Staff Profile
Dr Piergiorgio Gentile
Reader in Bionanotechnologies
- Telephone: 0191 208 3620
- Address: School of Engineering
Room M10, Stephenson Building
Newcastle University
Newcastle upon Tyne
NE1 7RU
I completed my undergraduate degrees in Biomedical Engineering at the Politecnico di Torino (Italy) in 2006. From January 2007 to December 2009, I was a PhD student in Biomedical Engineering at the Department of Mechanics, Politecnico di Torino, where I worked on the improvement of the bioactivity of membranes or porous scaffolds for bone-tissue engineering applications. After two years as PostDoc researcher in the Industrial Bioengineering Group at Politecnico di Torino, I moved in 2012 at the University of Sheffield, awarded with an IEF Marie Curie Fellowship (2012-2014) and then I worked as PostDoc research fellow within the MeDe Innovation project for one year.
I joined the School of Mechanical and Systems Engineering at Newcastle University in September 2015 as Lecturer. Currently, I am also CEO of Geltis srl, a spin-out company of Politecnico di Torino, that is involved in the synthesis of biodegradable polymers for drug delivery and tissue engineering.
Awards:
November 2017: "Santander" mobility award
July 2016: “Larry Hench” Young Investigator award by UK Society of Biomaterials (UKSB)
June 2015: Award for "Best oral presentation" at SIB (Societa' Italiana dei Biomateriali) congress
October 2011: Grant “Generazione impresa” provided by I3P - Innovative Enterprise Incubator of Politecnico di Torino, Italy to follow the constitution of Geltis srl.
September 2010: “Alberto Mazzoldi” award by Italian National Bioengineering Group (GNB) for the PhD dissertation.
My scientific background is related to the design, processing and characterisation of biomedical materials (natural and synthetic polymers, ceramics, and composites), aiming to nano- and micro- scale design and manufacturing of biomimetic and innovative medical devices for Tissue Engineering and Regenerative Medicine.
To date I have published 46 papers peer-reviewed papers (h-index without self-citations = 26 with more than 2200 citations, Scopus source) in the leading journals in Biomaterials and Regenerative medicine field, including 17 as first author and 6 last-author and 4 book chapter, along with 3 patents. In addition, I have undertaken a six month period of research in the laboratories of Prof Rui Reis in Portugal. My research has led to 18 oral presentations at international meetings and conferences, and the quality of my research has been further recognised with a special prize for my PhD thesis, the award of a Marie Curie Fellowship and, recently, I have been awarded with the “Larry Hench” Young Investigator prize by UK Society of Biomaterials (UKSB)
Furthermore, during my PhD and postdoctoral period, I provided collaborations with (1) Italian scientists: Prof. Elvira DeGiglio, University of Bari, Prof. Monica Mattioli-Belmonte from the Università Politecnica delle Marche; and (2) international scientist: Prof. George Georgiev from the University of Sofia, Bulgaria, Prof. Rui L. Reis of the 3B´s Research Group of University of Minho, Prof. Zeibun Ramtoola of the Royal College of Surgeons in Ireland, Dr Deepak Kalaskar from UCL and Dr Gianni Soldati from Swiss Stem Cell Foundation.
Taught Modules
- MEC1007: Fundamentals of Thermofluid Dynamics
- MEC2008: Mechanical Engineering Professionals Skills II
- MEC8051: Biomedical Additive Manufacture and Biofabrication
- MEC8052: Manufacturing, Materials and Processes
Student Projects
Stage 3:
- MEC3018: Design for industry
- MEC3098: Individual Projects
Stage 4:
- MEC3098: Individual Projects
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Articles
- Desmond L, Margini S, Barchiesi E, Pontrelli G, Phan AN, Gentile P. Layer-by-layer assembly of nanotheranostic particles for simultaneous delivery of docetaxel and doxorubicin to target osteosarcoma. APL Bioengineering 2024, 8(1), 016113.
- Giron-Hernandez J, Tombe A, Chemban Koyilot M, Salas-Calderon KT, Charlton A, Wills C, Gentile P. From cocoa waste to sustainable bioink: valorising pectin for circular economy-driven tissue engineering. European Polymer Journal 2024, 210, 112967.
- Giron-Hernandez J, Rodriguez YB, Corbezzolo N, Blanco DO, Gutierrez CC, Cheung W, Gentile P. Exploiting residual cocoa biomass to extract advanced materials as building blocks for manufacturing nanoparticles aimed at alleviating formation-induced oxidative stress on human dermal fibroblasts. Nanoscale Advances 2024, 15(6), 3809-3824.
