Staff Profile
Ruth Wood
Data Manager
- Address: Newcastle Clinical Trials Unit
Baddiley-Clark Building,
Newcastle University,
Richardson Road,
Newcastle upon Tyne,
NE2 4AX
Introduction
I have worked with databases and data at Newcastle University since 1993, during that time I have worked on many projects in diverse clinical areas, from stroke disease to various clinical and surgical trials. I have extensive knowledge of Microsoft Access and have developed many applications to administer and collect research data. With the introduction of the EU Directive I have become familiar with other databases which fulfil the relevant regulations. In NCTU we are currently using Ennov's MACRO and Sealed Envelope’s Red Pill clinical data management systems to collect research data for clinical trials.
I have extensive experience of using both SPSS and MS Access for data cleaning activities and statistical analyses.
Roles and Responsibilities
As a Data Manager I am currently working on a number of trials, including;
- CaPP3 trial - Cancer Prevention Programme
- Haplo+4Kids trial - Memory T-cells to improve immunity after TCRαβ/CD19 depleted haploidentical donor stem cell transplantation for inborn errors of immunity
- MultICath trial - A non-inferiority randomised controlled trial to compare mixed (multi/single-use) catheter management with single-use catheter management by intermittent catheter users over 12 months
Qualifications
BSc (Hons) Psychology & Zoology (University of Reading)
T.E.C. Higher Certificate in Computer Technology and Electronics (Middlesex Polytechnic)
MSc Management of Information Technology (Part time Sunderland University)
Research Interests
Data and information management and analyses, clinical trials methodology.
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Articles
- Wyatt NJ, Watson H, Anderson CA, Kennedy NA, Raine T, Ahmad T, Allerton D, Bardgett M, Clark E, Clewes D, Martin CC, Doona M, Doyle JA, Frith K, Hancock H, Hart A, Hildreth V, Irving PM, Iqbal S, Kennedy C, King A, Lawrence S, Lees CW, Lees R, Letchford L, Liddle T, Lindsay JO, Maier RH, Mansfield JC, Marchesi JR, McGregor N, McIntyre RE, Ostermayer J, Osunnuyi T, Powell N, Prescott NJ, Satsangi J, Sharma S, Shrestha T, Speight A, Strickland M, Wason JMS, Whelan K, Wood R, Young GR, Zhang X, Parkes M, Stewart CJ, Jostins-Dean L, Lamb CA. Defining predictors of responsiveness to advanced therapies in Crohn’s disease and ulcerative colitis: Protocol for the IBD-RESPONSE and nested CD-metaRESPONSE prospective, multicentre, observational cohort study in precision medicine. BMJ Open 2024, 14(4).
- Gravestock P, Clark E, Morton M, Sharma S, Fisher H, Walker J, Wood R, Hancock H, Waugh N, Cooper A, Maier R, Marshall J, Chandler R, Bahl A, Crabb S, Jain S, Pedley I, Jones R, Staffurth J, Heer R. Using the AR-V7 biomarker to determine treatment in metastatic castrate resistant prostate cancer, a feasibility randomised control trial, conclusions from the VARIANT trial. NIHR Open Research 2023, 2, 49.
- Lambert H, Hiu S, Coulthard MG, Matthews JNS, Holstein E-M, Crosier J, Agbeko R, Brick T, Duncan H, Grant D, Mok Q, Nyman AG, Pappachan J, Boucher C, Bulmer J, Chisholm D, Cromie K, Emmet V, Feltbower RG, Ghose A, Grayling M, Harrison R, Kennedy CA, Mccoll E, Morris K, Norman L, Office J, Parslow R, Pattinson C, Sharma S, Smith J, Steel A, Steel R, Straker J, Vrana L, Walker J, Wellman P, Whitaker M, Wightman J, Wilson N, Wirz L, Wood R. The Infant KIdney Dialysis and Utrafiltration (I-KID) Study: A Stepped-Wedge Cluster-Randomized Study in Infants, Comparing Peritoneal Dialysis, Continuous Venovenous Hemofiltration, and Newcastle Infant Dialysis Ultrafiltration System, a Novel Infant Hemodialysis Device. Pediatric Critical Care Medicine 2023, 24(7), 604-613.
