CHY2101 : Organic Chemistry (Inactive)
- Inactive for Year: 2024/25
- Module Leader(s): Dr David Fulton
- Lecturer: Dr Julian Knight, Dr Cristina Navarro Reguero, Dr Michael Hall, Dr Hanno Kossen, Dr Johan Eriksson
- Practical Supervisor: Dr Zuleykha McMillan
- Owning School: Natural and Environmental Sciences
- Teaching Location: Newcastle City Campus
Semesters
Your programme is made up of credits, the total differs on programme to programme.
| Semester 1 Credit Value: | 10 |
| Semester 2 Credit Value: | 10 |
| ECTS Credits: | 10.0 |
| European Credit Transfer System | |
Aims
To provide a thorough understanding of the influence of conformational and stereoelectronic effects on the reactivity of organic compounds; to show how mechanisms of some organic reactions have been investigated and to present the currently accepted mechanisms of these reactions; to provide an understanding of mechanistic and synthetic chemistry; to consider the chemistry of aromatic and heteroaromatic systems and to develop experimental technique through practical sessions
Outline Of Syllabus
Aromatic Chemistry including Rearrangements
Dr DA Fulton
The definitions of aromaticity
Electrophilic aromatic substitution
Electrophilic aromatic substitution reactions of substituted benzenes
Synthesis of substituted benzenes; the reactions of benzene diazonium salts
Nucleophilic aromatic substitution; the chemistry of benzyne
Aromatic oxidations and reductions
Rearrangement reactions
Enolate chemistry
Dr MJ Hall
Formation of enolates and pKa
Enolate alkylation; O vs C alkylation, kinetic vs thermodynamic control, 1,3-dicarbonyls and the use of malonates in synthesis
The aldol reaction; aldol, dehydration of products, intramolecular aldol and cross aldol
Acylation of enolates; Claisen and Dieckmann condensations
Tandem processes; Darzens, Baylis Hillman, Robinson etc.
Enamines; formation and reactions
Stereochemistry and Mechanism
Dr JG Knight & Dr DA Fulton
Stereochemistry. Revision of basic concepts.
Conformations of acyclic compounds.
Conformations of 3-6 membered rings
Higher energy conformations of cyclohexanes
Stereocentres at atoms other than carbon. Chiral molecules which do not contain a stereocentre.
Topism
Intermolecular substitution reactions
Stereochemistry of SN2 and SN1
Revision
Nucleophilic substitution reactions in more detail
Elimination reactions in more detail
Investigating reaction mechanisms
Hammett relationships
Mechanisms of ester hydrolysis
Revision Seminar
Laboratory Course
Course organiser: Dr Z McMillan
Students do experiments dealing with the following transformations:
Stereoselective formation of a diol diastereoisomer and its conversion into an acetal
Electrophilic aromatic substitution of ferrocene
Amide bond formation
Aldol reaction
Investigations into SN1 and SN2 reactions
Teaching Methods
Teaching Activities
| Category | Activity | Number | Length | Student Hours | Comment |
|---|---|---|---|---|---|
| Guided Independent Study | Assessment preparation and completion | 20 | 1:00 | 20:00 | Revision of semester 2 material |
| Guided Independent Study | Assessment preparation and completion | 1 | 15:00 | 15:00 | Alternative online assessment of semester 2 material |
| Guided Independent Study | Assessment preparation and completion | 20 | 1:00 | 20:00 | Revision of semester 1 material |
| Guided Independent Study | Assessment preparation and completion | 1 | 15:00 | 15:00 | Alternative online assessment of semester 1 material |
| Guided Independent Study | Assessment preparation and completion | 1 | 12:00 | 12:00 | Laboratory skills assessment |
| Structured Guided Learning | Lecture materials | 40 | 1:00 | 40:00 | Online recordings of topics within the module |
| Guided Independent Study | Assessment preparation and completion | 1 | 20:00 | 20:00 | Laboratory online assessment |
| Scheduled Learning And Teaching Activities | Practical | 2 | 6:00 | 12:00 | Practical laboratory sessions 2 x 6h |
| Scheduled Learning And Teaching Activities | Small group teaching | 8 | 1:00 | 8:00 | Small group tutorials |
| Guided Independent Study | Independent study | 1 | 38:00 | 38:00 | Independent Study |
| Total | 200:00 |
Teaching Rationale And Relationship
The important basic principles of organic chemistry introduced in Stage 1 will be reinforced and built on by material covered in the online material. This will be supported by tutorials that will allow small groups of students to tackle an array of different problems associated with the lecture material and help prepare for the assessment. Practicals will reinforce elements of the lectures and extend the practical techniques and experience that the students gained in Stage 1.
Assessment Methods
The format of resits will be determined by the Board of Examiners
Other Assessment
| Description | Semester | When Set | Percentage | Comment |
|---|---|---|---|---|
| Practical/lab report | 2 | M | 30 | Laboratory online assessment |
| Computer assessment | 1 | M | 35 | Alternate assessment for sem 1 |
| Computer assessment | 2 | M | 35 | Alternate assessment for sem 2 |
Zero Weighted Pass/Fail Assessments
| Description | When Set | Comment |
|---|---|---|
| Practical/lab report | M | Laboratory Skills assessment |
Assessment Rationale And Relationship
There will be online examinations in semester 1 and 2 of this module. The online assessment will capture students' knowledge in Stereochemistry and also the students abilities to explain more complex concepts in organic chemistry.
Students are required to obtain at least 35% in the laboratory component in order for the examination mark to be included in the final module mark. Students who score
An alternative assessment will be set for any Semester 1 Study Abroad student taking this module, who will not be in Newcastle during the January assessment period.
Reading Lists
Timetable
- Timetable Website: www.ncl.ac.uk/timetable/
- CHY2101's Timetable