- Cometa S, Busto F, Scalia AC, Castellaneta A, Gentile P, Cochis A, Manfredi M, Borrini V, Rimondini L, De Giglio E. Effectiveness of gellan gum scaffolds loaded with Boswellia serrata extract for in-situ modulation of pro-inflammatory pathways affecting cartilage healing. International Journal of Biological Macromolecules 2024, 277(Part 1), 134079.
- Udduttula A, Jakubovics N, Khan I, Pontiroli L, Rankin KS, Gentile P, Ferreira AM. Layer-by-Layer Coatings of Collagen-Hyaluronic acid Loaded with an Antibacterial Manuka Honey Bioactive Compound to Fight Metallic Implant Infections. ACS Applied Materials and Interfaces 2023, 15(50), 58119-58135.
- Giron-Hernandez J, Pazmino M, Barrios-Rodriguez YF, Turo CT, Wills C, Cucinotta F, Benlloch-Tinoco M, Gentile P. Exploring the effect of utilising organic acid solutions in ultrasound-assisted extraction of pectin from apple pomace, and its potential for biomedical purposes. Heliyon 2023, 9(7), e17736.
- Ugurluoglu YF, Ferreira AM, Gentile P, Munguia J. Conceptual design and development of a progressive cavity pump for extrusion-based additive manufacturing applications. CIRP Journal of Manufacturing Science and Technology 2023, 46, 191-203.
- Kotlarz M, Melo P, Ferreira AM, Gentile P, Dalgarno K. Cell seeding via bioprinted hydrogels supports cell migration into porous apatite-wollastonite bioceramic scaffolds for bone tissue engineering. Biomaterials Advances 2023, 153, 213532.
- Hojat N, Gentile P, Ferreira AM, Siller L. Automatic pore size measurements from scanning electron microscopy images of porous scaffolds. Journal of Porous Materials 2023, 30, 93-101.
- Scalzone A, Cerqueni G, Wang XN, Dalgarno K, Mattioli-Belmonte M, Ferreira-Duarte AM, Gentile P. A cytokine-induced spheroid-based in vitro model for studying osteoarthritis pathogenesis. Frontiers in Bioengineering and Biotechnology 2023, 11, 1167623.
- Naseem R, Montalbano G, German MJ, Ferreira AM, Gentile P, Dalgarno K. Influence of PCL and PHBV on PLLA Thermal and Mechanical Properties in Binary and Ternary Polymer Blends. Molecules 2022, 27(21), 7633.
- Cortes-Macias ET, Lopez CF, Gentile P, Giron-Hernandez J, Lopez AF. Impact of post-harvest treatments on physicochemical and sensory characteristics of coffee beans in Huila, Colombia. Postharvest Biology and Technology 2022, 187, 111852.
- Kotlarz M, Ferreira AM, Gentile P, Russell SJ, Dalgarno K. Droplet-based bioprinting enables the fabrication of cell-hydrogel-microfibre composite tissue precursors. Bio-Design and Manufacture 2022, 5, 512-528.
- Barchiesi E, Wareing T, Desmond L, Phan AN, Gentile P, Pontrelli G. Characterization of the Shells in Layer-By-Layer Nanofunctionalized Particles: A Computational Study. Frontiers in Bioengineering and Biotechnology 2022, 10, 888944.
- Kotlarz M, Ferreira AM, Gentile P, Dalgarno K. Bioprinting of cell-laden hydrogels onto titanium alloy surfaces to produce a bioactive interface. Macromolecular Bioscience 2022, 22(6), 2200071.
- Scalzone A, Cerqueni G, Wang X-N, Ferreira-Duarte A, Dalgarno K, Mattioli-Belmonte M, Gentile P. An In Vitro Engineered Osteochondral Model as Tool to Study Osteoarthritis Environment. Advanced Healthcare Materials 2022, 12(2), 2202030.
- Udduttula A, Li J, Ma Z, Teng B, Zhang JV, Ferreira AM, Gentile P, Wang G, Zhao X, Ren P-G. A novel apatite-inspired Sr5(PO4)2SiO4 plasma-sprayed coating on Ti alloy promoting biomineralization, osteogenesis and angiogenesis. Ceramics International 2022, 48(8), 10979-10989.
