Publications

Tinning H, Taylor A, Wang D, Constantinides B, Sutton R, Oikonomou G, Velazquez MA, Thompson P, Treumann A, O'Connell MJ, Forde N. The role of CAPG in molecular communication between the embryo and the uterine endometrium: Is its function conserved in species with different implantation strategies? FASEB J. 2020 Jul 3. doi: 10.1096/fj.202000882RR. (Epub ahead of print) PMID: 32619075.

Lence E, Maneiro M, Sanz-Gaitero M, van Raaij MJ, Thompson P, Hawkins AR, González-Bello C. Self-Immolation of a Bacterial Dehydratase Enzyme by its Epoxide Product. Chemistry. 2020 Jun 26;26(36):8035-8044. doi: 10.1002/chem.202000759. Epub 2020 Jun 8. PMID: 32259333

Verheul, J. Yau H. LLodge A, Liu X., Solovyova AS, Typas A, Banzhaf M., Vollmer W, den Blaauwen T.^.Midcell localization of PBP4 of  Escherichia coli is essential for the timing of the divisome (2020) submitted

Palmowski, P., Watson, R., Europe-Finner, G.N., Karolczak-Bayatti, M., Porter, A.J., Treumann, A., Taggart. M.J., The Generation of a Comprehensive Spectral Library for the Analysis of the Guinea Pig Proteome by SWATH-MS, Proteomics; 19(15) 1900156

Meyer, S.K., Dunn, M., Vidler, D,S., Porter A.J., Blain, P.G., Jowsey, P.A., 2019. Phosphorylation of MCPH1 Isoforms during Mitosis Followed by Isoform-Specific Degradation by APC/C-CDH1. FASEB J.;33(2):2796-2808

MakarovAA, Zou J, Houston DR, Spanos C, Solovyova AS, Cardenal-Perrata C. RappsilberJ, SchirmerEC. Lamin A molecular compression and sliding as mechanisms behind nucleoskeleton elasticity. Nature Communications 2019, 10:3056

Huang Y, Soliakov A, Le Brun AP, Macdonald C, Johnson CL, Solovyova AS, Waller H, Moore GR,Lakey JH. Helix N-Cap Residues Drive the Acid Unfolding That Is Essential in the Action of the Toxin Colicin A Biochemistry 2019 58(48):4882-4892.

Baslé A, Hewitt L, Koh A, Lamb HK, Thompson P, Burgess JG, Hall MJ, Hawkins AR, Murray H, Lewis RJ. Crystal structure of NucB, a biofilm-degrading endonuclease. Nucleic Acids Res. 2018 Jan 9;46(1):473-484. doi: 10.1093/nar/gkx1170 PMID: 29165717.

Robson T., Shah D.S.H., Solovyova AS., Lakey J.H. Modular Protein Engineering Approach to the Functionalization of Gold Nanoparticles for Use in Clinical Diagnostics ACS Appl Nano Matter. 2018 Jul 27;1(7):3590-3599.

Linthwaite, V. L., Janus, J. M., Brown, A. P., Wong-Pascua, D., O'Donoghue, A. C., Porter, A.J., Treumann, A., Hodgson, D. R. W., Cann, M. J. 2018. The identification of carbon dioxide mediated protein post-translational modifications. Nature Communications 9, Article number: 3092

Hallam D., Hilgen G., Dorgau B., Zhu L., Yu M., Bojic S., Hewitt P., Schmitt M., Uteng M., Kustermann S., Steel D., Nicholds M., Thomas R., Treumann A., Porter A.J., Sernagor E., Armstrong L., Lako M.,. 2018 Human-Induced Pluripotent Stem Cells Generate Light Responsive Retinal Organoids with Variable and Nutrient-Dependent Efficiency. Stem Cells;36(10):1535-1551.

