Staff Profile

CHY1402 - Data Handling in Chemistry and Medicinal Chemistry

CHY2401 - Structural Chemistry  (Module Leader)

CHY8833 - Structural and Analytical Chemistry (Module Leader)

• Articles

  • Campbell ADG, Roper NJ, Waddell PG, Wills C, Dixon CM, Denton RM, Ermanis K, Armstrong RJ. Synthesis, Structure and Stereodynamics of Atropisomeric N‑Chloroamides. Chemical Communications 2024, 60(28), 3818-3821.
  • Doherty S, Knight JG, Alharbi AA, Will C, Dixon C, Cheng C, Russo Abegão F, Chamberlain TW, Yan H, Griffiths A, Bourne RA, Collins SM, Wu KJ, Alshaikh H. Selective Partial Reduction of Nitroarenes to the Hydrazoarene Catalyzed by Amine-Modified Ordered Mesoporous Silica Immobilized Ionic Liquid (OMSIIL) Stabilised RuNPs. ChemCatChem 2024, 16(13), e202400013.
  • Davison N, Hemingway JM, Wills C, Stolar T, Waddell PG, Dixon CM, Barron L, Dawson JA, Lu E. Mechanochemical Synthesis of a Sodium Anion Complex [Na+(2,2,2-cryptand)Na-] and Studies of Its Reactivity: Two-Electron and One-Electron Reductions. Inorganic Chemistry 2024, 63(32), 15247–15258.
  • Purvis G, Siller L, Crosskey A, Vincent J, Wills C, Sheriff J, Xavier C, Telling J. Generation of long-chain fatty acids by hydrogen-driven bicarbonate reduction in ancient alkaline hydrothermal vents. Communications Earth & Environment 2024, 5, 30.
  • Giron-Hernandez J, Tombe A, Chemban Koyilot M, Salas-Calderon KT, Charlton A, Wills C, Gentile P. From cocoa waste to sustainable bioink: valorising pectin for circular economy-driven tissue engineering. European Polymer Journal 2024, 210, 112967.
  • Alharbi AA, Wills C, Dixon C, Chamberlain T, Arca E, Griffiths A, Collins S, Wu K, Yan H, Bourne R, Knight J, Doherty S. Efficient Hydrogen Evolution from Dimethylamine Borane, Ammonia Borane and Sodium Borohydride Catalyzed by Ruthenium and Platinum Nanoparticles Stabilized by an Amine Modified Polymer Immobilized Ionic Liquid: A Comparative Study. Catalysis Letters 2024, 154, 5450–5471.
  • Davison N, McMullin CL, Zhang L, Hu S-X, Waddell PG, Wills C, Dixon C, Lu E. Li vs Na: Divergent Reaction Patterns between Organolithium and Organosodium Complexes and Ligand-Catalyzed Ketone/Aldehyde Methylenation. Journal of the American Chemical Society 2023, 145(11), 6562–6576.
  • Paterson R, Alharbi HY, Wills C, Chamberlain TW, Bourne RA, Griffiths A, Collins SM, Wu K, Simmons MD, Menzel R, Massey AF, Knight JG, Doherty S. Highly efficient and selective partial reduction of nitroarenes to N-arylhydroxylamines catalysed by phosphine oxide-decorated polymer immobilized ionic liquid stabilized ruthenium nanoparticles. Journal of Catalysis 2023, 417, 74-88.
  • Giron-Hernandez J, Pazmino M, Barrios-Rodriguez YF, Turo CT, Wills C, Cucinotta F, Benlloch-Tinoco M, Gentile P. Exploring the effect of utilising organic acid solutions in ultrasound-assisted extraction of pectin from apple pomace, and its potential for biomedical purposes. Heliyon 2023, 9(7), e17736.
  • Singla P, Parokie G, Garg S, Kaur S, Kaur I, Crapnell RD, Banks C, Rinner U, Wills C, Peeters M. Enhancing encapsulation of hydrophobic phyto-drugs naringenin and baicalein in polymeric nano-mics. Journal of Drug Delivery Science and Technology 2023, 83, 104403.