- Wood CL, Morrison N, Cole M, Donaldson M, Dunger DB, Wood R, Pearce SHS, Cheetham TD, Mayo A, Oxley C, Kirk J, Barrett T, Acerini C, Gregory J, Warner J, Stirling H, Greene S, Drake A, Shaikh G, Gault E-J, Staines J, Blair J, Dharmaraj P, Banerjee I, Ehtisham S, Johnstone H, Matthews D, Owen K, Thalange N, Dimitri P, Wright N, Wales J, Albanese A, Bain M. Initial response of young people with thyrotoxicosis to block and replace or dose titration thionamide. European Thyroid Journal 2022, 11(1), e210043.
- Bourke JP, Watson G, Spinty S, Bryant A, Roper H, Chadwick T, Wood R, Mccoll E, Bushby K, Muntoni F, Guglieri M. Preventing Cardiomyopathy in DMD. Neurology: Clinical Practice 2021, 11(5), E661-E668.
- Wilson JA, Stocken DD, Watson GC, Fouweather T, McGlashan J, MacKenzie K, Carding P, Karagama Y, Harries M, Ball S, Khwaja S, Costello D, Wood R, Lecouturier J, O'Hara J. Lansoprazole for persistent throat symptoms in secondary care: the TOPPITS RCT. Health Technology Assessment 2021, 25(3), 1-118.
- White P, Gregson B, McColl E, Brennan P, Steel A, Watts P, Wood R, Bowes C, Javadpour M, Weston A, Mitra D. Emergent aneurysm treatment compared with treatment on neurological improvement in patients with ruptured poor-grade aneurysmal subarachnoid haemorrhage: the TOPSAT2 RCT. Efficacy and Mechanism Evaluation 2021, 8(8).
- Grahame V, Dixon L, Fletcher-Watson S, Garland D, Glod M, Goodwin J, Grayson Z, Heron S, Honey E, Iversen R, Kasim AS, Kernohan A, Kharatikoopaei E, Le Couteur A, Mackie L, Mathias A, Probert H, Riby D, Rob P, Rogan L, Thompson S, Vale L, Walls E, Webb EI, Weetman C, Wolstenhulme F, Wood R, Rodgers J. A clinical and cost-effectiveness trial of a parent group intervention to manage challenging restricted and repetitive behaviours in young children with autism spectrum disorder: study protocol for a randomised controlled trial. Trials 2021, 22(1), 240.
- Wood CL, Cole M, Donaldson M, Dunger DB, Wood R, Morrison N, Matthews JNS, Pearce SHS, Cheetham TD. Randomised trial of block and replace vs dose titration thionamide in young people with thyrotoxicosis. European Journal of Endocrinology 2020, 183(6), 637-645.
- Liew A, Holmes-Truscott E, Flatt AJS, Bennett D, Crookston R, Pimkova M, Birtles L, Casey J, Pernet A, Wood RC, Choudhary P, Forbes S, Rutter MK, Rosenthal M, Johnson P, Shaw JAM, Speight J. Characterization of pre-transplant psychosocial burden in an integrated national islet transplant program. Islets 2020, 12(2), 21-31.
- Clark E, Morton M, Sharma S, Fisher H, Howel D, Walker J, Wood R, Hancock H, Maier R, Marshall J, Bahl A, Crabb S, Jain S, Pedley I, Jones R, Staffurth J, Heer R. Prostate cancer androgen receptor splice variant 7 biomarker study - A multicentre randomised feasibility trial of biomarker-guided personalised treatment in patients with advanced prostate cancer (the VARIANT trial) study protocol. BMJ Open 2019, 9(12), e034708.
- Flatt AJS, Little SA, Speight J, Leelarathna L, Walkinshaw E, Tan HK, Bowes A, Lubina-Solomon A, Holmes-Truscott E, Chadwick TJ, Wood R, McDonald TJ, Kerr D, Flanagan D, Brooks A, Heller SR, Evans ML, Shaw JAM. Predictors of Recurrent Severe Hypoglycemia in Adults With Type 1 Diabetes and Impaired Awareness of Hypoglycemia During the HypoCOMPaSS Study. Diabetes Care 2019, 42(10), 1-9.
- Bourke JP, Watson G, Muntoni F, Spinty S, Roper H, Guglieri M, Speed C, McColl E, Chikermane A, Jayawant S, Adwani S, Willis T, Wilkinson J, Bryant A, Chadwick T, Wood R, Bushby K. Randomised placebo-controlled trial of combination ACE inhibitor and beta-blocker therapy to prevent cardiomyopathy in children with Duchenne muscular dystrophy? (DMD Heart Protection Study): a protocol study. BMJ open 2018, 8(12), e022572-.
