Staff Profile
Dr Alexandra Solovyova
Experimental Scientific Officer
- Email: alexandra.solovyova@ncl.ac.uk
- Telephone: +44 (0) 191 208 8785
- Fax: +44 (0) 191 208 7424
- Address: Institute for Cell and Molecular Biosciences
The Medical School
University of Newcastle
Catherine Cookson Building
Framlington Place
Newcastle
NE2 4HH
Publications
- Johnson CL, Solovyova AS, Hecht O, Macdonald C, Waller H, Grossmann JG, Moore GR, Lakey JH. The Two-State Prehensile Tail of the Antibacterial Toxin Colicin N. Biophysical Journal 2017, 113(8), 1673-1684.
- Arunmanee W, Pathania M, Solovyova AS, Le Brun AP, Ridley H, Baslé A, van den Berg B, Lakey JH. Gram-negative trimeric porins have specific LPS binding sites that are essential for porin biogenesis. Proceedings of the National Academy of Sciences of the USA 2016, 113(34), E5034-E5043.
- Hjerpe R, Bett J, Keuss MJ, Solovyova A, McWilliams TG, Johnson C, Sahu I, Varghese J, Wood N, Wightman M, Osbourne G, Bates GP, Glickman MH, Trost M, Knebel A, Marchesi F, Kurz T. UBQLN2 Mediates Autophagy-Independent Protein Aggregate Clearance by the Proteasome. Cell 2016, 166(4), 935–949.
- Hjerpe R, Bett JS, Keuss MJ, Solovyova A, McWilliams TG, Johnson C, Sahu I, Varghese J, Wood N, Wightman M, Osborne G, Bates GP, Glickman MH, Trost M, Knebel A, Marchesi F, Kurz T. UBQLN2 Mediates Autophagy-Independent Protein Aggregate Clearance by the Proteasome. Cell 2016, 166(4), 935-949.
- Zhao HY, Ghirlando R, Alfonso C, Arisaka F, Attali I, Bain DL, Bakhtina MM, Becker DF, Bedwell GJ, Bekdemir A, Besong TMD, Birck C, Brautigam CA, Brennerman W, Byron O, Bzowska A, Chaires JB, Chaton CT, Colfen H, Connaghan KD, Crowley KA, Curth U, Daviter T, Dean WL, Diez AI, Ebel C, Eckert DM, Eisele LE, Eisenstein E, England P, Escalante C, Fagan JA, Fairman R, Finn RM, Fischle W, de la Torre JG, Gor J, Gustafsson H, Hall D, Harding SE, Cifre JGH, Herr AB, Howell EE, Isaac RS, Jao SC, Jose D, Kim SJ, Kokona B, Kornblatt JA, Kosek D, Krayukhina E, Krzizike D, Kusznir EA, Kwon H, Larson A, Laue TM, Le Roy A, Leech AP, Lilie H, Luger K, Luque-Ortega JR, Ma J, May CA, Maynard EL, Modrak-Wojcik A, Mok YF, Mucke N, Nagel-Steger L, Narlikar GJ, Noda M, Nourse A, Obsil T, Park CK, Park JK, Pawelek PD, Perdue EE, Perkins SJ, Perugini MA, Peterson CL, Peverelli MG, Piszczek G, Prag G, Prevelige PE, Raynal BDE, Rezabkova L, Richter K, Ringel AE, Rosenberg R, Rowe AJ, Rufer AC, Scott DJ, Seravalli JG, Solovyova AS, Song RJ, Staunton D, Stoddard C, Stott K, Strauss HM, Streicher WW, Sumida JP, Swygert SG, Szczepanowski RH, Tessmer I, Toth RT, Tripathy A, Uchiyama S, Uebel SFW, Unzai S, Gruber AV, von Hippel PH, Wandrey C, Wang SH, Weitzel SE, Wielgus-Kutrowska B, Wolberger C, Wolff M, Wright E, Wu YS, Wubben JM, Schuck P. A Multilaboratory Comparison of Calibration Accuracy and the Performance of External References in Analytical Ultracentrifugation. PLoS One 2015, 10(5), e0126420.
