Staff Profile

Roles and Responsibilities

UK's first female Professor of Interventional Cardiology

Honorary Consultant Interventional Cardiologist, Freeman Hospital, Newcastle upon Tyne Hospital NHS Foundation Trust 

National Cardiovascular Specialty Lead, NIHR Research Delivery Network, University of Leeds

Panel member, NIHR Advanced Fellowship Selection Committee

Other Responsibilities: Newcastle University

Academic lead for Cardiology: Department of Health, Modernising Scientific Careers, MSc Cardiac Science Module, Newcastle University (2011-2020)

Academic lead for Cardiology: NIHR Academic Clinical Fellowship, Health Education North East (HENE) (2011-2020)

Academic lead for Cardiology: NIHR Academic Foundation Programme, HENE (2011-2020)

Academic lead for Cardiology: Cardiology Training Programme, HENE (2011-)

Associate Fellow: Graduate School, Newcastle University (2011-)

Lead Supervisor: MBBS Stage 4 SSC in Cardiology and Clinical Cardiology Research, Newcastle University (2011-)

Lead Supervisor: MRes Cardiovascular Science, Newcastle University (2011-)

Other Responsibilities: National and International

Faculty Member BAIM Institute for Clinical Research, Boston, MA, USA

British Cardiovascular Intervention Society (BCIS): Research and Development Working Group Lead 2022 (2023-2026)

European Association of Percutaneous Cardiovascular Interventions EAPCI: Executive Committee Board Member 2022-2024

European Society of Cardiology: Invited Member Education Committee (2022 to 2024): Task Force Lead/Co-ordinator E-learning ESC Education Committee

British Cardiovascular Intervention Society (BCIS): Steering Committee Member, Research and Development Group (2015 to Date). National Theme Lead Acute Myocardial Infarction BCIS/BHF Clinical Research Collaborative

European Society of Cardiology: Invited Member, Communications Committee (2024-2026)

Invited Member Education Committee (2018 to 2024): Task Force Lead/Director ESC Guidelines Webinar Series; Task Force Lead ESC Endorsement Policy

European Society of Cardiology: Invited Member European Regulatory Affairs Committee (2018 to date)

European Society of Cardiology: Country Ambassador Patient Forum (2018-2020)

European Association of Percutaneous Cardiovascular Interventions EAPCI Database Registries Committee EAPCI Board 2020-2022

Co-Chair, European Society of Cardiology ESC/European Association of Percutaneous Cardiovascular Interventions EAPCI Scientific Documents and Initiatives Committee ESC/EAPCI Board 2018-2020

European Society of Cardiology/European Association of Percutaneous Cardiovascular Interventions (EAPCI): Steering Committee Member, Women's Committee, International Collaborations Lead (2013-current)

European Society of Cardiology/European Association of Percutaneous Cardiovascular Interventions (EAPCI): Steering Committee Member, Young Interventionalist Committee, Research Lead, Curriculum/Exam Development Committee, Representation in ESC Cardiologists of Tomorrow Committee on behalf of EAPCI Young (2013-2018)   

European Society of Cardiology/European Association of Percutaneous Cardiovascular Interventions (EAPCI): EUROPCR Programme Committee (2017, 2018, 2019)

European Society of Cardiology: Nucleus member, Working Group on Thrombosis

American College of Cardiology: Fellow, Abstract Reviewer, Scientific Sessions, USA

European Society of Cardiology: Fellow, Abstract Reviewer, Faculty member, Scientific Sessions, Europe

Transcatheter Cardiovascular Therapeutics: Abstract Reviewer, Faculty member, Scientific Sessions USA

Editorial Responsibilities:

AsiaIntervention Senior Editorial Consultant

European Heart Journal Digital Health- Associate Editor

Heart- Associate Editor, Education in Heart

Circulation Cardiovascular Interventions-Editorial Board

European Heart Journal- Case Reports- Associate Editor (Completed)

Advances in Interventional Cardiology- Associate Editor

Eurointervention Journal- Associate Editor (Completed)

Eurointervention Journal (Section Editorial Consultant)

PCROnline Journal Club- Editorial Team Member

Eurointervention Journal- Social Media Editorial Team Member (Completed)

Qualifications

Leadership for the future of work, Newcastle University 2022

Inclusive Futures Leadership Programme, Newcastle University 2021

Women Transforming Leadership Programme, Said Business School, University of Oxford

Postgraduate Diploma in Clinical Trials, University of London (London School of Hygiene and Tropical Medicine), UK

FESC Fellow of the European Society of Cardiology, Europe

FACC Fellow of the American College of Cardiology, USA

FRCP Fellow of Royal College of Physicians Edinburgh, UK

MD Newcastle University, UK

MRCP Royal College of Physicians Edinburgh, UK

MBBS 

Postgraduate and Academic Training

General and Internal Medicine, Northern Deanery, UK

General and Interventional Cardiology, Northern Deanery, UK

Research Scholar: TIMI/PERFUSE Angiographic Core Lab, Brigham and Women's Hospital, Harvard Medical School, Boston MA, USA

Research Registrar: The James Cook University Hospital, Middlesbrough, UK 

Invited Peer Reviewer for journals and funding bodies

The American Journal of Cardiology, Heart, Herz, Catheterization and Cardiovascular Intervention, Journal of Interventional Cardiology, The Lancet, American Heart Journal, Open Heart, Circulation and many others

Expert grant reviewer: Medical Research Council (MRC), NIHR, BHF, European Commission, Heart Research UK

Expert technology appraiser: NICE

External Examiner

2024 Doctor of Philosophy, UMC Amsterdam (Dr. Feenstra)

2024 Doctor of Philosophy, Karolinska University, Stockholm, Sweden (Dr. Irene Santos)

2018 Doctor of Philosophy, Kings College London (Dr. Natalia Briceno)

2017 Doctor of Philosophy Marie Curie University, Paris (Dr. Nicole Karam)

2016 Doctor of Philosophy University of Glasgow (Dr. Jamie Layland)

Membership of Professional Societies (Current):

General Medical Council (Full)

British Medical Association

Royal College of Physicians, Edinburgh

British Cardiovascular Interventional Society

European Association of Percutaneous Cardiovascular Intervention

ESC Working Group on Thrombosis- member

ESC Acute Cardiovascular Care - member

European Society of Cardiology

British Cardiovascular Society

Invited Faculty/Speaker National and International Cardiology Societies

Chair: Royal College of Physicians Edinburgh Cardiology Symposium 2016 Organising Committee

European Society of Cardiology Congress 2015 to date

EUROPCR 2016 to date

Transcatheter Cardiovascular Therapeutics, USA 2010 to date 

British Cardiovascular Intervention Society, London, UK 2011 to date

British Cardiovascular Society

American College of Cardiology

World Heart Federation 

Portuguese Cardiac Society

Portuguese Intervention Society

Belgrade-Serbian Intervention Cardiac Society

Royal College of Surgeons and Physicians Glasgow

European Bifurcation Club

Latin American Society of Cardiology

American Heart Association

Global Cardiovascular Trialists Forum

Grand rounds speaker Sydney Australia

German Cardiac Society 2023

European Society of Clinical Investigation 2023

Awards, Honours, Media Fellowships ICON Study Group

Late breaking presentation, ESC Congress SENIOR RITA trial, 2024

Indonesian Cardiac Society, Plenary speaker on behalf of European Society of Cardiology, 2024

Plenary Lecture, Malaysian Cardiac Society, on behalf of European Society of Cardiology, 2024

Newcastle University EDI Committee, International women’s day invited keynote: Breaking the glass ceiling in cardiology, 2024

Love and cardiovascular health, BBC News and BBC Look North, 2024

British Cardiovascular Society- Women in Cardiology, invited keynote: Is academic cardiology future bright? 2024

Newcastle University Cardio Society, invited keynote: Is academic cardiology future bright? 2024

Newcastle University EDI Committee, International women’s day invited keynote: Breaking the glass ceiling in cardiology, 2024

Cardiovascular Grand Rounds, Hamburg, Germany, 2024

Mail on Sunday Women and Cardiovascular Disease 2023

Inspirational Woman Newcastle University 2023

Newcastle University Insights Public Lecture 2023

Heart BMJ Podcast, Women and Cardiovascular Disease 2023

BBC Radio 4 Interview Women and Cardiovascular Disease 2023

Disruptor for Good, Northern Power Women Award Shortlist 2023

Inspirational Lecture, Newcastle University MSc Clinical Scientist Programme, 2022

Disruptor for Good, Northern Power Women Award Nomination 2022

British Heart Foundation Research Engagement Heart Hero Award Shortlist 2022

Royal College of Physicians and Surgeons of Glasgow, Presidential commendation for first female Professor of Interventional Cardiology, March 2022

UK Department of Health National Clinical Excellence Award 2022

Invited Speaker, Gender Equality and Equity in Healthcare, United Nations Commission on the Status of Women March 2021

Eurointervention award for INOCA Consensus document, Top Almetrics 2021

Channel 4 Documentary: Women and Heart Disease, 2021

EAPCI INOCA Consensus Top Almetrics, Top downloaded Eurointervention, 2020

Wolfson Foundation Intercalated Award, MRes Mr. Greg Mills (VK Lead Supervisor), 2020

British Heart Foundation Alumni event Edinburgh 2019: Guest Speaker Bias and Biology, 2019

British Heart Foundation Guest Speaker Bias and Biology Campaign Leeds, 2019

NICOR- "Better than expected survival 30 days post PCI" 2019

UK Commissioner, The Lancet Commission- Cardiovascular Disease in Women, 2019

BBC News Campaign, The British Heart Foundation Bias and Biology, London 2019 

Panel Member, The British Heart Foundation Bias and Biology, London 2019

WINNER The Times, The Sunday Times We Are The City Healthcare RISING STAR Award 2018

Finalist We Are The City Healthcare RISING STAR Award 2018 Powered by The Times, The Sunday Times #watctop100

ITV Tyne Tees News, Public Health England Heart Age Campaign 2019 

European Society of Cardiology Educational Grant Award 2018 to Dr. Sophie Gu (VK Lead Supervisor)

British Cardiovascular Society Annual Conference Award 2018 to Dr. Sophie Gu (VK Lead Supervisor)

Newcastle Cardiovascular Research Centre Best Oral Abstract Award 2018 to Lucy Lawson (VK Lead Supervisor) 

The Frank Knox Memorial Harvard Fellowship 2016-2017 Award to Dr. Jonathan Batty (VK Lead Supervisor)

The Barbour Foundation Scholarship Award 2015-2016 to Mr. Benjamin Beska (VK Lead Supervisor) 

Best abstract award ICON1 study, American College of Cardiology Scientific Sessions- Geriatric Cardiology Group 2015, San Diego 

Winning Moderated Poster Award, European Society of Cardiology Congress 2014, Barcelona

American Heart Association International Mentorship Award 2014 to Dr Denton (VK Lead Supervisor)

Finalist, TCT 2010, Thomas J Linnemeier Young Investigator Award- Washington DC.

Google Scholar: Click here.

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Group Name: ICON Study Group

Despite significant developments in pharmacotherapy and interventional strategies, cardiovascular disease (CVD) is the leading cause of mortality in the UK and worldwide. I am committed and passionate about improving outcomes for neglected patient groups such as older adults and women with CVD. My group’s research interests thus far primarily focussed on addressing the unmet needs of improving cardiovascular outcomes under the acronym ICON (Improve Cardiovascular Outcomes in High Risk PatieNts) in this neglected cohort of patients. My commitment, dedication, perseverance and hard work have enabled me to be successful with several prestigious external grants and gain national/international standing in cardiovascular medicine. Women are underrepresented in my specialty. I champion diversity as a role model (5% of interventional cardiologists are female in the UK, <1% are clinical academics). In 2022, I became the first female interventional cardiologist in the UK to be promoted to a University Personal Chair. I have published >235 publications (H index 58-Google Scholar) in major journals including the New England Journal of Medicine and the Lancet. 

Chief Investigator: ICON 1 Study (Completed) Funder: Newcastle NIHR BRC (3 Years)

A Study to Improve Cardiovascular Outcomes in High Risk PatieNts with Acute Coronary Syndrome : UKCRN ID 12742.

Ischaemic heart disease (IHD) is the leading cause of death worldwide. There has been rapid progress in the management of acute coronary syndromes over the last decade with the use of adjunctive pharmacotherapy, specifically novel antiplatelets and anticoagulants, and advanced percutaneous coronary intervention (PCI) techniques. These medical and technical advancements have led to improved survival and gains in life expectancy, especially in younger individuals (<65 years of age) and in men. There is a steep increase in mortality due to ischaemic heart disease among those aged >70 years of age. Despite the increasing burden of ischemic heart disease among the ageing population, there are few studies evaluating novel therapies and interventions among older patients to improve their cardiovascular outcomes in this growing ageing population. My current research focuses to determine the predictors of poor quality of life and adverse outcomes following PCI for acute coronary syndrome in older patients by evaluating frailty scores, biomarker profile, non-invasive cardiovascular parameters (CIMT, vascular stiffness, endothelial function, diastolic function) and invasive imaging (coronary angiography, virtual histology intravascular ultrasound, optical coherence tomography) to develop an integrated risk score to predict outcomes and inform clinical decision making.

Chief Investigator: APPLE-COPD: ICON 2 Study (Completed) Funder: Astra Zeneca (2 Years) 

Antiplatelet therapy in the primary prevention of cardiovascular disease in patients with COPD.

Patients with COPD (chronic bronchitis and/or emphysema) are known to be at an increased risk of heart disease and death due to heart attacks. There are several possible reasons for this, one of which is an increased tendency of the blood to clot, that can give rise to blood clot formation in the coronary arteries, and lead to heart attack. Medications such as Aspirin and another new blood thinning tablet called Ticagrelor are already used for patients with heart attacks. Given that patients with COPD are at higher risk of heart attack, we wish to see if these tablets that can prevent blood clot formation in heart arteries might also prevent heart attacks happening in COPD patients. We hope to understand the effects by measuring clotting and inflammation in the blood. All patients will be followed up for 6-months. We also wish to study COPD patients who do not have high risk of developing future heart problems using the QRISK score to study their well being over a 1 year period to see if these patients might also benefit from blood thinning medications.

UK Chief Investigator: The British Heart Foundation SENIOR-RITA Trial (Ongoing) Funder: The British Heart Foundation Clinical Study Grant CS/15/7/31679 (7 Years)

The British Heart Foundation older patients with non-ST SEgmeNt elevatIOn myocaRdial infarction Randomized Interventional TreAtment Trial 

Our population is ageing. Age is a powerful predictor of adverse events following acute myocardial infarction and percutaneous coronary intervention (PCI): adjusted odds for in-hospital death increase by 70% for each 10-year increase in age. Older patients are often frail with up to a half of older patients (≥75 years) admitted with non-ST elevation myocardial infarction (NSTEMI) being severely frail. These frail older patients have a 4-fold increased risk of death at 1-year and yet are often denied coronary revascularisation because of fear of complications and causing harm. The goals of this study are to determine the benefit and risk of coronary revascularisation versus conservative management in high-risk older patients presenting with non-ST elevation myocardial infarction (NSTEMI) and receiving optimal medical therapy. We will explore the predictors and mechanisms of benefit and risk in relation to clinical outcomes, quality of life, and frailty scores.

