Staff Profile
Dr Jon Sellars
Lecturer in Medicinal Chemistry
- Personal Website: http://sellarsgroupnewcastle.co.uk
- Address: School of Pharmacy
Faculty of Medical Sciences
King George VI Building
Newcastle-upon-Tyne
NE1 7RU
Dr Jon Sellars is a Lecturer in Medicinal chemistry at the School of Pharmacy and the Institute of Cellular Medicine at Newcastle University.
He gained a PhD with Prof. Patrick Steel at Durham University investigating the utility of silacyclohex-4-enes in organic synthesis. Subsequent employment at Sanofi-Aventis in Alwnick working on radio labelling active pharmaceutical ingredients was followed by a return to Durham University, to undertake a post doctoral position with Prof. Patrick Steel and Prof Robert Edwards investigating multiple herbicide resistance in black grass (supported by Syngenta).
In 2010, Jon was awarded an EPSRC Life Sciences Interface Fellowship to develop novel proteomic probes to study cytochrome P450's. After completion, Jon undertook a teaching fellowship at Durham University where in 2015 was appointed to a lectureship in medicinal chemistry at the School of Pharmacy. In August 2017 the School was transferred to Newcastle University resulting in the creation of the School of Pharmacy.
Areas of expertise
- Organic Synthesis
- Proteomics
- Chemical Biology
Google Scholar: Click Here
-
Articles
- Potter ZE, Hill MT, Sellars JD, Waddell PG. A New Polymorph of tert-Butyl (2-Aminophenyl)Carbamate. Journal of Chemical Crystallography 2024, epub ahead of print.
- Brown AK, Aljohani AKB, Alsalem FMA, Broadhead JL, Gill JH, Lu Y, Sellars JD. Identification of Substituted Amino Acid Hydrazides as Novel Anti-Tubercular Agents, Using a Scaffold Hopping Approach. Molecules 2020, 25(10), 2387-2411.
- Brown AK, Aljohani AKB, Gill JH, Steel PG, Sellars JD. Identification of novel benzoxa-[2,1,3]-diazole substituted amino acid hydrazides as potential anti-tubercular agents. Molecules 2019, 24(4), 811.
- Smith EL, Ridout J, Sellars JD, Probert MR. A structural exploration of anisole accessed through extreme conditions crystallisation. CrystEngComm 2019, 21(30), 4422-4426.
- Brazier-Hicks M, Knight KM, Sellars JD, Steel PG, Edwards R. Testing a chemical series inspired by plant stress oxylipin signalling agents for herbicide safening activity. Pest Management Science 2018, 74(4), 828-836.
- Sellars JD, Skipsey M, Sadr-ul-Shaheed, Gravell S, Abumansour H, Kashtl G, Irfan J, Khot M, Pors K, Patterson LH, Sutton CW. Rational Development of Novel Activity Probes for the Analysis of Human Cytochromes P450. ChemMedChem 2016, 11(11), 1122-1128.
- Czyzewski M, Sellars JD, Guliashvili T, Tibbelin J, Johnstone L, Bower J, Box M, Davies RDM, Ottosson H, Steel PG. The first intramolecular silene Diels-Alder reactions. Chemical Communications 2014, 50(22), 2919-2921.