Module Catalogue 2025/26

Pre Requisite Comment

N/A

Co Requisite Comment

N/A

Aims

The aim of the module is to introduce microbiological and biochemical concepts relevant to bioprocessing and to provide an overview of the complexity of real chemical systems relevant to successful process development, i.e. conversion of research synthesis into a manufacturing process. The goal is to aid knowledge needed for evaluation of the effect of choices made in developing a synthesis route. Given the growing significance of bioprocessing in providing healthcare, food, water supply solutions as well as the significant sustainability implications of chemical process development, this module is critical for responsible chemical engineering practice.

Outline Of Syllabus

The module will cover scientific aspects of bioprocessing, such as cell structure, enzyme kinetics including immobilised enzymes and metabolic pathways and cell reproduction. Elements of the science of process development will be covered and concepts such as measure of process complexity, chemical reaction modelling, competing reactions, pre-reaction equilibria, multiphase reactions, coupling of chemical and mass transfer rates and scale up, will be exemplified with practical examples.

Intended Knowledge Outcomes

Reference to AHEP4 learning outcomes is shown in brackets. By the end of the course, student will:
1) Apply knowledge of chemistry, biochemistry, microbiology and engineering principles to solve bioprocessing
and complex chemical system challenges (C1);
2) Apply and evaluate appropriate selection criteria for chemical process development, scale-up of multiphase
chemical reaction systems and requirements for manufacturing process, considering applicable health and
safety, sustainability and commercial aspects as well as relevant industry practices (C5, C7).

Intended Skill Outcomes

Ability to correlate knowledge of biochemistry and microbiology with bioprocessing. Ability to correlate theoretical chemical principles to practical process development relevant to process scale-up.

Teaching Rationale And Relationship

The predominance of lectures is appropriate for the module. The tutorial sessions provide an opportunity for the
students to practise the numerical methods required for calculations as well as put taught content into a broader context of a chemical engineering discipline. Throughout the module, students are being prepared for the
assessment and given opportunity to practice each of the elements assessed.

Assessment Rationale And Relationship

The final written exam tests the knowledge of the students on the concepts taught in the lectures. (C1, C5 and C7)

The online quiz and mock exam allow students to determine their learning and assist in their preparation for the summative exam. (C1, C5 and C7).

General Notes

N/A