  • Doherty S, Knight JG, Alharbi AA, Wills C, Chamberlain TW, Bourne RA, Griffiths A, Collins SM, Wu K, Mueller P. Amino-Modified Polymer Immobilized Ionic Liquid Stabilized Ruthenium Nanoparticles: Efficient and Selective Catalysts for the Partial and Complete Reduction of Quinolines. ChemCatChem 2023, 15(11), e202300418.
  • Paterson R, Fahy LE, Arca E, Dixon C, Wills CY, Yan H, Griffiths A, Collins SM, Wu K, Bourne RA, Chamberlain TW, Knight JG, Doherty S. Amine-modified polyionic liquid supports enhance the efficacy of PdNPs for the catalytic hydrogenation of CO₂ to formate. Chemical Communications 2023, 59, 13470-13473.
  • Shiels D, Pascual-Borràs M, Waddell PG, Wills C, Poblet JM, Errington RJ. A thirty-year old mystery solved: identification of a new heptatungstate from non-aqueous solutions. Chemical Communications 2023, 59(51), 7919-7922.
  • Davison N, Zhou K, Waddell PG, Wills C, Dixon C, Hu S-X, Lu E. Versatile Coordination Modes of Multidentate Neutral Amine Ligands with Group 1 Metal Cations. Inorganic Chemistry 2022, 61(8), 3674–3682.
  • Izod K, Liu M, Evans P, Wills C, Dixon CM, Waddell PG, Probert MR. Spontaneous Decomposition of an Extraordinarily Twisted and Trans-Bent Fully-Phosphanyl-Substituted Digermene to an Unusual Ge^I Cluster. Angewandte Chemie - International Edition 2022, 61(39), e202208851.
  • Kepplinger B, Wen X, Tyler AR, Kim BY, Brown J, Banks P, Dashti Y, Mackenzie ES, Wills C, Kawai Y, Waldron KJ, Allenby NEE, Wu LJ, Hall MJ, Errington J. Mirubactin C rescues the lethal effect of cell wall biosynthesis mutations in Bacillus subtilis. Frontiers in Microbiology 2022, 13, 1004737.
  • Paterson R, Alharbi AA, Wills C, Dixon C, Siller L, Chamberlain TW, Griffiths A, Collins SM, Wu KJ, Simmons MD, Bourne RA, Lovelock KRJ, Seymour J, Knight JG, Doherty S. Heteroatom Modified Polymer Immobilized Ionic Liquid Stabilized Ruthenium Nanoparticles: Efficient Catalysts for the Hydrolytic Evolution of Hydrogen from Sodium Borohydride. Molecular Catalysis 2022, 528, 112476.
  • Davison N, Quirk JA, Wills C, Dixon C, Waddell PG, Dawson JA, Lu E. Elucidating Solution-State Coordination Modes of Multidentate Neutral Amine Ligands with Group-1 Metal Cations: Variable-Temperature NMR Studies. Inorganic Chemistry 2022, 61(38), 15204-15212.
  • Doherty S, Knight JG, Alharbi HY, Paterson R, Wills C, Dixon C, Siller L, Chamberlain TW, Griffiths A, Collins SM, Wu KJ, Simmonds SD, Bourne RA, Lovelock KRJ, Seymour J. Efficient Hydrolytic Hydrogen Evolution from Sodium Borohydride Catalyzed by Polymer Immobilized Ionic Liquid-Stabilized Platinum Nanoparticles. ChemCatChem 2022, 14(4), e202101752.
  • Kepplinger B, Mardiana L, Cowell J, Morton-Laing S, Dashti Y, Wills C, Marrs ECL, Perry JD, Gray J, Goodfellow M, Errington J, Probert MR, Clegg W, Bogaerts J, Herrebout W, Allenby N, Hall MJ. Discovery, Isolation, Heterologous Expression and Mode-of Action Studies of the Antibiotic Polyketide Tatiomicin from Amycolatopsis sp. DEM30355. Scientific Reports 2022, 12, 15579.
