Staff Profile
Dr Agata Rozanska
Research Associate
- Email: agata.rozanska@ncl.ac.uk
- Address: Biosciences Institute
Faculty of Medical Sciences
Newcastle University
International Centre for Life, Bioscience West Building, Newcastle upon Tyne, NE1 3BZ United Kingdom
Publications
- Hornig-Do H-T, Montanari A, Rozanska A, Tuppen HA, Almalki AA, Abg-Kamaludin DP, Frontali L, Francisci S, Lightowlers RN, Chrzanowska-Lightowlers ZM. Human mitochondrial leucyl tRNA synthetase can suppress non cognate pathogenic mt-tRNA mutations. EMBO Molecular Medicine 2014, 6(2), 183-193.
- Serre V, Rozanska A, Beinat M, Chretien D, Boddaert N, Munnich A, Rötig A, Chrzanowska-Lightowlers ZM. Mutations in mitochondrial ribosomal protein MRPL12 leads to growth retardation, neurological deterioration and mitochondrial translation deficiency. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2013, 1832(8), 1304-1312.
- Grellscheid SN, Dalgliesh C, Rozanska A, Grellscheid D, Bourgeois CF, Stevenin J, Elliott DJ. Molecular design of a splicing switch responsive to the RNA binding protein Tra2β. Nucleic Acids Research 2011, 39(18), 8092-8104.
- Rozanska A, Richter-Dennerlein R, Rorbach J, Gao F, Lewis RJ, Chrzanowska-Lightowlers ZM, Lightowlers RN. The human RNA-binding protein RBFA promotes the maturation of the mitochondrial ribosome. Biochemical Journal 2017, 474(13), 2145-2158.
- Zaganelli S, Rebelo-Guiomar P, Maundrell K, Rozanska A, Pierredon S, Powell CA, Jourdain AA, Hulo N, Lightowlers RN, Chrzanowska-Lightowlers ZM, Minczuk M, Martinou J-C. The pseudouridine synthase RPUSD4 is an essential component of mitochondrial RNA granules. Journal of Biological Chemistry 2017, 292(11), 4519-4532.
- Spahr H, Rozanska A, Li XP, Atanassov I, Lightowlers RN, Chrzanowska-Lightowlers ZMA, Rackham O, Larsson NG. SLIRP stabilizes LRPPRC via an RRM-PPR protein interface. Nucleic Acids Research 2016, 44(14), 6868-6882.
- Lightowlers RN, Rozanska A, Chrzanowska-Lightowlers ZM. Mitochondrial protein synthesis: Figuring the fundamentals, complexities and complications, of mammalian mitochondrial translation. FEBS Letters 2014, 588(15), 2496-2503.