- Wright SE, Thomas K, Watson G, Baker C, Bryant A, Chadwick TJ, Shen J, Wood R, Wilkinson J, Mansfield L, Stafford V, Wade C, Furneval J, Henderson A, Hugill K, Howard P, Roy A, Bonner S, Baudouin S. Intensive versus standard physical rehabilitation therapy in the critically ill (EPICC): a multicentre, parallel-group, randomised controlled trial. Thorax 2018, 73(3), 213-221.
- Pickard RS, Chadwick T, Oluboyede Y, Brennand C, von Willamowitz-Moellendorff A, McClurg D, Wilkinson J, Ternent L, Ainsworth H, Walton K, McColl E, Vale L, Wood R, Abdel-Fattah M, Hilton P, Fader M, Harrison S, Larcombe J, Little P, Timoney A, N'Dow J, Armstrong H, Morris N, Walker K, Thiruchelvam N. Continuous low-dose antibiotic prophylaxis to prevent urinary tract infection in adults who perform clean intermittent self-catheterisation: the AnTIC RCT. Health Technology Assessment 2018, 22(24), i-102.
- Fisher H, Oluboyede Y, Chadwick T, Abdel-Fattah M, Brennand C, Fader M, Harrison S, Hilton P, Larcombe J, Little P, McClurg D, McColl E, Ndow J, Ternent L, Timoney A, Vale L, Thiruchelvam N, von Wilamowitz-Moellendorff A, Wilkinson J, Walton K, Wood R, Pickard RS. Continuous low-dose antibiotic prophylaxis for adults with repeated urinary tract infections (AnTIC): a randomised, open-label trial. The Lancet Infectious Diseases 2018, 18(9), 957-968.
- Brennand C, von Wilamowitz-Moellendorff A, Dunn S, Wilkinson J, Chadwick T, Ternent L, Oluboyede Y, Wood R, Walton K, Fader M, N'Dow J, Abdel-Fattah M, McClurg D, Little P, Hilton P, Timoney A, Morris N, Thiruchelvam N, Lacombe J, Harrison S, Armstrong H, McColl E, Pickard R. Antibiotic treatment for intermittent bladder catheterisation with once daily prophylaxis (the AnTIC study): Study protocol for a randomised controlled trial. Trials 2016, 17, 276.
- Little SA, Leelarathna L, Walkinshaw E, Kai Tan H, Chapple O, Lubina-Solomon A, Chadwick TJ, Barendse S, Stocken DD, Brennand C, Marshall SM, Wood R, Speight J, Kerr D, Flanagan D, Heller SR, Evans ML, Shaw JAM. Recovery of Hypoglycemia Awareness in Long-Standing Type 1 diabetes: A Multicenter 2x2 Factorial Randomized Controlled Trial Comparing Insulin Pump with Multiple Daily Injections and Continuous with Conventional Glucose Self-Monitoring (HypoCOMPaSS). Diabetes Care 2014, 37(8), 2114-2122.
- Price C, Rae V, Duckett J, Wood R, Gray J, McMeekin P, Rodgers H, Portas K, Ford GA. An observational study of patient characteristics associated with the mode of admission to regional acute stroke services. PLoS One 2013, 8, e76997.
- Price C, Rae V, Duckett J, Wood R, Gray J, McMeekin P, Rodgers H, Portas K, Ford GA. An observational study of patient characteristics associated with the mode of admission to acute stroke services in north east England. PLoS ONE 2013, 8(10), e76997.
- Thomson R, Eccles M, Wood R, Chinn DJ. A cautionary note on data sources for evidence-based clinical decisions: Warfarin and stroke prevention. Medical Decision Making 2007, 27(4), 438-447.
- Nath U, Thomson R, Wood R, Ben-Shlomo Y, Lees A, Rooney C, Burn DJ. Population based mortality and quality of death certification in progressive supranuclear palsy (Steele-Richardson-Olszewski syndrome). Journal of Neurology, Neurosurgery and Psychiatry 2005, 76(4), 498-502.
- Pless-Mulloli T, Edwards R, Howel D, Wood R, Paepke O, Herrmann T. Does long term residency near industry have an impact on the body burden of polychlorinated dibenzo-p-dioxins, furans, and polychlorinated biphenyls in older women?. Occupational and Environmental Medicine 2005, 62(12), 895-901.