  • Davison N, Waddell PG, Dixon C, Wills C, Penfold TJ, Lu E. A monomeric (trimethylsilyl) methyl lithium complex: synthesis, structure, decomposition and preliminary reactivity studies. Dalton Transactions 2022, 51(28), 10707-10713.
  • Abualnaja M, Cowell J, Jolliffe JD, Wills C, Waddell PG, Clegg W, Hall MJ. Diastereoselective Rearomative Etherifications and Aminations of 2,3,9,9a-Tetrahydro-1H-carbazoles. Tetrahedron 2021, 89, 132144.
  • Doherty S, Knight JG, Alshaikh H, Wilson J, Waddell PG, Wills C, Dixon CM. Arene-Immobilized Ru(II)/TsDPEN Complexes: Synthesis and Applications to the Asymmetric Transfer Hydrogenation of Ketones. European Journal of Inorganic Chemistry 2021, 2021(3), 226-235.
  • Woodford OJ, Ziessel R, Harriman A, Wills C, Alsimaree AA, Knight JG. Optical spectroscopic properties recorded for simple BOPHY dyes in condensed media: The mirror-symmetry factor. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 2019, 208, 57-64.
  • Ndeh D, Munoz JM, Cartmell A, Bulmer D, Wills C, Henrissat B, Gray J. The human gut microbe Bacteroides thetaiotaomicron encodes the founding member of a novel glycosaminoglycan-degrading polysaccharide lyase family PL29. Journal of Biological Chemistry 2018, 293(46), 17906-17916.
  • Mosaei H, Molodtsov V, Kepplinger B, Harbottle J, Moon C, Jeeves R, Ceccaroni L, Shin Y, Morton-Laing S, Marrs ECL, Wills C, Clegg W, Yuzenkova J, Perry JD, Bacon J, Errington J, Allenby NEE, Hall MJ, Murakami KS, Zenkin N. Mode of Action of Kanglemycin A, an Ansamycin Natural Product that Is Active against Rifampicin Resistant Mycobacterium tuberculosis. Molecular Cell 2018, 72(2), 263-274.
  • Probert PM, Leitch AC, Dunn MP, Meyer SK, Palmer JM, Abdelghany TM, Lakey AF, Cooke MP, Talbot H, Wills C, McFarlane W, Blake LI, Rosenmai AK, Oskarsson A, Figueiredo R, Wilson C, Kass GE, Jones DE, Blain PG, Wright MC. Identification of a xenobiotic as a potential environmental trigger in primary biliary cholangitis. Journal of Hepatology 2018, 69(5), 1123-1135.
  • Friedl J, Holland-Cunz MV, Cording F, Pfanschilling FL, Wills C, McFarlane W, Schricker B, Fleck R, Wolfschmidt H, Stimming U. Asymmetric polyoxometalate electrolytes for advanced redox flow batteries. Energy and Environmental Science 2018, 11(10), 3010-3018.
  • Tyler A, Mosaei H, Morton S, Waddell PG, Wills C, McFarlane W, Gray J, Goodfellow M, Errington J, Allenby N, Zenkin N, Hall MJ. Structural Reassignment and Absolute Stereochemistry of Madurastatin C1 (MBJ-0034) and the Related Aziridine Siderophores: Madurastatins A1, B1 and MBJ-0035. Journal of Natural Products 2017, 80(5), 1558-1562.
  • Baksh A, Kepplinger B, Isah H, Probert MR, Clegg W, Wills C, Goodfellow M, Errington J, Allenby N, Hall MJ. Production of 17-O-demethyl-geldanamycin, a cytotoxic ansamycin polyketide, by Streptomyces hygroscopicus DEM20745. Natural Product Research 2017, 31(16), 1895-1900.
