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In Vivo Imaging System (IVIS)

Real-time in vivo imaging

Wellcome Trust-funded, this 3D optical imaging system enables non-invasive, real-time monitoring of disease progression, cell trafficking, and gene expression. IVIS software facilitates seamless switching between fluorescence and bioluminescence modes. The IVIS is equipped with a wide field of view for high throughput (up to 5 mice) and a topographic laser scanner for 3D imaging, it features 10 narrow band excitation filters (30nm bandwidth) and 18 narrow band emission filters (20nm bandwidth) for spectral unmixing.

IVIS techniques

  • Bioluminescent
  • Fluorescence
  • Spectral un-mixing
  • Nuclear Imaging (Cerenkov)

Applications

  • Functional genomics
  • Expression profiles and regulation study
  • Protein–Protein Interaction
  • Oncology
  • Infectious disease
  • Stem cell research
  • Tracking and functional analysis
  • Drug discovery
  • Toxicology research
  • Gene delivery and therapy
  • Expression kinetics and localisation

Animal monitoring

IVIS is equipped with an Isoflurane anaesthesia system, temperature controlled stage and a visual image of the scanner field of view. 

Person using IVIS software