Staff Profile

Background:

2020-present   Research Associate in Biosciences Institute, Center for Life, Newcastle University

2018-2019   Research Assistant in Human Developmental Biology Resource (HDBR), Newcastle University

Qualification: 

PhD - Institution of Genetic Medicine, Newcastle University.

MRes - Biomedical Sciences and Translational Medicine, University of Liverpool.

Publications:

See Publication section

• Articles

  • Derrick CJ, Szenker-Ravi E, Santos-Ledo A, Alqahtani A, Yusof A, Eley L, Coleman AHL, Tohari S, Ng AY-J, Venkatesh B, Alharby E, Mansard L, Bonnet-Dupeyron M-N, Roux A-F, Vache C, Roume J, Bouvagnet P, Almontashiri NAM, Henderson DJ, Reversade B, Chaudhry B. Functional analysis of germline VANGL2 variants using rescue assays of vangl2 knockout zebrafish. Human Molecular Genetics 2024, 33(2), 150-169.
  • Eley L, Richardson RV, Alqahtani A, Chaudhry B, Henderson DJ. eNOS plays essential roles in the developing heart and aorta linked to disruption of Notch signalling. Disease Models & Mechanisms 2024, 17(1), dmm050265.
  • Henderson DJ, Alqahtani A, Chaudhry B, Cook A, Eley L, Houyel L, Hughes M, Keavney B, de la Pompa JL, Sled J, Spielmann N, Teboul L, Zaffran S, Mill P, Liu KJ. Beyond genomic studies of congenital heart defects through systematic modelling and phenotyping. DMM Disease Models and Mechanisms 2024, 17(11), dmm050913.
  • Queen R, Crosier M, Eley L, Kerwin J, Turner JE, Yu J, Alqahtani A, Dhanaseelan T, Overman L, Soetjoadi H, Baldock R, Coxhead J, Boczonadi V, Laude A, Cockell SJ, Kane MA, Lisgo S, Henderson DJ. Spatial transcriptomics reveals novel genes during the remodelling of the embryonic human arterial valves. PLoS Genetics 2023, 19(11).
  • Alqahtani A, Skelton A, Eley L, Annavarapu S, Henderson DJ, Chaudhry B. Isolation and next generation sequencing of archival formalin-fixed DNA. Journal of Anatomy 2020, 237(3), 587-600.
  • Santos-Ledo A, Washer S, Dhanaseelan T, Eley L, Alqatani A, Chrystal PW, Papoutsi T, Henderson DJ, Chaudhry B. Alternative splicing of jnk1a in zebrafish determines first heart field ventricular cardiomyocyte numbers through modulation of hand2 expression. PLoS Genetics 2020, 16(5), e1008782.
  • Richardson R, Eley L, Donald-Wilson C, Davis J, Curley N, Alqahtani A, Murphy L, Anderson RH, Henderson DJ, Chaudhry B. Development and maturation of the fibrous components of the arterial roots in the mouse heart. Journal of Anatomy 2018, 232(4), 554-567.
  • Eley L, Alqahtani A, MacGrogan D, Richardson R, Murphy L, Salguero-Jimenez A, Rodriguez San Pedro M, Tiurma S, McCutcheon L, Gilmore A, de La Pompa JL, Chaudhry B, Henderson D. A novel source of arterial valve cells linked to bicuspid aortic valve without raphe in mice. eLife 2018, 7, e34110.
  • Crucean A, Alqahtani A, Barron DJ, Brawn WJ, Richardson RV, O'Sullivan J, Anderson RH, Henderson DJ, Chaudhry B. Re-evaluation of hypoplastic left heart syndrome from a developmental and morphological perspective. Orphanet Journal of Rare Diseases 2017, 12, 138.
  • Kumar JD, Holmberg C, Kandola S, Steele I, Hegyi P, Tiszlavicz L, Jenkins R, Beynon RJ, Peeney D, Giger OT, Alqahtani A, Wang TC, Charvat TT, Penfold M, Dockray GJ, Varro A. Increased expression of chemerin in squamous esophageal cancer myofibroblasts and role in recruitment of mesenchymal stromal cells. PLoS ONE 2014, 9(7), e104877.

• Review

  • Chaudhry B, Alqahtani A, Eley L, Coats L, Moldovan C, Annavarapu SR, Henderson DJ. The Left Ventricular Myocardium in Hypoplastic Left Heart Syndrome. Journal of Cardiovascular Development and Disease 2022, 9(8), 279.