Invasive Treatment Strategy for Older Patients with Myocardial Infarction | New England Journal of Medicine

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Recruitment strategies for the BHF SENIOR RITA trial

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Chief Investigator: ASPIRE Study (Completed) Funder: Research Capability Fund (2 Years)

Aspirin Resistance Among Pregnant Women at Risk of Preeclampsia: UKCRN ID 14468. 

Cardiovascular diseases (CVD) remain the leading cause of death particularly among younger women. Diseases such as preeclampsia and gestational diabetes are unique among women that lead to poor outcomes including the occurrence of myocardial infarction and death in the future. Strategies to prevent such pregnancy related diseases are required to improve clinical outcomes among women. The current study is designed to determine the benefit of the use of low dose aspirin (ASA) among women at risk of preeclampsia. Given not all patients respond to aspirin therapy adequately in terms of platelet inhibition, the present study will determine response to aspirin therapy among pregnant women at risk of preeclampsia using specialised platelet function assays (Verify Now, Multiplate, serum thromboxane B₂ and urine 11-Dehydrothromboxane B2). Data collected in this pilot study will be used to develop a proposal for a randomised controlled study of the effectiveness of aspirin dosage adjustment according to bedside platelet function testing for the prevention of preeclampsia.

UK National Coordinating Investigator: TWILIGHT Study (Completed)

Sponsor: Mount Sinai School of Medicine New York, USA Funder: Astra Zeneca

The purpose of this study is to compare the use of ticagrelor alone versus ticagrelor and aspirin together. Both ticagrelor and aspirin stop platelets from sticking together and forming a blood clot that could block blood flow to the heart. This study will look to determine the effectiveness and safety of ticagrelor alone, compared to ticagrelor plus aspirin in reducing clinically relevant bleeding and in reducing ischemic adverse events among high-risk patients who have had a percutaneous intervention with at least one drug-eluting stent. A patient is considered high-risk if they meet certain clinical and/or anatomic criteria. Up to 9000 subjects will be enrolled at the time of their index PCI. Subjects meeting randomization eligibility criteria at 3 months post enrolment will be randomized to either ticagrelor plus aspirin or ticagrelor plus placebo for an additional 12 months. Follow-up clinic visits will be performed at 3 months, 9 months and 15 months post enrolment.

UK National Coordinating Investigator: XIENCE SHORT DAPT Trial (Completed)

Sponsor: Abbott Vascular Santa Clara, CA, USA Funder: Abbott Vascular

This is a prospective, single arm, multi-centre, open label trial to evaluate the safety of 3-month DAPT in subjects at high bleeding risk (HBR) undergoing percutaneous coronary intervention (PCI) with the approved XIENCE family (The XIENCE family stent systems include commercially approved XIENCE drug-eluting stents. Eligibility of P2Y12 receptor inhibitor discontinuation will be assessed at 3-month follow-up. Subjects who are free from myocardial infarction (MI), repeat coronary revascularization, stroke, or stent thrombosis (ARC definite/probable) within 3 months after stenting and have been compliant with 3-month DAPT without interruption of either aspirin and/or P2Y12 receptor inhibitor for > 7 consecutive days are considered as "3-month clear", and will discontinue P2Y12 receptor inhibitor and continued with aspirin monotherapy after 3-month follow-up. All registered subjects will be followed at 3, 6 and 12 months post index procedure. The data collected from this study will be compared with the historical control of HBR subjects.

UK National Coordinating Investigator: PACIFIC AMI Trial (Completed)

Sponsor: Bayer, Berlin, Germany Funder: Bayer, Berlin, Germany

This trial evaluates whether the oral FXIa inhibitor BAY 2433334 compared to placebo leads to a lower incidence of cardiovascular (CV) death, MI, stroke and stent thrombosis in participants with an acute myocardial infarction and who are treated with dual antiplatelet therapy.

UK National Coordinating Investigator: AEGIS 2 Trial (Completed)

Sponsor: CSL Behring, Beth Israel Deaconess Medical Centre Boston MA

This is a phase 3, multicenter, double-blind, randomized, placebo-controlled, parallel-group study to evaluate the efficacy and safety of CSL112 on reducing the risk of major adverse CV events (MACE) in subjects with ACS (diagnosed with STEMI or NSTEMI), who are receiving evidence-based medical therapy.

UK National Coordinating Investigator and Steering Committee Member: COMPLETE 2 Trial

Sponsor: Population Health Research Institute Canada

A randomized trial of physiology-guided versus angiography-guided non-culprit lesion (NCL) complete revascularization strategies in patients with acute myocardial infarction and multivessel coronary artery disease. In patients with acute ST-segment elevation myocardial infarction (STEMI) or non-ST-segment elevation myocardial infarction (NSTEMI) and multivessel coronary artery disease (CAD) who have undergone successful culprit lesion Percutaneous Coronary Intervention (PCI):

1. To determine whether a strategy of physiology-guided complete revascularization (using fractional-flow reserve [FFR] or resting full cycle ratio [RFR]) is non‐inferior to a strategy of angiography‐guided complete revascularization on the efficacy composite outcome of cardiovascular (CV) death, new myocardial infarction (MI) or ischemia‐driven revascularization (IDR).

2. To determine whether a physiology-guided complete revascularization strategy is superior to an angiography-guided complete revascularization strategy in reducing the safety composite outcome of clinically significant bleeding, stroke, stent thrombosis or contrast-associated acute kidney injury.

Trial Executive Committee Member: ARTEMIS AMI Trial

Sponsor: Novo Nordisk

The research study is being done to see if ziltivekimab can be used to treat people who were admitted to hospital because of a heart attack. Ziltivekimab might reduce development of heart disease, thereby preventing new heart attacks or strokes. Participants will either get ziltivekimab (active medicine) or placebo (a dummy medicine which has no effect on the body). Which treatment participants get is decided by chance. The chance of getting ziltivekimab or placebo is the same. Ziltivekimab is not yet approved in any country or region in the world. It is a new medicine that doctors cannot prescribe. The study will last for about 2 years.

Local Principal Investigator: 

MVO/REFLOW MI Trial (Completed): Randomized Controlled Trial Comparing Intracoronary Administration of Adenosine or Sodium Nitroprusside to Control for Attenuation of Microvascular Obstruction During Primary Percutaneous Coronary Intervention - UKCRN ID 12168

Strategies to attenuate micro-vascular obstruction during P-PCI: the randomized reperfusion facilitated by local adjunctive therapy in ST-elevation myocardial infarction trial | European Heart Journal | Oxford Academic

EVOLVED Trial (Completed): Early valve replacement guided by biomarkers of left ventricular decompensation in asymptomatic patients with severe aortic stenosis NCT03094143

Early Intervention in Patients With Asymptomatic Severe Aortic Stenosis and Myocardial Fibrosis: The EVOLVED Randomized Clinical Trial | Valvular Heart Disease | JAMA | JAMA Network

COMPLETE Trial (Completed): A randomised, comparative effectiveness study of complete versus culprit-only revascularization strategies to treat multi-vessel disease after primary percutaneous coronary interventions for ST-segment elevation myocardial infarction - UKCRN ID 15425

Complete Revascularization with Multivessel PCI for Myocardial Infarction | New England Journal of Medicine

IDORSIA Trial (Completed): A multi-center, double-blind, randomized, placebo-controlled study to assess the pharmacodynamics, pharmacokinetics, tolerability, and safety of a single subcutaneous injection of ACT-246475 in adults with stable coronary artery disease

ESC EORP Registry (Completed): Registry of management of NSTEMI patients.

Pharmacodynamics, pharmacokinetics, and safety of single-dose subcutaneous administration of selatogrel, a novel P2Y12 receptor antagonist, in patients with chronic coronary syndromes | European Heart Journal | Oxford Academic

iModern Trial: In patients with acute ST-elevation myocardial infarction (STEMI), 40-60% have multi-vessel disease with an increased cardiovascular morbidity and mortality. Although it is not recommended to revascularize noninfarct lesions during the acute intervention, recent investigations suggest the opposite and show improved outcome after direct revascularization of all noninfarct lesions. It is undesirable to risk procedure-related complications by treating noninfarct lesions without impaired flow. It is currently unknown whether pressure guided revascularization of noninfarct lesions in the acute phase improves outcome compared to the current guidelines. The iMODERN trial will compare an iFR-guided intervention of noninfarct lesions during the acute intervention with a deferred stress perfusion CMR-guided strategy during the outpatient follow-up, to determine the optimal therapeutic approach for STEMI patients with multivessel lesions. The study is a prospective, randomized controlled, multicentre study. Status: Completed

ESC EORP NSTEMI Registry: The aim of the ‘EURObservational Research Programme (EORP) NSTEMI registry’ is to improve the clinical outcomes of patients hospitalised with NSTEMI, through the identification and reporting of sub-optimal delivery of guidelineindicated care. Primary Objective 1: To quantify the gaps in the management of acute coronary syndromes in patients presenting without persistent ST segment elevation versus the current guidelines and describe the inter countries differences. Primary Objective 2: To analyse and report these data as research publications and health reports to the wider ESC community. Status: Completed

Presentation, care, coronary intervention and outcomes of patients with NSTEMI according to age: insights from the international prospective ACVC-EAPCI EORP NSTEMI registry | Age and Ageing | Oxford Academic

Cohort profile: the ESC EURObservational Research Programme Non-ST-segment elevation myocardial infraction (NSTEMI) Registry - PubMed

Presentation, care, and outcomes of patients with NSTEMI according to World Bank country income classification: the ACVC-EAPCI EORP NSTEMI Registry of the European Society of Cardiology | European Heart Journal - Quality of Care and Clinical Outcomes | Oxford Academic

Sex-specific presentation, care, and clinical events in individuals admitted with NSTEMI: the ACVC-EAPCI EORP NSTEMI registry of the European Society of Cardiology | European Heart Journal. Acute Cardiovascular Care | Oxford Academic

Diabetes mellitus and presentation, care and outcomes of patients with NSTEMI: the Association for Acute Cardiovascular Care-European Association of Percutaneous Cardiovascular Interventions EURObservational Research Programme NSTEMI Registry of the European Society of Cardiology - PubMed

SOS AMI Trial: Multi-center, double-blind, randomized, placebo-controlled, parallel-group study to evaluate the efficacy and safety of self-administered subcutaneous selatogrel for prevention of all-cause death and treatment of acute myocardial infarction in subjects with a recent history of acute myocardial infarction. The primary objective of the study is to assess the clinical efficacy of selatogrel when self-administered upon occurrence of symptoms suggestive of an acute myocardial infarction (AMI) in subjects at risk of having a recurrent AMI. The secondary objective is to assess the safety of self-administration of selatogrel.

OCEANIC AF Trial: Sponsor Bayer Completed. Multicentre, randomized, active comparator-controlled, double-blind, double-dummy, parallel group phase III study of the oral FXIa inhibitor BAY 2433334 for the prevention of stroke or systemic embolism in patients with atrial fibrillation. The primary efficacy objective is to demonstrate the effect on prevention of stroke and systemic embolism of BAY 2433334 when compared to apixaban in patients with atrial fibrillation. The primary safety objective is to demonstrate that the oral FXIa inhibitor BAY2433334 is superior to apixaban as assessed by ISTH major bleeding in patients with atrial fibrillation.

Asundexian versus Apixaban in Patients with Atrial Fibrillation | New England Journal of Medicine

EASY –AS Trial: Sponsor Leicester University In recruitment phase. Aortic Stenosis (AS) is the commonest valve disease requiring surgery but the risks and benefits of a strategy of early AVR versus expectant management in asymptomatic patients are unclear. The Early valve replacement in severe ASYmptomatic AS (EASY-AS) study will test the hypothesis that early AVR results in reduced incidence of the primary outcome, a composite of cardiovascular death and heart failure hospitalisation when compared to a guideline recommended strategy of expectant management. Using a pragmatic multicentre prospective parallel group RCT design, the study will randomise up to 2844 patients with severe asymptomatic AS. 

ORFAN Study: The Oxford Risk Factors And Non-invasive imaging (ORFAN) study is the world’s largest clinical cohort of consecutive individuals undergoing clinically indicated coronary computed tomography angiography (CCTA). From Newcastle I will be providing CCTA of >13,000 patients to the ORFAN study. Specifically, I will evaluate female patients with non-obstructive coronary arteries using CCTA which again will strengthen my portfolio of work advancing the care of women with CVD.

Inflammatory risk and cardiovascular events in patients without obstructive coronary artery disease: the ORFAN multicentre, longitudinal cohort study - The Lancet

Clinical trial leadership:

National theme Lead Acute Coronary Syndrome, BCIS/BHF Clinical Research Collaborative

Country lead, Member Executive Steering Committee: TWILIGHT trial

Country lead, Member Trial Steering Committee: XIENCE SHORT DAPT Trial

Country lead: PACIFIC AMI trial

Chair Trial Steering Committee: ICORMICA trial

Country lead, Member Trial Steering Committee: AEGIS 2 Trial

Member, Data Monitoring Committee: The BHF DUAL ACS2 Trial

Member, Executive Steering Committee: ESC EORP NSTEMI registry

Member, Steering Committee ESC EUROHEART Cardiovascular Outcomes Registry

Executive Committee: ARTEMIS Trial

Steering Committee/Country Lead: COMPLETE 2 Trial

Chair Trial Steering Committee: SOPHIST Trial

International Clinical Practice Guidelines Task Force:

European Society of Cardiology 2024 Clinical Practice Guidelines on Chronic Coronary Syndrome. Chapter Leader: INOCA and special population

2024 ESC Guidelines for the management of chronic coronary syndromes | European Heart Journal | Oxford Academic

European Society of Cardiology 2023 Clinical Practice Guidelines on Acute Coronary Syndrome. Chapter Leader: MINOCA/INOCA; Section contributor: Special populations-Older adults with frailty and multi-morbidity; Pregnancy.

