Staff Profile

Working as part of the enterprise team of the Science, Agriculture and Engineering (SAgE) faculty my role is to assist research active staff in the Schools of Chemistry and Chemical Engineering in a comprehensive range of enterprise related projects. 

• Explore our technology transfer and licensing opportunities
• Find out more about our spin-out companies

• Articles

  • Miller DC, Reuillon T, Molyneux L, Blackburn T, Cook SJ, Edwards N, Endicott JA, Golding BT, Griffin RJ, Hardcastle I, Harnor SJ, Heptinstall A, Lochhead P, Martin MP, Martin NC, Myers S, Newell DR, Noble RA, Phillips N, Rigoreau L, Thomas H, Tucker JA, Wang L-Z, Waring MJ, Wong A-C, Wedge SR, Noble MEM, Cano C. Parallel Optimization of Potency and Pharmacokinetics Leading to the Discovery of a Pyrrole Carboxamide ERK5 Kinase Domain Inhibitor. Journal of Medicinal Chemistry 2022, 65(9), 6513-6540.
  • Myers SM, Miller DC, Molyneux L, Arasta M, Bawn RH, Blackburn TJ, Cook SJ, Edwards N, Endicott JA, Golding BT, Griffin RJ, Hammonds T, Hardcastle IR, Harnor SJ, Heptinstall AB, Lochhead PA, Martin MP, Martin NC, Newell DR, Owen PJ, Pang LC, Reuillon T, Rigoreau LJM, Thomas HD, Tucker JA, Wang L-Z, Wong A-C, Noble MEM, Wedge SR, Cano C. Identification of a novel orally bioavailable ERK5 inhibitor with selectivity over p38α and BRD4. European Journal of Medicinal Chemistry 2019, 178, 530-543.
  • Blackburn TJ, Thomas EJ. Synthetic approaches to phomactins: Novel oxidation of homoallylic alcohols using tetra-n-propylammonium perruthenate. Tetrahedron 2018, 74(38), 5399-5407.
  • Blackburn T, Kilner M, Thomas E. Synthetic approaches to phomactins: on the stereoselectivity of some [2,3]-Wittig rearrangements. Tetrahedron 2015, 71(39), 7293-7309.
  • Blackburn TJ, Ahmed S, Coxon CR, Liu JF, Lu XH, Golding BT, Griffin RJ, Hutton C, Newell DR, Ojo S, Watson AF, Zaytzev A, Zhao Y, Lunec J, Hardcastle IR. Diaryl- and triaryl-pyrrole derivatives: inhibitors of the MDM2-p53 and MDMX-p53 protein-protein interactions. MedChemComm 2013, 4(9), 1297-1304.
  • Coffey K, Blackburn TJ, Cook S, Golding BT, Griffin RJ, Hardcastle IR, Hewitt L, Huberman K, McNeill HV, Newell DR, Roche C, Ryan-Munden CA, Watson A, Robson CN. Characterisation of a Tip60 specific inhibitor, NU9056, in prostate cancer. PLoS One 2012, 7(10), e45539.
  • Hardcastle IR, Liu J, Valeur E, Watson A, Ahmed SU, Blackburn TJ, Bennaceur K, Clegg W, Drummond C, Endicott JA, Golding BT, Griffin RJ, Gruber J, Haggerty K, Harrington RW, Hutton C, Kemp S, Lu X, McDonnell JM, Newell DR, Noble ME, Payne SL, Revill CH, Riedinger C, Xu Q, Lunec J. Isoindolinone Inhibitors of the Murine Double Minute 2 (MDM2)-p53 Protein-Protein Interaction: Structure-Activity Studies Leading to Improved Potency. Journal of Medicinal Chemistry 2011, 54(5), 1233-1243.
  • Blackburn T, Helliwell M, Kilner M, Lee A, Thomas E. Further studies of an approach to a total synthesis of phomactins. Tetrahedron Letters 2009, 50(26), 3550-3554.
  • Lewis R, Blackaby W, Blackburn T, Jennings A, Pike A, Wilson R, Hallet D, Cook S, Pushpinder F, Marshall G, Reynolds D, Sheppard W, Smith A, Sohal B, Stanley J, Tye S, Wafford K, Atack J. A Pyridazine Series of α2/α3 Subtype Selective GABA_A Agonists for the Treatment of Anxiety. Journal of Medicinal Chemistry 2006, 49(8), 2600-2610.