- Scalzone A, Wang XN, Dalgarno K, Ferreira AM, Gentile P. A Chondrosphere-Based Scaffold Free Approach to Manufacture an In Vitro Articular Cartilage Model. Tissue Engineering Part A 2022, 28(1-2), 84-93.
- Bonifacio MA, Cometa S, Cochis A, Scalzone A, Gentile P, Scalia AC, Rimondini L, Mastrorilli P, De Giglio E. A bioprintable gellan gum/lignin hydrogel: a smart and sustainable route for cartilage regeneration. International Journal of Biological Macromolecules 2022, 216, 336-346.
- Naseem R, Tzivelekis C, German MJ, Gentile P, Ferreira-Duarte A, Dalgarno K. Strategies for Enhancing Polyester-Based Materials for Bone Fixation Applications. Molecules 2021, 26(4), 992.
- Harrison CJ, Hatton PV, Gentile P, Miller CA. Nanoscale strontium-substituted hydroxyapatite pastes and gels for bone tissue regeneration. Nanomaterials 2021, 11(6), 1611.
- Dudman J, Ferreira AM, Gentile P, Wang X, Dalgarno K. Microvalve Bioprinting of MSC-Chondrocyte Co-Cultures. Cells 2021, 10(12), 3329.
- Giron-Hernandez J, Gentile P, Benlloch-Tinoco M. Impact of heterogeneously crosslinked calcium alginate networks on the encapsulation of β-carotene-loaded beads. Carbohydrate Polymers 2021, 271, 118429.
- Ugurluoglu YF, Gentile P, Ferreira-Duarte A, Munguia J. Effect of process parameters of the positive displacement pump for extrusion based bioprinting application. Journal of Additive Manufacturing Technologies 2021, 1(2), 560.
- Dudman J, Ferreira AM, Gentile P, Wang XN, Ribeiro R, Benning M, Dalgarno K. Reliable inkjet printing of chondrocytes and MSCs using reservoir agitation. Biofabrication 2020, 12(4), 045024.
- Melo P, Naseem R, Corvaglia I, Montalbano G, Pontremoli C, Azevedo A, Quadros P, Gentile P, Ferreira AM, Dalgarno K, Vitale-Brovarone C, Fiorilli S. Processing of Sr2+ containing Poly L-Lactic Acid-based hybrid composites for additive manufacturing of bone scaffolds. Frontiers in Materials 2020, 7, 601645.
- Carmagnola I, Chiono V, Ruocco G, Scalzone A, Gentile P, Taddei P, Ciardelli G. Plga membranes functionalized with gelatin through biomimetic mussel-inspired strategy. Nanomaterials 2020, 10(11), 1-17.
- Scalzone A, Bonifacio MA, Cometa S, Cucinotta F, De Giglio E, Ferreira AM, Gentile P. pH-Triggered Adhesiveness and Cohesiveness of Chondroitin Sulfate-Catechol Biopolymer for Biomedical Applications. Frontiers in Bioengineering and Biotechnology 2020, 8, 712.
- Bonifacio MA, Cochis A, Cometa S, Gentile P, Scalzone A, Scalia AC, Rimondini L, De Giglio E. From the sea to the bee: Gellan gum-honey-diatom composite to deliver resveratrol for cartilage regeneration under oxidative stress conditions. Carbohydrate Polymers 2020, 245, 116410.
- Melo P, Kotlarz M, Marshall M, Magallanes M, Ferreira AM, Gentile P, Dalgarno K. Effects of alumina on the thermal processing of apatite-wollastonite: changes in sintering, microstructure and crystallinity of compressed pellets. Journal of the European Ceramic Society 2020, 40(15), 6107-6113.
- Dewhurst RM, Scalzone A, Buckley J, Mattu C, Rankin KS, Gentile P, Ferreira AM. Development of Natural-Based Bone Cement for a Controlled Doxorubicin-Drug Release. Frontiers in Bioengineering and Biotechnology 2020, 8, 754.
- Bonifacio MA, Cochis A, Cometa S, Scalzone A, Gentile P, Procino G, Milano S, Scalia AC, Rimondini L, De Giglio E. Advances in cartilage repair: The influence of inorganic clays to improve mechanical and healing properties of antibacterial Gellan gum-Manuka honey hydrogels. Materials Science and Engineering: C 2020, 108, 110444.
- Pierantozzi D, Scalzone A, Jindal S, Stipniece L, Salma-Ancane K, Dalgarno K, Gentile P, Mancuso E. 3D printed Sr-containing composite scaffolds: Effect of structural design and material formulation towards new strategies for bone tissue engineering. Composites Science and Technology 2020, 191, 108069.