Austin, C.A., Lee, K.C., Swan, R.L., Khazeem, M.M., Manville, C.M., Cridland, P., Treumann, A., Porter, A.J., Morris, N.J., Cowell, I.G., 2018. TOP2B: The First Thirty Years. J Mol Sci. 14;19(9)

Dams, M., Dores-Sousa, J., Lamers, RJ., Treumann, A., Eeltink, S.,High-Resolution Nano-Liquid Chromatography with Tandem Mass Spectrometric Detection for the Bottom-Up Analysis of Complex Proteomic Samples Chromatographia 2018 10.1007/s10337-018-3647-

Treumann A, Palmowski P, Tong WC, Taggart J, Morrice N, Nicholas Europe-Finner G, Taggart MJ. Depletion of Myofibril-Associated Proteins Using Selective Protein Extraction as a Tool in Cardiac Proteomics. Methods in Molecular Biology (Clifton, N.J.). PMID 28975594 DOI: 10.1007/7651_2017_73

Johnson CL, Solovyova AS, Hecht O, Macdonald C, Waller H, Grossmann JG, Moore GR, Lakey JH The Two-State Prehensile Tail of the Antibacterial Toxin Colicin N. Biophys J. 2017 Oct 17;113(8):1673-1684

Peón A, Robles A, Blanco B, Convertino M, Thompson P, Hawkins AR, Caflisch A, González-Bello C. Reducing the Flexibility of Type II Dehydroquinase for Inhibition: A Fragment-Based Approach and Molecular Dynamics Study. ChemMedChem. 2017 Sep 21;12(18):1512-1524. doi: 10.1002/cmdc.201700396. PMID: 28791799

Wilkinson DJ, Wang H, Habgood A, Lamb HK, Thompson P, Hawkins AR, Désilets A, Leduc R, Steinmetzer T, Hammami M, Lee MS, Craik CS, Watson S, Lin H, Milner JM, Rowan AD. Matriptase Induction of Metalloproteinase-Dependent Aggrecanolysis In Vitro and In Vivo: Promotion of Osteoarthritic Cartilage Damage by Multiple Mechanisms. Arthritis Rheumatol. 2017 Aug;69(8):1601-1611. doi: 10.1002/art.40133. Epub 2017 Jul 5.PMID: 28464560

Prado V, Lence E, Thompson P, Hawkins AR, González-Bello C. Freezing the Dynamic Gap for Selectivity: Motion-Based Design of Inhibitors of the Shikimate Kinase Enzyme.Chemistry. 2016 Dec 12;22(50):17988-18000. doi: 10.1002/chem.201602923. Epub 2016 Oct 4 PMID: 27699905

Prado V, Lence E, Maneiro M, Vázquez-Ucha JC, Beceiro A, Thompson P, Hawkins AR, González-Bello C. Targeting the Motion of Shikimate Kinase: Development of Competitive Inhibitors that Stabilize an Inactive Open Conformation of the Enzyme J Med Chem. 2016 Jun 9;59(11):5471-87. doi: 10.1021/acs.jmedchem.6b00483. Epub 2016 May 18.PMID: 27191386

Rogowski A, Briggs JA, Mortimer JC, Tryfona T, Terrapon N, Lowe EC, Baslé A, Morland C, Day AM, Zheng H, Rogers TE, Thompson P, Hawkins AR, Yadav MP, Henrissat B, Martens EC, Dupree P, Gilbert HJ, Bolam DN. Corrigendum: Glycan complexity dictates microbial resource allocation in the large intestine.Nat Commun. 2016 Feb 5;7:10705. doi: 10.1038/ncomms10705. PMID: 26848059

Prado V, Lence E, Vallejo JA, Beceiro A, Thompson P, Hawkins AR, González-Bello C. Study of the Phosphoryl-Transfer Mechanism of Shikimate Kinase by NMR Spectroscopy.Chemistry. 2016 Feb 18;22(8):2758-68. doi: 10.1002/chem.201504438. PMID: 26797764

Arunmanee W, Pathania M, Solovyova AS, Le Brun AP, Ridley H, Baslé A, van den Berg B, Lakey JH. Gram-negative trimeric porins have specific LPS binding sites that are essential for porin biogenesis. PNAS 2016, 113(34), E5034-E5043

