Staff Profile

Nicola Pavese, MD, PhD, FRCP, FEAN is Professor of Clinical Neuroscience and Director of the Clinical Ageing Research Unit at Newcastle University. He is also a Consultant Neurologist at The Newcastle upon Tyne Hospitals NHS Foundation Trust. He has more than 30 years’ experience in the treatment of patients with movement disorders and his clinical activity mainly focuses on the management of patients with advanced Parkinson’s disease, Dystonia and Essential Tremor treated with Deep Brain Stimulation. 

He received his medical degree from Pisa University, Italy. After completing residency training in Neurology and subsequent training in Biochemistry and Clinical Chemistry at Pisa University, he moved to London where he achieved his PhD in Neuroimaging at Imperial College London. He had worked at the MRC Clinical Sciences Centre and Imperial College London before moving to Newcastle University.

My research involves the application of neuroimaging (Positron Emission Tomography and Magnetic Resonance Imaging) in neurodegenerative diseases to identify biomarkers of the pathological process and to elucidate the pathophysiological mechanisms responsible for the onset of specific symptoms such as dementia, depression, sleep problems, and fatigue, in patients with these conditions. My work has established for the first time that occurrence of fatigue and excessive daytime sleepiness in Parkinson’s disease are linked to definite deficits of the serotoninergic pathways in the brain which may lead to development of  new drug targets and therapeutic strategies for these disabling symptoms. I have also worked extensively in the field of neuroinflammation in neurodegenerative disorders, and I currently leads an international collaboration with Aarhus University in Denmark and Barcelona University in Spain to investigate the occurrence of neuroinflammation in subjects at high risk of developing Parkinson’s disease and other parkinsonism, including patients with REM sleep behavior disorder.

I also act as Principal Investigator in several pharmaceutical sponsored clinical trials in patients with Parkinson’s disease and other parkinsonisms.

I have published over 200 reports including original articles, reviews, book chapters, and editorials.

