NES3407 : Advanced Inorganic Chemistry (Distance Learning)
NES3407 : Advanced Inorganic Chemistry (Distance Learning)
- Offered for Year: 2024/25
- Module Leader(s): Professor Andrew Houlton
- Lecturer: Dr Keith Izod, Dr Simon Doherty, Dr James Dawson
- Owning School: Natural and Environmental Sciences
- Teaching Location: Newcastle City Campus
Semesters
Your programme is made up of credits, the total differs on programme to programme.
Semester 1 Credit Value: | 10 |
Semester 2 Credit Value: | 10 |
ECTS Credits: | 10.0 |
European Credit Transfer System | |
Pre-requisite
Modules you must have done previously to study this module
Pre Requisite Comment
NES2403 - Inorganic Chemistry
Co-Requisite
Modules you need to take at the same time
Co Requisite Comment
An MChem placement in a university abroad or an approved UK industrial company
Aims
To introduce the fundamental principles and reactions of organometallic chemistry; to introduce concepts of homogeneous catalysis; to demonstrate the diverse chemistry of the s- and p-elements; to introduce inorganic aspects of biological systems and metals in biomedicine; to introduce the fundamentals, diversity and applications of chemistry in the solid state
Outline Of Syllabus
The module will be presented in four courses – Organometallic Chemistry; Bio-inorganic Chemistry; Contemporary Main Group Chemistry; Solid-state Chemistry
Organometallic Chemistry
*Topics selected from the following
*Background and introduction
*The 18-Electron rule
*Important ligand types; carbonyl (bonding and binary carbonyls)
*Pi-ligands, hydrides, phosphines
*The synthesis of organometallic compounds
*Organometallic reaction mechanisms 1. Reaction at the metal: ligand substitution, oxidative addition and
reductive elimination
*Organometallic reaction mechanisms 2: Reactions involving the ligand: migratory insertion, reductive
elimination and nucleophilic additions and abstractions
*Transition metal carbene complexes: synthesis, structure and reactivity
*Homogeneous catalysis: an introduction
Bioinorganic Chemistry
*An introduction to bioinorganic chemistry; the essential metals, metal ion overload-deficiency and treatments.
*An introduction to metalloproteins. Protein structure, metal ion binding groups, protein function and role of metal ions.
*Further topics selected from the following
*Myoglobin– protein structure and function, haem group, oxidation and spin states of the metal centre before and after oxygen coordination
*Haemoglobin – protein structure and function, comparison with Mb,
*Metallo-enzymes – details of the structure and function of Zn and Fe-containing systems
*Metal ion binding in DNA. Discovery of metal-containing anti-tumour drugs. mode of action, side effects. Metal-based drugs
Comparative Main Group Chemistry
Topics selected from the following:
*General principles. Complexes of the s-elements: macrocycles and the macrocyclic effect, alkalides and electrides
*Organometallics of the electropositive metals: an introduction to electron-deficient compounds
*More electron-deficient compounds: boranes and carboranes, Zintl ions
*Low oxidation states of the p-block elements (groups 13 and 14)
*E=E bonds (groups 14 and 15); synthesis and reactions. Phosphorus (V) ylides and related compounds
*E=E’ bonds – stability, synthesis and reactions
Sold-state Chemistry
Topics selected from the following:
*Introduction to solid-state chemistry – background, applications, importance and diversity of materials and structures types of solid state, i.e., 0D to 3D, including crystals and molecular solids.
*Structures of solids – crystal structure and chemistry, packing, unit cells and important structures.
*Bonding and electronic structure in solids – types of bonding in solids, band theory, metals/semiconductors/insulators.
*Electrical properties – metallic conductivity, superconductivity + semiconductors.
*Ionic diffusion and conductivity – how ions move in solids, models and types of diffusion, role of ionic conductivity.
*Defects, doping and non-stoichiometry in crystals – points defects and why they form, extended defects, role of doping and nonstoichiometry.
Learning Outcomes
Intended Knowledge Outcomes
At the end of this module, students will:
• understand organometallic synthesis and reaction mechanism
• know about homogenous catalysis using organometallic compounds
• know about the organometallics of groups 1, 2 and 13
• know about the low oxidation state and multiply-bonded compounds of the p-block elements
• understand the chemistry of boranes and related cluster compounds
• understand of basic principles of bioinorganic chemistry
• know about the biological function of transition metal ions
• know about the biological periodic table
• know about a range of metalloproteins
• understand details of the interaction of metal ions and complexes with nucleic acid
• know about metal complexes as drugs
• know understand the mechanism of action of platinum-based anti-cancer drugs
understand and appreciate the background, diversity, applications and importance of materials in the solid state
understand the various structures and types of solid compounds
understand the role of defects and doping in crystalline materials and how these influence properties
know about the various types of bonding and electronic structures in solid compounds
Intended Skill Outcomes
Cognitive or intellectual skills, able to:
• visualize three-dimensional inorganic molecules
• solve problems concerning inorganic bonding, synthesis and mechanism (more advanced than Stage 2)
Key skills, able to:
• plan and organise studies
• undertake self-directed study
Teaching Methods
Teaching Activities
Category | Activity | Number | Length | Student Hours | Comment |
---|---|---|---|---|---|
Placement/Study Abroad | Employer-based learning | 1 | 130:00 | 130:00 | Independent Study - Review ReCap lectures, background reading and practice past exam questions (DL) |
Placement/Study Abroad | Employer-based learning | 32 | 1:00 | 32:00 | Lecture - Recorded by ReCap and displayed on Canvas (DL) |
Placement/Study Abroad | Employer-based learning | 1 | 3:00 | 3:00 | Assessment - completion of end of semester 2 examination (DL) |
Placement/Study Abroad | Employer-based learning | 1 | 35:00 | 35:00 | Assessment - preparation and completion revision for assessment (DL) |
Total | 200:00 |
Teaching Rationale And Relationship
Lecture materials are delivered electronically and are used to impart knowledge/understanding. Student learning is supported by the provision of worksheets.
Reading Lists
Assessment Methods
The format of resits will be determined by the Board of Examiners
Exams
Description | Length | Semester | When Set | Percentage | Comment |
---|---|---|---|---|---|
Written Examination | 180 | 2 | A | 100 | Examination |
Exam Pairings
Module Code | Module Title | Semester | Comment |
---|---|---|---|
Advanced Inorganic Chemistry | 2 | N/A |
Formative Assessments
Formative Assessment is an assessment which develops your skills in being assessed, allows for you to receive feedback, and prepares you for being assessed. However, it does not count to your final mark.
Description | Semester | When Set | Comment |
---|---|---|---|
Digital Examination | 1 | A | Assessment of part module examination |
Assessment Rationale And Relationship
A formative exam will assess the level of knowledge and understanding from topics studied in semester 1. This will allow the module team to review and feedback on any topic which may have been problematic.
The summative written examination will assess the level of knowledge and understanding of the content of the module. The examination will present students with questions from a selection of topics learnt throughout semester 1 and 2 module content.
Timetable
- Timetable Website: www.ncl.ac.uk/timetable/
- NES3407's Timetable
Past Exam Papers
- Exam Papers Online : www.ncl.ac.uk/exam.papers/
- NES3407's past Exam Papers
General Notes
N/A
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