NES1301 : Molecular Biology of the Cell
NES1301 : Molecular Biology of the Cell
- Offered for Year: 2025/26
- Module Leader(s): Dr James Stach
- Lecturer: Dr Vasilios Andriotis, Dr Maxim Kapralov, Dr Patricia Lopez-Calcagno, Dr Thomas Howard
- Owning School: Natural and Environmental Sciences
- Teaching Location: Newcastle City Campus
Semesters
Your programme is made up of credits, the total differs on programme to programme.
Semester 1 Credit Value: | 20 |
ECTS Credits: | 10.0 |
European Credit Transfer System | |
Pre-requisite
Modules you must have done previously to study this module
Pre Requisite Comment
N/A
Co-Requisite
Modules you need to take at the same time
Co Requisite Comment
N/A
Aims
The module aims to provide a broad introduction to the molecular biology of the cell; workshops will provide free enquiry opportunities. Seminars introduce students to current research in each of the themes to broaden and deepen student knowledge. The assessment challenges students to produce communication materials to enhance the module’s learning aims by researching an area of their choosing within the module themes.
Outline Of Syllabus
The module is organised into 8 themes
1. Evolution of Life
- Origin of life, life without a membrane.
- Cellular evolution - the Prokaryotes, the origin of Eukaryotes
- Tree of Life - History and current basis on molecular evidence
2. Prokaryotes
- Extremophiles – early life and exobiology
- Diversity
3. Viruses
- Structure
- Replication
4. First cells and multicellularity.
- Origin of cells
- Single-celled organisms
5 - 6. Cell structure, function and specialisation
- Structure
- Organisation
- Specialist functions
7 – 8 . Gene expression and control
- Transcription control
- Repression and activation
- Operons
- Eukaryotic gene expression
- Post-translational control
- Non-coding RNAs
9. Protein evolution
- Neutral and positive substitution
- Enzyme function
- microadaptation
10. Molecular mechanism of cell specialisation
- DNA rearrangement
- DNA methylation
- Regulatory circuits
10-12. Genome evolution
- Genome duplication
- Genome reconstitution
- Plant genomes
- Synthetic genomes
13-14. Cell signalling and communication
- Reception
- Transduction
- Response
Learning Outcomes
Intended Knowledge Outcomes
PC1 Knowledge Application (delivered and assessed): Develop fundamental biological knowledge and an awareness of a systems approach. Recognise the broad biological concepts that underpin the discipline (Evolution, Function and specialisation).
Intended Skill Outcomes
On successful completion of the module students should:
PC5 Communication (developed and assessed): Understand, question and communicate biological knowledge and research to a diverse audience; concepts that are within the module themes but go beyond the delivered material will be developed and presented by students.
PC6 Digital Literacy (developed and assessed): Student presentations will have a digital basis. Students will be use animations, data visualisation and media recording to communicate their knowledge.
PC8 Collaborative (developed and assessed): Students will work in groups and have the opportunity to develop initiative, autonomy, and leadership while maintaining responsibility, reliability, accountability, and integrity.
Teaching Methods
Teaching Activities
Category | Activity | Number | Length | Student Hours | Comment |
---|---|---|---|---|---|
Scheduled Learning And Teaching Activities | Lecture | 14 | 1:00 | 14:00 | Present in person with supplementary material available online |
Guided Independent Study | Assessment preparation and completion | 1 | 12:00 | 12:00 | Preparation and Completion of the MCQ Inspera exam and student presentations |
Scheduled Learning And Teaching Activities | Small group teaching | 4 | 1:00 | 4:00 | Seminars present in person with supplementary material available online |
Scheduled Learning And Teaching Activities | Workshops | 5 | 1:00 | 5:00 | Present in person with supplementary material available online |
Guided Independent Study | Independent study | 1 | 165:00 | 165:00 | N/A |
Total | 200:00 |
Teaching Rationale And Relationship
Lectures will provide the framework and theory for appreciation of the molecular biology of the cell and its evolution. Directed reading and links to further information will encourage individual learning and will contribute to greater understanding of the topics within the module. The assessments will provide team-working opportunities and student autonomy in their learning. The intention of the assessment is to help transition students from consumers of information, to researchers and communicators of knowledge.
Reading Lists
Assessment Methods
The format of resits will be determined by the Board of Examiners
Exams
Description | Length | Semester | When Set | Percentage | Comment |
---|---|---|---|---|---|
Digital Examination | 120 | 1 | A | 70 | Inspera MCQ Exam |
Other Assessment
Description | Semester | When Set | Percentage | Comment |
---|---|---|---|---|
Design/Creative proj | 1 | M | 30 | Group digital presentation on student-led area within module themes |
Assessment Rationale And Relationship
The exam will test student understanding of the key module themes. This ensures that the key foundational concepts, which are required throughout their degree, are present and secure. The rationale for presentations is to introduce students early to autonomy in their learning, to demonstrate how to read within and beyond module content and how to communicate professionally with peers and academics.
Timetable
- Timetable Website: www.ncl.ac.uk/timetable/
- NES1301's Timetable
Past Exam Papers
- Exam Papers Online : www.ncl.ac.uk/exam.papers/
- NES1301's past Exam Papers
General Notes
N/A
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Disclaimer
The information contained within the Module Catalogue relates to the 2025 academic year.
In accordance with University Terms and Conditions, the University makes all reasonable efforts to deliver the modules as described.
Modules may be amended on an annual basis to take account of changing staff expertise, developments in the discipline, the requirements of external bodies and partners, staffing changes, and student feedback. Module information for the 2026/27 entry will be published here in early-April 2026. Queries about information in the Module Catalogue should in the first instance be addressed to your School Office.