• Articles

  • Galgani A, Lombardo F, Frijia F, Martini N, Tognoni G, Pavese N, Giorgi FS. The degeneration of locus coeruleus occurring during Alzheimer’s disease clinical progression: a neuroimaging follow-up investigation. Brain Structure and Function 2024, 229, 1317–1325.
  • Stær K, Iranzo A, Terkelsen MH, Stokholm MGS, Danielsen EH, Østergaard K, Serradell M, Otto M, Svendsen KB, Garrido A, Vilas D, Santamaria J, Møller A, Gaig C, Brooks DJ, Borghammer P, Tolosa E, Pavese N. Progression of brain cholinergic dysfunction in patients with isolated REM sleep behaviour disorder. European Journal of Neurology 2024, 31(1), e16101.
  • Sauerbier A, Herberg J, Stopic V, Loehrer PA, Ashkan K, Rizos A, Jost ST, Petry-Schmelzer JN, Gronostay A, Schneider C, Visser-Vandewalle V, Evans J, Nimsky C, Fink GR, Antonini A, Martinez-Martin P, Silverdale M, Weintraub D, Schrag A, Ray Chaudhuri K, Timmermann L, Dafsari HS, Adler C, Bhidayasiri R, Borghammer P, Barone P, Brooks DJ, Brown R, Cantillon M, Carroll C, Coelho M, Falup-Pecurariu C, Henriksen T, Hu M, Jenner P, Jeon B, Kramberger M, Kumar P, Kurtis M, Leta V, Lewis S, Litvan I, Lyons K, Martino D, Masellis M, Mochizuki H, Morley JF, Nirenberg M, Odin P, Pagonabarraga J, Panicker J, Pavese N, Pekkonen E, Postuma R, Rodriguez Violante M, Rosales R, Schapira A, Simuni T, Stocchi F, Storch A, Subramanian I, Tagliati M, Tinazzi M, Toledo J, Tsuboi Y, Walker R. Predictors of short-term anxiety outcome in subthalamic stimulation for Parkinson’s disease. npj Parkinson's Disease 2024, 10(1), 114.
  • Pagano G, Taylor KI, Anzures Cabrera J, Simuni T, Marek K, Postuma RB, Pavese N, Stocchi F, Brockmann K, Svoboda H, Trundell D, Monnet A, Doody R, Fontoura P, Kerchner GA, Brundin P, Nikolcheva T, Bonni A, PASADENA Investigators, Prasinezumab Study Group. Prasinezumab slows motor progression in rapidly progressing early-stage Parkinson's disease. Nature Medicine 2024, 30(4), 1096-1103.
  • Staer K, Iranzo A, Stokholm MG, Hvingelby VS, Danielsen EH, Ostergaard K, Serradell M, Otto M, Svendsen KB, Garrido A, Vilas D, Santamaria J, Moller A, Gaig C, Brooks DJ, Borghammer P, Tolosa E, Pavese N. Microglial Activation and Progression of Nigrostriatal Dysfunction in Isolated REM Sleep Behavior Disorder. Movement Disorders 2024, epub ahead of print.
  • Pasquini J, Firbank MJ, Best L, Foster V, Galley D, Silani V, Ceravolo R, Petrides G, Brooks DJ, Anderson KN, Pavese N. Hypothalamic involvement in multiple system atrophy: A structural MRI study. Journal of the Neurological Sciences 2024, 460, 122985.
  • Kobylecki C, Chelban V, Goh YY, Michou E, Fumi R, TheilmannJensen M, Mohammad R, Costantini A, Vijiaratnam N, Pavey S, Pavese N, Leigh PN, Rowe JB, Hu MT, Church A, Morris HR, Houlden H. Frequency and outcomes of gastrostomy insertion in a longitudinal cohort study of atypical parkinsonism. European Journal of Neurology 2024, epub ahead of print.
  • Sigurdsson HP, Alcock L, Firbank M, Wilson R, Brown P, Maxwell R, Bennett E, Pavese N, Brooks DJ, Rochester L. Developing a novel dual-injection FDG-PET imaging methodology to study the functional neuroanatomy of gait. NeuroImage 2024, 288, 120531.
  • Stewart CB, Ledingham D, Foster VK, Anderson KN, Sathyanarayana S, Galley D, Pavese N, Pasquini J, Parkinson's Progression Markers Initiative. The longitudinal progression of autonomic dysfunction in Parkinson's disease: A 7-year study. Frontiers in Neurology 2023, 14, 1155669.
  • Andersen KB, Hansen AK, Schacht AC, Horsager J, Gottrup H, Klit H, Danielsen EH, Pavese N, Brooks DJ, Borghammer P. Synaptic Density and Glucose Consumption in Patients with Lewy Body Diseases: An [¹¹C]UCB-J and [¹⁸F]FDG PET Study. Movement Disorders 2023, 38(5), 796-805.
  • Andersen KB, Hansen AK, Schacht AC, Horsager J, Gottrup H, Klit H, Danielsen EH, Poston KL, Pavese N, Brooks DJ, Borghammer P. Synaptic Density and Glucose Consumption in Patients with Lewy Body Diseases: An [¹¹C]UCB-J and [¹⁸F]FDG PET Study. Movement Disorders 2023, 38(5), 796-805.
  • Hvingelby VS, Terkelsen MH, Valdemarsen RN, Andersen ASM, Danielsen EH, Moller M, Pavese N, Johnsen E. Prevalence and severity of freezing of gait in a Danish cohort of people with Parkinsonʼs disease. Danish Medical Journal 2023, 70(12), A03230209.
