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Our Equipment

Our facility is equipped with a wide range of instruments.

Mass Spectrometry

We are equipped with:

  • Bruker Rapiflex (MALDI)  
  • Thermo QExactive HF
  • Sciex 6600 QToF (intact protein) 
  • Thermo Exploris  240 (ICMS)
  • Sciex 5600 QToF (metabolomics) 
  • Thermo Fusion Lumos
  • Bruker timsTOF HT   
  • Thermo Exploris 480

Protein Purification

We are equipped with:

  •   AKTA purification system
  •   Sorvall RC6+ and Evolution floor standing centrifuges
  •   Shimadzu UV-1800 spectrophotometer
  •   Purification matrices, Affinity chromatography:
    •   PROBOND
    •   IMAC
  •   Ion exchange chromatography:
    •   DEAE Sephacel, Q Sepharose
    •   SP Sepharose
  •   Size exclusion chromatography:
    •   Sephacryl S300
  •   Hydrophobic interaction chromatography:
    •   Phenyl Sepharose
  • Hydroxyapatite chromatography

Molecular Biophysics

We are equipped with:

  • Beckman ProteomeLab XLA-XLI analytical ultracentrifuge (equipped with absorbance and interference detection)
  • Microcal VC-ITC
  • Microcal VC-DSC
  • Sciex 6600 QToF Mass Spectrometer (intact protein)

We also have access to instruments which complement our expertise in the following techniques:

  • Surface plasmon resonance (Biacore S-200)
  • Small-angle X-ray scattering instruments (Diamond synchrotron)
  • Small angle neutron scattering (RAL)
  • Fourrier-transform infra-red spectroscopy (Perkin Elmer)
  • Circular dichroism spectroscopy