- Scalzone A, Ferreira AM, Tonda-Turo C, Ciardelli G, Dalgarno K, Gentile P. The interplay between chondrocyte spheroids and mesenchymal stem cells boosts cartilage regeneration within a 3D natural-based hydrogel. Scientific Reports 2019, 9(1), 14630.
- Melo P, Tarrant E, Swift T, Townshend A, German M, Ferreira AM, Gentile P, Dalgarno K. Short phosphate glass fiber - PLLA composite to promote bone mineralization. Materials Science and Engineering C 2019, 104, 109929.
- Mancuso E, Tonda-Turo C, Ceresa C, Pensabene V, Connell SD, Fracchia L, Gentile P. Potential of Manuka Honey as a natural polyelectrolyte to develop biomimetic nanostructured meshes with antimicrobial properties. Frontiers in Bioengineering and Biotechnology 2019, 7, 344.
- Melo P, Ferreira A-M, Waldron K, Swift T, Gentile P, Magallanes M, Marshall M, Dalgarno K. Osteoinduction of 3D printed particulate and short-fibre reinforced composites produced using PLLA and apatite-wollastonite. Composites Science and Technology 2019, 184, 107834.
- Caddeo S, Mattioli-Belmonte M, Cassino C, Barbani N, Dicarlo M, Gentile P, Baino F, Sartori S, Vitale-Brovarone C, Ciardelli G. Newly-designed collagen/polyurethane bioartificial blend as coating on bioactive glass-ceramics for bone tissue engineering applications. Materials Science and Engineering C 2019, 96, 218-233.
- Boido M, Ghibaudi M, Gentile P, Favaro E, Fusaro R, Tonda-Turo C. Chitosan-based hydrogel to support the paracrine activity of mesenchymal stem cells in spinal cord injury treatment. Scientific Reports 2019, 9(1), 6402.
- McColgan-Bannon KIS, Upson S, Gentile P, Tausif M, Russell S, Dalgarno K, Ferreira AM. Biomimetic Properties of Force-Spun PHBV Membranes Functionalised with Collagen as Substrates for Biomedical Application. Coatings 2019, 9(6), 350.
- Dura G, Waller H, Gentile P, Lakey JH, Fulton DA. Tuneable hydrogels of Caf1 protein fibers. Materials Science and Engineering C 2018, 93, 88-95.
- Ribeiro R, Pal D, Ferreira AM, Gentile PG, Benning M, Dalgarno K. Reactive jet impingement bioprinting of high cell density gels for bone microtissue fabrication. Biofabrication 2018, 11(1), 015014.
- Tonda-Turo C, Ruini F, Ceresa C, Gentile P, Varela P, Ferreira AM, Fracchia L, Ciardelli G. Nanostructured scaffold with biomimetic and antibacterial properties for wound healing produced by 'green electrospinning'. Colloids and Surfaces B: Biointerfaces 2018, 172, 233-243.
- De Giglio E, Bonifacio MA, Ferreira AM, Cometa S, Ti ZY, Stanzione A, Dalgarno K, Gentile P. Multi-compartment scaffold fabricated via 3D-printing as in vitro co-culture osteogenic model. Scientific reports 2018, 8(1), 15130.
- Etxabide A, Ribeiro RDC, Guerrero P, Ferreira AM, Stafford GP, Dalgarno K, de la Caba K, Gentile P. Lactose-crosslinked fish gelatin-based porous scaffolds embedded with tetrahydrocurcumin for cartilage regeneration. International Journal of Biological Macromolecules 2018, 117, 199-208.
- Bonifacio MA, Cometa S, Cochis A, Gentile P, Ferreira AM, Azzimonti B, Procino G, Ceci E, Rimondini L, De Giglio E. Data on Manuka Honey/Gellan Gum composite hydrogels for cartilage repair. Data in Brief 2018, 20, 831-839.
- Salam N, Toumpaniari S, Gentile P, Ferreira AM, Dalgarno K, Partridge S. Assessment of Migration of Human MSCs through Fibrin Hydrogels as a Tool for Formulation Optimisation. Materials 2018, 11(9), 1781.
- Bonifacio MA, Cometa S, Cochis A, Gentile P, Ferreira AM, Azzimonti B, Procino G, Ceci E, Rimondini L, DeGiglio E. Antibacterial effectiveness meets improved mechanical properties: Manuka Honey/Gellan Gum composite hydrogels for cartilage repair. Carbohydrate Polymers 2018, 198, 462–472.