  • Galgani A, Lombardo F, Martini N, Vergallo A, Bastiani L, Hampel H, Hlavata H, Baldacci F, Tognoni G, De Marchi D, Ghicopulos I, De Cori S, Biagioni F, Busceti CL, Ceravolo R, Bonuccelli U, Chiappino D, Siciliano G, Fornai F, Pavese N, Giorgi FS. Magnetic resonance imaging Locus Coeruleus abnormality in amnestic Mild Cognitive Impairment is associated with future progression to dementia. European Journal of Neurology 2023, 30(1), 32-46.
  • Paoli D, Mills R, Brechany U, Pavese N, Nicholson C. DBS in tremor with dystonia: VIM, GPi or both? A review of the literature and considerations from a single-center experience. Journal of Neurology 2023, 270, 2217-2229.
  • Aghakhanyan G, Galgani A, Vergallo A, Lombardo F, Martini N, Baldacci F, Tognoni G, Leo A, Guidoccio F, Siciliano G, Fornai F, Pavese N, Volterrani D, Giorgi FS. Brain metabolic correlates of Locus Coeruleus degeneration in Alzheimer's disease: a multimodal neuroimaging study. Neurobiology of Aging 2023, 122, 12-21.
  • Pagano G, Taylor KI, Anzures-Cabrera J, Marchesi M, Simuni T, Marek K, Postuma RB, Pavese N, Stocchi F, Azulay JP, Mollenhauer B, López-Manzanares L, Russell DS, Boyd JT, Nicholas AP, Luquin MR, Hauser RA, Gasser T, Poewe W, Ricci B, Boulay A, Vogt A, Boess FG, Dukart J, D'Urso G, Finch R, Zanigni S, Monnet A, Pross N, Hahn A, Svoboda H, Britschgi M, Lipsmeier F, Volkova-Volkmar E, Lindemann M, Dziadek S, Holiga S, Rukina D, Kustermann T, Kerchner GA, Fontoura P, Umbricht D, Doody R, Nikolcheva T, Bonni A. Trial of Prasinezumab in Early-Stage Parkinson's Disease. New England Journal of Medicine 2022, 387, 421-432.
  • Devos D, Labreuche J, Rascol O, Corvol J-C, Duhamel A, Delannoy PG, Poewe W, Compta Y, Pavese N, Ruzicka E, Dusek P, Post B, Bloem BR, Berg D, Maetzler W, Otto M, Habert M-O, Lehericy S, Ferreira J, Dodel R, Tranchant C, Eusebio A, Thobois S, Marques A-R, Meissner WG, Ory-Magne F, Walter U, De Bie RMA, Gago M, Vilas D, Kulisevsky J, Januario C, Coelho MVS, Behnke S, Worth P, Seppi K, Ouk T, Potey C, Leclercq C, Viard R, Kuchcinski G, Lopes R, Pruvo J-P, Pigny P, Garcon G, Simonin O, Carpentier J, Rolland A-S, Nyholm D, Scherfler C, Mangin J-F, Chupin M, Bordet R, Dexter DT, Fradette C, Spino M, Tricta F, Ayton S, Bush AI, Devedjian J-C, Duce JA, Cabantchik I, Defebvre L, Deplanque D, Moreau C. Trial of Deferiprone in Parkinson's Disease. New England Journal of Medicine 2022, 387(22), 2045-2055.
  • Jesuthasan A, Garcia LR, Pavese N. Studying cognitive function in patients with a long-standing diagnosis of SWEDD. Journal of the Neurological Sciences 2022, 441, 120353.
  • Zhang Z, Jiang R, Zhang C, Williams B, Jiang Z, Li C, Chazot P, Pavese N, Bouridane A, Beghdadi A. Robust Brain Age Estimation based on sMRI via Nonlinear Age-Adaptive Ensemble Learning. IEEE Transactions on Neural Systems and Rehabilitation Engineering 2022, 30, 2146-2156.
  • Jiang R, Chazot P, Pavese N, Crookes D, Bouridane A, Celebi ME. Private Facial Prediagnosis as an Edge Service for Parkinson's DBS Treatment Valuation. IEEE Journal of Biomedical and Health Informatics 2022, 26(6), 2703-2713.
  • Schofield C, Chaudhuri KR, Carroll C, Sharma JC, Pavese N, Evans J, Foltynie T, Reichmann H, Zurowska L, Soares-Da-Silva P, Lees A. Opicapone in UK clinical practice: effectiveness, safety and cost analysis in patients with Parkinson's disease. Neurodegenerative Disease Management 2022, 12(2), 77-91.
  • Xing Y, Sapuan AH, Martin-Bastida A, Naidu S, Tench C, Evans J, Sare G, Schwarz ST, Al-bachari S, Parkes LM, Kanavou S, Raw J, Silverdale M, Bajaj N, Pavese N, Burn D, Piccini P, Grosset DG, Auer DP. Neuromelanin-MRI to Quantify and Track Nigral Depigmentation in Parkinson's Disease: A Multicenter Longitudinal Study Using Template-Based Standardized Analysis. Movement Disorders 2022, 37(5), 1028-1039.
  • Chelban V, Nikram E, Perez-Soriano A, Wilke C, Foubert-Samier A, Vijiaratnam N, Guo T, Jabbari E, Olufodun S, Gonzalez M, Senkevich K, Laurens B, Peran P, Rascol O, Le Traon AP, Todd EG, Costantini AA, Alikhwan S, Tariq A, Ng BL, Munoz E, Painous C, Compta Y, Junque C, Segura B, Zhelcheska K, Wellington H, Schols L, Jaunmuktane Z, Kobylecki C, Church A, Hu MTM, Rowe JB, Leigh PN, Massey L, Burn DJ, Pavese N, Foltynie T, Pchelina S, Wood N, Heslegrave AJ, Zetterberg H, Bocchetta M, Rohrer JD, Marti MJ, Synofzik M, Morris HR, Meissner WG, Houlden H. Neurofilament light levels predict clinical progression and death in multiple system atrophy. Brain 2022, 145(12), 4398-4408.
