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Arthritis Research UK Tissue Engineering Centre

The centre brings together leading clinicians, engineers and biologists from research and clinical groups.

Project leader

Professor AW McCaskie

Dates

April 2011 to April 2016

Project staff

Dr XN Wang

Professor KW Dalgarno

Professor AM Dickinson

Dr MA Birch

Sponsors

Arthritis Research UK

Partners

University of Aberdeen

Keele University

The Robert Jones and Agnes Hunt Hospital

NHS Foundation Trust, Oswestry

University of York

Description

Research at the Centre focuses on:

  • Assessment of the immunogenicity of the stem cells from the same and a different donor. Also their interaction with new biomaterials for regenerative use.
  • Enabling the technologies to be translational to the clinic. Through the use of Good Manufacturing Practices (GMP) in their dedicated facilities.
  • Investigating the manufacture of 3D matrices to support bone and cartilage regeneration. Using special biomaterials which will slowly dissolve in the body as the natural tissue grows. 
    • The team engineered new scaffold materials.
    • They fulfilled the mechanical demands of tissue replacement surgery.
    • They devised approaches to deliver chemical or growth factor cues that can control the rebuilding of bone and cartilage.
  • Working towards clinical translation and surgical therapies.
Undergraduate
Postgraduate Research
Postgraduate Taught