- Fernandes JS, Gentile P, Crawford A, Pires RA, Hatton PV, Reis RV. Substituted Borosilicate Glasses with Improved Osteogenic Capacity for Bone Tissue Engineering. Tissue Engineering Part A 2017, 23(23-24), 1331-1342.
- Wilcock C, Gentile P, Hatton PV, Miller CA. Rapid Mix Preparation of Bioinspired Nanoscale Hydroxyapatite for Biomedical Applications. Journal of Visualized Experiments 2017, (120), e55343.
- Tonda-Turo C, Ruini F, Ramella M, Boccafoschi F, Gentile P, Gioffredi E, Falvo D'Urso Labate G. Non-covalently crosslinked chitosan nanofibrous mats prepared by electrospinning as substrates for soft tissue regeneration. Carbohydrate Polymers 2017, 162, 82-92.
- Gentile P, Ferreira AM, Callaghan JT, Miller CA, Atkinson J, Freeman C, Hatton PV. Multilayer Nanoscale Encapsulation of Biofunctional Peptides to Enhance Bone Tissue Regeneration In Vivo. Advanced Healthcare Materials 2017, 6(8), 1601182.
- Bonifacio MA, Gentile PG, Ferreira AM, Cometa S, Giglio ED. Insight into halloysite nanotubes-loaded gellan gum hydrogels for soft tissue engineering applications. Carbohydrate Polymers 2017, 163, 280-291.
- Gentile P, McColgan-Bannon K, Ceretto N, Sefat F, Dalgarno K, Ferreira AM. Biosynthetic PCL-graft-collagen bulk material for tissue engineering. Materials 2017, 10(7), 693-710.
- Gentile P, Ghione C, Ferreira AM, Crawford A, Hatton PV. Alginate-based Hydrogels Functionalised at the Nanoscale using Layer-by-Layer Assembly for Potential Cartilage Repair. Biomaterials Science 2017, 5(9), 1922-1931.
- Fernandes JS, Gentile P, Martinsa M, Nevesa NM, Miller C, Crawford A, Pires RA, Hatton PH, Reis RL. Reinforcement of poly-L-lactic acid electrospun membranes with strontium borosilicate bioactive glasses for bone tissue engineering. Acta Biomaterialia 2016, 44, 168-177.
- Nardo T, Chiono V, Gentile P, Tabrizian M, Ciardelli G. Poly(DL-lactide-co-ε-caprolactone) and poly(DL-lactide-co-glycolide) blends for biomedical application: Physical properties, cell compatibility, and in vitro degradation behavior. International Journal of Polymetric Materials and Polymetric Biomaterials 2016, 65(14), 741-750.
- Chandrasekaran A, Novajra G, Carmagnola I, Gentile P, Fiorilli S, Miola M, Boregowda M, Dakshanamoorthy A, Ciardelli G, Vitale-Brovarone C. Physico-chemical and biological studies on three-dimensional porous silk/spray-dried mesoporous bioactive glass scaffolds. Ceramics International 2016, 42(12), 13761-13772.
- Gentile P, Nandagiri VK, Daly J, Chiono V, Mattu C, Tonda-Turo C, Ciardelli G, Ramtoola Z. Localised controlled release of simvastatin from porous chitosan-gelatin scaffolds engrafted with simvastatin loaded PLGA-microparticles for bone tissue engineering application. Materials Science and Engineering C 2016, 59, 249-257.
- Ferreira AM, Gentile P, Toumpaniari S, Ciardelli G, Birch MA. Impact of collagen/heparin multi-layers for regulating bone cellular functions. ACS Applied Materials & Interfaces 2016, 8(44), 29923-29932.
- Tonda-Turo C, Boffito M, Cassino C, Gentile P, Ciardelli G. Biomimetic polyurethane - Based fibrous scaffolds. Materials Letters 2016, 167, 9-12.
- Gentile P, Wilcock CJ, Miller CA, Moorehead R, Hatton PV. Process optimisation to control the physico-chemical characteristics of biomimetic nanoscale hydroxyapatites prepared using wet chemical precipitation. Materials 2015, 8(5), 2297-2310.
- Gentile P, Ghione C, Tonda-Turo C, Kalaskar DM. Peptide functionalisation of nanocomposite polymer for bone tissue engineering using plasma surface polymerisation. RSC Advances 2015, 5(97), 80039-80047.