  • Doherty S, Knight JG, Perry DO, Ward NAB, Bittner DM, McFarlane W, Wills C, Probert MR. Triaryl-Like MONO-, BIS- and TRISKITPHOS Phosphines: Synthesis, Solution NMR Studies and a Comparison in Gold-Catalysed Carbon-Heteroatom Bond Forming 5-Exo-Dig and 6-Endo-Dig Cyclizations. Organometallics 2016, 35(9), 1265-1278.
  • Fleming JT, Wills C, Waddell PG, Harrington RW, Higham LJ. A comparison of MOP-phosphonite ligands and their applications in Rh(I)- and Pd(II)-catalysed asymmetric transformations. Dalton Transactions 2016, 45(39), 15660-15670.
  • Izod K, Wills C, El-Hamruni S, Harrington RW, Waddell PG, Probert MR. Structural Diversity in Alkaline Earth Metal Complexes of a Phosphine-Borane-Stabilized 1,3-Dicarbanion. Organometallics 2015, 34(11), 2406-2414.
  • Izod K, Wills C, Probert MR, Harrington RW. Synthesis and structure of an acyclic dialkylstannylene. Main Group Metal Chemistry 2014, 37(5-6), 113-117.
  • Klonowski P, Goloboy JC, Uribe-Romo FJ, Sun FR, Zhu LY, Gandara F, Wills C, Errington RJ, Yaghi OM, Klemperer WG. Synthesis and Characterization of the Platinum-Substituted Keggin Anion α-H₂SiPtW₁₁O₄₀^4-. Inorganic Chemistry 2014, 53(24), 13239-13246.
  • Izod K, Wills C, Anderson E, Harrington RW, Probert MR. Insights into the stability and structures of phosphine-boranes and their α-metalated derivatives. Organometallics 2014, 33(19), 5283-5294.
  • Nartop D, Clegg W, Harrington RW, Henderson RA, Wills CY. Binding multidentate ligands to Ni²⁺: kinetic identification of preferential binding sites. Dalton Transactions 2014, 43(8), 3372-3382.
  • Lerrick RI, Winstanley TPL, Haggerty K, Wills C, Clegg W, Harrington RW, Bultinck P, Herrebout W, Benniston AC, Hall MJ. Axially Chiral BODIPYs. Chemical Communications 2014, 50(36), 4714-4716.
  • Izod K, Wills C, Harrington RW, Clegg W. Synthesis and structural characterisation of an unusual phosphine-borane-substituted organoplumbate. Journal of Organometallic Chemistry 2013, 725, 11-14.
  • Doherty S, Knight JG, Ward NAB, Bittner DM, Wills C, McFarlane W, Clegg W, Harrington RW. Electron-Rich Trialkyl-Type Dihydro-KITPHOS Monophosphines: Efficient Ligands for Palladium-Catalyzed Suzuki–Miyaura Cross-Coupling. Comparison with Their Biaryl-Like KITPHOS Monophosphine Counterparts. Organometallics 2013, 32(6), 1773-1788.
  • Bakri R, Booth A, Harle G, Middleton PS, Wills C, Clegg W, Harrington RW, Errington RJ. Rational addition of capping groups to the phosphomolybdate Keggin anion [PMo₁₂O₄₀]^3– by mild, non-aqueous reductive aggregation. Chemical Communications 2012, 48(22), 2779-2781.
  • Benniston AC, Winstanley TPL, Lemmetyinen H, Tkachenko NV, Harrington RW, Wills C. Large Stokes Shift Fluorescent Dyes Based on a Highly Substituted Terephthalic Acid Core. Organic Letters 2012, 14(6), 1374-1377.
  • Kandasamy B, Wills C, McFarlane W, Clegg W, Harrington RW, Rodriguez-Fortea A, Poblet JM, Bruce PG, Errington RJ. An Alkoxido-Tin-Substituted Polyoxometalate [(MeO)SnW5O18](3-): The First Member of a New Family of Reactive {SnW5} Lindqvist-Type Anions. Chemistry: A European Journal 2012, 18(1), 59-62.