2023 ESC Guidelines for the management of acute coronary syndromes | European Heart Journal | Oxford Academic

Undergraduate Teaching and Supervision

Supervisor: Student Selected Components (SSC) Stage 4 MBBS Students- Newcastle University

Personal Tutor: Stage 1 and Stage 3 Medical Students- Newcastle University

Postgraduate Teaching

Academic Lead Cardiology/Instructor: Department of Health Modernising Scientific Careers MSc in Cardiovascular Science, Newcastle University Modules CVR 8001, CVR 8004, CVR 8007 (Completed)

Lead Supervisor: Masters by Research (MRes), Newcastle University 

Lead Supervisor-Postgraduates, Newcastle University:

Doctor of Philosophy (PhD)

Dr. Hannah Sinclair MB ChB MRCP (Completed 2019)

Dr. Hanna Ratcovich (PhD-Copenhagen University/Newcastle University)

Dr. Graziella Pompei (University of Ferara/Newcastle University, 2023-2026)

Dr. Wanqi Wang MBBS (PhD 2025-2028)

Doctor of Medicine (MD Research)

Dr. Murugapthy Veerasamy MBBS MRCP (Completed 2019)

Dr. Hani Ali MBBS MRCP (Completed 2021)

International visiting researchers

Dr. Hanna Ratcovich (Copenhagen University, 2022)

Dr. Francesca Rubino, University of Verona, Italy, 2023

Dr. Graziella Pompei, University of Ferrara, Italy, 2023-2024

NIHR Academic Foundation Programme in Cardiology

Dr. Jonathan Batty BSc MB ChB (2014-2016), Winner Harvard Frank Knox Fellowship

Dr. Benjamin Beska MBBS MRes (2017-2019)

NIHR Academic Clinical Fellowship in Cardiology

Dr. Bilal Bawamia MBBS MRCP (2012-2013)

Dr. Sophie Gu MBBS MRCP (2016-2019)

Dr. Danny Chan MBBS PhD (2017-2020)

Dr. Benjamin Beska MBBS MRes (2019-2022)

Dr. Mike Lawless MBBS PhD (2020-2023)

Dr. Christos Kotanidis MBBS PhD (2022-24)

NIHR Academic Clinical Lecturer in Cardiology

Dr. Chris Wilkinson MBBS MD (2019-2022)

Lead Research Supervisor-Newcastle University BSc/MRes/MSc Students (2014 to date):

Mr. Alkanz Firdaus MRes (Newcastle University), 2024

Dr. Wanqi Wang MBBS/MRes (Newcastle University), 2024

Ms. Valerie Dirjayanto MBBS/MRes (Newcastle University-Indonesia Medical School), 2023

Mr. Dennis Sukadana MBBS/MRes (Newcastle University-Indonesia Medical School), 2022

Mr. Greg Mills MBBS/MRes (Newcastle University), 2021 Distinction

Mr. Daniell Edward MBBS MRes (Newcastle University-Indonesia Medical School), 2021 Distinction

Ms Emma Morrison MBBS/MRes (Newcastle University), 2020 Distinction- Angiographic outcomes in ICON1 study

Ms. Evita Stephanie MBBS/MRes (Newcastle University), 2020 Distinction- Biomarker analysis in ICON1 study

Mr. Daniel Coakley MBBS/MRes (Newcastle University), 2019 Pass with Merit-Thesis Title: Quality of Life Outcomes in older Patients with NSTEACS in ICON1

Mr. Fateh Singh MBBS/MRes (Newcastle University), 2019 Pass-Thesis Title: An analysis of angiographic parameters as predictors of frailty in the ICON1 study 

Ms. Charlotte Lewis BSc (Newcastle University), 2019 Pass with Distinction- Thesis Title: Challenges in recruiting high-risk, elderly patients to cardiovascular clinical trials: A comparison of the BHF SENIOR RITA Trial with previous trials

Ms. Taghreed Jamal BSc (Newcastle University), 2019 Pass with Distinction- Thesis Title: Differences in change across domains of cognition following invasive management of NSTEACS in older adults: Findings from ICON1

Ms. Lucy Lawson MBBS/MRes (Newcastle University), 2018 Pass with Distinction (Winner best abstract award)- Thesis Title: Assessing the promoters and barriers to the recruitment of older patients into CV clinical trials: A mixed methods study based on the BHF SENIOR-RITA Trial

Ms. Amina Khan MBBS/MRes (Newcastle University), 2018 Pass with Distinction-Thesis Title: The association of angiographic parameters with cognition and frailty in older patients with NSTEACS in ICON1

Ms. Shobana Anpalakhan MBBS/MRes (Newcastle University) 2017, Pass with Merit- Thesis Title: NSTEMIs in the elderly: Factors influencing trial recruitment and management as observed from the BHS SENIOR RITA Trial screening

Mr. Adam Miller MBBS/MRes (Newcastle University) 2017, Pass with Merit- Thesis Title: The effect of platelet reactivity on arterial stiffness and lung function in COPD

Ms. Amy Burrell BSc (Newcastle University) 2017, Pass with Distinction- Thesis Title: Angiographic analysis of high risk older patients undergoing coronary angiography ICON1

Mr. Benjamin Beska MBBS (Newcastle University) 2016 (MRes Pass with Distinction)- Thesis Title: The Role of Vitamin D and Parathyroid Hormone as Biomarkers in Older Patients with Non-ST Elevation Acute Coronary Syndrome: The ICON1 Biomarker Sub-study

Ms. Rebecca Jordan MSc (Newcastle University) 2016 (MSc Pass with Distinction)- Thesis Title: Evaluation of pattern of coronary artery disease in older patients with non ST elevation acute coronary syndrome

Ms. Shristy Subba BSc MRes Cardiovascular Science, Newcastle University-2015 (Pass)- Thesis Title: Characterisation of coronary artery plaque composition using virtual histology intravascular ultrasound imaging in older patients with non-ST elevation myocardial infarction

Dr. Meedya Sharifpour MBBS MRes (Keele University)- 2014 (Merit)- Thesis Title: Association of Circulating Inflammatory Biomarkers, Cardiovascular Function and Frailty Among Older Patients with Acute Coronary Syndrome

Dr. Kimberly Batanghari MBBS MRes (Indonesia)- 2014 (Merit)- Thesis Title: ICON1: Association Between Ageing and The Pattern of Coronary Artery Disease in Older Patients With Acute Coronary Syndrome

Ms. Stephanie Paleri BSc (Newcastle University), 2020, Challenges in recruitment of older patients in research

Mr. Regan Cooper BSc (Newcastle University), 2020 Merit-Biomarker analysis in ICON1 study

Ms. Charlotte Pearson BSc (Newcastle University), 2018 Pass with Distinction

Ms. Nasreen Khathun BSc (Newcastle University), 2018 Pass with Merit

Ms. Dhiluni Kandage BSc (Newcastle University) 2014 (Completed with Distinction)- Thesis Title: A comparison of coronary angiographic variables among frail versus non-frail older patients undergoing percutaneous coronary intervention 

Ms. Jennie Parker BSc (Newcastle University) 2014 (Completed with Distinction)- Thesis Title: The association between carotid intima-media thickness and angiographic SYNTAX score 

MBBS, Newcastle University:

2024: Kieran Gill; 2023: Nandine Ganzorig, Academy of Medical Sciences Inspire Programme; 2021: James Jackson, Navin Balasubramanian 2020: Greg Mills, Ben Rowland, Jordan Ng, Jeremy Naylor Wardle. 

Manuscripts Published by Stage 4 MBBS SSC (past):

1. Kuldeepa Ghoorah, Peter Campbell, Alexandra Kent, Annette Maznyczka, Vijay Kunadian. Obesity and cardiovascular outcomes: a review. European Heart Journal: Acute Cardiovascular Care 2016 Feb;5(1):77-85
2. Raheel Ahmed, Joseph Dunford, Roxana Mehran, Stephen Robson, Vijay Kunadian. Preeclampsia and Future Cardiovascular Risk among Women: A Review. Journal of the American College of Cardiology 2014;63(18):1815-22.
3. Vijay Kunadian, Hannah Sinclair, Aaron Sutton, George Dangas. Aspirin, Platelet P2Y12 Receptor Inhibitors and other Oral Antiplatelets: Comparative Pharmacology and Role in Elective PCI. Interventional Cardiology Clinics 2013; Vol. 2, Issue 4, Pages 527-535.
4.  Vijay Kunadian, Joseph Dunford, Daniel Swarbrick, C Michael Gibson. Triple antiplatelet therapy and combinations with oral anticoagulants after stent implantation. Interventional Cardiology Clinics 2013; Vol. 2, Issue 4, Pages 595-606.
5.  Vijay Kunadian, Andrew Harper, Bilal Bawamia, Azfar Zaman. Drug eluting stents versus bare metal stents in primary PCI. Future Medicine Dec 2012; Vol. 4, No. 6, Pages 689-700.
6. Kuldeepa Ghoorah, Anthony De Soyza, Vijay Kunadian. Increased Cardiovascular Risk in Patients with Chronic Obstructive Pulmonary Disease and the Potential Mechanisms Linking the Two Conditions: A Review. Cardiology in Review. 2013 Jul-Aug;21(4):196-202.
7. Andrew Pugh, John Bourke, Vijay Kunadian. Sudden Cardiac Death in Athletes and the Potential Role of Screening in its Prevention. Post Graduate Medical Journal. 2012; Jul;88(1041):382-90
8. Vijay Kunadian, Andrew Pugh, Azfar Zaman, Weiliang Qiu. Percutaneous Coronary Intervention among Patients with Severe Left Ventricular Dysfunction: A Review and Meta-analysis of 19 Clinical Studies. Coronary Artery Disease 2012; 23(7):469-79.
9. Backshall J, Ford GA, Bawamia B, Quinn L, Trenell M, Kunadian V. Physical Activity in the Management of Patients with Coronary Artery Disease: A Review. Cardiology in Review. 2014
10. Raheel Ahmed, Kuldeepa Ghoorah, Vijay Kunadian. Abdominal Aortic Aneurysms and Risk Factors for Adverse Events: A Review. Cardiology in Review.2016 Mar-Apr;24(2):88-93
11. Carpenter M, Sinclair H, Kunadian V. Carotid Intima Media Thickness and Its Utility as a Predictor of Cardiovascular Disease. A Review of Evidence. Cardio Rev. 2016; 24(2):70-5
12. Tan YC, Sinclair H, Ghoorah K, Teoh X, Mehran R, Kunadian V. Gender differences in outcomes in patients with acute coronary syndrome in the currentera: A review. Eur Heart J Acute Cardiovasc Care 2015 