- Gentile P, Nandagiri VK, Pabari R, Daly J, Tonda-Turo C, Ciardelli G, Ramtoola Z. Influence of Parathyroid Hormone-Loaded PLGA Nanoparticles in Porous Scaffolds for Bone Regeneration. International Journal of Molecular Sciences 2015, 16(9), 20492-20510.
- Gentile P, Frongia ME, Cardellach M, Miller CA, Stafford GP, Leggett GJ, Hatton PV. Functionalised nanoscale coatings using layer-by-layer assembly for imparting antibacterial properties to polylactide-co-glycolide surfaces. Acta Biomaterialia 2015, 21, 35-43.
- Gentile P, Bellucci D, Sola A, Mattu C, Cannillo V, Ciardelli G. Composite scaffolds for controlled drug release: role of the polyurethane nanoparticles on the physical properties and cell behaviour. Journal of the Mechanical Behavior of Biomedical Materials 2015, 44, 53-60.
- Carmagnola I, Nardo T, Gentile P, Tonda-Turo C, Mattu C, Cabodi S, Defilippi P, Chiono V. Poly(lactic acid)-based blends with tailored physicochemical properties for tissue engineering applications: a case study. International Journal of Polymeric Materials and Polymeric Biomaterials 2014, 64(2), 90-98.
- Massai D, Pennella F, Gentile P, Gallo D, Ciardelli G, Bignardi C, Audenino A, Morbiducci U. Image-based three-dimensional analysis to characterize the texture of porous scaffolds. BioMed Research International 2014, 2014, 1-8.
- Ferreira AM, Carmagnola I, Chiono V, Gentile P, Fracchia L, Ceresa C, Georgiev G, Ciardelli G. Surface modification of poly(dimethylsiloxane) by two-step plasma treatment for further grafting with chitosan-Rose Bengal photosensitizer. Surface and Coatings Technology 2013, 223, 92-97.
- Tonda-Turo C, Cipriani E, Gnavi S, Chiono V, Mattu C, Gentile P, Perroteau I, Zanetti M, Ciardelli G. Crosslinked gelatin nanofibres: preparation, characterization and in vitro studies using glial-like cells. Materials Science and Engineering C 2013, 33(5), 2723–2735.
- Ferreira AM, Gentile P, Chiono V, Ciardelli G. Collagen for bone tissue regeneration. Acta Biomaterialia 2012, 8(9), 3191-3200.
- Ferreira AM, Gentile P, Sartori S, Pagliano C, Cabrele C, Chiono V, Ciardelli G. Biomimetic soluble collagen purified from bones. Biotechnology Journal 2012, 7(11), 1386-1394.
- Gentile P, Mattioli-Belmonte M, Chiono V, Ferretti C, Baino F, Tonda-Turo C, Vitale-Brovarone C, Pashkuleva I, Reis RL, Ciardelli G. Bioactive glass/polymer composite scaffolds mimicking bone tissue. Journal of Biomedical Materials Research Part A 2012, 100A(10), 2654-2667.
- Bellucci D, Chiellini F, Ciardelli G, Gazzarri M, Gentile P, Sola A, Cannillo V. Processing and characterization of innovative scaffolds for bone tissue engineering. Journal of Materials Science: Materials in Medicine 2012, 23, 1397–1409.
- Gentile P, Chiono V, Tonda-Turo C, Mattu C, Baino F, Vitale-Brovarone C, Ciardelli G. Bioresorbable glass effect on the physico-chemical properties of bilayered scaffolds for osteochondral regeneration. Materials Letters 2012, 89, 74–76.
- Ferreira AM, Gentile P, Sartori S, Pagliano C, Cabrele C, Chiono V, Ciardelli G. Biomimetic soluble collagen purified from bones. Biotechnology Journal 2012, 7(11), 1386-94.
- Bellucci D, Sola A, Gentile P, Ciardelli G, Cannillo V. Biomimetic coating on bioactive glass-derived scaffolds mimicking bone tissue. Journal of Biomedical Materials Research Part A 2012, 100A(12), 3259–3266.
- TondaTuro C, Audisio C, Gnavi S, Chiono V, Gentile P, Raimondo S, Geuna S, Perroteau I, Ciardelli G. Porous Poly(ε-caprolactone) Nerve Guide Filled with Porous Gelatin Matrix for Nerve Tissue Engineering. Advanced Engineering Materials 2011, 13(5), B151–B164.
