Hasan Merie
Novel bioactive glass for use in dental fillings.
Email: h.merie2@ncl.ac.uk
Project supervisors
- School of Engineering
- School of Dental Sciences
- Iain Evans
Project description
Dental caries is still one of the main cause of tooth cavities and tooth loss. To preserve the dentition, we repair these cavities by filling them with suitable materials. Fluoridated filling materials protect filled teeth from secondary caries.
The materials release fluoride ions. These are then uptaken by the adjacent tooth structure which strengthens and makes it more resistant to caries. Glass-ionomer cements (GICs) are one of the most common class of fluoridated materials able to adhere to the tooth structure. GIC is a simple acid-base reaction between an ion-leachable glass powder (fluoro-aluminosilicate glass) and an aqueous solution of polymeric acid (polyacrylic acid). Bioactive Glass 45S5 (BG) has superior properties and can bond to both soft and hard tissues. Recently, GICs formation has used it with promising results. But the composition of BG does not contain fluoride.
I am developing novel GICs. I am modifying the BG composition with fluoride containing reagents to release a sustainable amount of fluoride.
Interests
Dental materials, tooth filling materials, fluoride releasing glasses, bioactive glasses and dental resin composite.
Qualifications
BDS, MSc and PhD candidate.