Staff Profile | Faculty of Medical Sciences

Moira Crosier

Research Associate

Email: moira.crosier@ncl.ac.uk
Telephone: +44 (0) 191 241 8646
Address: Biosciences Institute
Faculty of Medical Sciences
Newcastle University
Biomedicine West Wing
International Centre for Life
Times Square
Newcastle upon Tyne
NE1 4EP

Publications

Alzu'bi A, Sankar N, Crosier M, Kerwin J, Clowry GJ. Tyramide signal amplification coupled with multiple immunolabeling and RNAScope in situ hybridization in formaldehyde-fixed paraffin-embedded human fetal brain. Journal of Anatomy 2022, 241(1), 33-41.
Chacko LJ, Lahlou H, Steinacher C, Assou S, Messat Y, Dudas J, Edge A, Crespo B, Crosier M, Sergi C, Schrott-Fisher A, Zine A. Transcriptome-Wide Analysis Reveals a Role for Extracellular Matric and Integrin Receptor Genes in Otic Neurosensory Differntiation from Human iPSCs. International Journal of Molecular Sciences 2021, 22(19), 19849.
Floros VI, Pyle A, Dietmann S, Wei W, Tang WWC, Irie N, Payne B, Capalbo A, Noli L, Coxhead J, Hudson G, Crosier M, Strahl H, Khalaf Y, Saitou M, Ilic D, Surani MA, Chinnery PF. Segregation of mitochondrial DNA heteroplasmy through a developmental genetic bottleneck in human embryos. Nature Cell Biology 2018, 20, 144-151.
Thomas MG, Constantinescu CS, Sheth V, Crosier M, Patel J, Dineen RA, Maddison P, Sabbubeh T, Gottlob I. Whole Exome Sequencing Identifies a New Splicing Factor Gene Causative of X-linked Spinocerebellar Ataxia. In: Investigative Ophthalmology & Visual Science. 2015, Association for Research in Vision and Ophthalmology.
Thomas MG, Crosier M, Lindsay S, Kumar A, Araki M, Leroy BP, McLean RJ, Sheth V, Maconachie G, Thomas S, Moore AT, Gottlob I. Abnormal retinal development associated with FRMD7 mutations. Human Molecular Genetics 2014, 23(15), 4086-4093.
Kist R, Watson M, Crosier M, Robinson M, Fuchs J, Reichelt J, Peters H. The Formation of Endoderm-Derived Taste Sensory Organs Requires a Pax9-Dependent Expansion of Embryonic Taste Bud Progenitor Cells. PLoS Genetics 2014, 10(10), e1004709.
Ehrmann I, Dalgliesh C, Liu Y, Danilenko M, Crosier M, Overman L, Arthur HM, Lindsay S, Clowry GJ, Venables JP, Fort P, Elliott DJ. The Tissue-Specific RNA Binding Protein T-STAR Controls Regional Splicing Patterns of Neurexin Pre-mRNAs in the Brain. PLoS Genetics 2013, 9(4), e1003474.
Gerrelli D, Suren S, Morrison V, Cheng Y, Overman L, Crosier M, Lisgo S, Lindsay S, Copp AJ. Assisting research into human embryonic and fetal development. In: 23rd Mammalian Genetics and Development Workshop of the Genetics Society. 2012, London: Cambridge University Press.
Morris CR, Haigh S, Cuthbert G, Crosier M, Harding F, Wolstenholme J. Origin of trisomy: no evidence to support the ovarian mosaicism theory. Prenatal Diagnosis 2012, 32(7), 668-673.
Gerrelli D, Suren S, Morrison V, Cheng Y, Overman L, Crosier M, Lisgo S, Lindsay S, Copp AJ. Assisting research into human embryonic and fetal development. In: Genetics Research: 21st Mammalian Genetics and Development Workshop of the Genetics Society. 2011, London: Cambridge University Press.
Thomas MG, Crosier M, Lindsay S, Kumar A, Thomas S, Araki M, Talbot CJ, McLean RJ, Surendran M, Taylor K, Leroy BP, Moore AT, Hunter DG, Hertle RW, Tarpey P, Langmann A, Lindner S, Brandner M, Gottlob I. The clinical and molecular genetic features of idiopathic infantile periodic alternating nystagmus. Brain 2011, 134(3), 892-902.
Bakircioglu M, Carvalho OP, Khurshid M, Cox JJ, Tuysuz B, Barak T, Yilmaz S, Caglayan O, Dincer A, Nicholas AK, Quarrell O, Springell K, Karbani G, Malik S, Gannon C, Sheridan E, Crosier M, Lisgo SN, Lindsay S, Bilguvar K, Gergely F, Gunel M, Woods CG. The Essential Role of Centrosomal NDE1 in Human Cerebral Cortex Neurogenesis. American Journal of Human Genetics 2011, 88(5), 523-535.
