Staff Profile
Dr Magomet Aushev
Research Associate
- Email: mag.aushev@ncl.ac.uk
- Address: Biosciences Institute
International Centre for Life
Newcastle University
Central Parkway
Newcastle upon Tyne
NE1 3BZ
Background
Position
Postdoctoral research associate in the lab of Prof. Mary Herbert.
Qualifications
2016 - Ph.D. in Applied Genetics, Newcastle University
2012 - M.Res. in Stem Cells and Regenerative Medicine, Newcastle University
2011 - B.Sc. (Hons) in Biotechnology, Newcastle University
Publications
- Cavazza T, Takeda Y, Politi AZ, Aushev M, Aldag P, Baker C, Choudhary M, Bucevicius J, Lukinavicius G, Elder K, Blayney M, Lucas-Hahn A, Niemann H, Herbert M, Schuh M. Parental genome unification is highly error-prone in mammalian embryos. Cell 2021, 184(11), 2860-2877.e22.
- Imahorn E, Aushev M, Herms S, Hoffmann P, Cichon S, Reichelt J, Itin PH, Burger B. Gene expression is stable in a complete CIB1 knockout keratinocyte model. Scientific Reports 2020, 10(1), 14952.
- Aushev M, Herbert M. Mitochondrial genome editing gets precise. Nature 2020, 583(7817), 521-522.
- Renz P, Imahorn E, Spoerri I, Aushev M, March OP, Wariwoda H, Von Arb S, Volz A, Itin PH, Reichelt J, Burger B. Arginine- but not alanine-rich carboxy-termini trigger nuclear translocation of mutant keratin 10 in ichthyosis with confetti. Journal of Cellular and Molecular Medicine 2019, 23(12), 8442-8452.
- Aushev M, Koller U, Mussolino C, Cathomen T, Reichelt J. Traceless targeting and isolation of gene edited immortalised keratinocytes from epidermolysis bullosa simplex patients. Molecular Therapy: Methods & Clinical Development 2017, 6, 112-123.
- Imahorn E, Aushev M, March O, de Jong SJ, Jouanguy E, Casanova J, Itin P, Reichelt J, Burger B. A keratinocyte culture model for epidermodysplasia verruciformis. In: 46th ESDR Annual Meeting. 2016, Munich, Germany: Elsevier.
- March ONP, Aushev M, Koller U, Reichelt J. Developing an optimised TALEN-mediated ex vivo gene therapy for epidermolytic ichthyosis. In: Changing the Face of Modern Medicine: Stem Cells and Gene Therapy. 2016, Florence, Italy: Mary Ann Liebert, Inc. Publishers.
- March O, Aushev M, Koller U, Reichelt J. Gene editing of keratinocyte stem cells for a novel ex vivo epidermolytic ichthyosis therapy. In: 43nd Annual Meeting of theArbeitsgemeinschaftDermatologische Forschung e.V.(ADF). 2016, Vienna, Austria: Wiley-Blackwell.
- March O, Aushev M, Koller U, Reichelt J. Optimised TALEN-mediated gene editing of keratinocyte stem cells for a novel ex vivo epidermolytic ichthyosis therapy. In: ESDR 2016 Annual Meeting. 2016, Munich, Germany: Elsevier.
- Reichelt J, March O, Aushev M, Koller U. Optimised TALEN-mediated Gene Editing of Keratinocyte Stem Cells for a Novel Ex Vivo Epidermolytic Ichthyosis Therapy. In: British Skin Foundation, Skin Deep - 20 Years of Research, 20th Anniversary Conference. 2016, London: Wiley-Blackwell Publishing Ltd.
- Aushev M, Mussolino C, Cathomen T, Reichelt J. TALEN-mediated elimination of mutant keratin 14 as a gene therapy for epidermolysis bullosa simplex. In: 42nd Annual Meeting of the Arbeitsgemeinschaft Dermatologische Forschung e.V. (ADF). 2016, Vienna, Austria: Wiley-Blackwell Publishing Ltd.
- Aushev M, Mussolino C, Cathomen T, Reichelt J. TALEN-mediated elimination of mutant keratin 14 as a gene therapy for epidermolysis bullosa simplex. In: Society for Investigative Dermatology (SID) Annual Meeting. 2016, Scottsdale, Arizona: Elsevier.
- March O, Aushev M, Reichelt J. A TALEN-mediated gene therapy for epidermolytic ichthyosis. In: British Society for Investigative Dermatology Annual Meeting. 2015, Southampton, UK: Wiley-Blackwell.
- March O, Aushev M, Mussolino C, Cathomen T, Reichelt J. A TALEN-mediated gene therapy for epidermolytic ichthyosis. In: British Society for Gene and Cell Therapy Annual Conference. 2015, Glasgow, UK: Mary Ann Liebert, Inc. Publishers.
- Aushev M, Reichelt J. Functional inactivation of mutant keratin 14 as a gene therapy for epidermolysis bullosa simplex using programmable nucleases. In: British Society of Investigative Dermatology Meeting 2015. 2015, Southampton, UK: Wiley-Blackwell.
- Aushev M, Mussolino C, Cathomen T, Reichelt J. TALEN-mediated elimination of mutant keratin 14 as a gene therapy for epidermolysis bullosa simplex. In: British Society for Gene and Cell Therapy Annual Conference. 2015, Glasgow, UK: Mary Ann Liebert, Inc.
- Aushev M, Itin PH, Reichelt J, Burger B. Engineering a model system for ichthyosis with confetti. In: British Society of Investigative Dermatology Annual Meeting. 2014, Newcastle: British Journal of Dermatology: John Wiley & Sons, Inc.
- Aushev M, Mussolino C, Cathomen T, Torma H, Reichelt J. Molecular surgery for epidermolysis bullosa simplex. In: British Society of Investigative Dermatology Annual Meeting. 2014, Newcastle upon Tyne, UK: Wiley-Blackwell.