• Articles

  • Krucoff M, Spirito A, Baber U, Sartori S, Angiolillo DJ, Briguori C, Cohen DJ, Collier T, Dangas G, Dudek D, Escaned J, Gibson CM, Han Y-L, Huber K, Kastrati A, Kaul U, Kornowski R, Kunadian V, Vogel B, Mehta SR, Moliterno D, Sardella G, Shlofmitz RA, Sharma S, Steg PG, Pocock S, Mehran R. Ticagrelor with or without aspirin following percutaneous coronary intervention in high-risk patients with concomitant peripheral artery disease: A subgroup analysis of the TWILIGHT randomized clinical trial. American Heart Journal 2024, 272, 11-22.
  • Dirjayanto VJ, Martin-Ruiz C, Pompei G, Rubino F, Kunadian V. The association of inflammatory biomarkers and long-term clinical outcomes in older adults with non-ST elevation acute coronary syndrome. International Journal of Cardiology 2024, 409, 132177.
  • Nadarajah R, Ludman P, Laroche C, Appelman Y, Brugaletta S, Budaj A, Bueno H, Huber K, Kunadian V, Leonardi S, Lettino M, Milasinovic D, Gale CP. Sex-specific presentation, care, and clinical events in individuals admitted with NSTEMI: the ACVC-EAPCI EORP NSTEMI registry of the European Society of Cardiology. European Heart Journal: Acute Cardiovascular Care 2024, 13(1), 36-45.
  • Nadarajah R, Ludman P, Laroche C, Appelman Y, Brugaletta S, Budaj A, Bueno H, Huber K, Kunadian V, Leonardi S, Lettino M, Milasinovic D, Clegg A, Gale CP. Presentation, care, coronary intervention and outcomes of patients with NSTEMI according to age: Insights from the international prospective ACVC-EAPCI EORP NSTEMI registry. Age and Ageing 2024, 53(8), afae179.
  • Teles RC, Van Belle E, Parma R, Tarantini G, Van Mieghem N, Mylotte D, Silva JD, O'Connor S, Sondegaard L, Luz A, Amat-Santos IJ, Arzamendi D, Blackman D, De Backer O, Kunadian V, Buchanan GL, MacCarthy P, Lurz P, Naber C, Chieffo A, Paradies V, Gilard M, Vincent F, Fraccaro C, Mehilli J, Giannini C, Silva B, Poliacikova P, Karam N, Veulemans V, Thiele H, Pilgrim T, van Wely M, James S, Schmidt MR, Uebing A, Ruck A, Ghanem A, Ghazzal Z, Joshi FR, Favero L, Hermanides R, Ninios V, Fovino LN, Nuis R-J, Deharo P, Kala P, Elbaz-Greener G, Tchetche D, Agricola E, Thielmann M, Donal E, Bonaros N, Droogmans S, Czerny M, Baumbach A, Barbato E, Dudek D. Percutaneous Valvular and Structural Heart Disease Interventions. 2024 Core Curriculum of the European Association of Percutaneous Cardiovascular Interventions (EAPCI) of the ESC in collaboration with the European Association of Cardiovascular Imaging (EACVI) and the Cardiovascular Surgery Working Group (WG CVS) of the European Society of Cardiology. EuroIntervention 2024, 20(22), 1370-1379.
  • Mankerious N, Toelg R, Vogel B, Sartori S, Angiolillo DJ, Vranckx P, Feng Y, de la Torre Hernandez JM, Krucoff MW, Bhatt DL, Spirito A, Cao D, Chehab BM, Kunadian V, Maksoud A, Picon H, Sardella G, Thiele H, Varenne O, Windecker S, Richardt G, Valgimigli M, Mehran R. One-Month Versus Three-Month Dual-Antiplatelet Therapy in High Bleeding Risk Patients With Chronic Kidney Disease. American Journal of Cardiology 2024, 225, 25-34.
  • Maurina M, Pivato CA, Kunadian V, Testa L, Briguori C, Pacchioni A, Latini AC, Cesani N, Piccolo R, Musto C, Sardella G, Indolfi C, Regazzoli D, Paradies V, Stefanini G. One-month DAPT after biodegradable-polymer everolimus-eluting stent implantation in women at high-bleeding risk: Insights from the POEM trial. Catheterization and Cardiovascular Interventions 2024, 4(4), oeae068.
  • Cao D, Vranckx P, Valgimigli M, Sartori S, Angiolillo DJ, Bangalore S, Bhatt DL, Feng Y, Ge J, Hermiller J, Makkar RR, Neumann F-J, Saito S, Picon H, Toelg R, Maksoud A, Chehab BM, Choi JW, Campo G, De la Torre Hernandez JM, Krucoff MW, Kunadian V, Sardella G, Spirito A, Thiele H, Varenne O, Vogel B, Zhou Y, Windecker S, Mehran R. One- versus three-month dual antiplatelet therapy in high bleeding risk patients undergoing percutaneous coronary intervention for non-ST-segment elevation acute coronary syndromes. EuroIntervention 2024, 20(10), e630-e642.
  • Rubino F, Pompei G, Mills GB, Kotanidis CP, Laudani C, Bendz B, Berg ES, Hildick-Smith D, Hirlekar G, Morici N, Myat A, Tegn N, Sanchis Fores J, Savonitto S, De Servi S, Kunadian V. Older women with non-ST-elevation acute coronary syndrome undergoing invasive or conservative management: an individual patient data meta-analysis. European Heart Journal Open 2024, 4(6), oeae093.
  • Pompei G, Ganzorig N, Kotanidis CP, Alkhalil M, Collet C, Sinha A, Perera D, Beltrame J, Kunadian V. Novel diagnostic approaches and management of coronary microvascular dysfunction. American Journal of Preventive Cardiology 2024, 19, 100712.
  • Kelham M, Vyas R, Ramaseshan R, Rathod K, de Winter RJ, de Winter RW, Bendz B, Thiele H, Hirlekar G, Morici N, Myat A, Michalis LK, Sanchis J, Kunadian V, Berry C, Mathur A, Jones DA. Non-ST-elevation acute coronary syndromes with previous coronary artery bypass grafting: a meta-analysis of invasive vs. conservative management. European Heart Journal 2024, 45(27), 2380-2391.
  • Dirjayanto VJ, Pompei G, Rubino F, Biscaglia S, Campo G, Mihailidou A, den Ruijter H, Kunadian V. Non-invasive vascular measures as prognostic predictors for older patients with non-ST elevation acute coronary syndrome. Coronary Artery Disease 2024, 35(5), 368-381.
  • Rout A, Moumneh MB, Kalra K, Singh S, Garg A, Kunadian V, Biscaglia S, Alkhouli MA, Rymer JA, Batchelor WB, Nanna MG, Damluji AA. Invasive Versus Conservative Strategy in Older Adults ≥75 Years of Age With Non-ST-segment-Elevation Acute Coronary Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Journal of the American Heart Association 2024, 13(21), e036151.
  • Kunadian V, Mossop H, Shields C, Bardgett M, Watts P, Teare MD, Pritchard J, Adams-Hall J, Runnett C, Ripley DP, Carter J, Quigley J, Cooke J, Austin D, Murphy J, Kelly D, McGowan J, Veerasamy M, Felmeden D, Contractor H, Mutgi S, Irving J, Lindsay S, Galasko G, Lee K, Sultan A, Dastidar AG, Hussain S, Haq IUI, de Belder M, Denvir M, Flather M, Storey RF, Newby DE, Pocock SJ, Fox KAA. Invasive Treatment Strategy for Older Patients with Myocardial Infarction. New England Journal of Medicine 2024, 391(18), 1673-1684.
  • Rubino F, Brugaletta S, Mills G, Pompei G, Scarsini R, Ribichini F, Raber L, Kunadian V. Coronary Artery Plaque Phenotype and 5-Year Clinical Outcomes in Older Patients with Non-ST Elevation Acute Coronary Syndrome. Reviews in Cardiovascular Medicine 2024, 25(5), 168.
  • Tayal U, Pompei G, Wilkinson I, Adamson D, Sinha A, Hildick-Smith D, Cubbon R, Garbi M, Ingram TE, Colebourn CL, Camm CF, Guzik TJ, Anderson L, Page SP, Wicks E, Jenkins P, Rosen SD, Eftychiou S, Roberts E, Eftekhari H, Probert H, Cowie A, Thakkar R, Moore J, Berry C, Captur G, Deshpande A, Brown S, Malkin R, Harrison M, Lawson C, Ng GA, Kunadian V. Advancing the access to cardiovascular diagnosis and treatment among women with cardiovascular disease: A joint British Cardiovascular Societies' consensus document. Heart 2024, epub ahead of print.
  • Sardella G, Spirito A, Sartori S, Angiolillo DJ, Vranckx P, Hernandez JMDLT, Krucoff MW, Bangalore S, Bhatt DL, Campo G, Cao D, Chehab BM, Choi JW, Feng Y, Ge J, Godfrey K, Hermiller J, Kunadian V, Makkar RR, Maksoud A, Neumann F-J, Picon H, Saito S, Thiele H, Toelg R, Varenne O, Vogel B, Zhou Y, Valgimigli M, Windecker S, Mehran R. 1- Versus 3-Month DAPT in Older Patients at a High Bleeding Risk Undergoing PCI: Insights from the XIENCE Short DAPT Global Program. American Journal of Cardiology 2024, 214, 94-104.
  • Navarese EP, Landi A, Oliva A, Piccolo R, Aboyans V, Angiolillo D, Atar D, Capodanno D, Fox KAA, Halvorsen S, James S, Juni P, Kunadian V, Leonardi S, Mehran R, Montalescot G, Niebauer J, Price S, Storey RF, Voller H, Vranckx P, Windecker S, Valgimigli M. Within and beyond 12-month efficacy and safety of antithrombotic strategies in patients with established coronary artery disease: two companion network meta-analyses of the 2022 joint clinical consensus statement of the European Association of Percutaneous Cardiovascular Interventions (EAPCI), European Association for Acute CardioVascular Care (ACVC), and European Association of Preventive Cardiology (EAPC). European Heart Journal. Cardiovascular Pharmacotherapy 2023, 9(3), 271-290.
  • Lawless M, Appelman Y, Beltrame JF, Navarese EP, Ratcovich H, Wilkinson C, Kunadian V. Sex differences in treatment and outcomes amongst myocardial infarction patients presenting with and without obstructive coronary arteries: a prospective multicentre study. European Heart Journal Open 2023, 3(2).
  • Omboni S, Khan NA, Kunadian V, Olszanecka A, Schutte AE, Mihailidou AS. Sex Differences in Ambulatory Blood Pressure Levels and Subtypes in a Large Italian Community Cohort. Hypertension 2023, 80(7), 1417-1426.
  • Lawless M, Brown S, Kunadian V. Raising awareness about cardiovascular disease in women. European Heart Journal 2023, 44(33), 3110-3112.
  • Nadarajah R, Ludman P, Laroche C, Appelman Y, Brugaletta S, Budaj A, Bueno H, Huber K, Kunadian V, Leonardi S, Lettino M, Milasinovic D, Gale CP. Presentation, care, and outcomes of patients with NSTEMI according to World Bank country income classification: The ACVC-EAPCI EORP NSTEMI Registry of the European Society of Cardiology. European Heart Journal - Quality of Care and Clinical Outcomes 2023, 9(6), 552-563.
  • Charman SJ, Blain AP, Trenell MI, Jakovljevic DG, Kunadian V. Physical activity, inactivity and sleep in older patients with coronary artery disease following percutaneous coronary intervention: a longitudinal, observational study. Coronary Artery Disease 2023, 34(6), 441-447.
  • Buchanan GL, Paradies V, Karam N, Holmvang L, Mamas MA, Mehilli J, Capodanno D, Capranzano P, Appelman Y, Manzo-Silberman S, Kunadian V, Mauri J, Shuepke S, Petronio AS, Kaluzna-Oleksy M, Gilard M, Morice MC, Barbato E, Dudek D, Chieffo A. Overcoming professional barriers encountered by women in interventional cardiology: an EAPCI statement. European Heart Journal 2023, 44(15), 1301-1312.
  • Berry C, Kramer CM, Kunadian V, Patel TR, Villines T, Kwong RY, Raharjo DE. Great Debate: Computed tomography coronary angiography should be the initial diagnostic test in suspected angina. European Heart Journal 2023, 44(26), 2366-2375.
  • Angiolillo DJ, Cao D, Sartori S, Baber U, Dangas G, Zhang Z, Vogel B, Kunadian V, Briguori C, Cohen DJ, Collier T, Dudek D, Gibson M, Gil R, Huber K, Kaul U, Kornowski R, Krucoff MW, Ielasi A, Stefanini GG, Pivato CA, Mehta S, Moliterno DJ, Ohman EM, Escaned J, Sardella G, Sharma SK, Shlofmitz R, Weisz G, Witzenbichler B, Steg PG, Pocock S, Mehran R. Dyspnea-Related Ticagrelor Discontinuation After Percutaneous Coronary Intervention. JACC: Cardiovascular Interventions 2023, 16(20), 2514-2524.
  • Lawless M, Damluji A, Dirjayanto VJ, Mills G, Pompei G, Rubino F, Kunadian V. Differences in treatment and clinical outcomes in patients aged ≥75 years compared with those aged ≤74 years following acute coronary syndromes: a prospective multicentre study. Open Heart 2023, 10(2), e002418.
  • Oqab Z, Kunadian V, Wood DA, Storey RF, Rao SV, Mehran R, Pinilla-Echeverri N, Mani T, Boone RH, Kassam S, Bossard M, Mansour S, Ball W, Sibbald M, Valettas N, Moreno R, Steg PG, Cairns JA, Mehta SR. Complete Revascularization Versus Culprit-Lesion-Only PCI in STEMI Patients With Diabetes and Multivessel Coronary Artery Disease: Results From the COMPLETE Trial. Circulation: Cardiovascular Interventions 2023, 16(9), e012867.
  • Baber U, Spirito A, Sartori S, Angiolillo DJ, Briguori C, Cohen DJ, Collier T, Dangas G, Dudek D, Escaned J, Gibson CM, Han Y-L, Huber K, Kastrati A, Kaul U, Kornowski R, Krucoff M, Kunadian V, Vogel B, Mehta SR, Moliterno D, Sardella G, Shlofmitz RA, Sharma S, Steg PG, Pocock S, Mehran R. Clinically Driven Revascularization in High-Risk Patients Treated With Ticagrelor Monotherapy After PCI: Insights from the Randomized TWILIGHT Trial. American Journal of Cardiology 2023, 208, 16-24.
  • Kuzemczak M, Lipiecki J, Jeyalan V, Farhat H, Kleczynski P, Legutko J, Minten L, Bennett J, Poels E, Dens J, Spyridopoulos I, Kunadian V, Pawlowski T, Gil R, Egred M, Zaman A, Alkhalil M. Clinical outcomes of coronary intravascular lithotripsy in patients with stent failure (COIL registry). International Journal of Cardiology 2023, 391, 131274.
  • Mendieta G, Mehta S, Baber U, Angiolillo DJ, Briguori C, Cohen D, Collier T, Dangas G, Dudek D, Escaned J, Gil R, Vogel B, Cao D, Spirito A, Huber K, Kastrati A, Kaul U, Kornowski R, Krucoff MW, Kunadian V, Moliterno DJ, Ohman EM, Sardella G, Sartori S, Sharma S, Shlofmitz R, Steg PG, Han Y-L, Pocock S, Gibson CM, Mehran R. Bleeding and Ischemic Risks of Ticagrelor Monotherapy After Coronary Interventions. Journal of the American College of Cardiology 2023, 82(8), 687-700.
  • Spirito A, Valgimigli M, Cao D, Baber U, Mehta SR, Gibson CM, Steg GP, Sharma SK, Goel R, Huber K, Kunadian V, Escaned J, Franzone A, Yaling H, Collier T, Kaul U, Kornowski R, Krucoff M, Moliterno D, Sartori S, Owen R, Zhang Z, Dangas GD, Kastrati A, Angiolillo DJ, Cohen DJ, Vranckx P, Windecker S, Pocock S, Mehran R. Biolimus-eluting vs. other limus-eluting stents in NSTE-ACS: A pooled analysis of GLASSY and TWILIGHT. International Journal of Cardiology 2023, 383, 24-32.
  • Valgimigli M, Aboyans V, Angiolillo D, Atar D, Capodanno D, Halvorsen S, James S, Juni P, Kunadian V, Landi A, Leonardi S, Mehran R, Montalescot G, Navarese EP, Niebauer J, Oliva A, Piccolo R, Price S, Storey RF, Voller H, Vranckx P, Windecker S, Fox KAA. Antithrombotic treatment strategies in patients with established coronary atherosclerotic disease. European Heart Journal - Cardiovascular Pharmacotherapy 2023, 9(5), 462-496.
  • Beska B, Ratcovich H, Bagnall A, Burrell A, Edwards R, Egred M, Jordan R, Khan A, Mills GB, Morrison E, Raharjo DE, Singh F, Wilkinson C, Zaman A, Kunadian V. Angiographic and Procedural Characteristics in Frail Older Patients with Non-ST Elevation Acute Coronary Syndrome. Interventional Cardiology: Reviews, Research, Resources 2023, 18, e04.
  • Valgimigli M, Spirito A, Sartori S, Angiolillo DJ, Vranckx P, de la Torre Hernandez JM, Krucoff MW, Bangalore S, Bhatt DL, Campo G, Cao D, Chehab BM, Choi JW, Feng Y, Ge J, Hermiller J, Kunadian V, Lupo S, Makkar RR, Maksoud A, Neumann F-J, Picon H, Saito S, Sardella G, Thiele H, Toelg R, Varenne O, Vogel B, Zhou Y, Windecker S, Mehran R. 1- or 3-Month DAPT in Patients With HBR With or Without Oral Anticoagulant Therapy After PCI. JACC: Cardiovascular Interventions 2023, 16(20), 2498-2510.
  • Sardella G, Beerkens FJ, Dangas G, Cao D, Baber U, Sartori S, Cohen DJ, Briguori C, Gil R, Nicolas J, Zhang Z, Dudek D, Kunadian V, Kornowski R, Weisz G, Claessen B, Marx S, Escaned J, Huber K, Collier T, Moliterno DJ, Ohman EM, Krucoff MW, Kastrati A, Steg PG, Angiolillo DJ, Mehta S, Shlofmitz R, Sharma S, Pocock S, Gibson CM, Mehran R. Ticagrelor with and without aspirin in patients with a prior coronary artery bypass graft undergoing percutaneous coronary intervention: the TWILIGHT-CABG study. EuroIntervention : Journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 2022, 18(11), e897-e909.
  • Chiarito M, Baber U, Cao D, Sharma SK, Dangas G, Angiolillo DJ, Briguori C, Cohen DJ, Dudek D, Dzavik V, Escaned J, Gil R, Hamm CW, Henry T, Huber K, Kastrati A, Kaul U, Kornowski R, Krucoff M, Kunadian V, Mehta SR, Moliterno D, Ohman EM, Oldroyd K, Sardella G, Zhongjie Z, Sartori S, Stefanini G, Shlofmitz R, Steg PG, Weisz G, Witzenbichler B, Han Y-L, Pocock S, Gibson CM, Mehran R. Ticagrelor Monotherapy After PCI in High-Risk Patients With Prior MI: A Prespecified TWILIGHT Substudy. JACC: Cardiovascular Interventions 2022, 15(3), 282-293.
  • Kunadian V. The ongoing conundrum of the best care for patients presenting with non-ST-segment elevation acute coronary syndrome. EuroIntervention 2022, 18(7), 531-533.
