Staff Profile
Jack Roberts
Research Assistant
- Email: jack.roberts@ncl.ac.uk
- Personal Website: https://research.ncl.ac.uk/ricelab/
- Address: Biosciences Institute
Newcastle University
International Centre for Life
NE1 3BZ
I am a research assistant with Dr Sarah Rice. Our research focuses on understanding molecular genetic and epigenetic mechanisms of osteoarthritis risk. In addition, the Rice lab uses a range of in-vitro techniques to characterise the phenotypic effects of these molecular mechanisms in cellular models of mature cartilage, bone and synovium as well as during development.
QUALIFICATIONS
BSc (Hons) Biology - Manchester Metropolitan University
MRes Medical Genetics - Newcastle University
Roberts JB, Boldvig OL, Aubourg G, Kanchenapally ST, Deehan DJ, Rice SJ, Loughlin J. Specific isoforms of the ubiquitin ligase gene WWP2 are targets of osteoarthritis genetic risk via a differentially methylated DNA sequence. Arthritis Research & Therapy. 2024 Apr 3;26(1):78.
Roberts JB, Rice SJ. Osteoarthritis as an Enhanceropathy: Gene Regulation in Complex Musculoskeletal Disease. Current Rheumatology Reports. 2024 Mar 2:1-3.
Rice SJ, Roberts JB, Tselepi M, Brumwell A, Falk J, Steven C, Loughlin J. Genetic and epigenetic fine‐tuning of TGFB1 expression within the human osteoarthritic joint. Arthritis & Rheumatology. 2021 Oct;73(10):1866-77.
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Article
- Rice SJ, Roberts JB, Tselepi M, Brumwell A, Falk J, Steven C, Loughlin J. Genetic and Epigenetic Fine-Tuning of TGFB1 Expression Within the Human Osteoarthritic Joint. Arthritis and Rheumatology 2021, 73(10), 1866-1877.