Staff Profile
Dr David Austin
Consultant Cardiologist and Honorary Clinical Senior Lecturer
- Email: david.austin@ncl.ac.uk
- Personal Website: https://www.southtees.nhs.uk/about/strive/research-team/academic-cardiovascular-unit/about-the-acu/
- Address: Academic Cardiovascular Unit
The James Cook University Hospital
Marton Road
Middlesbrough
TS4 3BW
Dr David Austin is a Consultant Cardiologist at The James Cook University Hospital, Middlesbrough, South Tees NHS Foundation Trust and Honorary Senior Clinical Lecturer at Newcastle University, UK.
He trained in medicine at the University of Aberdeen and then completed early professional training and MD at the University of Glasgow. Dr Austin completed cardiology specialist training at the Freeman Hospital, Newcastle and The James Cook University Hospital, Middlesbrough before undertaking an Interventional Cardiology Fellowship in Halifax, Canada in 2013 to 2014.
In addition to establishing grant-funded trials within cardiology at James Cook University Hospital, Dr Austin is the co-director of the Academic Cardiovascular Unit and Fellow of the Royal College of Physicians and Surgeons of Glasgow and serves on the executive of the Tees Valley Research Alliance.
Dr Austin has research interests in cardio-oncology, in particular multi-centre clinical trial research, and was chief investigator in the PROACT randomised controlled trial. Further notable clinical trial work led from Newcastle University are the phase II TACTIC and FRACTAL randomised controlled trials, and ongoing IMMUNE DCM cohort study. In addition, Dr Austin has extensive experience on phase 2 and 3 clinical trials in Cardiology and leads the South Tees NHS FT cardiovascular research team, recruiting to 25 clinical trials currently. Dr Austin has a particular interest in the field of athero-thrombosis, and was co-author on the SENIOR RITA, THYRAMI and DAPA MI clinical trials.
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Articles
- Miller CA, Al-Mohammad A, Columbine E, Cotterell D, Fisher S, Hartshorne-Evans N, Humphreys-Davies L, Hyland R, Lumbers RT, McCann GP, Paton MF, Petrie MC, Robinson S, Sudlow C, Humphreys-Davies L, Hartshorne-Evans N, Cleverley R, Smith A, Wardle M, Worsnop S, Lumbers RT, Manisty C, Moon J, Petersen SE, Balakrishnan Nair S, Sudlow C, Clegg A, Gosai J, Shanmuganathan M, Bhagra C, Deaton C, Bateman J, Llewellyn J, Williams R, Venkatamaran A, Schiff R, Clark AL, Mayet J, Wilkins MR, Penn LA, Le Page P, O Driscoll S, Shah AM, Zakeri R, O Gallagher K, Mayr M, Gatenby K, Greenwood JP, Plein S, Kanagala P, Miller CA, Soltani F, Arnold R, Kunhunny S, McDiarmid AK, Zaman A, Petrie MC, Berry C, Dweck M, Lang C, Mordi I, Garg P, Dewhurst M, Hann K, Ripley DP, Green T, Magdy F, Neubauer S, Rider O, Prasad SK, Bucciarelli-Ducci C, Ludman AJ, Bakhai A, Jackson T, Al-Mohammad A, Austin D, Chapman M, Beezer J, Beezer J, Campbell P, Anderson LJ, Flett A, Haydock P, Patel P, Steeds R, Banerjee P, Chahal R, McCann GP, Squire I, Dodd S, Peek N. Rationale and design of the United Kingdom Heart Failure with Preserved Ejection Fraction Registry. Heart 2024, 110(5), 359-365.
- Austin D, Maier RH, Akhter N, Sayari M, Ogundimu E, Maddox JM, Vahabi S, Humphreys AC, Graham J, Oxenham H, Haney S, Cresti N, Verrill M, Osborne W, Wright KL, Goranova R, Bailey JR, Kalakonda N, Macheta M, Kilner MF, Young ME, Morley NJ, Neelakantan P, Gilbert G, Thomas BK, Graham RJ, Fujisawa T, Mills NL, Hildreth V, Prichard J, Kasim AS, Hancock HC, Plummer C. Preventing Cardiac Damage in Patients Treated for Breast Cancer and Lymphoma: The PROACT Clinical Trial. JACC: CardioOncology 2024, 6(5), 684–696.