  • Ratcovich H, Alkhalil M, Beska B, Holmvang L, Lawless M, Gede Dennis Sukadana I, Wilkinson C, Kunadian V. Sex differences in long-term outcomes in older adults undergoing invasive treatment for non-ST elevation acute coronary syndrome: An ICON-1 sub-study. IJC Heart and Vasculature 2022, 42, 101118.
  • Mills GB, Adams-Hall J, Beska B, Kirkup E, Raharjo DE, Veerasamy M, Wilkinson C, Kunadian V. Is the contemporary care of the older person with acute coronary syndrome evidence-based?. European Heart Journal Open 2022, 2(1), oeab044.
  • Beska B, Mills GB, Ratcovich H, Wilkinson C, Damluji AA, Kunadian V. Impact of multimorbidity on long-term outcomes in older adults with non-ST elevation acute coronary syndrome in the North East of England: a multi-centre cohort study of patients undergoing invasive care. BMJ Open 2022, 12(7), e061830.
  • MacGowan GA, McDiarmid A, Jansen K, Coats L, Crossland D, Woods A, Kunadian V, Shah A, Schueler S, Parry G. Gender differences in the assessment, decision-making and outcomes for ventricular assist devices and heart transplantation: An analysis from a UK transplant center. Clinical Transplantation 2022, 36(6), e14666.
  • Jackson J, Alkhalil M, Ratcovich H, Wilkinson C, Mehran R, Kunadian V. Evidence base for the management of women with non-ST elevation acute coronary syndrome. Heart 2022, 108(21), 1682-1689.
  • Batra G, Renlund H, Kunadian V, James SK, Storey RF, Steg PG, Katus HA, Harrington RA, Gibson CM, Budaj A, Siegbahn A, Wallentin L. Effects of early myocardial reperfusion and perfusion on myocardial necrosis/dysfunction and inflammation in patients with ST-segment and non-ST-segment elevation acute coronary syndrome: Results from the PLATelet inhibition and patients Outcomes (PLATO) trial. European Heart Journal: Acute Cardiovascular Care 2022, 11(4), 336-349.
  • Mehta SR, Wang J, Wood DA, Spertus JA, Cohen DJ, Mehran R, Storey RF, Steg PG, Pinilla-Echeverri N, Sheth T, Bainey KR, Bangalore S, Cantor WJ, Faxon DP, Feldman LJ, Jolly SS, Kunadian V, Lavi S, Lopez-Sendon J, Madan M, Moreno R, Rao SV, Rodes-Cabau J, Stankovic G, Bangdiwala SI, Cairns JA. Complete Revascularization vs Culprit Lesion-Only Percutaneous Coronary Intervention for Angina-Related Quality of Life in Patients With ST-Segment Elevation Myocardial Infarction: Results From the COMPLETE Randomized Clinical Trial. JAMA Cardiology 2022, 7(11), 1091-1099.
  • Kunadian V, Raharjo DE. Breaking down the barriers in the management of INOCA: how can we do better in the diagnosis of coronary vasomotor disorders?. EuroIntervention 2022, 17(15), 1201-1203.
  • Kunadian V, Baber U, Pivato CA, Cao D, Dangas G, Sartori S, Zhang Z, Angiolillo DJ, Briguori C, Cohen DJ, Collier T, Dudek D, Gibson M, Gil R, Huber K, Kaul U, Kornowski R, Krucoff MW, Dehghani P, Mehta S, Moliterno DJ, Ohman EM, Escaned J, Sardella G, Sharma SK, Shlofmitz R, Weisz G, Witzenbichler B, Dzavik V, Gurbel P, Hamm CW, Henry T, Kastrati A, Marx SO, Oldroyd K, Steg PG, Pocock S, Mehran R. Bleeding and Ischemic Outcomes With Ticagrelor Monotherapy According to Body Mass Index. JACC: Cardiovascular Interventions 2022, 15(19), 1948-1960.
  • van Diemen J, Verdonk P, Chieffo A, Regar E, Mauri F, Kunadian V, Sharma G, Mehran R, Appelman Y. The importance of achieving sex- and gender-based equity in clinical trials: a call to action. European Heart Journal 2021, 42(31), 2990-2994.
  • Vogel B, Baber U, Cohen DJ, Sartori S, Sharma SK, Angiolillo DJ, Farhan S, Goel R, Zhang Z, Briguori C, Collier T, Dangas G, Dudek D, Escaned J, Gil R, Han Y-L, Kaul U, Kornowski R, Krucoff MW, Kunadian V, Mehta SR, Moliterno D, Ohman EM, Sardella G, Witzenbichler B, Gibson CM, Pocock S, Huber K, Mehran R. Sex Differences among Patients with High Risk Receiving Ticagrelor with or without Aspirin after Percutaneous Coronary Intervention: A Subgroup Analysis of the TWILIGHT Randomized Clinical Trial. JAMA Cardiology 2021, 65, 226-233.
  • Bulluck H, Paradies V, Barbato E, Baumbach A, Botker HE, Capodanno D, De Caterina R, Cavallini C, Davidson SM, Feldman DN, Ferdinandy P, Gili S, Gyongyosi M, Kunadian V, Ooi S-Y, Madonna R, Marber M, Mehran R, Ndrepepa G, Perrino C, Schupke S, Silvain J, Sluijter JPG, Tarantini G, Toth GG, Van Laake LW, Von Birgelen C, Zeitouni M, Jaffe AS, Thygesen K, Hausenloy DJ. Prognostically relevant periprocedural myocardial injury and infarction associated with percutaneous coronary interventions: A Consensus Document of the ESC Working Group on Cellular Biology of the Heart and European Association of Percutaneous Cardiovascular Interventions (EAPCI). European Heart Journal 2021, 42(27), 2630-2642.
  • Beska B, Raharjo DE, Kunadian V. Novel drug-eluting stents to improve coronary endothelial and microvascular function in STEMI patients? / Nuevos stents farmacoactivos para mejorar la función endotelial y microvascular coronaria en el IAMCEST. Revista Española de Cardiología 2021, 74(12), 1004-1006.
  • Angiolillo DJ, Cao D, Baber U, Sartori S, Zhang Z, Dangas G, Mehta S, Briguori C, Cohen DJ, Collier T, Dudek D, Escaned J, Gibson CM, Gil R, Huber K, Kaul U, Kornowski R, Krucoff MW, Kunadian V, Moliterno DJ, Ohman EM, Oldroyd K, Sardella G, Sharma SK, Shlofmitz R, Weisz G, Witzenbichler B, Pocock S, Mehran R. Impact of Age on the Safety and Efficacy of Ticagrelor Monotherapy in Patients Undergoing PCI. JACC: Cardiovascular Interventions 2021, 14(13), 1434-1446.
  • Chung KJNC, Wilkinson C, Veerasamy M, Kunadian V. Frailty scores and their utility in older patients with cardiovascular disease. Interventional Cardiology Review 2021, 16, e05.
  • Beska B, Coakley D, Macgowan G, Adams-Hall J, Wilkinson C, Kunadian V. Frailty and quality of life after invasive management for non-ST elevation acute coronary syndrome. Heart 2021, 108(3), 203-211.
  • Kunadian V, Chieffo A, Camici PG, Berry C, Escaned J, Maas AHEM, Prescott E, Karam N, Appelman Y, Fraccaro C, Buchanan GL, Manzo-Silberman S, Al-Lamee R, Regar E, Lansky A, Abbott JD, Badimon L, Duncker DJ, Mehran R, Capodanno D, Baumbach A. An EAPCI Expert Consensus Document on Ischaemia with Non-Obstructive Coronary Arteries in Collaboration with European Society of Cardiology Working Group on Coronary Pathophysiology & Microcirculation Endorsed by Coronary Vasomotor Disorders International Study Group. EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 2021, 16(13), 1049-1069.
  • Dangas G, Baber U, Sharma S, Giustino G, Mehta S, Cohen DJ, Angiolillo DJ, Sartori S, Chandiramani R, Briguori C, Dudek D, Escaned J, Huber K, Collier T, Kornowski R, Kunadian V, Kaul U, Oldroyd K, Sardella G, Shlofmitz R, Witzenbichler B, Ya-Ling H, Pocock S, Gibson CM, Mehran R. Ticagrelor With or Without Aspirin After Complex PCI. Journal of the American College of Cardiology 2020, 75(19), 2414-2424.
  • Baber U, Dangas G, Angiolillo DJ, Cohen DJ, Sharma SK, Nicolas J, Briguori C, Cha JY, Collier T, Dudek D, Džavik V, Escaned J, Gil R, Gurbel P, Hamm CW, Henry T, Huber K, Kastrati A, Kaul U, Kornowski R, Krucoff M, Kunadian V, Marx SO, Mehta S, Moliterno D, Ohman EM, Oldroyd K, Sardella G, Sartori S, Shlofmitz R, Steg PG, Weisz G, Witzenbichler B, Han Y-L, Pocock S, Gibson CM, Mehran R. Ticagrelor alone vs. ticagrelor plus aspirin following percutaneous coronary intervention in patients with non-ST-segment elevation acute coronary syndromes: TWILIGHT-ACS. European Heart Journal 2020, 41(37), 3533-3545.
  • Chan D, Martin-Ruiz C, Saretzki G, Neely D, Qiu W, Kunadian V. The association of telomere length and telomerase activity with adverse outcomes in older patients with non-ST-elevation acute coronary syndrome. PLoS ONE 2020, 15(1), e0227616.
  • Khaing PH, Buchanan GL, Kunadian V. Diagnostic angiograms and percutaneous coronary interventions in pregnancy. Interventional Cardiology Review 2020, 15, e04.
  • Wilkinson C, Wu J, Searle S, Todd O, Hall M, Kunadian V, Clegg A, Rockwood K, Gale CP. Clinical outcomes in patients with atrial fibrillation and frailty: insights from the ENGAGE AF-TIMI 48 trial. BMC Medicine 2020, 18(1), 401.
  • Vinogradov R, Boag C, Murphy P, McGeeney D, Kunadian V, Robson SC. Aspirin non-response in pregnant women at increased risk of pre-eclampsia. European Journal of Obstetrics and Gynecology and Reproductive Biology 2020, 254, 292-297.
  • Kunadian V, Chieffo A, Camici PG, Berry C, Escaned J, Maas AHEM, Prescott E, Karam N, Appelman Y, Fraccaro C, Buchanan GL, Manzo-Silberman S, Al-Lamee R, Regar E, Lansky A, Abbott JD, Badimon L, Duncker DJ, Mehran R, Capodanno D, Baumbach A. An EAPCI Expert Consensus Document on Ischaemia with Non-Obstructive Coronary Arteries in Collaboration with European Society of Cardiology Working Group on Coronary Pathophysiology & Microcirculation Endorsed by Coronary Vasomotor Disorders International Study Group. European Heart Journal 2020, 41(37), 3504-3520.
  • Wood DA, Cairns JA, Wang J, Mehran R, Storey RF, Nguyen H, Meeks B, Kunadian V, Tanguay J-F, Kim H-H, Cheema A, Deghani P, Natarajan MK, Jolly SS, Amerena J, Keltai M, James S, Hlinomaz O, Niemela K, AlHabib K, Lewis BS, Nguyen M, Sarma J, Dzavik V, Della Siega A, Mehta SR. Timing of Staged Nonculprit Artery Revascularization in Patients With ST-Segment Elevation Myocardial Infarction: COMPLETE Trial. Journal of the American College of Cardiology 2019, 74(22), 2713-2723.
  • Mehran R, Barber U, Sharma SK, Cohen DJ, Angiolillo DJ, Briguori C, Cha JY, Collier T, Dangas G, Dudek D, Džavík V, Escaned J, Gil R, Gurbel P, Hamm CW, Henry T, Huber K, Kastrati A, Kaul U, Kornowski R, Krucoff M, Kunadian V, Marx SO, Mehta SR, Moliterno D, Ohman EM, Oldroyd K, Sardella G, Sartori S, Shlofmitz R, Steg PG, Weisz G, Witzenbichler B, Han YL, Pocock S, Gibson CM. Ticagrelor with or without Aspirin in High-Risk Patients after PCI. New England Journal of Medicine 2019, 381(21), 2032-2042.
  • Beska B, Chan D, Gu S, Qiu W, Mossop H, Neely D, Kunadian V. The association between Vitamin D status and clinical events in high-risk older patients with non-ST elevation acute coronary syndrome undergoing invasive management. PLoS ONE 2019, 14(6), e0217476.
  • Vogel B, Goel R, Kunadian V, Kalkman DN, Chieffo A, Appelman Y, Mehran R. Residual angina in female patients after coronary revascularization. International Journal of Cardiology 2019, 286, 208-213.
  • Storey RF, Gurbel PA, ten Berg J, Bernaud C, Dangas GD, Frenoux JM, Gorog DA, Hmissi A, Kunadian V, James S, Tanguay JF, Tran H, Trenk D, Ufer M, Van der Harst P, Van't Hof A, Angiolillo DJ. Pharmacodynamics, pharmacokinetics, and safety of single-dose subcutaneous administration of selatogrel, a novel P2Y₁₂receptor antagonist, in patients with chronic coronary syndromes. European Heart Journal 2019, 41(33), 3132-3140.
  • Gu SZ, Qiu W, Batty JA, Sinclair H, Veerasamy M, Brugaletta S, Neely D, Ford G, Calvert PA, Mintz GS, Kunadian V. Coronary artery lesion phenotype in frail older patients with non-ST-elevation acute coronary syndrome undergoing invasive care. EuroIntervention 2019, 15(3), e261-e268.
  • Gu SZ, Beska B, Chan D, Neely D, Batty JA, Adams-Hall J, Mossop H, Qiu W, Kunadian V. Cognitive Decline in Older Patients With Non-ST Elevation Acute Coronary Syndrome. Journal of the American Heart Association 2019, 8(4), e011218.
  • Johnson TW, Raber L, di Mario C, Bourantas C, Jia H, Mattesini A, Gonzalo N, de la Torre Hernandez JM, Prati F, Koskinas K, Joner M, Radu MD, Erlinge D, Regar E, Kunadian V, Maehara A, Byrne RA, Capodanno D, Akasaka T, Wijns W, Mintz GS, Guagliumi G. Clinical use of intracoronary imaging. Part 2: acute coronary syndromes, ambiguous coronary angiography findings, and guiding interventional decision-making: an expert consensus document of the European Association of Percutaneous Cardiovascular Interventions. European Heart Journal 2019, 40(31), 2566-2584.
  • Johnson TW, Raber L, DiMario C, Bourantas CV, Jia H, Mattesini A, Gonzalo N, de la Torre Hernandez JM, Prati F, Koskinas KC, Joner M, Radu MD, Erlinge D, Regar E, Kunadian V, Maehara A, Byrne RA, Capodanno D, Akasaka T, Wijns W, Mintz GS, Guagliumi G. Clinical use of intracoronary imaging. Part 2: acute coronary syndromes, ambiguous coronary angiography findings, and guiding interventional decision-making: an expert consensus document of the European Association of Percutaneous Cardiovascular Interventions. Eurointervention 2019, 15(5), 434-451.
  • Kalarus Z, Svendsen J, Capodanno D, Dan GA, De Maria E, Gorenek B, Jedrzejczyk-Patej E, Mazurek M, Podolecki T, Sticherling C, Tfelt-Hansen J, Traykov V, Lip GYH, Fauchier L, Boriani G, Mansourati J, Blomstrom-Lundqvist C, Mairesse GH, Rubboli A, Deneke T, Dagres N, Steen T, Ahrens I, Kunadian V, Berti S. Cardiac arrhythmias in the emergency settings of acute coronary syndrome and revascularization: an European Heart Rhythm Association (EHRA) consensus document, endorsed by the European Association of Percutaneous Cardiovascular Interventions (EAPCI), and European Acute Cardiovascular Care Association (ACCA). Europace 2019, 21(10), 1603-1604.
  • Kunadian V, Wilson N, Stocken D, Hani A, McColl E, Burns G, Howe N, Fisher A, De Soyza A. Antiplatelet therapy in the primary prevention of cardiovascular diseasein patients with chronic obstructive pulmonary disease: a randomised controlled proof-of-concept trial. ERJ Open Research 2019, 5(3).
  • Chieffo A, Buchanan GL, Mehilli J, Capodanno D, Kunadian V, Petronio AS, Mikhail GW, Capranzano P, Gonzal N, Karam N, Manzo-Silberman S, Schüpke S, Byrne RA, Capretti G, Appelman Y, Morice MC, Presbitero P, Radu M, Mauri J. Percutaneous Coronary and Structural Interventions in Women. A Position Statement from the EAPCI Women Committee. EuroIntervention 2018, 14, e1227-e1235.
  • Batty J, Qiu W, Gu S, Sinclair H, Veerasamy M, Beska B, Neely D, Ford G, Kunadian V. One-year clinical outcomes in older patients with non-ST elevation acute coronary syndrome undergoing coronary angiography: An analysis of the ICON1 study. International Journal of Cardiology 2018, 274, 45-51.
  • Kunadian V, Chan D, Ali H, Wilkinson N, Howe N, McColl E, Thornton J, von Wilamowitz-Moellendorff A, Holstein EM, Burns G, Fisher A, Stocken D, De Soyza A. Antiplatelet therapy in the primary prevention of cardiovascular disease in patients with chronicobstructive pulmonary disease: protocol of a randomised controlled proof-of-concept trial (APPLE COPD-ICON 2). BMJ Open 2018, 8, e020713.
  • Kunadian V, Qiu WL, Lagerqvist B, Johnston N, Sinclair H, Tan Y, Ludman P, James S, Sarno G. Gender Differences in Outcomes and Predictors of All-Cause Mortality After Percutaneous Coronary Intervention (Data from United Kingdom and Sweden). American Journal of Cardiology 2017, 119(2), 210-216.
  • Charman SJ, van Hees VT, Quinn L, Dunford JR, Bawamia B, Veerasamy M, Trenell MI, Jakovljevic DG, Kunadian V. The effect of percutaneous coronary intervention on habitual physical activity in older patients. BMC Cardiovascular Disorders 2016, 16(1), 248.
  • Nazir SA, McCann GP, Greenwood JP, Kunadian V, Khan JN, Mahmoud IZ, Blackman DJ, Been M, Abrams KR, Shipley L, Wilcox R, Adgey AA, Gershlick AH. Strategies to attenuate micro-vascular obstruction during P-PCI: the randomized reperfusion facilitated by local adjunctive therapy in ST-elevation myocardial infarction trial. European Heart Journal 2016, 37(24), 1910-1919.
  • Capranzano P, Kunadian V, Mauri J, Petronio AS, Salvatella N, Appelman Y, Gilard M, Mikhail GW, Schüpke S, Radu MD, Vaquerizo B, Presbitero P, Morice MC, Mehilli J. Motivations for and barriers to choosing an interventional cardiology career path: results from the EAPCI Women Committee worldwide survey. EuroIntervention 2016, 12(1), 53-59.
  • Parikh JD, Hollingsworth KG, Kunadian V, Blamire AM, MacGowan GA. Measurement of pulse wave velocity in normal ageing: comparison of Vicorder and magnetic resonance phase contrast imaging. BMC Cardiovascular Disorders 2016, 16, 50.