Polster B, Crosier M, Lindsay S, Hayflick S. Expression of PLA2G6 in human fetal development: Implications for infantile neuroaxonal dystrophy. Brain Research Bulletin 2010, 83(6), 374-379.
Vega H, Trainer AH, Gordillo M, Crosier M, Kayserili H, Skovby F, Uzielli MLG, Schnur RE, Manouvrier S, Blair E, Hurst JA, Forzano F, Meins M, Simola KOJ, Raas-Rothschild A, Hennekam RCM, Jabs EW. Phenotypic variability in 49 cases of ESCO2 mutations, including novel missense and codon deletion in the acetyltransferase domain, correlates with ESCO2 expression and establishes the clinical criteria for Roberts syndrome. Journal of Medical Genetics 2010, 47(1), 30-37.
Betts-Henderson J, Bartesaghi S, Crosier M, Lindsay S, Chen HL, Salomoni P, Gottlob I, Nicotera P. The nystagmus-associated FRMD7 gene regulates neuronal outgrowth and development. Human Molecular Genetics 2010, 19(2), 342-351.
Mochida GH, Mahajnah M, Hill AD, Basel-Vanagaite L, Gleason D, Hill RS, Bodell A, Crosier M, Straussberg R, Walsh CA. A Truncating Mutation of TRAPPC9 Is Associated with Autosomal-Recessive Intellectual Disability and Postnatal Microcephaly. American Journal of Human Genetics 2009, 85(6), 897-902.
Miyake N, Chilton J, Psatha M, Cheng L, Andrews C, Chan W-M, Law K, Crosier M, Lindsay S, Cheung M, Allen J, Gutowski NJ, Ellard S, Young E, Iannaccone A, Appukuttan B, Stout JT, Christiansen S, Ciccarelli ML, Baldi A, Campioni M, Zenteno JC, Davenport D, Mariani LE, Sahin M, Guthrie S, Engle EC. Human CHN1 mutations hyperactivate α2-chimaerin and cause Duane's retraction syndrome. Science 2008, 321(5890), 839-843.
Barton S, Singh-Dang T, Greenhalgh K, Newbury-Ecob R, Crosier M, Trainer AH. Esco1, a candidate gene for TAR syndrome. In: British Human Genetics Conference. 2006, York, UK: Journal of Medical Genetics: BMJ Publishing Group.
Humphray SJ, Oliver K, Hunt AR, Plumb RW, Loveland JE, Howe KL, Andrews TD, Searle S, Hunt SE, Scott CE, Jones MC, Ainscough R, Almeida JP, Ambrose KD, Ashwell RIS, Babbage AK, Babbage S, Bagguley CL, Bailey J, Banerjee R, Barker DJ, Barlow KF, Bates K, Beasley H, Beasley O, Bird CP, Bray-Allen S, Brown AJ, Brown JY, Burford D, Burrill W, Burton J, Carder C, Carter NP, Chapman JC, Chen Y, Clarke G, Clark SY, Clee CM, Clegg S, Collier RE, Corby N, Crosier M, Cummings AT, Davies J, Dhami P, Dunn M, Dutta I, Dyer LW, Earthrowl ME, Faulkner L, Fleming CJ, Frankish A, Frankland JA, French L, Fricker DG, Garner P, Garnett J, Ghori J, Gilbert JGR, Glison C, Grafham DV, Gribble S, Griffiths C, Jones SG, Grocock R, Guy J, Hall RE, Hammond S, Harley JL, Harrison ESI, Hart EA, Heath PD, Henderson CD, Hopkins BL, Howard PJ, Howden PJ, Huckle E, Johnson C, Johnson D, Joy AA, Kay M, Keenan S, Kershaw JK, Kimberley AM, King A, Knights A, Laird GK, Langford C, Lawlor S, Leongamornlert DA, Leversha M, Lloyd C, Lloyd DM, Lovell J, Martin S, Mashreghi-Mohammadi M, Matthews L, McLaren S, McLay KE, McMurray A, Milne S, Nickerson T, Nisbett J, Nordsiek G, Pearce AV, Peck AI, Porter KM, Pandian R, Pelan S, Phillimore B, Povey S, Ramsey Y, Rand V, Scharfe M, Sehra HK, Shownkeen R, Sims SK, Skuce CD, Smith M, Steward CA, Swarbreck D, Sycamore N, Tester J, Thorpe A, Tracey A, Tromans A, Thomas DW, Wall M, Wallis JM, West AP, Whitehead SL, Willey DL, Williams SA, Wilming L, Wray PW, Young L, Ashurst JL, Coulson A, Blocker H, Durbin R, Sulston JE, Hubbard T, Jackson MJ, Bentley DR, Beck S, Rogers J, Dunham I. DNA sequence and analysis of human chromosome 9. Nature 2004, 429(6990), 369-374.
