BGM2060 : Proteins and Enzymes
- Offered for Year: 2024/25
- Module Leader(s): Dr David Bolam
- Lecturer: Professor Wyatt Yue, Dr Jon Marles-Wright, Professor David Elliott, Dr Elizabeth Veal, Professor Jane Endicott
- Owning School: Biomedical, Nutritional and Sports Scien
- Teaching Location: Newcastle City Campus
Semesters
Your programme is made up of credits, the total differs on programme to programme.
| Semester 2 Credit Value: | 20 |
| ECTS Credits: | 10.0 |
| European Credit Transfer System | |
Aims
The aim of the module is to provide students with a detailed understanding of protein structure, function and application, with particular focus on enzymes.
Outline Of Syllabus
•Properties of proteins and enzymes, macromolecules essential to all life.
•Protein secondary structure, super secondary structure and tertiary folds and introduce key concepts in protein folding, including intrinsically unfolded proteins.
•Specific interactions between enzymes and substrates are determined by protein structure and how preferential binding of the transition state by enzymes leads to catalysis
•Kinetic parameters that describe enzyme catalysis, inhibition and allosteric regulation
•Mechanisms of action of several major enzyme classes to illustrate key catalytic strategies.
•The concept that a protein can carry out more than one function ('moonlighting' proteins)
•Catalysis by RNA and comparison to protein enzymes.
Teaching Methods
Teaching Activities
| Category | Activity | Number | Length | Student Hours | Comment |
|---|---|---|---|---|---|
| Scheduled Learning And Teaching Activities | Lecture | 20 | 1:00 | 20:00 | In person on campus |
| Guided Independent Study | Assessment preparation and completion | 1 | 80:00 | 80:00 | Preparation and completion of lab reports and exam revision |
| Scheduled Learning And Teaching Activities | Practical | 1 | 7:00 | 7:00 | In person on campus |
| Scheduled Learning And Teaching Activities | Practical | 1 | 6:00 | 6:00 | In person on campus |
| Scheduled Learning And Teaching Activities | Small group teaching | 3 | 1:00 | 3:00 | In person seminars - Practical write up guidance and feedback sessions |
| Scheduled Learning And Teaching Activities | Small group teaching | 1 | 2:00 | 2:00 | In peron on campus. Revision seminar to provide opportunities for discussion and clarification of module |
| Guided Independent Study | Independent study | 1 | 82:00 | 82:00 | Writing up lecture notes, revision and general reading |
| Total | 200:00 |
Teaching Rationale And Relationship
The lectures will cover the key points of the module and will be reinforced by the practicals. Seminars offer students an opportunity to discuss their understanding and check their learning against the module outcomes.
The practicals form the core of this module as they will give the students ‘hands-on’ experience of key methods in protein biochemistry, and provide training in data acquisition, interpretation and critical analysis.
Assessment Methods
The format of resits will be determined by the Board of Examiners
Exams
| Description | Length | Semester | When Set | Percentage | Comment |
|---|---|---|---|---|---|
| Written Examination | 90 | 2 | A | 70 | In person invigilated Exam. 4 short answer questions. All questions to be answered |
Other Assessment
| Description | Semester | When Set | Percentage | Comment |
|---|---|---|---|---|
| Practical/lab report | 2 | M | 15 | 1,600 words |
| Practical/lab report | 2 | M | 15 | 1,200 words |
Assessment Rationale And Relationship
Exams test all knowledge across the module.
Practicals assess students understanding of key points in the lectures, ability to report and analyse results, and tests their teamwork skills (students will work in groups of 2) and general laboratory skills.
The practical write up tests data analysis, critical thinking and report-writing skills.
Reading Lists
Timetable
- Timetable Website: www.ncl.ac.uk/timetable/
- BGM2060's Timetable