  • Horsager J, Okkels N, Hansen AK, Damholdt MF, Andersen KH, Fedorova TD, Munk OL, Danielsen EH, Pavese N, Brooks DJ, Borghammer P. Mapping Cholinergic Synaptic Loss in Parkinson's Disease: An [¹⁸F]FEOBV PET Case-Control Study. Journal of Parkinson's Disease 2022, 12(8), 2493-2506.
  • Giorgi FS, Martini N, Lombardo F, Galgani A, Bastiani L, Della Latta D, Hlavata H, Busceti CL, Biagioni F, Puglisi-Allegra S, Pavese N, Fornai F. Locus Coeruleus magnetic resonance imaging: a comparison between native-space and template-space approach. Journal of Neural Transmission 2022, 129, 387-394.
  • Giorgi FS, Lombardo F, Galgani A, Hlavata H, Della Latta D, Martini N, Pavese N, Ghicopulos I, Baldacci F, Coi A, Scalese M, Bastiani L, Keilberg P, De Marchi D, Fornai F, Bonuccelli U. Locus Coeruleus magnetic resonance imaging in cognitively intact elderly subjects. Brain Imaging and Behavior 2022, 16, 1077-1087.
  • Sigurdsson HP, Yarnall AJ, Galna B, Lord S, Alcock L, Lawson RA, Colloby SJ, Firbank MJ, Taylor JP, Pavese N, Brooks DJ, O'Brien JT, Burn DJ, Rochester L. Gait-related metabolic covariance networks at rest in Parkinson’s disease. Movement Disorders 2022, 37(6), 1222-1234.
  • Galgani A, Vergallo A, Campese N, Lombardo F, Pavese N, Petrozzi L, LoGerfo A, Franzini M, Cecchetti D, Puglisi-Allegra S, Busceti CL, Siciliano G, Tognoni G, Baldacci F, Lista S, Hampel H, Fornai F, Giorgi FS. Biological determinants of blood-based cytokines in the Alzheimer's disease clinical continuum. Journal of Neurochemistry 2022, 163(1), 40-52.
  • Xu Z, Anderson KN, Saffari SE, Lawson RA, Chaudhuri KR, Brooks David, Pavese N. Progression of sleep disturbances in Parkinson’s Disease. A 5-year longitudinal study. Journal of Neurology 2021, 268, 312-320.
  • Kinnerup MB, Sommerauer M, Damholdt FM, Schaldemose JL, Ismail R, Terkelsen AJ, Stær K, Hansen A, Fedorova TD, Knudsen K, Skjærbæk C, Borghammer P, Pavese N, Brooks DJ, Nahimi A. Preserved noradrenergic function in Parkinson´s disease patients with rest tremor. Neurobiology of Disease 2021, 152, 105295.
  • Farmen K, Nissen SK, Stokholm MG, Iranzo A, Østergaard K, Serradell M, Otto M, Svendsen KB, Garrido A, Vilas D, Borghammer P, Santamaria J, Møller A, Gaig C, Brooks DJ, Tolosa E, Pavese N, Romero-Ramos M. Monocyte markers correlate with immune and neuronal brain changes in REM Sleep Behaviour Disorder. Proceedings of the National Academy of Sciences of the United States of America 2021, 118(10), e2020858118.
  • Pagano G, Molloy S, Bain PG, Rabiner EA, Chaudhuri KR, Brooks DJ, Pavere N. Impulse control disorders are associated with lower ventral striatum dopamine D3 receptor availability in Parkinson's disease: a [¹¹C]-PHNO PET study. Parkinsonism & Related Disorders 2021, 90, 52-56.
  • Eskildsen SF, Iranzo A, Stokholm MG, Stær K, Østergaard K, Serradell M, Otto M, Svendsen KB, Garrido A, Vilas D, Borghammer P, Santamaria J, Møller A, Gaig C, Brooks DJ, Tolosa E, Østergaard L, Pavese N. Impaired cerebral microcirculation in isolated rapid eye movement sleep behaviour disorder. Brain 2021, 144(5), 1498-1508.
  • Mullin S, Stokholm MG, Hughes D, Mehta A, Parbo P, Hinz R, Pavese N, Brooks DJ, Schapira AHV. Brain microglial activation increased in glucocerebrosidase (GBA1) mutation carriers. Movement Disorders 2021, 36(3), 774-779.
  • Lang AE, Stebbins GT, Wang P, Jabbari E, Lamb R, Morris H, Boxer AL, Boxer (PI) A, Boeve B, Dickerson B, Grossman M, Litvan I, Ljubenkov P, Pantelyat A, Rojas-Martinez J, Tartaglia M-C, Wills A-M, Morris (PI) H, Amar K, Capps E, Carey G, Church A, Critchley P, Ghosh B, Houlden H, Hu M, Kobylecki C, Massey L, Molloy S, Nath U, Pavese N, Rowe JB. The Cortical Basal ganglia Functional Scale (CBFS): Development and preliminary validation. Parkinsonism and Related Disorders 2020, 79, 121-126.
  • Stokholm MG, Garrido A, Tolosa E, Serradell M, Iranzo A, Østergaard K, Borghammer P, Møller A, Parbo P, Stær K, Brooks DJ, Martí MJ, Pavese N. Imaging dopamine function and microglia in asymptomatic LRRK2 mutation carriers. Journal of Neurology 2020, 267, 2296-2300.