- Loh SX, Ekinci Y, Spray L, Jeyalan V, Olin T, Richardson G, Austin D, Alkhalil M, Spyridopoulos I. Fractalkine Signalling (CX3CL1/CX3CR1 Axis) as an Emerging Target in Coronary Artery Disease. J. Clin. Med 2023, 12(14), 4821.
- Burgoine T, Austin D, Wu J, Quinn T, Shurmer P, Gale CP, Wilkinson C. Automated external defibrillator location and socioeconomic deprivation in Great Britain. Heart 2023, 110(3), 188-194.
- Bawamia B, Spray L, Wangsaputra VK, Bennaceur K, Vahabi S, Stellos K, Kharatikoopaei E, Ogundimu E, Gale CP, Keavney B, Maier R, Hancock H, Richardson GD, Austin D, Spyridopoulos I. Activation of telomerase by TA-65 enhances immunity and reduces inflammation post myocardial infarction Randomized Pilot Trial. GeroScience 2023, 45, 2689-2705.
- Jabbar A, Ingoe L, Thomas H, Carey P, Junejo S, Addison C, Vernazza J, Austin D, Greenwood JP, Zaman A, Razvi S. Prevalence, Predictors and Outcomes of Thyroid Dysfunction in patients with Acute Myocardial Infarction: the ThyrAMI-1 Study. Journal of Endocrinological Investigation 2021, 44, 1209-1218.
- Maier R, Bawamia B, Bennaceur K, Dunn S, Marsay L, Amoah R, Kasim A, Filby A, Austin D, Hancock H, Spyridopoulos I. Telomerase activation to reverse immunosenescence in elderly patients with acute coronary syndrome: Protocol for a randomized pilot trial. JMIR Research Protocols 2020, 9(9), e19456.
- Razvi S, Leng O, Jabbar A, Bano A, Ingoe L, Addison C, Thomas H, Carey P, Junejo S, Austin D, Greenwood JP, Zaman A. Sample Timing, Diagnosis of Subclinical Thyroid Dysfunction and Mortality in Acute Myocardial Infarction: ThyrAMI1 Study. Journal of Clinical Endocrinology and Metabolism 2020, 105(4), e1299–e1306.
- Bawamia BR, Egred M, Jackson M, Purcell I, Austin D, Zaman AG. Percutaneous coronary intervention for left main stem disease: Impact of diabetes mellitus on mortality. Catheterization and Cardiovascular Interventions 2020, 96(4), E416-E422.
- Jabbar A, Ingoe L, Junejo S, Carey P, Addison C, Thomas H, Parikh JD, Austin D, Hollingsworth KG, Stocken DD, Pearce SHS, Greenwood JP, Zaman A, Razvi S. Effect of levothyroxine on left ventricular ejection fraction in patients with subclinical hypothyroidism and acute myocardial infarction: a randomized clinical trial. JAMA: The Journal of the American Medical Association 2020, 324(3), 249-258.
- Jackson M, Austin D, Kwok CS, Rashid M, Kontopantelis E, Ludman P, de Belder M, Mamas MA, Zaman A. The impact of diabetes on the prognostic value of left ventricular function following percutaneous coronary intervention: Insights from the British Cardiovascular Intervention Society. Catheterization and Cardiovascular Interventions 2018, 92(6), E393-E402.
- Austin D, Yan AT, Spratt JC, Kunadian V, Edwards RJ, Egred M, Bagnall AJ. Patient characteristics associated with self-presentation, treatment delay and survival following primary percutaneous coronary intervention. European Heart Journal: Acute Cardiovascular Care 2014, 3(3), 214-222.
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Reviews
- Schuth U, Gill K, Telyuk P, Bawamia B-R, Austin D, Zaman A. Role of Lipoprotein(a) Reduction in Cardiovascular Disease. Journal of Clinical Medicine 2024, 13(21), 6311.
- Jeyalan V, Austin D, Loh SX, Wangsaputra VK, Spyridopoulos I. Fractalkine/CX3CR1 in Dilated Cardiomyopathy: A Potential Future Target for Immunomodulatory Therapy?. Cells 2023, 12(19), 2377.