  • Izod K, Wills C, Clegg W, Harrington RW. Synthesis, Structure, and Solution Behavior of a Phosphine-Borane-Stabilized 1,3-Dicarbanion. Organometallics 2010, 29(21), 4774-4777.
  • Wills C, Izod K, Clegg W, Harrington RW. Oxidation reactions of a phosphine-borane-stabilised dialkylstannylene. Dalton Transactions 2010, 39(9), 2379-2384.
  • Izod K, Bowman LJ, Wills C, Clegg W, Harrington RW. Synthesis and structural characterisation of alkali metal complexes of heteroatom-stabilised 1,4-and 1,6-dicarbanions. Dalton Transactions 2009, (17), 3340-3347.
  • Izod K, Wills C, Clegg W, Harrington RW. Seven-Membered Cyclic Dialkylstannylene and -Plumbylene Compounds Stabilized by Agostic-type B-H center dot center dot center dot E Interactions [E = Sn, Pb]. Organometallics 2009, 28(7), 2211-2217.
  • Wills C, Izod K, Young J, Clegg W, Harrington RW. Mixed donor-functionalised phosphinomethanide complexes of the alkali metals; synthesis, structures, and solution dynamics. Dalton Transactions 2009, (31), 6159-6165.
  • Izod K, Wills C, Clegg W, Harrington RW. Acyclic Dialkylstannylene and -Plumbylene Compounds That Are Monomeric in the Solid State. Organometallics 2009, 28(19), 5661-5668.
  • Izod K, McFarlane W, Wills C, Clegg W, Harrington RW. Agostic-type B - H⋯Pb interactions stabilize a dialkylplumbylene. Structure of and bonding in [{nPr2P(BH3)}(Me 3Si)C(CH2)]2Pb. Organometallics 2008, 27(17), 4386-4394.
  • Izod K, Wills C, Clegg W, Harrington RW. Metalation of trimethylphosphine-borane. Unexpected reactivity of a simple phosphine-borane-stabilized carbanion toward siloxanes. Organometallics 2007, 26(11), 2861-2866.
  • Izod K, Wills C, Clegg W, Harrington RW. Influence of aromatic ring substituents and co-ligand on the binding mode of a phosphine-borane-stabilized carbanion; crystal structures of [[(Me3Si)2{Ph2P(BH3)}C]KLn]2[Ln = (OEt2)2, pmdeta; pmdeta = N,N,N′,N″,N″-pentamethyldiethylenetriamine]. Journal of Organometallic Chemistry 2007, 692(22), 5060-5064.
  • Izod K, Wills C, Clegg W, Harrington RW. Alkaline earth metal complexes of a phosphine-borane-stabilized carbanion: Synthesis, structures, and stabilities. Inorganic Chemistry 2007, 46(10), 4320-4325.
  • Izod K, Wills C, Clegg W, Harrington RW. Alkali metal complexes of a phosphine-borane-stabilised carbanion: Influence of co-ligands on structure. Dalton Transactions 2007, (33), 3669-3675.
  • Izod K, Wills C, Clegg W, Harrington RW. Synthesis, crystal structure, and solution behavior of a sterically hindered α-metalated phosphine-borane. Organometallics 2006, 25(1), 38-40.
  • Izod K, Wills C, Clegg W, Harrington RW. Heavier alkali metal complexes of a silicon- and phosphine-borane- stabilized carbanion. Organometallics 2006, 25(22), 5326-5332.

• Conference Proceedings (inc. Abstract)

  • Izod K, Wills C, Harrington RW, Clegg W. Agostically-stabilized dialkylstannylenes and plumbylenes. In: Abstracts of Papers of the American Chemical Society: 241st National Meeting of the American Chemical Society. 2011, Anaheim, California, USA: American Chemical Society.