  • Palermo G, Giannoni S, Frosini D, Morganti R, Volterrani D, Bonuccelli U, Pavese N, Ceravolo R. Dopamine Transporter, Age, and Motor Complications in Parkinson's Disease: A Clinical and Single-Photon Emission Computed Tomography Study. Movement Disorders 2020, 35(6), 1028-1036.
  • Jabbari E, Holland N, Chelban V, Jones PS, Lamb R, Rawlinson C, Guo T, Costantini AA, Tan MMX, Heslegrave AJ, Roncaroli F, Klein JC, Ansorge O, Allinson KSJ, Jaunmuktane Z, Holton JL, Revesz T, Warner TT, Lees AJ, Zetterberg H, Russell LL, Bocchetta M, Rohrer JD, Williams NM, Grosset DG, Burn DJ, Pavese N, Gerhard A, Kobylecki C, Leigh PN, Church A, Hu MTM, Woodside J, Houlden H, Rowe JB, Morris HR. Diagnosis across the Spectrum of Progressive Supranuclear Palsy and Corticobasal Syndrome. JAMA Neurology 2020, 77(3), 377-387.
  • Gersel Stokholm M, Iranzo A, Ostergaard K, Serradell M, Otto M, Bacher Svendsen K, Garrido A, Vilas D, Fedorova TD, Santamaria J, Moller A, Gaig C, Hiraoka K, Brooks DJ, Okamura N, Borghammer P, Tolosa E, Pavese N. Cholinergic denervation in patients with idiopathic rapid eye movement sleep behaviour disorder. European Journal of Neurology 2020, 27(4), 644-652.
  • Horsager J, Andersen KB, Knudsen K, Skjærbæk C, Fedorova TD, Okkels N, Schaeffer E, Bonkat SK, Geday J, Otto M, Sommerauer M, Danielsen EH, Bech E, Kraft J, Munk OL, Hansen SD, Pavese N, Göder R, Brooks DJ, Berg D, Borghammer P. Brain-first vs. Body-first Parkinson’s disease: a multi-modal imaging case-control study. Brain 2020, 143(10), 3077-3088.
  • Horsager J, Andersen KB, Knudsen K, Skjaerbaek C, Fedorova TD, Okkels N, Schaeffer E, Bonkat SK, Geday J, Otto M, Sommerauer M, Danielsen EH, Bech E, Kraft J, Munk OL, Hansen SD, Pavese N, Goder R, Brooks DJ, Berg D, Borghammer P. Brain-first versus body-first Parkinson's disease: a multimodal imaging case-control study. Brain 2020, 143(10), 3077-3088.
  • Andersen K, Hansen AK, Sommerauer M, Fedorova TD, Knudsen K, Vang K, VanDenBerge N, Kinnerup M, Nahimi A, Pavese N, Brooks DJ, Borghammer P. Altered sensorimotor cortex noradrenergic function in idiopathic REM sleep behaviour disorder – a PET study. Parkinsonism & Related Disorders 2020, 75, 63-69.
  • Jabbari E, Woodside J, Tan MMX, Pavese N, Bandmann O, Ghosh BCP, Massey LA, Capps E, Warner TT, Lees AJ, Revesz T, Holton JL, Williams NM, Grosset DG, Morris HR. The genetic and clinico-pathological profile of early-onset progressive supranuclear palsy. Movement Disorders 2019, 34(9), 1307-1314.
  • Tilley BS, Smith C, Pavese N, Attems J. Rare histotype of sporadic Creutzfeldt-Jakob disease, clinically suspected as corticobasal degeneration. BMJ Case Reports 2019, 12(3), e228305.
  • Pasquini J, Ceravolo R, Brooks DJ, Bonuccelli U, Pavese N. Progressive loss of raphe nuclei serotonin transporter in early Parkinson’s disease: a longitudinal ¹²³I-FP-CIT SPECT study. Parkinsonism & Related Disorders 2019, 77, 170-175.
  • Durcan R, Wiblin L, Lawson RA, Khoo TK, Yarnall AJ, Duncan GW, Brooks DJ, Pavese N, Burn DJ. Prevalence and duration of non‐motor symptoms in prodromal Parkinson's disease. European Journal of Neurology 2019, 26(7), 979-985.
  • van Eimeren T, Antonini A, Berg D, Bohnen N, Ceravolo R, Drzezga A, Hoglinger GU, Higuchi M, Lehericy S, Lewis S, Monchi O, Nestor P, Ondrus M, Pavese N, Peralta MC, Piccini P, Pineda-Pardo JA, Rektorova I, Rodriguez-Oroz M, Rominger A, Seppi K, Stoessl AJ, Tessitore A, Thobois S, Kaasinen V, Wenning G, Siebner HR, Strafella AP, Rowe JB. Neuroimaging biomarkers for clinical trials in atypical parkinsonian disorders: Proposal for a Neuroimaging Biomarker Utility System. Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring 2019, 11, 301-309.
  • Pasquini J, Durcan R, Wiblin L, Stokholm MG, Lynn Rochester L, Brooks DJ, Burn D, Pavese N. Clinical implications of early caudate dysfunction in Parkinson’s disease. Journal of Neurology, Neurosurgery & Psychiatry 2019, 90(10), 1098-1104.
  • Pasquini J, Ceravolo R, Qamhawi Z, Lee JY, Deuschl G, Brooks DJ, Bonuccelli U, Pavese N. Progression of tremor in early stages of Parkinson’s disease: a clinical and neuroimaging study . Brain 2018, 141(3), 811-821.
  • Xu Z, Arbizu J, Pavese N. PET Molecular Imaging in Atypical Parkinsonism. International Review of Neurobiology 2018, 142, 3-36.
  • Lee JY, Lao-Kaim NP, Pasquini J, Deuschl G, Pavese N, Piccini P. Pallidal dopaminergic denervation and rest tremor in early Parkinson’s disease: PPMI cohort analysis. Parkinsonism & Related Disorders 2018, 51, 101-104.