- Gentile P, Chiono V, Tonda-Turo C, Ferreira AM, Ciardelli G. Polymeric membranes for guided bone regeneration. Biotechnology Journal 2011, 6(10), 1187-1197.
- Chiono V, Carmagnola I, Gentile I, Boccafoschi F, Tonda-Turo C, Ballarini M, Georgieva V, Georgiev G, Ciardelli G. Layer-by-Layer Coating of Photoactive Polymers for Biomedical Applications. Surface & Coatings Technology 2011, 206, 2446–2453.
- Nandagiri VK, Gentile P, Chiono V, Tonda-Turo C, Matsiko A, Ramtoola Z, Montevecchi FM, Ciardelli G. Incorporation of PLGA nanoparticles into porous chitosan-gelatin scaffolds: influence on the physical properties and cell behaviour. Journal of the Mechanical Behavior of Biomedical Materials 2011, 4(7), 1318–1327.
- Tonda-Turo C, Gentile P, Saracino S, Chiono V, Nandagiri VK, Muzio G, Canuto RA, Ciardelli G. Comparative analysis of gelatin scaffolds crosslinked by genipin and silane coupling agent. International Journal of Biological Macromolecules 2011, 49, 700–706.
- Gentile P, Chiono V, Boccafoschi F, Baino F, Vitale-Brovarone C, Vernè E, Barbani N, Ciardelli G. Composite films of gelatin and hydroxyapatite/bioactive glass for tissue engineering applications. Journal of Biomaterials Science 2010, 8-9, 1207-1226.
- Bellucci D, Cannillo V, Ciardelli G, Gentile P, Sola A. Potassium Based Bioactive Glass for Bone Tissue Engineering. Ceramics International 2010, 36, 2449–2453.
- Chiono V, Gentile P, Boccafoschi F, Carmagnola I, Ninov M, Georgieva V, Georgiev G, Ciardelli G. Photoactive Chitosan Switching on Bone-Like Apatite Deposition. Biomacromolecules 2010, 11(2), 309-315.
- Gentile P, Chiono V, Tonda-Turo C, Sartori S, Ciardelli G. Biomimetic materials for medical application through enzymatic modification. Advances in Biochemical Engineering / Biotechnology 2010, 125, 181-205.
- Nieddu E, Mazzucco L, Gentile P, Benko T, Balbo V, Mandrile R, Ciardelli G. Preparation and biodegradation of clay composites of PLA. Reactive and Functional Polymers 2009, 69(6), 371–379.
- Ciardelli G, Gentile P, Chiono V, Mattioli-Belmonte M, Vozzi G, Barbani N, Giusti P. Enzymatically - Crosslinked Porous Composite Matrices For Bone Tissue Regeneration. Journal of Biomedical Materials Research Part A 2009, 92A(1), 137–151.
- Chiono V, Ciardelli G, Vozzi G, Cortez J, Barbani N, Gentile P, Giusti P. Enzymatically-Modified Melt-Extruded Guides for Peripheral Nerve Repair. Engineering in Life Sciences 2008, 8(3), 226–237.
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Book Chapters
- Scalzone A, Tonda-Turo C, Ferreira AM, Gentile P. 3D-printed Soft Hydrogels for Cell Encapsulation. In: Azevedo HS; Mano JF; Borges J, ed. Soft Matter for Biomedical Applications. Cambridge: Royal Society of Chemistry, 2021, pp.594-625.
- Bazgir M, Hancox Z, Raja T, Gentile P, Ferreira AM, Zhang W, Mozafari M, Katsikogianni M, Youseffi M, Coates P, Sefat F. Scaffolds for blood vessel tissue engineering. In: Mozafari, M; Sefat, F; Atala, A, ed. Handbook of Tissue Engineering Scaffolds: Volume One. Elsevier, 2019, pp.659-684.
- Chiono V, Sartori S, Calzone S, Boffito M, Tonda-Turo C, Mattu C, Gentile P, Ciardelli G. Synthetic biodegradable medical polyurethanes. In: Xiang Zhang, ed. Science and Principles of Biodegradable and Bioresorbable Medical Polymers: Materials and Properties. Duxford: Woodhead Publishing, 2017, pp.189-216.
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Editorials
- Ferreira AM, Gentile P. Editorial: Biofunctional materials and coatings for orthopaedic and dental applications. Frontiers in Bioengineering and Biotechnology 2023, 11, 1203815.
- Gentile P, De Giglio E, Hilborn JG, Ng KW. Editorial: Composite and Functionalized Hydrogels: Implications for Improved and Biological Properties in Tissue Engineering. Frontiers in Bioengineering and Biotechnology 2021, 8, 636575.
