Staff Profile
Dr Bethany Dennis
Research Associate
- Email: bethany.dennis@ncl.ac.uk
- Address: Biosciences Institute
Medical School
Framlington Place
Newcastle upon Tyne
NE2 4HH
Background
My work has primarily centered around neuropharmacology, neuroinflammation and in vitro electrophysiology. I completed my PhD in Neuroscience at Newcastle Unviversity in January 2025, after 7 years part-time study. Previously, I completed my Neuroscience MRes at Newcastle University, between 2016 and 2017, and Biology BSc at Liverpool John Moores University between 2013 and 2016.
Research
Primarily, my research interests focus on cortical network dynamics and the interplay between excitatory and inhibitory neurons. Imbalance in these neuronal networks underlie a variety of neurological and neuropsychiatric diseases. My research aims to understand the changes causing these imbalances, and find thereapeutic targets to restore normal network function.
Publications
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Articles
- Al-Musawi I, Dennis BH, Clowry GJ, LeBeau FE. Evidence of prodromal changes in neuronal excitability and neuroinflammation in the hippocampus in young alpha-synuclein (A30P) transgenic mice. Frontiers in Dementia 2024, 3, 1404841.
- Dennis BH, Neale SA, LeBeau FEN, Salt TE. Modulation of circuit oscillations in the rat anterior cingulate cortex (ACC) in vitro by mGlu2 metabotropic glutamate receptors and alleviation of the effects of phencyclidine-induced NMDA-receptor hypofunction. Pharmacology Biochemistry and Behavior 2023, 223, 173532.
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Review
- Olkhova EA, Smith LA, Dennis BH, Ng YS, LeBeau FEN, Gorman GS. Delineating mechanisms underlying parvalbumin neuron impairment in different neurological and neurodegenerative disorders: the emerging role of mitochondrial dysfunction. Biochemical Society Transactions 2024, 52(2), 553-565.