- Rodgers H, Greenaway J, Davies T, Wood R, Steen N, Thomson R. Risk Factors for First-Ever Stroke in Older People in the North East of England: A Population-Based Study. Stroke 2004, 35(1), 7-11.
- Rodgers H, Oliver SE, Dobson R, Thomson RG. A regional collaborative audit of the practice and outcome of carotid endarterectomy in the United Kingdom. European Journal of Vascular and Endovascular Surgery 2000, 19(4), 362-369.
- O'Mahony PG, Thomson RG, Dobson R, Rodgers H, James OFW. The prevalence of stroke and associated disability. Journal of Public Health Medicine 1999, 21(2), 166-171.
- Rodgers H, Atkinson C, Bond S, Suddes M, Dobson R, Curless R. Randomized controlled trial of a comprehensive stroke education program for patients and caregivers. Stroke 1999, 30(12), 2585-2591.
- O'Mahony PG, Rodgers H, Thomson RG, Dobson R, James OFW. Is the SF-36 suitable for assessing health status of older stroke patients. Age and Ageing 1998, 27(1), 19-22.
- H. Rodgers, J. Soutter, W. Kaiser, P. Pearson, R. Dobson, C. Skilbeck and J. Bond. Early supported hospital discharge following acute stroke: pilot study results. Clinical Rehabilitation 1997, 11, 280-287.
- P.G. O'Mahony,R.G. Thomson,H. Rodgers,R. Dobson,O.F.W. James. Accuracy of the family health services authority register in Newcastle upon Tyne, UK as a sampling frame for population studies. Journal of Epidemiology and Community Health 1997, 51, 206-207.
- P.G. O'Mahony,R. Dobson,R.G. Thomson,H. Rodgers,O.F.W. James. Health status assessment of older stroke patients using the SF-36. Journal of The American Geriatrics Society 1995, 43, 176.
- P.G. O'Mahony,R. Dobson,R.G. Thomson,H. Rodgers. "Have you ever had a stroke? is a sensitive and specific question for assessing stroke prevalence. Age and Ageing 1995.
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Conference Proceedings (inc. Abstract)
- McMeekin P, Gray J, Price C, Rae V, Duckett J, Wood R, Rodgers H, Ford GA. Modeling outcomes following redirection of emergency stroke admissions from ten local stroke units to two neuroscience centres. In: UK Stroke Forum 2012 Conference. 2012, Harrogate, UK: Wiley-Blackwell Publishing Asia.
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Letter
- Little SA, Leelarathna L, Walkinshaw E, Tan HK, Chapple O, Lubina-Solomon A, Chadwick TJ, Barendse S, Stocken DD, Brennand C, Marshall SM, Wood R, Speight J, Kerr D, Flanagan D, Heller SR, Evans ML, Shaw JAM. Response to Comment on Little et al. Recovery of Hypoglycemia Awareness in Long-standing Type 1 Diabetes: A Multicenter 2 x 2 Factorial Randomized Controlled Trial Comparing Insulin Pump With Multiple Daily Injections and Continuous With Conventional Glucose Self-monitoring (HypoCOMPaSS). Diabetes Care 2014;37:2114-2122. Diabetes Care 2014, 37(12), E272-E273.
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Note
- Little SA, Leelarathna L, Walkinshaw E, Tan HK, Chapple O, Lubina-Solomon A, Chadwick TJ, Barendse S, Stocken DD, Brennand C, Marshall SM, Wood R, Speight J, Kerr D, Flanagan D, Heller SR, Evans ML, Shaw JAM. Recovery of hypoglycemia awareness in longstanding type 1 diabetes: A multicenter 2×2 factorial randomized controlled trial comparing insulin pump with multiple daily injections and continuous with conventional glucose selfmonitoring (HypoCOMPaSS). Diabetes Technology and Therapeutics 2016, 18(Suppl. 1), S27-S28.
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Report
- Thomson RG, Rodgers H, Gani A, Dobson R, Herd B, Murphy J. Tees Stroke Register; Summary of final reports to NHS R&D CVD/stroke programme (I: Epidemiology /II: service utilisation). Newcastle Upon Tyne: University of Newcastle, 1999.
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Review
- Thomson R, Greenaway J, Chinn DJ, Wood R, Rodgers H. The impact of implementing national hypertension guidelines on prevalence and workload in primary care: A population-based survey of older people. Journal of Human Hypertension 2005, 19(9), 683-689.