  • Maxan A, Mason S, Saint-Pierre M, Smith E, Ho A, Harrower T, Watts C, Tai Y, Pavese N, Savage JC, Tremblay ME, Gould P, Rosser AE, Dunnett SB, Piccini P, Barker RA, Cicchetti F. Outcome of cell suspension allografts in a patient with Huntington’s disease. Annals of Neurology 2018, 84(6), 950-956.
  • Knudsen K, Fedorova TD, Hansen AK, Sommerauer M, Otto M, Svendsen KB, Nahimi A, Stokholm MG, Pavese N, Beier CP, Brooks DJ, Borghammer P. In vivo staging of pathology in REM Sleep Behaviour Disorder – a multi-modality imaging case-control study. Lancet Neurology 2018, 17(7), 618-628.
  • Strafella AP, Bohnen NI, Pavese N, Vaillancourt DE, van Eimeren T, Politis M, Tessitore A, Ghadery C, Lewis S. Imaging Markers of Progression in Parkinson's Disease. Movement Disorders Clinical Practice 2018, 5(6), 567-663.
  • Stokholm MG, Iranzo A, Østergaard K, Serradell M, Otto M, Svendsen KB, Garrido A, Vilas D, Parbo P, Borghammer P, Santamaria J, Møller A, Gaig C, Brooks DJ, Tolosa E, Pavese N. Extrastriatal monoaminergic dysfunction and enhanced microglial activation in idiopathic rapid eye movement sleep behaviour disorder. Neurobiology of Disease 2018, 115, 9-16.
  • Woitalla D, Dunac A, Safavi A, Ceravolo MG, Gomez Esteban JC, Pavese N, Asgharnejad M, Joeres L, Schuller JC, Chaudhuri KR. A noninterventional study evaluating the effectiveness of rotigotine and levodopa combination therapy in younger versus older patients with Parkinson's disease. Expert Opinion on Pharmacotherapy 2018, 19(9), 937-945.
  • Politis M, Sauerbier A, Loane C, Pavese N, Martin A, Corcoran B, Brooks DJ, Ray-Chaudhuri K, Piccini P. Sustained striatal dopamine levels following intestinal levodopa infusions in Parkinson's disease patients. Movement Disorders 2017, 32(2), 235-240.
  • Parbo P, Ismail R, Hansen K, Mårup F, Gottrup H, Braendgaard H, Eriksson B, Eskildsen S, Lund T, Tietze A, Edison P, Pavese N, Stokholm M, Borghammer P, Hinz R, Aanerud J, Brooks DJ. Brain inflammation accompanies amyloid in a majority of mild cognitive impairment cases due to Alzheimer’s disease. Brain 2017, 140(7), 2002-2011.
  • Arshad Q, Bonsu A, Lobo R, Fluri A-S, Sheriff R, Bain P, Pavese N, Bronstein AM. Biased numerical cognition impairs economic decision-making in Parkinson's disease. Annals of Clinical and Translational Neurology 2017, 739-748.
  • Stokholm MG, Iranzo A, Ostergaard K, Serradell M, Otto M, Svendsen KB, Garrido A, Vilas D, Borghammer P, Santamaria J, Moller A, Gaig C, Brooks DJ, Tolosa E, Pavese N. Assessment of neuroinflammation in patients with idiopathic rapid-eye-movement sleep behaviour disorder: A case-control study. The Lancet Neurology 2017, 16(10), 789-796.
  • Pagano G, Molloy S, Bain PG, Rabiner EA, Chaudhuri KR, Brooks DJ, Pavese N. Sleep problems and hypothalamic dopamine D3 receptor availability in Parkinson disease. Neurology 2016, 87(23), 2451-2456.
  • Weintraub D, Simuni T, Caspell-Garcia C, Coffey C, Lasch S, Siderowf A, Aarsland D, Barone P, Burn D, Chahine LM, Eberling J, Espay AJ, Foster ED, Leverenz JB, Litvan I, Richard I, Troyer MD, Hawkins KA, Marek K, Jennings D, Tanner C, Kieburtz K, Poewe W, Mollenhauer B, Foroud T, Galasko D, Sherer T, Chowdhury S, Frasier M, Kopil C, Arnedo V, Rudolph A, Seibyl J, Mendick S, Schuff N, Caspell C, Uribe L, Foster E, Gloer K, Yankey J, Toga A, Berlin D, Casalin P, Malferrari G, Trojanowski J, Shaw L, Russell D, Factor S, Hogarth P, Standaert D, Hauser R, Jankovic J, Stern M, Chahine L, Frank S, Seppi K, Shill H, Berg D, Mari Z, Pavese N, Espay A, Devoto J, Rowe D, Brandabur M, Alcalay R, Tolosa E, York M, Leary L, Riordan C, Rees L, Portillo A, Lenahan A, Williams K, Guthrie S, Rawlins A, Harlan S, Hunter C, Tran B, Thomas C-A, James R, Sprenger F, Willeke D, Obradov S, Mule J, Gauss K, Fontaine D, Shah B, Ranola M, Sims JR. Cognitive Performance and Neuropsychiatric Symptoms in Early, Untreated Parkinson's Disease. Movement Disorders 2015, 30(7), 919-927.
  • Grover VPB, Pavese N, Koh SB, Wylezinska M, Saxby BK, Gerhard A, Forton DM, Brooks DJ, Thomas HC, Taylor-Robinson SD. Cerebral microglial activation in patients with hepatitis c: in vivo evidence of neuroinflammation. Journal of Viral Hepatitis 2012, 19(2), E89-E96.