Hjerpe R, Bett J, Keuss MJ, Solovyova A, McWilliams TG, Johnson C, Sahu I, Varghese J, Wood N, Wightman M, Osbourne G, Bates GP, Glickman MH, Trost M, Knebel A, Marchesi F, Kurz T. UBQLN2 connects the proteasome with the HSP70 system to promote autophagy-independent protein aggregate clearance. Cell, 2016;166(4):935-949

R.M.H. Zhao, R. Ghirlando, …….A.S. Solovyova et al. A Multilaboratory Comparison of Calibration Accuracy and the Performance of External References in Analytical Ultracentrifugation PLoS ONE 2015 10(5): e0126420.

Amini AA, Solovyova AS, Sadeghian H, Blackbourn DJ, Rezaee SA Structural properties of viral orthologue of cellular CD200 protein KSHV vOX2. Virology 2015; 474(1):94-104

González-Bello C, Tizón L, Lence E, Otero JM, van Raaij MJ, Martinez-Guitian M, Beceiro A, Thompson P, Hawkins AR. Chemical Modification of a Dehydratase Enzyme Involved in Bacterial Virulence by an Ammonium Derivative: Evidence of its Active Site Covalent Adduct. J Am Chem Soc. 2015 Jul 29;137(29):9333-43. doi: 10.1021/jacs.5b04080 PMID: 26148116

Rogowski A, Briggs JA, Mortimer JC, Tryfona T, Terrapon N, Lowe EC, Baslé A, Morland C, Day AM, Zheng H, Rogers TE, Thompson P, Hawkins AR, Yadav MP, Henrissat B, Martens EC, Dupree P, Gilbert HJ, Bolam DN. Glycan complexity dictates microbial resource allocation in the large intestine.Nat Commun. 2015 Jun 26;6:7481. doi: 10.1038/ncomms8481.PMID: 26112186.

R.M. Cleverley, J.R. Barrett, A. Basle, N.K. Bui, L. Hewitt, A.S. Solovyova, Z. Xu, R.A. Daniel, N.E. Dixon, E.J. Harry, A.J. Oakley, W. Vollmer, R.J. Lewis Structure and function of a spectrin-like regulator of bacterial cytokinesis Nature Communications 2014 18 (5):5421

A.J.F. Egan, N.L. Jean, A. Koumoutsi, C.M. Bougault, J. Biboy, J. Sassine,A.S. Solovyova, E. Breukink, N. Typas, W. Vollmer, J.-P. Simorre The outer-membrane lipoprotein LpoB spans the periplasm to stimulate the peptidoglycan synthase PBP1B, PNAS (2014) 111(22):8197

A. Rogowski, A. Baslé, C.S. Farinas, A.S. Solovyova, J.C. Mortimer, P. Dupree, H.J. Gilbert,D.N. Bolam  Evidence that GH115 -glucuronidase activity is dependent on conformational flexibility, J Biol Chem. (2014) 289(1):53

Collins DC, Cocchiglia S, Tibbitts P, Solon G, Bane FT, McBryan J, Treumann A, Eustace A, Hennessy B, Hill AD, Young LS. Growth factor receptor/steroid receptor cross talk in trastuzumab-treated breast cancer. Oncogene 2014, 1-6.

Miwa S, Jow H, Baty K, Johnson A, Czapiewski R, Saretzki G, Treumann A, von Zglinicki T. Low abundance of the matrix arm of complex I in mitochondria predicts longevity in mice. Nature Communications 2014, 5, 3837.

Radziwon-Balicka A, Santos-Martinez MJ, Corbalan JJ, O'Sullivan S, Treumann A, Gilmer JF, Radomski MW, Medina C. Mechanisms of platelet-stimulated colon cancer invasion: role of clusterin and thrombospondin 1 in regulation of the P38MAPK-MMP-9 pathway. Carcinogenesis 2014, 35(2), 324-332.