- Gentile P, Alarcon EI, Alini M. Editorial: Functionalization at Nanoscale to Enhance Specific Biological Activities. Frontiers in Bioengineering and Biotechnology 2019, 7, 178.
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Reviews
- Rowland S, Aghakhani A, Whalley RD, Ferreira AM, Kotov N, Gentile P. Layer-by-Layer Nanoparticle Assembly for Biomedicine: Mechanisms, Technologies, and Advancement via Acoustofluidics. ACS Applied Nano Materials 2024, 7(14), 15874-15902.
- Medina-Orjuela ME, Barrios-Rodriguez YF, Carranza C, Amorocho-Cruz C, Gentile P, Giron-Hernandez J. Enhancing analysis of neo-formed contaminants in two relevant food global commodities: Coffee and cocoa. Heliyon 2024, 10(10), e31506.
- Benlloch-Tinoco M, Nunez Ramirez JM, Garcia P, Gentile P, Giron-Hernandez J. Theobroma genus: Exploring the therapeutic potential of T. grandiflorum and T. bicolor in biomedicine. Food Bioscience 2024, 61, 104755.
- Barrios-Rodriguez YF, Salas-Calderon KT, Orozco-Blanco DA, Gentile P, Giron-Hernandez J. Cocoa Pod Husk: A High-Pectin Source with Applications in the Food and Biomedical Fields. ChemBioEng Reviews 2022, 9(5), 462-474.
- Carrera-Quintana SC, Gentile P, Giron-Hernandez J. An overview on the aquaculture development in Colombia: Current status, opportunities and challenges. Aquaculture 2022, 561, 738583.
- Bullock G, Atkinson J, Gentile P, Hatton P, Miller C. Osteogenic peptides and attachment methods determine tissue regeneration in modified bone graft substitutes. Journal of Functional Biomaterials 2021, 12(2), 22.
- Cerqueni G, Scalzone A, Licini C, Gentile P, Mattioli-Belmonte M. Insights into oxidative stress in bone tissue and novel challenges for biomaterials. Materials Science and Engineering C 2021, 130, 112433.
- Desmond L, Phan AN, Gentile P. Critical overview on the green synthesis of carbon quantum dots and their application for cancer therapy. Environmental Science: Nano 2021, 8(4), 848-862.
- Ngadimin K, Stokes A, Gentile P, Ferreira AM. Biomimetic hydrogels designed for cartilage tissue engineering. Biomaterials Science 2021, 9(12), 4246-4259.
- Wareing TC, Gentile P, Phan AN. Biomass-Based Carbon Dots: Current Development and Future Perspectives. ACS Nano 2021, 15(10), 15471–15501.
- Cometa S, Bonifacio MA, Ferreira AM, Gentile P, de Giglio E. Surface characterization of electro-assisted titanium implants: A multi-technique approach. Materials 2020, 13(3), 705.
- Sieberath A, Della Bella E, Ferreira AM, Gentile P, Eglin D, Dalgarno K. A Comparison of Osteoblast and Osteoclast In Vitro Co-Culture Models and Their Translation for Preclinical Drug Testing Applications. International Journal of Molecular Sciences 2020, 21(3), 912.
- Ferreira AM, Tonda-Turo C, Mancuso E, Gentile P. Multilayer nanoscale functionalisation to treat disorders and enhance regeneration of bone tissue. Nanomedicine: Nanotechnology, Biology and Medicine 2019, 19, 22-38.
- Longley R, Ferreira AM, Gentile P. Recent approaches to the manufacturing of biomimetic multi-phasic scaffolds for osteochondral regeneration. International Journal of Molecular Sciences 2018, 19(6), 1755.
- Fernandes JS, Gentile P, Pires RA, Reis RL, Hatton PV. Multifunctional bioactive glass and glass-ceramic biomaterials with antibacterial properties for repair and regeneration of bone tissue. Acta Biomaterialia 2017, 59, 2-11.
- Gentile P, Carmagnola I, Nardo T, Chiono V. Layer-by-layer assembly for biomedical applications in the last decade. Nanotechnology 2015, 26(42), 1-21.
- Gentile P, Chiono V, Carmagnola I, Hatton PV. An Overview of Poly(lactic-co-glycolic) Acid (PLGA)-Based Biomaterials for Bone Tissue Engineering. International Journal of Molecular Sciences 2014, 15(3), 3640-3659.