Lindsay S, Scott M, Sarma S, Woods H, Crosier M, Lisgo S, Kerwin J, Strachan T, Robson SC. Human developmental gene expression: an important link between disorder and understanding. In: Journal of Medical Genetics: British Human Genetics Conference. 2004, York, UK: BMJ Group.
Guy J, Hearn T, Crosier M, Mudge J, Viggiano L, Koczan D, Thiesen H-J, Bailey JA, Horvath JE, Eichler EE, Earthrowl ME, Deloukas P, French L, Rogers J, Bentley D, Jackson MS. Genomic sequence and transcriptional profile of the boundary between pericentromeric satellites and genes on human chromosome arm 10p. Genome Research 2003, 13(2), 159-172.
Crosier M, Viggiano L, Guy J, Misceo D, Stones R, Wei WB, Hearn T, Ventura M, Archidiacono N, Rocchi M, Jackson MS. Human paralogs of KIAA0187 were created through independent pericentromeric-directed and chromosome-specific duplication mechanisms. Genome Research 2002, 12(1), 67-80.
Crosier M, Scott D, Wilson RG, Griffiths CDM, May FEB, Westley BR. High expression of the trefoil protein TFF1 in interval breast cancers. American Journal of Pathology 2001, 159(1), 215-221.
Guy J, Spalluto C, McMurray A, Hearn T, Crosier M, Viggiano L, Miolla V, Archidiacono N, Rocchi M, Scott C, Lee PA, Sulston J, Rogers J, Bentley D, Jackson MS. Genomic sequence and transcriptional profile of the boundary between pericentrometric satellites and genes on human chromosome arm 10q. Human Molecular Genetics 2000, 9(13), 2029-2042.
Jackson MS, Rocchi M, Hearn T, Crosier M, Guy J, Viggiano L, Piccininni S, Ricco A, Marzella R, Archidiacono N, McMurray A, Sulston J, Rogers J, Bentley D, Spalluto C. Characterisation of the heterochromatin/euchromatin boundary at 10q11 and identification of novel transcripts formed by repeat induced instability. In: American Journal of Human Genetics. 1999, Cell Press.
Crosier M, Scott D, Wilson RG, Griffiths CDM, May FEB, Westley BR. Differences in Ki67 and c-erbB2 expression between screen-detected and true interval breast cancers. Clinical Cancer Research 1999, 5(10), 2682-2688.
Armour JAL, Crosier M, Jeffreys AJ. Distribution of tandem repeat polymorphism within minisatellite MS621 (D5S110). Annals of Human Genetics 1996, 60 (Pt 1), 11-20.
Armour JAL, Crosier M, Malcolm J, Chan C-T, Jeffreys AJ. Human Minisatellite Loci Composed of Interspersed GGA-GGT Triplet Repeats. Proceedings of the Royal Society B: Biological Sciences 1995, 261 (1362), 345-9.
Royle NJ, Armour JAL, Crosier M, Jeffreys AJ. Abnormal Segregation of Alleles in CEPH Pedigree DNAs Arising from Allele Loss in Lymphoblastoid DNA. Genomics 1993, 15 (1), 119-22.
Armour JAL, Monckton DG, Neil DL, Crosier M, Jeffreys AJ. Minisatellite mutation and recombination. 1993.
Armour JAL, Crosier M, Jeffreys AJ. Human minisatellite alleles detectable only after PCR amplification. Genomics 1992, 12 (1), 116-24.
Armour JAL, Vergnaud G, Crosier M, Jeffreys AJ. Isolation of human minisatellite loci detected by synthetic tandem repeat probes: Direct comparison with cloned DNA fingerprinting probes. Human Molecular Genetics 1992, 1 (5), 319-23.
Armour JAL, Crosier M, Jeffreys AJ. A highly polymorphic minisatellite (pMS626) on chromosome 13 (D13S10S). Nucleic Acids Research 1991, 19.
Crosier M, Armour JAL, Jeffreys AJ. A highly polymorphic minisatellite (pMS627) on chromosome 14 (D14S44). Nucleic Acids Research 1991, 19.
Armour JAL, Crosier M, Jeffreys AJ. A polymorphic minisatellite (pMS628) on chromosome 3 (D3S1084). Nucleic Acids Research 1991, 19.
Jeffreys AJ, Royle NJ, Patel I, Armour JAL, Crosier M. Principles and Recent Advances in Human DNA Fingerprinting. 1991.