  • Sinclair H, Batty JA, Qiu W, Kunadian V. Engaging older patients in cardiovascular research: Observational analysis of the ICON-1 study. Open Heart 2016, 3(2).
  • Fowkes R, Byrne M, Sinclair H, Tang E, Kunadian V. Coronary artery disease in patients with dementia. Coronary Artery Disease 2016, 27(6), 511-520.
  • Kunadian V, Neely D, Sinclair H, Batty JA, Veerasamy M, Ford GA, Qiu W. A Study to Improve Cardiovascular Outcomes in High-Risk Older PatieNts (ICON-1) with Acute Coronary Syndrome: Study Design and Protocol of a Prospective Observational Study. BMJ Open 2016, 6, e012091.
  • Sinclair H, Bourantas C, Bagnall A, Mintz GS, Kunadian V. OCT for the Identification of Vulnerable Plaque in Acute Coronary Syndrome. JACC-Cardiovascular Imaging 2015, 8(2), 198-209.
  • Kwok CS, Kontopantelis E, Kunadian V, Anderson S, Ratib K, Sperrin M, Zaman A, Ludman PF, De Belder MA, Nolan J, Mamas MA, Natl Inst Cardiovasc Outcomes Res, British Cardiovasc Intervention So. Effect of access site, gender, and indication on clinical outcomes after percutaneous coronary intervention: Insights from the British Cardiovascular Intervention Society (BCIS). American Heart Journal 2015, 170(1), 164-172.e5.
  • Nazir SA, Khan JN, Mahmoud IZ, Greenwood JP, Blackman DJ, Kunadian V, Been M, Abrams KR, Wilcox R, Adgey AAJ, McCann GP, Gershlick AH. The REFLO-STEMI trial comparing intracoronary adenosine, sodium nitroprusside and standard therapy for the attenuation of infarct size and microvascular obstruction during primary percutaneous coronary intervention: study protocol for a randomised controlled trial. Trials 2014, 15, 371.
  • Austin D, Yan AT, Spratt JC, Kunadian V, Edwards RJ, Egred M, Bagnall AJ. Patient characteristics associated with self-presentation, treatment delay and survival following primary percutaneous coronary intervention. European Heart Journal: Acute Cardiovascular Care 2014, 3(3), 214-222.
  • Kunadian V, Qiu WL, Ludman P, Redwood S, Curzen N, Stables R, Gunn J, Gershlick A, Natl Inst Cardiovasc Outcomes Res. Outcomes in Patients With Cardiogenic Shock Following Percutaneous Coronary Intervention in the Contemporary Era An Analysis From the BCIS Database (British Cardiovascular Intervention Society). JACC: Cardiovascular Interventions 2014, 7(12), 1374-1385.
  • Kunadian V, Bawamia B, Maznyczka A, Zaman A, Qiu W. Outcomes Following Primary Percutaneous Coronary Intervention in the Setting of Cardiac Arrest: A Registry Database Study. European Heart Journal: Acute Cardiovascular Care 2014, 1-10.
  • Kunadian V, Mehran R, Lincoff AM, Feit F, Manoukian SV, Hamon M, Cox DA, Dangas GD, Stone GW. Effect of Anemia on Frequency of Short- and Long-Term Clinical Events in Acute Coronary Syndromes (from the Acute Catheterization and Urgent Intervention Triage Strategy Trial). American Journal of Cardiology 2014, 114(12), 1823-1829.
  • Kunadian V, Giugliano R, Newby LK, Zorkun C, Guo J, Bagai A, Montalescot G, Braunwald E, Califf RM, Van de Werf F, Armstrong PW, Harrington R, Gibson CM. Angiographic Outcomes with Early Eptifibatide Therapy in Non-ST-Segment Elevation Acute Coronary Syndrome (From the EARLY ACS Trial). American Journal of Cardiology 2014, 113(8), 1297-1305.
  • Kunadian V, Qiu W, Bawamia B, Jamieson S, Zaman A. Primary PCI for ST Elevation Myocardial Infarction in patients with cardiogenic shock: Declining mortality with absence of gender difference. American Journal of Cardiology 2013. Submitted.
  • Kunadian V, Qiu WL, Bawamia B, Veerasamy M, Jamieson S, Zaman A. Gender Comparisons in Cardiogenic Shock During ST Elevation Myocardial Infarction Treated by Primary Percutaneous Coronary Intervention. American Journal of Cardiology 2013, 112(5), 636-641.
  • Navarese EP, Austin D, Gurbel PA, Andreotti F, Tantry U, James S, Buffon A, Kozinski M, Obonska K, Bliden K, Jeong YH, Kubica J, Kunadian V. Drug-coated balloons in treatment of in-stent restenosis: a meta-analysis of randomised controlled trials. Clinical Research in Cardiology 2013, 102(4), 279-287.
  • Kunadian V, Sinclair H, Sutton A, Dangas GD. Aspirin, Platelet P2Y12 Receptor Inhibitors, and Other Oral Antiplatelets: Comparative Pharmacology and Role in Elective PCI. Interventional Cardiology Clinics 2013, 2(4), 527-535.
  • Kunadian V, James S, Wojdyla D, Zorkun C, Wu J, Storey RF, Steg G, Katus H, Emanuelsson H, Horrow J, Maya H, Wallentin L, Harrington R, Gibson CM. Angiographic Outcomes in the PLATO Trial (Platelet Inhibition and Patient Outcomes). Journal of the American College of Cardiology: Cardiovascular Interventions 2013, 6(7), 671-683.
  • Kunadian V, James SK, Wojdyla DM, Zorkun C, Wu JH, Storey RF, Steg PG, Katus H, Emanuelsson H, Horrow J, Maya J, Wallentin L, Harrington RA, Gibson M. Angiographic Outcomes in the PLATO Trial (Platelet Inhibition and Patient Outcomes). JACC: Cardiovascular Interventions 2013, 6(7), 671-683.
  • Noman A, Balasubramaniam K, Das R, Ang D, Kunadian V, Ivanauskiene T, Zaman AG. Admission Heart Rate Predicts Mortality Following Primary Percutaneous Coronary Intervention for ST-Elevation Myocardial Infarction: An Observational Study. Cardiovascular Therapeutics 2013, 31(6), 363-369.
  • Kunadian V, Gibson CM. Thrombolytics and Myocardial Infarction. Cardiovascular Therapeutics 2012, 30(2), e81-e88.
  • Bundhoo SS, Earp E, Ivanauskiene T, Kunadian V, Freeman P, Edwards R, Kinnaird TD, Zaman A, Anderson RA. Saphenous vein graft percutaneous coronary intervention via radial artery access: Safe and effective with reduced hospital length of stay. American Heart Journal 2012, 164(4), 468-472.
  • Kunadian V, Pugh A, Zaman AG, Qiu WL. Percutaneous coronary intervention among patients with left ventricular systolic dysfunction: a review and meta-analysis of 19 clinical studies. Coronary Artery Disease 2012, 23(7), 469-479.
  • Pride YB, Mohanavelu S, Zorkun C, Kunadian V, Giugliano RP, Newby LK, Braunwald E, Califf RM, Harrington R, Gibson CM. Association between Angiographic Complications and Clinical Outcomes among Patients with Acute Coronary Syndrome undergoing Percutaneous Coronary Intervention: An EARLY ACS Angiographic Substudy. Journal of the American College of Cardiology: Cardiovascular Interventions 2012, 5(9), 927-935.
  • Kunadian V, Zaman A, Spyridopoulos I, Qiu W. Sodium bicarbonate for the prevention of contrast induced nephropathy: A meta-analysis of published clinical trials. European Journal of Radiology 2011, 79(1), 48-55.
  • Best PJ, Skelding KA, Mehran R, Chieffo A, Kunadian V, Madan M, Mikhail GW, Mauri F, Takahashi S, Honye J, Hernández-Antolín R, Weiner BH. SCAI Consensus Document on Occupational Radiation Exposure to the Pregnant Cardiologist and Technical Personnel. Eurointervention 2011, 6(7), 866-874.
  • Best PJ, Skelding KA, Mehran R, Chieffo A, Kunadian V, Madan M, Mikhail GW, Mauri F, Takahashi S, Honye J, Hernández-Antolín R, Weiner BH. SCAI consensus document on occupational radiation exposure to the pregnant cardiologist and technical personnel. Catheterization and Cardiovascular Interventions 2011, 77(2), 232-241.
  • Best PJ, Skelding KA, Mehran R, Chieffo A, Kunadian V, Madan M, Mikhail GW, Mauri F, Takahashi S, Honye J, Hernández-Antolín R, Weiner BH. SCAI consensus document on occupational radiation exposure to the pregnant cardiologist and technical personnel. Heart, Lung & Circulation 2011, 20(2), 83-90.
  • Kunadian V, Zaman A, Qiu WL. Revascularization among patients with severe left ventricular dysfunction: a meta-analysis of observational studies. European Journal of Heart Failure 2011, 13(7), 773-784.
  • Kunadian V, Pride YB, Buris J, Ciaglo L, Morrow D, Gibson CM. Coronary Flow Reserve Varies Depending Upon the Location Within the Artery it is Assessed and the TIMI Myocardial Perfusion Grade: A PROTECT TIMI-30 Analysis. Journal of Thrombosis and Thrombolysis 2011, 32(4), 448-452.
  • Kunadian V, Harrigan C, Zorkun C, Palmer AM, Ogando KJ, Biller LH, Lord EE, Williams SP, Lew ME, Ciaglo LN, Buros JL, Marble SJ, Gibson WJ, Gibson CM. Use of the TIMI Frame Count in the Assessment of Coronary Artery Blood Flow and Microvascular Function Over the Past 15 years. Journal of Thrombosis and Thrombolysis 2009, 27(3), 316-328.
  • Lo TS, Nolan J, Fountzopoulos E, Behan M, Butler R, Hetherington SL, Vijayalakshmi K, Rajagopal R, Fraser D, Zaman A, Hildick-Smith D. Radial artery anomaly and its influence on transradial coronary procedural outcome. Heart 2009, 95(5), 410-415.
  • Gibson CM, Pride YB, Aylward PE, Col JJ, Goodman SG, Gulba D, Bergovec M, Kunadian V, Zorkun C, Buros JL, Murphy SA, Antman EM. Association of Non-Steroidal Anti-Inflammatory Drugs with Outcomes in Patients with ST-Segment Elevation Myocardial Infarction Treated with Fibrinolytic Therapy: An ExTRACT-TIMI 25 Analysis. Journal of Thrombosis and Thrombolysis 2009, 27(1), 11-17.
  • Kunadian V, Zorkun C, Gibson WJ, Nethala N, Harrigan C, Palmer AM, Ogando KJ, Biller LH, Lord EE, Williams SP, Lew ME, Ciaglo LN, Buros JL, Marble SJ, Gibson CM. Transfusion Associated Microchimerism: A Heretofore Little Recognized Complication Following Transfusion. Journal of Thrombosis and Thrombolysis 2008, 27(1), 57-67.
  • Thambyrajah J, Kunadian V, Graham RJ, Turley AJ, de Belder MA, Stewart MJ. Strain rate imaging pre- and post-percutaneous coronary intervention: a potential role in the objective detection of ischaemia in exercise stress echocardiography. European Journal of Echocardiography 2008, 9(5), 646-54.
  • Kunadian B, Kunadian V, Dunning J, Sutton AG, Muir DF, Wright RA, Hall JA, de Belder MA. Rescue angioplasty after failed fibrinolysis for acute myocardial infarction: predictors of a failed procedure and 1-year mortality. Catheterization and Cardiovascular Interventions 2008, 71(2), 138-145.
  • Gibson CM, Pride YB, Buros JL, Kunadian V, Southard MC, Harrigan CJ, Ciaglo LN, Sabatine MS, Cannon CP, Braunwald E. Relation of hyperemic epicardial flow to outcomes among patients with ST segment elevation myocardial infarction receiving fibrinolytic therapy. American Journal of Cardiology 2008, 101(9), 1232-1238.
  • Hobson AR, McKenzie DB, Kunadian V, Purcell I, Zaman A, Dawkins KD, Curzen N. Malignancy: An unrecognized risk factor for coronary stent thrombosis?. Journal of Invasive Cardiology 2008, 20(4), E120-E123.
  • Kunadian V, Griffiths A, Hasan A, O'Sullivan J. Late hazards after repair of coarctation of the aorta. British Medical Journal 2008, 336(7647), 772-773.
  • Kunadian V, Zorkun C, Williams SP, Biller LH, Palmer AM, Ogando KJ, Lew ME, Nethala N, Gibson WJ, Marble SJ, Buros JL, Gibson CM. Intracoronary Pharmacotherapy in the Management of Coronary Microvascular Dysfunction. Journal of Thrombosis and Thrombolysis 2008, 26(3), 234-242.
  • Kunadian V, De Belder MA. Angiographic and physiologic assessment of coronary flow and myocardial perfusion in the cardiac catheterization laboratory. Acute Cardiac Care 2008, 10(2), 69-78.
  • Kunadian B, Kunadian V, de Belder MA. Treatment of restenosis after bare-metal and drug-eluting stenting of an aorto-ostial lesion: challenges associated with excessive stent overhang. Journal of Cardiovascular Medicine (Hagerstown) 2007, 8(9), 744-747.
  • Kunadian B, Kunadian V, Dunning J, Sutton A, de Belder MA. Towards an understanding of the role of rescue angioplasty for failed fibrinolysis: comparison of the MERLIN, RESCUE and REACT trials. Journal of Invasive Cardiology 2007, 19(9), 359-368.
  • Kunadian V, Kunadian B, Whittaker VJ, Williams D, Wright RA, Sutton AG, Hall JA, de Belder MA. The impact of chronically diseased coronary arteries and stenting on the corrected TIMI frame count in elective coronary angiography and percutaneous coronary intervention procedures. Catheterization and Cardiovascular Interventions 2007, 70(5), 691-700.
  • Kunadian B, Kunadian V, Balasubramanian S, Dunning J. Should the tricuspid valve be replaced with a mechanical or biological valve?. Interactive Cardiovascular and Thoracic Surgery 2007, 6, 551-557.
  • Kunadian B, Kunadian V, Dunning J, Thornley AR, Sutton AG, Muir DF, Wright RA, Hall JA, de Belder MA. Should patients in cardiogenic shock undergo rescue angioplasty after failed fibrinolysis: comparison of primary versus rescue angioplasty in cardiogenic shock patients. Journal of Invasive Cardiology 2007, 19(5), 217-223.
  • Kunadian B, Kunadian V, Thornley AR, de Belder MA, Hunter S, Kendall S, Graham R, Stewart M, Thambyrajah J, Dunning J. Meta-analysis of valve hemodynamics and left ventricular mass regression for stentless versus stented aortic valves. Annals of Thoracic Surgery 2007, 84(1), 73-78.
  • Kunadian B, Dunning J, Kunadian V, Thornley AR, de Belder MA. Meta-analysis of randomized trials comparing anti-embolic devices with standard PCI for improving myocardial reperfusion in patients with acute myocardial infarction. Catheterization and Cardiovascular Interventions 2007, 69(4), 488-496.
  • Kunadian V, Kunadian B, Whittaker VJ, Wright RA, Hall JA, Sutton A, Muir D, de Belder MA. Intra-aortic counterpulsation does not improve coronary flow early after PCI in a high-risk group of patients: observations from a randomized trial to explore its mode of action. Journal of Invasive Cardiology 2007, 19(8), 339-346.
  • Kunadian V, Kunadian B, Whittaker VJ, Wright RA, Hall JA, Somasundram U, Stewart MJ, Sutton A, Davies A, de Belder MA. Impact of catheter sizes and intracoronary glyceryl trinitrate on the TIMI frame count when digital angiograms are acquired at lower frame rates during elective angiography and PCI. Acute Cardiac Care 2007, 9(4), 231-238.
  • Kunadian B, Sutton AGC, Vijayalakshmi K, Thornley AR, Gray JC, Grech ED, Hall JA, Harcombe AA, Wright RA, Smith RH, Murphy JJ, Shyam-Sundar A, Stewart MJ, Davies A, Linker NJ, de Belder MA. Early invasive versus conservative treatment in patients with failed fibrinolysis-no late survival benefit: The final analysis of the Middlesbrough Early Revascularisation to Limit Infarction (MERLIN) randomized trial. American Heart Journal 2007, 153(5), 763-771.
  • Kunadian V, Kunadian B, Wright RA, Hall JA, Stewart MJ, Davies A, Sutton A, de Belder MA. A prospective randomised controlled trial to determine the early and late reactions after the use of iopamidol 340 (Niopam) and iomeprol 350 (Iomeron) in cardiac catheterisation. European Journal of Radiology 2007, 61(2), 342-350.
  • Kunadian V, Kunadian B, Wright RA, Sutton AG, Hall JA, de Belder MA. Successful thrombus extraction with the Rescue thrombus management system during acute percutaneous coronary intervention improves flow but does not necessarily restore optimal myocardial tissue perfusion. Catheterization and Cardiovascular Interventions 2006, 67(6), 879-886.
  • Kunadian V, Whittaker VJ, Kunadian B, Graham J, Wright RA, Hall J, Sutton A, de Belder MA. Prospective, randomised, controlled trial to study the effect of intracoronary injection of verapamil and adenosine on coronary blood flow during percutaneous coronary intervention in patients with acute coronary syndromes. Heart 2006, 92(9), 1278-1284.
  • Kunadian V, Whittaker VJ, Sutton A, Campbell P, Wright RA, Hall JA, Harcombe AA, Linker NJ, Stewart MJ, Davies A, de Belder MA. A randomized trial of prophylactic antiarrhythmic agents (amiodarone and sotalol) in patients with atrial fibrillation for whom direct current cardioversion is planned. American Heart Journal 2006, 151(4), 863.e1-863.e6.
  • Kunadian V, Ashton VJ, Wright RA, Hall JA, Stewart MJ, Davies A, de Belder MA. Corrected TIMI frame count: applicability in modern digital catheter laboratories when different frame acquisition rates are used. Catheterization and Cardiovascular Interventions 2004, 63(4), 426-432.
  • Kunadian V, Williams D, Wright RA, Hall JA, Harcombe AA, Linker NJ, Stewart MJ, Davies A, de Belder MA. A prospective, randomized trial to determine the early and late reactions after the use of iopamidol 340 (Niopam) and iobitridol 350 (Xenetix) in cardiac catheterization. Journal of Invasive Cardiology 2004, 16(12), 707-711.