• Conference Proceedings (inc. Abstracts)

  • Angeles P, Tai Y, Pavese N, Wilson S, Vaidyanathan R. Automated assessment of symptom severity changes during deep brain stimulation (DBS) therapy for Parkinson's disease. In: IEEE International Conference on Rehabilitation Robotics (ICORR). 2017, London, UK: IEEE Computer Society.
  • Simpson B, Pavese N, Ramlackhansingh A, Breen D, Barker R, Burn D, Brooks D. Clinical and Cognitive Correlates of Brain Inflammation in Parkinson Disease: A PET Study. In: NEUROLOGY. 2013, 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA: LIPPINCOTT WILLIAMS & WILKINS.

• Editorial

  • Pavese N. Is neuromelanin the imaging biomarker for the early diagnosis of Parkinson's disease that we were looking for?. Parkinsonism & Related Disorders 2019, 58, 1-2.

• Letter

  • Pasquini J, Pavese N. Striatal dopaminergic denervation and hypomimia in Parkinson's disease. European Journal of Neurology 2021, 28(1), e2-e3.

• Notes

  • Stewart CB, Ledingham D, Foster VK, Anderson KN, Sathyanarayana S, Galley D, Pavese N, Pasquini J. Corrigendum: The longitudinal progression of autonomic dysfunction in Parkinson's disease: a 7-year study (Front. Neurol., (2023), 14, 1155669, 10.3389/fneur.2023.1155669). Frontiers in Neurology 2023, 14, 1218633.
  • Dam T, Boxer AL, Golbe LI, Hoglinger GU, Morris HR, Litvan I, Lang AE, Corvol J-C, Aiba I, Grundman M, Yang L, Tidemann-Miller B, Kupferman J, Harper K, Kamisoglu K, Wald MJ, Graham DL, Gedney L, O'Gorman J, Haeberlein SB, Aiba I, Antonini A, Apetauerova D, Azulay J-P, Martinez EB, Bang J, Barone P, Barrett M, Bega D, Berg D, Corrales KB, Bordelon Y, Boxer AL, Brandt M, Brueggemann N, Castelnovo G, Ceravolo R, Chuang R, Chung SJ, Church A, Corvol J-C, Cudia P, Dale M, Defebvre L, Drapier S, Driver-Dunckley ED, Ebersbach G, Eggert KM, Ellenbogen A, Eusebio A, Evans AH, Fedorova N, Finger E, Foubert-Samier A, Ghosh B, Golbe L, Perez FG, Grossman M, Hall D, Hamada K, Hasegawa K, Hoeglinger G, Honig L, Houghton D, Huang X, Isaacson S, Koh SB, Bojarski JK, Lang AE, Leigh PN, Litvan I, Lozano JJL, Moreno JLL-S, Ludolph AC, Piudo MRL, Torres IM, McFarland N, Meissner W, Mestre T, Rivera PM, Molho E, Mollenhauer B, Morris HR, Murata M, Obi T, Magne FO, O'Suilleabhain P, Pahwa R, Pantelyat A, Pavese N, Pokhabov D, Prudlo J, Rodriguez-Porcel F, Rowe J, Savitt J, Schnitzler A, Schulz JB, Seppi K, Shah B, Shill H, Shprecher D, Stamelou M, Steiger M, Takahashi Y, Takigawa H, Tartaglia C, Toenges L, Truong D, Tse W, Tuite P, Volc D, Wills A-MA, Woitalla D, Xie T, Yuasa T, Zauber SE, Zesiewicz T. Author Correction: Safety and efficacy of anti-tau monoclonal antibody gosuranemab in progressive supranuclear palsy: a phase 2, randomized, placebo-controlled trial (Nature Medicine, (2021), 27, 8, (1451-1457), 10.1038/s41591-021-01455-x). Nature Medicine 2022, correction - authors.
  • Pavese N. Atypical Parkinsonian Syndromes and Subtypes of Parkinson's Disease. Will a Single Neuroimaging Modality Ever Be Enough?. Movement Disorders Clinical Practice 2021, 8(2), 172-174.

