Staff Profile
Dr Lou Sutcliffe
Data Manager
- Address: Floor 2
Biomedical Research Building
Newcastle University
Campus for Ageing and Vitality
Newcastle upon Tyne
NE4 5PL
Research Experience
My background is in clinical trials and clinical research, and I have worked across this area in academia, the NHS, and the private sector in pharmaceutical/biopharmaceutical companies and contract research organisations. I am currently the Data Manager for the Mobilise-D consortium. Previous roles at Newcastle include managing clinical trials for the Stroke Research Group and research associate with Helen Phillips and Judith Goodship's groups working on studies of the genetics of congenital heart disease and heart development in the Institute of Genetic Medicine. Other previous experience includes recruiting heart and kidney transplant patients for the Institute of Transplantation Biobank, and knee replacement patients in the Freeman Hospital, and as technical administrator managing SOPs and regulatory documentation for a clinical trials pathology laboratory at a CRO.
Qualifications
PhD Biology Durham University CASE Studentship with Lonza Biologics 2008-2012 "Chemical genetic dissection of efferent IRE1a signalling" - Investigating protein folding mechanisms as a way to improve biopharmaceutical yields and quality. http://etheses.dur.ac.uk/5943/
BSc Hons Pharmacology with Industrial Experience 2001-2005 University of Manchester
Publications
See publications tab,
Acknowledged for patient recruitment/tissue collection in:
Dixon D, Coates J, del Carpio Pons A, Horabin J, Walker A, Abdul N, Kalson NS, Brewster NT, Weir DJ, Deehan DJ, Mann DA, Borthwick LA. A potential mode of action for Anakinra in patients with arthrofibrosis following total knee arthroplasty. Sci Rep. 2015 Nov 10;5:16466.
Parry SW, Deary V, Finch T, Bamford C, Sabin N, McMeekin P, O'Brien J, Caldwell A, Steen N, Whitney SL, Macdonald C, McColl E. The STRIDE (Strategies to Increase confidence, InDependence and Energy) study: cognitive behavioural therapy-based intervention to reduce fear of falling in older fallers living in the community - study protocol for a randomised controlled trial. Trials. 2014 Jun 6;15:210. doi: 10.1186/1745-6215-15-210. PubMed PMID: 24906406; PubMed Central PMCID: PMC4059076.
I am currently working for the Mobilise-D consortium https://www.mobilise-d.eu/
If you are looking for information on the Feeding After Stroke Project, please see the below Privacy Notice:
Privacy Notice: The Feeding After Stroke Project
1. The Data Controller for this project is:
- Dr Christopher Price Newcastle University 3-4 Claremont Terrace Newcastle upon Tyne NE2 4AE United Kingdom E-Mail: C.I.M.Price@Newcastle.ac.uk
2. Data used for this project includes:
- Numbers of patients who were admitted to hospital in England with a stroke;
- Numbers of stroke patients who had an operation known as a “percutaneous endoscopic gastrostomy” (PEG);
- Numbers of stroke patients in each age category.
- Numbers of stroke patients in each gender category.
- Numbers of stroke patients in each ethnic origin category
- Numbers of stroke patients in each area of England at the time of their admission to hospital with a stroke.
3. It is not necessary to personally identify any patient for the purposes of this research, nor will any attempt be made to do so. The researchers will only have access to combined stroke patient data.
4. The data is collected from: Hospital Episode Statistics and the Office of National Statistics via NHS Digital.
5. The purpose for processing the data is: To help improve the care of stroke patients.
6. The data provided by NHS Digital will not be shared with anyone outside the research team.
7. The legal basis for processing the data is: Public task: the processing is necessary for us to perform a task in the public interest.
8. The University's current Data Protection Officer is: Maureen Wilkinson.
You can contact Newcastle University's Data Protection Officer at the following address:
- IT Service Claremont Tower Claremont Road Newcastle upon Tyne NE1 7RU Email: rec-man@ncl.ac.uk
9. You have a number of rights under the GDPR in relation to the data held about you. For more detail on these rights and how to exercise them, see the university’s Data Subject Rights web pages.
10. If you are unhappy with our use or storage of your data, you have the right to complain to the Information Commissioner's Office ("ICO") about this. Please see the ICO website for more details of how to complain.
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Articles
- Sutcliffe L, Lumley H, Shaw L, Francis R, Price CI. Surface Electroencephalography (EEG) During the Acute Phase of Stroke to Assist With Diagnosis and Prediction of Prognosis: a Scoping Review. BMC Emergency Medicine 2022, 22, 29.
- Sutcliffe L, Flynn D, Price CI. Percutaneous endoscopic gastrostomy and mortality post-stroke in England from 2007 to 2018: a retrospective cohort study. Stroke 2020, 51(12), 3658-3663.
