• Cell morphogenesis in Bacillus subtilis: from genetics to exploitation (£3,201,603)
  Principal Investigator: Professor Jeff Errington
• Regulation of elongation by RNA polymerase and ribosome via intrinsic signals and transcription-translation coupling (£692,381)
  Principal Investigator: Professor Nikolay Zenkin
• Role of transcriptional fidelity and processivity on the noise of transcription, and its consequences for phenotypic bistability in Streptococcus pneumoniae (£360,558)
  Principal Investigator: Professor Nikolay Zenkin
• Assembly of the bacterial DNA replication initiation complex (£14951)
  Principal Investigator: Dr Heath Murray
• B. subtilis cell wall synthesis (£501,033)
  Principal Investigator: Professor Waldemar Vollmer
• Regulation of peptidoglycan synthesis  (£551,866)
  Principal Investigator: Professor Waldemar Vollmer
• Phosphotransferases in cell wall synthesis  (£363,399)
  Principal Investigator: Professor Waldemar Vollmer
• A synthetic biology approach to enhanced lignocellulose degradation in the biobutanol organism Clostridium acetobutylicum (£671,288)
  Principal Investigator: Professor David Bolam
• The use of genome mining and protein engineering to generate novel xylan and cellulose degrading enzymes (£445,000)
  Principal Investigator: Professor Harry Gilbert
• Engineering enzymes, bacteria and bioconversion processes for advanced biofuels from waste grain straw (£405,000)
  Principal Investigator: Professor Harry Gilbert

• Evolutionary Optimisation of Self Assembling Nano-Designs (£945,423)
  Principal Investigator: Professor Natalio Krasnogor
• Towards a Universal Biological-Cell Operating System (£1,026,408)
  Principal Investigator: Professor Natalio Krasnogor
• ROADBLOCK: Towards Programmable Defensive Bacterial Coatings & Skins (£791,388)
  Principal Investigator: Professor Natalio Krasnogor
• TAURUS: towards an audacious universal constructor (£252,781) 
  Principal Investigator: Professor Natalio Krasnogor
• FLOWERS An Infrastructure for platform technology in synthetic biology (£819,605) 
  Principal Investigators: Professor Anil Wipat, Professor Colin Harwood, Professor Jeff Errington
• SynbiCITE - an Imperial College led Innovation and Knowledge Centre (IKC) in Synthetic Biology (£6,237,589)
• Principal Investigators: Professor Anil Wipat, Professor Colin Harwood, Professor Jeff Errington
• A New Frontier in Design: The Simulation of Open Engineered Biological Systems (£5,557,007) 
  Principal Investigator: Professor Anil Wipat
• Early-Warning Sensing Systems for Infectious Diseases (£11.1m) 
  Principal Investigator: Professor Calum McNeil
• The Multi-Corder (£3.4m) 
  Principal Investigator: Dr Neil Keegan
• High Frequency Degenerate Mode Acoustic Sensors (DSAW) (£778,000) 
  Principal Investigator: Dr John Hedley

• CADMAD: Paving the Way for Future Emerging DNA-based Technologies: Computer-Aided Design and Manufacturing of DNA libraries (£3,229,552) 
  Principal Investigator: Professor Natalio Krasnogor
• Kill*Spill: Integrated Biotechnological  Solutions for Combating Marine Oil Spills (£260,000) 
  Principal Investigator: Professor Ian Head
• Origins, proliferation and pathogenesis of L-form bacteria (OPAL) (£1,560,684) 
  Principal Investigator: Professor Jeff Errington
• Identification and characterization of factors involved in chromosome organization and septuum positoning in bacteria (COSP) (£143,122) 
  Principal Investigator: Professor Jeff Errington
• ICT-Enabled, Cellular Artificial Liver System Incorporating Personalized Patient Management and Support (d-LIVER) Large Scale Integrating Project  (€10.96M) 
  Principal Investigator: Professor Calum McNeil
• Marie-Curie Initial Training Network project on pectin biodegradation ‘WALLTRAC’ (£190000)
  Principal Investigator: Professor Harry Gilbert
• Exploiting complex glycan metabolism in the human microbiota ( £1,779,213)
• Principal Investigator: Professor Harry Gilbert

Understanding the mechanisms of CFS/ME (£451,573) 
Principal Investigator: Professor Anil Wipat

• OILSPORE: Spore-forming hydrocarbon degraders and thermophiles, dispersal from petroleum reservoirs, and a test of the palaeopasteurization hypothesis (£445,000) 
  Principal Investigator: Professor Ian Head
• Resource recovery from wastewater with Bioelectrochemical Systems (£67,000) 
  Principal Investigator: Professor Ian Head

METAMORPHE; Metagenomic analysis and microbially relevant processes in hydrocarbon environments (£145,000)
Principal Investigator: Professor Ian Head

Feasibility study on application of synthetic biology approaches to high yield production of Mycosporine-like amino acids for use as UV-protectants (£248,000)
Principal Investigators: Professor Anil Wipat, Professor Colin Harwood, Professor Jeff Errington

Engineering CAM photosynthetic machinery into bioenergy crops for biofuels production in marginal environments ( $14.3m) 
Principal Investigator: Professor Anne Borland

• Chromosome segregation and cytokinesis in bacteria: mechanism and regulation (£1,531,972)
  Principal Investigator: Professor Jeff Errington
• Understanding the contribution of the human microbiota to human health ( £1,487,774)
  Principal Investigator: Professor Harry Gilbert