• Reviews

  • Ledingham D, Baker M, Pavese N. Local field potentials: Therapeutic implications for DBS in dystonia including adaptive DBS for dystonia. Deep Brain Stimulation 2024, 5, 4-19.
  • Hvingelby V, Carra RB, Hamani C, Krauss JK, Moro E, Pavese N, Cury RG, AlDakheel A, Alexoudi A, Bloem BR, Blahak C, Butson C, Capato T, Capato T, Chabardes S, Coyne TJ, Cury R, Debu B, Foltynie T, Fonoff E, Foote K, Fraix V, Grabli D, Gulberti A, Haas A, Hamani C, Hirsch E, Terkelsen MH, Terkelsen MH, Horak F, Hutchison W, Hvingelby V, Joint C, Kalia S, Kang U, Kosutzka Z, Kosutzka Z, Luca C, Mazzone P, Ostrem J, Okun MS, Pavese N, Potter-Nerger M, Prakash N, Safarpour D, Sarangmat N, Schrader C, Silburn PA, Sorensen JCH, Stefani A, Stein J, Tai C-H, Tai Y, Thevathasan W, Veletzas I, Wagner J, Welter M-L, Zrinzo L. A Pragmatic Review on Spinal Cord Stimulation Therapy for Parkinson's Disease Gait Related Disorders: Gaps and Controversies. Movement Disorders Clinical Practice 2024, epub ahead of print.
  • Xu Z, Anderson KN, Pavese N. Longitudinal Studies of Sleep Disturbances in Parkinson’s Disease. Current Neurology and Neuroscience Reports 2022, 22, 635-655.
  • Hvingelby VS, Glud AN, Sorensen JCH, Tai Y, Andersen ASM, Johnsen E, Moro E, Pavese N. Interventions to improve gait in Parkinson’s disease: a systematic review of randomized controlled trials and network meta-analysis. Journal of Neurology 2022, 269, 4068-4079.
  • Cury RG, Pavese N, Aziz TZ, Krauss JK, Moro E. Gaps and roadmap of novel neuromodulation targets for treatment of gait in Parkinson’s disease. npj Parkinson's Disease 2022, 8(1), 8.
  • Pasquini J, Firbank MJ, Ceravolo R, Silani V, Pavese N. Diffusion Magnetic Resonance Imaging Microstructural Abnormalities in Multiple System Atrophy: A Comprehensive Review. Movement Disorders 2022, 37(10), 1963-1984.
  • Pasquini J, Brooks DJ, Pavese N. The Cholinergic Brain in Parkinson's Disease. Movement Disorders Clinical Practice 2021, 8(7), 1012-1026.
  • Bellini G, Best LA, Brechany U, Mills R, Pavese N. Clinical Impact of Deep Brain Stimulation on the Autonomic System in Patients with Parkinson's Disease. Movement Disorders Clinical Practice 2020, 7(4), 373-382.
  • Ghadery C, Best LA, Pavese N, Tai YF, Strafella AP. PET Evaluation of Microglial Activation in Non-neurodegenerative Brain Diseases. Current Neurology and Neuroscience Reports 2019, 19(7), 38.
  • Best L, Ghadery C, Pavese N, Tai YF, Strafella AP. New and Old TSPO PET Radioligands for Imaging Brain Microglial Activation in Neurodegenerative Disease. Current Neurology and Neuroscience Reports 2019, 19(5), 24.
  • Thevathasan W, Debu B, Aziz T, Bloem BR, Blahak C, Butson C, Czernecki V, Foltynie T, Fraix V, Grabli D, Joint C, Lozano AM, Okun MS, Ostrem J, Pavese N, Schrader C, Tai C-H, Krauss JK, Moro E. Pedunculopontine nucleus deep brain stimulation in Parkinson's disease: A clinical review. Movement Disorders 2018, 33(1), 10-20.
  • Pavese N, Tai YF. Nigrosome imaging and neuromelanin sensitive MRI in diagnostic evaluation of parkinsonism. Movement Disorders Clinical Practice 2018, 5(2), 131-140.
  • Strafella AP, Bohnen NI, Perlmutter JS, Eidelberg D, Pavese N, Van Eimeren T, Piccini P, Politis M, Thobois S, Ceravolo R, Higuchi M, Kaasinen V, Masellis M, Peralta MC, Obeso I, Pineda-Pardo JA, Cilia R, Ballanger B, Niethammer M, Stoessl JA. Molecular imaging to track Parkinson's disease and atypical parkinsonisms: New imaging frontiers. Movement Disorders 2017, 32(2), 181-192.