• Book Chapters

  • Gu SZ, Gamal A, Eggett C, Ali H, Zaman A, Edwards R, Kunadian V. Percutaneous Coronary Intervention for Left Ventricular Systolic Dysfunction. In: Myat, A; Clarke, S; Curzen, N; Windecker, S; Gurbel, P, ed. The Interventional Cardiology Training Manual. Cham: Springer, 2018, pp.263-274.
  • Beska B, Eggett C, Kunadian V. Mitral Valvuloplasty for Mitral Stenosis. In: Patrizia Presbitero, Julinda Mehilli, Anna Sonia Petronio, ed. Percutaneous Treatment of Cardiovascular Diseases in Women. Springer, 2016, pp.127-13.
  • Bawamia B, Sinclair H, Veerasamy M, Kunadian V. Interventional Management of Coronary Artery Disease: Acute Coronary Syndromes. In: PanVascular Medicine. Springer Berlin Heidelberg, 2015, pp.2071-2107.
  • Vlachojannis G, Kunadian V, Sweeny J, Mehran R. Antithrombotic therapy in non–ST-segment elevation acute coronary syndromes. In: Moliterno, D.J., Kristensen, S.D., De Caterina, R, ed. Therapeutic Advances in Thrombosis. Oxford: Blackwell Publishing Ltd, 2012, pp.205-212.

• Conference Proceedings (inc. Abstracts)

  • Varenhorst CV, Akerblom A, Renlund H, Kunadian V, James SK, Steg PG, Katus HA, Himmelmann A, Aylward P, Maurer G, Storey RF, Armstrong PW, Gibson M, Wallentin L. Successful reperfusion is associated with lower levels of markers of myocardial damage and dysfunction in ST-elevation but not in non-ST-elevation myocardial infarction: insights from the PLATO trial. In: ESC Congress 2016 (European Society of Cardiology). 2016, Rome, Italy: Oxford University Press.
  • Collins C, Kunadian V, James P, Robson S. Cardiovascular risk and vascular function after pregnancies complicated by pre-eclampsia and small for gestational age. In: RCOG World Congress. 2016, Birmingham, UK: Wiley-Blackwell Publishing Ltd.
  • Kunadian V, Batty J, Stone E, Okonkwo A. The full publication rate of abstracts presented at the British Cardiovascular Society Annual Conference remains high, comparing favourably with other cardiology annual scientific sessions worldwide. In: BCS Annual Conference: Hearts and Genes. 2015, Manchester, UK: BMJ Publishing Group.
  • Kunadian V, Veerasamy M, Sinclair H, Qiu WL, Das R, Ahmed J, Purcell I, Edwards R, Zaman A, Bagnall A. Major Adverse Cardiovascular Events at 30-days were not Significantly different between Frail and non-frail older ( ≥75 Years) Patients with non ST Elevation Acute Coronary Syndrome Managed by Invasive Strategy: An Analysis from the ICON1 Study. In: BCS Annual Conference: Hearts and Genes. 2015, Manchester, UK: BMJ Publishing Group.
  • Lima JAC, Sinclair H, Veerasamy M, Ang JJ, Qiu W, Neely D, Kunadian V. Increased parathyroid hormone level is associated with increased arterial stiffness and endothelial dysfunction in older patients with non-ST elevation acute coronary syndrome. In: ESC Congress 2015. 2015, London, UK: Oxford University Press.
  • Kunadian V, Veerasamy M, Sinclair H, Qiu WL. Frailty is Associated with Undiagnosed Early Cognitive Impairment in older patients (>= 75 years) with non-ST Elevation Acute Coronary Syndrome Managed by Invasive Strategy. In: BCS Annual Conference, 'Hearts and Genes'. 2015, Manchester, UK: BMJ Publishing Group.
  • Sinclair H, Veerasamy M, Teoh X, Lima JAC, Qiu W, Kunadian V. Frailty is associated with increased GRACE risk score in older patients with non-ST elevation acute coronary syndrome. In: ESC Congress 2015. 2015, London, UK: Oxford University Press.
  • Kunadian V, Veerasamy M, Sinclair H, Batty J, Sharifpour M, Lima J, Neely D, Martin-Ruiz C, Saretzki G. Association of Telomere Length and Telomerase Activity with Clinical Parameters in Older Patients Undergoing Invasive Management Of non-ST Elevation Acute Coronary Syndrome. In: BCS annual conference. 2015, Manchester, UK: BMJ Group.
  • Denton SJ, vanHees VT, Bawamia B, Veerasamy M, Quinn L, Dunford JR, Trenell MI, Jakovljevic DG, Kunadian V. Sedentary Behaviour and Physical Activity Among Older Patients Following Percutaneous Coronary Intervention Presented with Stable Angina versus Acute Coronary Syndrome. In: American Heart Association's 2014 Scientific Sessions and Resuscitation Science Symposium. 2014, Chicago, Illinois: American Heart Association , Inc.
  • Kunadian V, Qiu W, Ludman P, Redwood S, Curzen N, Stables R, Gunn J, Gershlick A. Outcomes in patients with cardiogenic shock following percutaneous coronary intervention in the contemporary era: an analysis from the british cardiovascular intervention society (BCIS) database. In: European Society of Cardiology Congress. 2014, Barcelona, Spain: Oxford University Press.
  • Veerasamy M, Sinclair H, Newton J, Kirkwood T, Kunadian V. Frailty is common among older patients referred for invasive treatment in the setting of non-ST elevation acute coronary syndrome. In: ESC Congress 2014. 2014, Barcelona, Spain: Oxford University Press.
  • Crittenden S, Coulson E, Kunadian V, Ng WF, Foster HE. Elevated Cardiovascular Disease Burden and Inflammatory Biomarker Levels in Adults with Juvenile Idiopathic Arthritis. In: 2014 ACR/ARHP Annual Meeting. 2014, Boston, MA: John Wiley & Sons, Inc.
  • Balasubramaniam K, Noman A, Das R, Kunadian V, Ivanauskiene T, Zaman A. Admission Heart Rate Predicts Mortality Following Primary Percutaneous Coronary Intervention for ST-Elevation Myocardial Infarction. In: British Cardiovascular Society Annual Conference. 2013, London, UK: BMJ Group.
  • Kunadian V, Veerasamy M, Jamieson S, Zaman A. Lack of gender difference and improved in-hospital mortality rates in patients with cardiogenic shock following primary percutaneous coronary intervention: a UK tertiary cardiac centre registry study. In: British Cardiovascular Society Annual Conference. 2012, Manchester, UK: BMJ Group.
  • Kunadian V, Veerasamy M, Jamieson S, Zaman A. Lack of gender difference and improved in-hospital mortality rates in patients with cardiogenic shock following primary percutaneous coronary intervention: a UK tertiary cardiac centre registry study. In: European Association of Percutaneous Cardiovascular Interventions (EUROPCR). 2012, Paris, France.
  • Kunadian V, Veerasamy M, Zaman A. Lack of gender difference and improved in-hospital mortality rates in patients with cardiogenic shock following primary percutaneous coronary intervention: a UK tertiary cardiac centre registry study. In: Congress of the European Society of Cardiology (ESC). 2012, Munchen, Germany: Oxford University Press.
  • Austin D, Bland J, Kunadian V. In-hospital Mortality Following Primary Angioplasty in the Setting of Cardiac Arrest is High and Varies Depending on Patient Location at the Time of Arrest: A UK Registry Database Study. In: Transcatheter Cardiovascular Therapeutics. 2012, Miami, Florida, USA: Elsevier Inc. In Press.
  • Kunadian V, Austin D, Bland J. In-hospital Mortality Following Primary Angioplasty in the Setting of Cardiac Arrest is High and Varies Depending on Patient Location at the Time of Arrest: A UK Registry Database Study. In: Transcatheter Cardiovascular Therapeutics (TCT) Symposium. 2012, Miami, Florida, USA: Elsevier Inc.
  • Kunadian V, Morley R, Adam Z, Muir D, Sutton A, Wright R, Hall J, Carter J, Swanson N, de Belder M. Percutaneous coronary intervention using radial access is associated with less radiation exposure to patients compared with femoral access. In: European Society of Cardiology Congress. 2011, Paris, France.
  • Kunadian V, Pugh A, Qiu WL. Percutaneous Coronary Intervention in Patients with Severe Left Ventricular Dysfunction: A Meta-analysis of 19 Studies. In: Journal of the American College of Cardiology: 23rd Annual Transcatheter Cardiovascular Therapeutics (TCT) Symposium. 2011, San Francisco, California, USA: Elsevier Inc.
  • Pride YB, Mohanavelu S, Giugliano RP, Newby LK, Zorkun C, Kunadian V, Braunwald E, Califf RM, Harrington RA, Gibson CM. Association Between Angiographic Complications During Percutaneous Coronary Intervention and Clinical Outcomes Among Patients with Acute Coronary Syndrome: An EARLY ACS Angiographic Substudy. In: American Heart Association Annual Congress. 2011, Orlando, Florida.
  • Kunadian V, Zorkun C, James S, Wu J, Muhammad A, Storey R, Steg G, Katus H, Emanuelsson H, Horrow J, Maya J, Wallentin L, Harrington R, Gibson CM. Angiographic outcomes in the platelet inhibition and platelet outcomes (PLATO) trial. In: American College of Cardiology: American College of Cardiology i2 summit. 2011, New Orleans, Los Angeles, USA: Elsevier Inc.
  • Kunadian V, Qiu W. Coronary Artery Bypass Surgery among Patients with Severely Impaired Left Ventricular Systolic Function is Associated with Improved Long-term Survival: A Meta-analysis of Observational Studies. In: Journal of the American College of Cardiology: Transcatheter Cardiovascular Therapeutics. 2010, Washington DC, USA: Elsevier Inc.
  • Kunadian V, Zaman A, Qiu W. Sodium Bicarbonate For The Prevention Of Contrast Induced Nephropathy: A Meta-Analysis. In: SCAI’s 32nd Annual Scientific Sessions. 2009, Las Vegas, Nevada, USA.
  • Ciaglo L, Karmpaliotis D, Kunadian V, Gibson W, Buros J, Zorkun C, Lew M, Harrington R, Palmer A, Ogando K, Biller L, Lord E, Williams S, Marble S, Alexander J, Gibson CM. Larger Saphenous Vein Grafts in Relation to Native Artery are Associated with Reduced TIMI Grade 3 Flow but Improved Myocardial Perfusion at 1 Year: A PREVENT IV Analysis . In: Circulation: American Heart Association Scientific Sessions. 2008, Orlando, Florida, USA: Lippincott Williams & Wilkins.

