Aims

This module aims to;

1.       Demonstrate the relationship between structure and function of biomolecules

2.       Introduce the molecular basis of cellular processes and the principles that underlie these events

3.       Consider the implications in relation to health and disease

4.       Provide an introduction to experimental methods which can be applied to generate information about biomolecules

Outline Of Syllabus

Lectures and seminars will cover the following topics:

•       Amino acids and proteins: proteins and their building blocks; proteins in health and disease; enzymes; methods used in protein purification.

•       Carbohydrates: the structure of sugars and their role in biology.

•       Nucleic acids: the importance of phosphorus in biology; the relationship between DNA, RNA and proteins; the structure of DNA and how this relates to its function replication; DNA sequencing and the human genome.

•       The control of gene expression: transcription (RNA synthesis) and translation (protein synthesis).

•       Energy and cellular metabolism: glycolysis; citric acid cycle; oxidative phosphorylation; gluconeogenesis; glycogen metabolism; fat metabolism; basic amino acid metabolism; alcohol metabolism.

Teaching Rationale And Relationship

1.       Lectures will define the scope of the course and communicate basic knowledge as a basis for further study.

2.       Structured guided activities, seminars and Q&A sessions will encourage students to develop their knowledge and understanding of the subject, and interpersonal communication skills. They provide an opportunity for students to ask questions and where possible to exchange ideas in a small group setting. Skills practiced include critical thinking, numeracy, communication and team working.

3.       Guided independent study is used for self-directed learning and includes: reading lecture notes and texts; advance preparation for seminars; submitting questions for Q&A sessions; using learning resources on the internet and VLE. Skills practiced include critical thinking, active learning, numeracy, planning and organisation and independence.

Assessment Rationale And Relationship

The end of semester examination assesses knowledge and understanding of the course material.

The formative assessment will support students’ learning by providing an opportunity for students to assess their knowledge and understanding of course material as well as to familiarise students with the end of semester exam format.

FMS Schools offering Semester One modules available as ‘Study Abroad’ will, where required, provide an alternative assessment time for examinations that take place after the Winter vacation. Coursework with submission dates after the Winter vacation will either be submitted at an earlier date or at the same time remotely. The assessment format will not normally vary from the original to ensure learning outcomes are met. Any changes to the original format must meet module learning outcomes and be approved by the school.