- Ali Amini A, Solovyova AS, Sadeghian H, Blackbourn DJ, Rezaee SAR. Structural properties of a viral orthologue of cellular CD200 protein: KSHV vOX2. Virology 2015, 474, 94-104.
- Rogowski A, Basle A, Farinas CS, Solovyova A, Mortimer JC, Dupree P, Gilbert HJ, Bolam DN. Evidence That GH115 alpha-Glucuronidase Activity, Which Is Required to Degrade Plant Biomass, Is Dependent on Conformational Flexibility. Journal of Biological Chemistry 2014, 289(1), 53-64.
- Egan AJF, Jean NL, Koumoutsi A, Bougault CM, Biboy J, Sassine J, Solovyova AS, Breukink E, Typas A, Vollmer W, Simorre JP. Outer-membrane lipoprotein LpoB spans the periplasm to stimulate the peptidoglycan synthase PBP1B. Proceedings of the National Academy of Sciences of the United States of America 2014, 111(22), 8197-8202.
- Cleverley RM, Barrett JR, Baslé A, Bui NK, Hewitt L, Solovyova A, Xu Z-Q, Daniel RA, Dixon NE, Harry EJ, Oakley AJ, Vollmer W, Lewis RJ. Structure and function of a spectrin-like regulator of bacterial cytokinesis. Nature Communications 2014, 5, 5421.
- Arunmanee W, Solovyova A, Johnson CL, Heenan RK, Lakey JH. Understanding Colicin N Import into Gram Negative Bacterial Cells using Small Angle Neutron Scattering. In: 58th Annual Meeting of the Biophysical-Society. 2014, San Francisco, CA: Cell Press.
- Newman JA, Hewitt L, Rodrigues C, Solovyova AS, Harwood CR, Lewis RJ. Dissection of the network of interactions that links RNA processing with glycolysis in the Bacillus subtilis degradosome. Journal of Molecular Biology 2012, 416(1), 121-136.
- Cuskin F, Flint JE, Gloster TM, Morland C, Basle A, Henrissat B, Coutinho PM, Strazzulli A, Solovyova AS, Davies GJ, Gilbert HJ. How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity. Proceedings of the National Academy of Sciences 2012, 109(51), 20889-20894.
- Clifton LA, Johnson CL, Solovyova AS, Callow P, Weiss KL, Ridley H, Le Brun AP, Kinane CJ, Webster JRP, Holt SA, Lakey JH. Low Resolution Structure and Dynamics of a Colicin-Receptor Complex Determined by Neutron Scattering. Journal of Biological Chemistry 2012, 287(1), 337-346.
- Cuskin F, Solovyova AS, Lewis RJ, Race PR. Crystallization and preliminary X-ray analysis of the bacillaene synthase trans-acting acyltransferase PksC. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications Online 2011, 67(4), 464-466.
- Johnson CL, Clifton LA, Solovyova A, Callow P, Weiss KL, Ridley H, Le Brun AP, Holt SA, Lakey JH. Small-Angle Neutron Scattering Reveals Colicin N Inserts into Clefts on the Outside of the OmpF Trimer. In: 55th Annual Meeting of the Biophysical Society. 2011, Baltimore, MD: Cell Press.
- Newman JA, Hewitt L, Rodrigues C, Solovyova A, Harwood CR, Lewis RJ. Unusual, dual endo- and exonuclease activity in the degradosome explained by crystal structure analysis of RNaseJ1. Structure 2011, 19(9), 1241-1251.
- Solovyova A. Preface: 17th International symposium on analytical ultracentrifugation and hydrodynamics. European Biophysics Journal 2010, 39(3), 345-346.
- Heinze RJ, Giron-Monzon L, Solovyova A, Elliot SL, Geisler S, Cupples CG, Connolly BA, Friedhoff P. Physical and functional interactions between Escherichia coli MutL and the Vsr repair endonuclease. Nucleic Acids Research 2009, 37(13), 4453-4463.
- Race PR, Solovyova AS, Banfield MJ. Conformation of the EPEC Tir protein in solution: Investigating the impact of serine phosphorylation at positions 434/463. Biophysical Journal 2007, 93(2), 586-596.