• Editorials

  • Pompei G, van de Hoef TP, den Ruijter HM, Kunadian V. Reading 2023 ESC ACS guidelines between the lines: Gaps in evidence in women. European Journal of Clinical Investigation 2024, 54(2), e14148.
  • Buchanan GL, Mehilli J, Kunadian V, Radu MD, Chieffo A, Chieffo A, Buchanan L, Radu M, Schupke S, Holmvang L, James S, Manzo-Silberman S, Piccaluga E, Mikhail G, Presbitero P, Kunadian V, Karam N, Morice M-C, Regar E, Al-Lamee R, Franzone A-S, Fraccaro C, Salvatella N, Souza L, Alasnag M, Sarno G, Amabile N, Kaluzna-Oleksy M. The invisible army of women in interventional cardiology: EAPCI Women mission to make them visible. EuroIntervention 2018, 14(11), E1158-E1159.
  • Grapsa J, Kunadian V, Capodanno D, Vidal-Perez R, Radu M, Christia P, Efimova A, Windecker S, Lancellotti P, Cosyns B, Donal E, Popescu BA, Habib G. Joint EACVI HIT/EAPCI young survey/ESC CoT survey: training and education for 'multimodality imaging in structural interventions': the rise of a new sub-specialty?. European Heart Journal Cardiovascular Imaging 2016, 17(12), 1432-1433.
  • Lima J, Kunadian V. Vitamin D: evidence for an association with coronary collateral circulation development?. Postepy W Kardiologii Interwencyjnej 2015, 11(3), 174-176.
  • Gibson CM, Zorkun C, Kunadian V. Intracoronary Administration of Abciximab in ST elevation Myocardial Infarction. Circulation 2008, 118(1), 6-8.
  • Kunadian V, Kelly D, Chapple CL, Williams D, Wright R, Stewart MJ, Hall JA, Sutton A, Davies A, Haywood J, de Belder MA. Cardiac catheterisation: radiation doses and lifetime risk of malignancy. Heart 2007, 93(3), 370-371.

• Letter

  • Ng Cheong Chung KJ, Kunadian V. Frailty assessment in the COVID-19 pandemic. Journal of Investigative Medicine 2020, 68(7), 1300-1301.

• Reviews

  • Jenkins K, Pompei G, Ganzorig N, Brown S, Beltrame J, Kunadian V. Vasospastic angina: a review on diagnostic approach and management. Therapeutic Advances in Cardiovascular Disease 2024, 18.
  • Kunadian V. Role of Physiology in the Management of Nonculprit Lesions in Acute Coronary Syndrome. New England Journal of Medicine 2024, 390(16), 1527-1529.
  • Ganzorig N, Pompei G, Jenkins K, Wang W, Rubino F, Gill K, Kunadian V. Role of physiology in the management of multivessel disease among patients with acute coronary syndrome. AsiaIntervention 2024, 10(3), 157-168.
  • Pavasini R, Biscaglia S, Kunadian V, Hakeem A, Campo G. Coronary artery disease management in older adults: revascularization and exercise training. European Heart Journal 2024, 45(31), 2811-2823.
  • Manzo-Silberman S, Hawranek M, Banerjee S, Kaluzna-Oleksy M, Alasnag M, Paradies V, Parapid B, Sabouret P, Wolczenko A, Kunadian V, Uchmanowicz I, Nizard J, Gilard M, Mehran R, Chieffo A. Call to action for acute myocardial infarction in women: International multi-disciplinary practical roadmap. European Heart Journal Open 2024, 4(6).
  • Behary Paray N, Ramphul K, Picker SM, Akkaramani S, Memon RA, Ahmed M, Aggarwal S, Dhaliwal JS, Mactaggart S, Jeelani S, Sombans S, Sakthivel H, Lohana P, Kunadian V, Ahmed R. Age-related disparities in complications among women with peripartum cardiomyopathy. Current Problems in Cardiology 2024, 49(8), 102647.
  • Byrne RA, Rossello X, Coughlan JJ, Barbato E, Berry C, Chieffo A, Claeys MJ, Dan G-A, Dweck MR, Galbraith M, Gilard M, Hinterbuchner L, Jankowska EA, Juni P, Kimura T, Kunadian V, Leosdottir M, Lorusso R, Pedretti RFE, Rigopoulos AG, Gimenez MR, Thiele H, Vranckx P, Wassmann S, Wenger NK, Ibanez B, Halvorsen S, James S, Abdelhamid M, Aboyans V, Marsan NA, Antoniou S, Asteggiano R, Back M, Capodanno D, Casado-Arroyo R, Cassese S, Celutkiene J, Cikes M, Collet J-P, Ducrocq G, Falk V, Fauchier L, Geisler T, Gorog DA, Holmvang L, Jaarsma T, Jones HW, Kober L, Koskinas KC, Kotecha D, Krychtiuk KA, Landmesser U, Lazaros G, Lewis BS, Lindahl B, Linhart A, Lochen M-L, Mamas MA, McEvoy JW, Mihaylova B, Mindham R, Mueller C, Neubeck L, Niebauer J, Nielsen JC, Niessner A, Paradies V, Pasquet AA, Petersen SE, Prescott E, Rakisheva A, Rocca B, Rosano GMC, Sade LE, Schiele F, Siller-Matula JM, Sticherling C, Storey RF, Thielmann M, Vrints C, Windecker S, Wiseth R, Witkowski A. 2023 ESC Guidelines for the management of acute coronary syndromes: Developed by the task force on the management of acute coronary syndromes of the European Society of Cardiology (ESC). European Heart Journal: Acute Cardiovascular Care 2024, 13(1), 55-161.
  • Kovacevic M, Pompei G, Kunadian V. Tailoring antiplatelet therapy in older patients with coronary artery disease. Platelets 2023, 34(1), 2285446.
  • Cartlidge T, Kovacevic M, Navarese EP, Werner G, Kunadian V. Role of percutaneous coronary intervention in the modern-day management of chronic coronary syndrome. Heart 2023, 109(19), 1429-1435.
  • Balasubramanian RN, Mills GB, Wilkinson C, Mehran R, Kunadian V. Role and relevance of risk stratification models in the modern-day management of non-ST elevation acute coronary syndromes. Heart 2023, 109(7), 504-510.
  • Ghobrial M, Bawamia B, Cartlidge T, Spyridopoulos I, Kunadian V, Zaman A, Egred M, McDiarmid A, Williams M, Farag M, Alkhalil M. Microvascular Obstruction in Acute Myocardial Infarction, a Potential Therapeutic Target. Journal of Clinical Medicine 2023, 12(18), 5934.
  • Kovacevic M, Jarakovic M, Milovancev A, Cankovic M, Petrovic M, Bjelobrk M, Ilic A, Srdanovic I, Tadic S, Dabovic D, Crnomarkovic B, Komazec N, Dracina N, Apostolovic S, Stanojevic D, Kunadian V. Contemporary review on spontaneous coronary artery dissection: insights into the angiographic finding and differential diagnosis. Frontiers in Cardiovascular Medicine 2023, 10, 1278453.
  • Gaudino M, Di Franco A, Cao D, Giustino G, Bairey Merz CN, Fremes SE, Kirtane AJ, Kunadian V, Lawton JS, Masterson Creber RM, Sandner S, Vogel B, Zwischenberger BA, Dangas GD, Mehran R. Sex-Related Outcomes of Medical, Percutaneous, and Surgical Interventions for Coronary Artery Disease: JACC Focus Seminar 3/7. Journal of the American College of Cardiology 2022, 79(14), 1407-1425.
  • Naylor-Wardle J, Rowland B, Kunadian V. Socioeconomic status and cardiovascular health in the COVID-19 pandemic. Heart 2021, 107, 358-365.
  • Raharjo DE, Kunadian V. Is There a Difference in Efficacy of Percutaneous Coronary Intervention for Focal and Diffuse Stable Coronary Artery Disease? [Commentary]. Circulation: Cardiovascular Interventions 2021, 14(8), e011013.
  • Gu S, Coakley D, Chan D, Beska B, Singh F, Edwards R, Kunadian V. Does Transcatheter Aortic Valve Implantation for Aortic Stenosis Impact on Cognitive Function?. Cardiology in Review 2020, 28(3), 135-139.
  • Rowland B, Kunadian V. Challenges in the management of older patients with acute coronary syndromes in the COVID-19 pandemic. Heart 2020, 106(17), 1296-1301.
  • Alasnag M, Mamas M, Fischman D, Brugaletta S, Safirstein J, Meier P, Kunadian V, Koltowski L, Sahni S, Alraies C, Gibson M. View point on social media use in interventional cardiology. Open Heart 2019, 6(1), e001031.
  • Vogel B, Claessen BE, Arnold SV, Chan D, Cohen DJ, Giannitsis E, Gibson CM, Goto S, Katus HA, Kerneis M, Kimura T, Kunadian V, Pinto DS, Shiomi H, Spertus JA, Steg PG, Mehran R. ST-segment elevation myocardial infarction. Nature Reviews Disease Primers 2019, 5, 39.
  • Chan D, Lawson L, Kunadian V. Management of older patients presenting with non-ST-elevation acute coronary syndrome. EuroIntervention 2018, 14(3), e258-e260.
  • Lima J, Batty J, Sinclair H, Kunadian V. MicroRNAs in Ischemic Heart Disease: From Pathophysiology to Potential Clinical Applications. Cardiology in Review 2017, 25(3), 117-125.
  • Sinclair H, Veerasamy M, Bourantas C, Egred M, Nair A, Calvert PA, Brugaletta S, Mintz GS, Kunadian V. The Role of Virtual Histology Intravascular Ultrasound in the Identification of Coronary Artery Plaque Vulnerability in Acute Coronary Syndromes. Cardiology in Review 2016, 24(6), 303-309.
  • Latimer J, Batty JA, Neely RD, Kunadian V. PCSK₉ inhibitors in the prevention of cardiovascular disease. Journal of Thrombosis and Thrombolysis 2016, 42(3), 405-419.
  • Ghoorah K, Campbell P, Kent A, Maznyczka A, Kunadian V. Obesity and cardiovascular outcomes: A review. European Heart Journal: Acute Cardiovascular Care 2016, 5(1), 77-85.
  • Batty JA, Subba S, Luke P, Gigi LWC, Sinclair H, Kunadian V. Intracoronary Imaging in the Detection of Vulnerable Plaques. Current Cardiology Reports 2016, 18(3), 28.
  • Tan YC, Sinclair H, Ghoorah K, Teoh X, Mehran R, Kunadian V. Gender differences in outcomes in patients with acute coronary syndrome in the current era: A review. European heart journal. Acute cardiovascular care 2016, 5(7), 51-60.
  • Batty JA, Lima JAC, Kunadian V. Direct cellular reprogramming for cardiac repair and regeneration. European Journal of Heart Failure 2016, 18(2), 145-156.
  • Sinclair H, Kunadian V. Coronary revascularisation in older patients with non-ST elevation acute coronary syndromes. Heart 2016, 102(6), 416-424.
  • Carpenter M, Sinclair H, Kunadian V. Carotid Intima Media Thickness and Its Utility as a Predictor of Cardiovascular Disease: A Review of Evidence. Cardiology in Review 2016, 24(2), 70-75.
  • Ahmed R, Ghoorah K, Kunadian V. Abdominal Aortic Aneurysms and Risk Factors for Adverse Events. Cardiology in Review 2016, 24(2), 88-93.
  • Backshall J, Ford GA, Bawamia B, Quinn L, Trenell M, Kunadian V. Physical Activity in the Management of Patients with Coronary Artery Disease: A Review. Cardiology in Review 2015, 23(1), 18-25.
  • Veerasamy M, Bagnall A, Neely D, Allen J, Sinclair H, Kunadian V. Endothelial Dysfunction and Coronary Artery Disease: A State of the Art Review. Cardiology in Review 2015, 23(3), 119-129.
  • Veerasamy M, Edwards R, Ford G, Kirkwood T, Newton J, Jones D, Kunadian V. Acute Coronary Syndrome among Older Patients: A Review. Cardiology in Review 2015, 23(1), 26-32.
  • Kunadian V, Ford GA, Bawamia B, Qiu W, Manson JE. Vitamin D deficiency and coronary artery disease: A review of the evidence. American Heart Journal 2014, 167(3), 283-291.
  • Ahmed R, Dunford J, Mehran R, Robson S, Kunadian V. Pre-Eclampsia and Future Cardiovascular Risk among Women: A Review. Journal of the American College of Cardiology 2014, 63(18), 1815-1822.
  • Veerasamy M, Ford GA, Neely D, Bagnall A, Macgowan G, Das R, Kunadian V. Association of Aging, Arterial Stiffness and Cardiovascular Disease: A Review. Cardiology in Review 2014, 22(5), 223-232.
  • Kunadian V, Dunford J, Swarbrick D, Halaby R, Patrick W, Maddaleni M, Gibson CM. Triple antiplatelet therapy and combinations with oral anticoagulants after stent implantation. Interventional Cardiology Clinics 2013. Submitted.
  • Bawamia B, Mehran R, Wei LQ, Kunadian V. Risk scores in acute coronary syndrome and percutaneous coronary intervention: A review. American Heart Journal 2013, 165(4), 441-450.
  • Ghoorah K, De Soyza A, Kunadian V. Increased Cardiovascular Risk in Patients with Chronic Obstructive Pulmonary Disease and the Potential Mechanisms Linking the Two Conditions: A Review. Cardiology in Review 2013, 21(4), 196-202.
  • Kunadian V, Harper A, Bawamia B, Zaman A. Drug eluting stents versus bare metal stents in primary PCI. Future Medicine 2013. In Press.
  • Navarese EP, Buffon A, Kozinski M, Obonska K, Rychter M, Kunadian V, Austin D, De Servi S, Sukiennik A, Kubica J. A critical overview on ticagrelor in acute coronary syndromes. QJM: An International Journal of Medicine 2013, 106(2), 105-115.
  • Pugh A, Bourke JP, Kunadian V. Sudden cardiac death among competitive adult athletes: a review. Postgraduate Medical Journal 2012, 88(1041), 382-390.
  • Kunadian V, Coats L, Kini A, Mehran R. Cardiogenic Shock in Women. Interventionals Cardiology Clinics 2012, 1(2), 231-243.
  • Kunadian V, Gibson CM. Recombinant tissue-type plasminogen activators: "Time Matters". Drugs of Today 2011, 47(7), 559-570.