Staff Profile
Dr Lyndsey Butterworth
Research Associate
- Email: lyndsey.butterworth@ncl.ac.uk
- Telephone: +44(0)191 2086291
- Address: Wellcome Trust Centre for Mitochondrial Research, Institute of Neuroscience, Newcastle University, Medical School (M4021), Framlington Place, Newcastle upon Tyne, NE2 4HH
Publications
- Craven L, Herbert M, Murdoch A, Murphy J, Davies JL, Turnbull DM. Research into Policy: A Brief History of Mitochondrial Donation. Stem Cells 2016, 34(2), 265-267.
- Hyslop LA, Blakeley P, Craven L, Richardson J, Fogarty NME, Fragouli E, Lamb M, Wamaitha SE, Prathalingam N, Zhang Q, O'Keefe H, Takeda Y, Arizzi L, Alfarawati S, Tuppen H, Irving L, Kalleas D, Choudhary M, Wells D, Murdoch AP, Turnbull DM, Niakan KK, Herbert M. Towards clinical application of pronuclear transfer to prevent mitochondrial DNA disease. Nature 2016, 534(7607), 383-386.
- Craven L, Irving L, Alston CL, Watson EL, Byerley S, McFarland R, Stewart JA, Taylor RW, Herbert M, Turnbull DM. Preimplantation genetic diagnosis for mitochondrial DNA disease. In: 13th Annual Preimplantation Genetic Diagnosis International Society (PGDIS) Meeting. 2014, Canterbury, UK: Springer.
- Chinnery PF, Craven L, Mitalipov S, Stewart JB, Herbert M, Turnbull DM. The Challenges of Mitochondrial Replacement. PLoS Genetics 2014, 10(4), e1004315.
- Greggains GD, Lister LM, Tuppen HAL, Zhang Q, Needham LH, Prathalingam N, Hyslop LA, Craven L, Polanski Z, Murdoch AP, Turnbull DM, Herbert M. Therapeutic potential of somatic cell nuclear transfer for degenerative disease caused by mitochondrial DNA mutations. Scientific Reports 2014, 4, 3844.
- Craven L, Irving L, Herbert M, Turnbull D. Development of the Pronuclear Transfer Technique to Prevent Transmission of Mitochondrial DNA Disease in Humans. In: UK Neuromuscular Translational Research Conference. 2012, Newcastle upon Tyne, UK: Elsevier.
- Irving L, Alston C, Craven L, Herbert M, Turnbull DM. Analysis of mitochondrial DNA mutant loads in oocytes & preimplantation embryos for the 14709T > C & 14487T > C mtDNA mutations by pyrosequencing. In: United Kingdom Neuromuscular Translational Research Conference. 2011, London, UK: Elsevier.
- Irving L, Craven L, Herbert M, Turnbull DM. Manipulation of human abnormally fertilized pronuclear stage zygotes following vitrification. In: United Kingdom Neuromuscular Translational Research Conference. 2011, London, UK: Elsevier.
- Craven L, Elson JL, Irving L, Tuppen HA, Lister LM, Greggains GD, Byerley S, Murdoch AP, Herbert M, Turnbull D. Mitochondrial DNA disease: new options for prevention. Human Molecular Genetics 2011, 20(R2), R168-R174.
- Craven L, Tuppen HA, Greggains GD, Harbottle SJ, Murphy JL, Cree LM, Murdoch AP, Chinnery PF, Taylor RW, Lightowlers RN, Herbert M, Turnbull DM. Pronuclear transfer in human embryos to prevent transmission of mitochondrial DNA disease. Nature 2010, 465(7294), 82-85.
- Gardner JL, Craven L, Turnbull DM, Taylor RW. Experimental Strategies Towards Treating Mitochondrial DNA Disorders. Bioscience Reports 2007, 27(1-3), 139-150.
- Brown D, Herbert M, Lamb V, Chinnery PF, Taylor R, Lightowlers R, Craven L, Cree L, Gardner JL, Turnbull DM. Transmission of mitochondrial DNA disorders: possibilities for the future. Lancet 2006, 368(9529), 87-89.