Sepsis

SHORTER - Recruiting

A randomised controlled trial of SHORT duration antibiotic therapy for critically ill patients with sepsis.

• Study stage: Recruiting
• Sponsor: The Newcastle upon Tyne Hospitals NHS Foundation Trust
• Funder:  NIHR HTA
• Therapeutic area: Sepsis
• Type of study: Non-CTIMP

Aim: To determine whether short-duration antibiotic treatment is as good as routine practice, which is usually a longer duration of antibiotics, for critically ill patients with sepsis.

Primary outcome: To determine whether short duration antibiotic therapy is non-inferior to standard of care in terms of mortality and reduces overall antibiotic exposure.

• Population: Adults
• Setting: Critical Care
• Trial Design: RCT
• Planned swample size: 2244

Website:  https://www.shortertrial.com/