gene expression during sporulation in Bacillus subtilis. Journal of Bacteriology 1990, 172(12), 6930-6936.
• Illing N, Young M, Errington J. Use of integrational plasmid excision to identify cellular localization of gene expression during sporulation in Bacillus subtilis. Journal of Bacteriology 1990, 172(12), 6937-6941.
• East AK, Errington J. A new bacteriophage vector for cloning in Bacillus subtilis and the use of φ105 for protein synthesis in maxicells. Gene 1989, 81(1), 35-43.
• Errington J, Wootten L, Dunkerley JC, Foulger D. Differential gene expression during sporulation in Bacillus subtilis: regulation of the spoVJ gene. Molecular Microbiology 1989, 3(8), 1053-1060.
• Foulger D, Errington J. The role of the sporulation gene spoIIIE in the regulation of prespore-specific gene expression in Bacillus subtilis. Molecular Microbiology 1989, 3(9), 1247-1255.
• Errington J, Cutting SM, Mandelstam J. Branched pattern of regulatory interactions between late sporulation genes in Bacillus subtilis. Journal of Bacteriology 1988, 170(2), 796-801.
• Errington J. Generalized cloning vectors for Bacillus subtilis. In: Rodriguez, RL; Denhardt, DT, ed. Vectors: A Survey of Molecular Cloning Vectors and Their Uses. Boston: Butterworths, 1988, pp.345-362.
• Losick R, Kroos L, Errington J, Youngman P. Pathways of developmentally regulated gene expression in the spore-forming bacterium Bacillus subtilis. In: Hopwood, DA; Chater, KF, ed. Genetics of Bacterial Diversity. London: Academic Press, 1988, pp.221-242.
• Errington J. Regulation of sporulation. Nature 1988, 333(6172), 399-400.
• Errington J, Mandelstam J. Regulatory interactions between the spo genes. In: Ganesan, AT; Hoch, JA; Joch JA, ed. Genetics and Biotechnology of Bacilli. San Diego: Academic Press Inc, 1988, pp.147-150.
• Errington J, Rong S, Rosenkrantz MS, Sonenshein AL. Transcriptional regulation and structure of the Bacillus subtilis sporulation locus spoIIIC. Journal of Bacteriology 1988, 170(3), 1162-1167.
• Errington J, Jones D. Cloning in Bacillus subtilis by transfection with bacteriophage vector φ105J27: isolation and preliminary characterization of transducing phages for 23 sporulation loci. Journal of General Microbiology 1987, 133(3), 493-502.
• Jones D, Errington J. Construction of improved bacteriophage φ105 vectors for cloning by transfection in Bacillus subtilis. Journal of General Microbiology 1987, 133(3), 483-492.
• Mandelstam J, Errington J. Dependent sequences of gene expression controlling spore formation in Bacillus subtilis. Microbiological Sciences 1987, 4(8), 238-244.
• Errington J. Hypothesis: two separable domains in the s-subunit of RNA polymerase in Bacillus subtilis?. FEBS Letters 1987, 224(2), 257-260.
• Errington J. New vectors for gene cloning in Bacillus subtilis. In: Proceedings of the Fifth International Symposium on the Genetics of Industrial Microorganisms. 1987, Split, Croatia: Karlovac, Yugoslavia: Ognjen Prica Printing Works.
• Errington J, Pughe N. Upper limit for DNA packaging by Bacillus subtilis bacteriophage φ105: isolation of phage deletion mutants by induction of oversize prophages. Molecular and General Genetics 1987, 210(2), 347-351.
• Errington J. A general method for fusion of the Escherichia coli lacZ gene to chromosomal genes in Bacillus subtilis. Journal of General Microbiology 1986, 132(11), 2953-2966.
• Errington J. Gene cloning and expression vectors based on Bacillus subtilis bacteriophage φ105. In: Ganesan, AT; Hoch, JA, ed. Bacillus Molecular Genetics and Biotechnology Applications. Orlando, Florida: Academic Press Inc, 1986, pp.217-227.
• Errington J, Mandelstam J. Use of a lacZ gene fusion to determine the dependence pattern of sporulation operon spoIIA in spo mutants of Bacillus subtilis. Journal of General Microbiology 1986, 132, 2967-2976.
• Turner SM, Errington J, Mandelstam J. Use of a lacZ gene fusion to determine the dependence pattern of sporulation operon spoIIIC in spo mutants of Bacillus subtilis: a branched pathway of expression of sporulation operons. Journal of General Microbiology 1986, 132(11), 2995-3003.
• Errington J, Fort P, Mandelstam J. Duplicated sporulation genes in bacteria: implications for simple developmental systems. FEBS Letters 1985, 188(2), 184-188.
• Fort P, Errington J. Nucleotide sequence and complementation analysis of a polycistronic sporulation operon, spoVA, in Bacillus subtilis. Journal of General Microbiology 1985, 131(5), 1091-1105.
• Errington J. Efficient Bacillus subtilis cloning system using bacteriophage vector σ105J9. Journal of General Microbiology 1984, 130(10), 2615-2628.
• Errington J, Mandelstam J. Genetic and phenotypic characterization of a cluster of mutations in the spoVA locus of Bacillus subtilis. Journal of General Microbiology 1984, 130(8), 2115-2121.
• Bugaichuk UD, Deadman M, Errington J, Savva D. Restriction enzyme analysis of Bacillus subtilis bacteriophage φ105 DNA. Journal of General Microbiology 1984, 130(8), 2165-2167.
• Vivian A, Errington J, Veal D. The genetics of the cherry pathogen Pseudomonas syringae pathovar morsprunorum. In: Proceedings of the 1st International Symposium on the Molecular Genetics of Bacteria-Plant Interactions. 1983, Bielefeld: Berlin: Springer-Verlag.
• Errington J, Mandelstam J. Variety of sporulation phenotypes resulting from mutations in a single regulatory locus, spoIIA, in Bacillus subtilis. Journal of General Microbiology 1983, 129(7), 2091-2101.
• Errington J, Vivian A. An indigenous system of gene transfer in the plant pathogen Pseudomonas morsprunorum. Journal of General Microbiology 1981, 124(2), 439-442.