- Price CI, Shaw L, Islam S, Javanbakht M, Watkins A, McMeekin P, Snooks S, Flynn D, Francis R, Lakey R, Sutcliffe L, McClelland G, Lally J, Exley C, Rodgers H, Russell I, Vale L, Ford GA. Effect of an Enhanced Paramedic Acute Stroke Treatment Assessment (PASTA) on Thrombolysis Delivery During Emergency Stroke Care: A Cluster Randomised Clinical Trial. JAMA Neurology 2020, 77(7), 840-848.
- Price CI, Shaw L, Dixit A, Graziadio S, Lendrem C, Mitra D, Rodgers H, Sutcliffe L, White P. Asymmetrical Bioimpedance in the Anterior Circulation for Urgent Stratification of suspected Stroke (ABACUS Stroke): study protocol for a diagnostic accuracy study. Diagnostic and Prognostic Research 2020, 4, 2.
- Da-Silva RH, Moore SA, Rodgers H, Shaw L, Sutcliffe L, van Wijck F, Price CI. Wristband Accelerometers to motiVate arm Exercises after Stroke (WAVES): a pilot randomized controlled trial. Clinical Rehabilitation 2019, 33(8), 1391-1403.
- Price CI, Shaw L, Dodd P, Exley C, Flynn D, Francis R, Islam S, Javanbakht M, Lakey R, Lally J, McClelland G, McMeekin P, Rodgers H, Snooks H, Sutcliffe L, Tyrell P, Vale L, Watkins A, Ford GA. Paramedic Acute Stroke Treatment Assessment (PASTA): study protocol for a randomised controlled trial. Trials 2019, 20, 121.
- Page DJ, Miossec MJ, Williams SG, Monaghan RM, Fotiou F, Cordell HJ, Sutcliffe L, Topf A, Bourgey M, Bourque G, Eveleigh R, Dunwoodie SL, Winlaw DS, Bhattacharya S, Breckpot J, Devriendt K, Gewillig M, Brook JD, Setchfield KJ, Bu'Lock F, O'Sullivan JJ, Stuart G, Bezzina CR, Mulder BJM, Postma AV, Bentham JR, Baron M, Bhaskar SS, Black GC, Newman WG, Hentges KE, Lathrop GM, Santibanez-Koref M, Keavney B. Whole Exome Sequencing Reveals the Major Genetic Contributors to Nonsyndromic Tetralogy of Fallot. Circulation Research 2018, 124(4), 553-563.
- Brown M, Strudwick N, Suwara M, Sutcliffe LK, Mihai AD, Ali AA, Watson JN, Schröder M. An initial phase of JNK activation inhibits cell death early in the endoplasmic reticulum stress response. Journal of Cell Science 2016, 129(12), 2317-2328.
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Book Chapter
- Schröder M, Sutcliffe L. Consequences of stress in the secretory pathway: The ER stress response and its role in the metabolic syndrome. In: Peter Bross and Niels Gregersen, ed. Protein Misfolding and Cellular Stress in Disease and Aging: Concepts and Protocol. New York: Humana Press, 2010, pp.43-62.
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Conference Proceedings (inc. Abstracts)
- Da Silva R, Rodgers H, Shaw L, van Wijck F, Moore SA, Jackson D, Francis R, Sutcliffe L, Balaam M, Ploetz T, Brkic L, Price CI. Wristband accelerometers to motivate arm exercise after stroke (WAVES): Activity data from a pilot randomised controlled trial. In: 12th World Congress of the International Society of Physical and Rehabilitation Medicine. 2018, Paris: Elsevier Masson SAS.
- Da Silva RH, Moore SA, Van Wijck F, Shaw L, Rodgers H, Jackson D, Balaam M, Sutcliffe L, Brkic L, Ploetz T, Price CI. Proceedings of SRR: Wristband accelerometers to motivate arm exercise after stroke (WAVES): A pilot randomized controlled trial. In: The Society of Research in Rehabilitation 40th Anniversary and Winter Meeting. 2018, Bristol, UK: SAGE Publications Ltd.
- Sutcliffe L, Flynn D, Price CIM. Percutaneous endoscopic gastrostomy insertion after stroke in England 2006–2015: frequency and outcomes. In: UK Stroke Forum. 2017, Liverpool: International Journal of Stroke. In Preparation.
- Goodship J, Miossec M, Brown D, Wilson I, Sutcliffe L, Topf A, Devriendt K, Rauch A, Winlaw D, Bu'Lock F, Bhattacharya S, Lathrop M, Keavney B, Santibanez-Koref M. Analysis of rare variants and CNVs in non-syndromic tetralogy of Fallot. In: American Society of Human Genetics Annual Meeting (ASHG). 2015, Baltimore.